Click here to switch to the map view.

The map label for this gene is ais [H]

Identifier: 77456957

GI number: 77456957

Start: 857428

End: 858099

Strand: Direct

Name: ais [H]

Synonym: Pfl01_0729

Alternate gene names: 77456957

Gene position: 857428-858099 (Clockwise)

Preceding gene: 77456954

Following gene: 77456958

Centisome position: 13.32

GC content: 64.14

Gene sequence:

>672_bases
GTGGAATTGAGACTGAGTCTGTTCGGCGTCAAGCGCTCGATTGATCTGAGCGGTCTGGCCCGTTTTCGAAACACCTGGGT
GGTATTGGCGGCCTCGGTGCTGGTCATTCCTTTGACCCTCTGGCTGCTGGCCCCGGCGGCGGTGCCTGACCTTGCCCACG
GCAATGTGGCCGGGGCGCAGGCGCTGAAGGACGGTTGGAGCAAAGGCGACATCATCGTGCTGGTGCGCCACGTCGAGCGC
TGCGATCACTCCAAAGCCGCTTGCCTGAGCGGCCACGATGGCATCACCGATCGCTCGCGCAGTGTCGCGGTGAGCGTCGG
CGCGCAGTTCGAGCAGTTGGGCCTGGACAACGCCGACGTCTACAACAGCCCGATGGTGCGCACGGTGCAGACCGCCGGCT
ACATGTTCAACAAGGCCGCGACCGGCGAAGACTGGCTGATCAGTTGCAAGGGCCGGATGCTGCAGGACGCGCTCGCGCAC
AAGGTCCCGGGACGCAACCTGATTCTGGTGACCCACAGCGAATGCATTGCGCAGCTGGAAAAAGACCTCAAGGTGCCGGC
CTCGACCCTCGGGTACGGCGCATCGCTGTTTGTTTCCGCCGCCAGCCCGGCGGCCCCACAGATGCTCGGCTTCATTGAAG
CCTCCGACTGGCGCACGGTGACTACCCAATGA

Upstream 100 bases:

>100_bases
AACAGGCACTCACAAGACTTTTTTCACATGGGTTTCACTGCCTACCCACGCCGTGCTCTCTAACCTCGCCGCATCGAATG
ACAAGTGATGGCGGCTTTTT

Downstream 100 bases:

>100_bases
AATCCCGCTTTTACGCTTACAACTTCGGCATCCCGCTGCTCTGCGCAGCCGTGGTTTTTCTGATGTTCGACATGACCAAC
ATCGACATCGCTTTCAGCAA

Product: phosphoglycerate/bisphosphoglycerate mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MELRLSLFGVKRSIDLSGLARFRNTWVVLAASVLVIPLTLWLLAPAAVPDLAHGNVAGAQALKDGWSKGDIIVLVRHVER
CDHSKAACLSGHDGITDRSRSVAVSVGAQFEQLGLDNADVYNSPMVRTVQTAGYMFNKAATGEDWLISCKGRMLQDALAH
KVPGRNLILVTHSECIAQLEKDLKVPASTLGYGASLFVSAASPAAPQMLGFIEASDWRTVTTQ

Sequences:

>Translated_223_residues
MELRLSLFGVKRSIDLSGLARFRNTWVVLAASVLVIPLTLWLLAPAAVPDLAHGNVAGAQALKDGWSKGDIIVLVRHVER
CDHSKAACLSGHDGITDRSRSVAVSVGAQFEQLGLDNADVYNSPMVRTVQTAGYMFNKAATGEDWLISCKGRMLQDALAH
KVPGRNLILVTHSECIAQLEKDLKVPASTLGYGASLFVSAASPAAPQMLGFIEASDWRTVTTQ
>Mature_223_residues
MELRLSLFGVKRSIDLSGLARFRNTWVVLAASVLVIPLTLWLLAPAAVPDLAHGNVAGAQALKDGWSKGDIIVLVRHVER
CDHSKAACLSGHDGITDRSRSVAVSVGAQFEQLGLDNADVYNSPMVRTVQTAGYMFNKAATGEDWLISCKGRMLQDALAH
KVPGRNLILVTHSECIAQLEKDLKVPASTLGYGASLFVSAASPAAPQMLGFIEASDWRTVTTQ

Specific function: Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. Ais subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788586, Length=115, Percent_Identity=33.9130434782609, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR011310 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: NA

Molecular weight: Translated: 23923; Mature: 23923

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRLSLFGVKRSIDLSGLARFRNTWVVLAASVLVIPLTLWLLAPAAVPDLAHGNVAGAQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
ALKDGWSKGDIIVLVRHVERCDHSKAACLSGHDGITDRSRSVAVSVGAQFEQLGLDNADV
HHHCCCCCCCEEEEEEHHHHCCCCCCEEECCCCCCCCCCCEEEEEECCHHHHHCCCCCCC
YNSPMVRTVQTAGYMFNKAATGEDWLISCKGRMLQDALAHKVPGRNLILVTHSECIAQLE
CCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEEECHHHHHHHH
KDLKVPASTLGYGASLFVSAASPAAPQMLGFIEASDWRTVTTQ
HHHCCCHHHHCCCCEEEEECCCCCCCHHHEEEECCCCEEECCC
>Mature Secondary Structure
MELRLSLFGVKRSIDLSGLARFRNTWVVLAASVLVIPLTLWLLAPAAVPDLAHGNVAGAQ
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
ALKDGWSKGDIIVLVRHVERCDHSKAACLSGHDGITDRSRSVAVSVGAQFEQLGLDNADV
HHHCCCCCCCEEEEEEHHHHCCCCCCEEECCCCCCCCCCCEEEEEECCHHHHHCCCCCCC
YNSPMVRTVQTAGYMFNKAATGEDWLISCKGRMLQDALAHKVPGRNLILVTHSECIAQLE
CCCCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHCCCCCEEEEEECHHHHHHHH
KDLKVPASTLGYGASLFVSAASPAAPQMLGFIEASDWRTVTTQ
HHHCCCHHHHCCCCEEEEECCCCCCCHHHEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA