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The map label for this gene is cobJ [H]

Identifier: 77456835

GI number: 77456835

Start: 699328

End: 701031

Strand: Direct

Name: cobJ [H]

Synonym: Pfl01_0607

Alternate gene names: 77456835

Gene position: 699328-701031 (Clockwise)

Preceding gene: 77456834

Following gene: 77456836

Centisome position: 10.86

GC content: 65.32

Gene sequence:

>1704_bases
ATGACCCATTCCACACCGGCCATCGTCATTCTCGGCCAGGGCGCGCTGGCCACGGCCCGTCGCCTTCAGCAGGTCTATCC
GGCTGCAAAGATTCACGGCCTCAATGGACGCGTCGAAGGCGCCGACCTGACTTACAGCGACTTCGGCGCGACCCTGCGCG
AGTTGTATCAACAGGACACGCCGATCATTGCCCTGTGCGCGGCCGGCATTGTCATTCGCACCCTGGCGCCGCTGTTGCTG
GAGAAAGGTGTCGAGCCACCGGTGCTCGCCGTGGCTGAAGACGGCAGCGCCGTGGTGCCGCTGCTCGGCGGCTTGGGCGG
GGTGAATGTCATGGCCCGCGAGATCGCAGCTGGGCTTGAAGTGGCAGCGGCGATTACCACCAGCGGTGAGTTGCGTTTCG
GCACCTGCCTGCTCAACCCGCCCGGCGGTTATGCCCTTGGCGATCTGGAGCAGGGCAAGCGTTTTGTCTCCGATCTGCTC
GCCGGCCACAGCGTGCGCATCGACGGCGCTGCGCCGTGGCTTGAGCAGGCGCAACTGCCGGAAGATCCACAGGCACAGCG
CTCGATTCATGTGGGTAGCGCCGCTCGCGCGGCGAATACCAGTGAGTTACTGATTTATCCGCGCAGCGTGGCGGTGGCGG
TGGGTTCGTCAGTGACTGACGTGCCGGGCACCCTTCGCGATGCATTGCAGCAGGCCGGTGTGGCGATTCAATCGCTGGCC
TGTCTGGTGGCGGCCGATGCTCAGATGGCCAGTCCGGCATTGCGTGAAGCCGCACTTGAACTGGCAGTGCCGCTGCGCTT
TGTCGCGCCGGCGAATGACATCGGTGAGTTGGTTCGCGATGCAGTCCCCGGCGCTCGAATCATCACAACATCCCGAGACA
TTGCCATCGCCGTGGCCGAACAGCCGCTGGATGTTTCGCAGATCGGTCGTCCGCGCGGCCGTCTGGCCGTCATCGGCCTC
GGCCCGGGCGCGGCAGAGCTGATGGTGCCTGCGGTGAAAGCCGAACTGGCCCGCGCCACCGACGTTCTCGGTTACGAAAC
CTACGTGCGCATGGCCGGCCCCTTCCGCGACGATCAGGTGCAGCATTGCACCGACAACCGCGAAGAAATGCAGCGTGCCC
GTCACGCCTTCAGACTGGCCGCTCAGGGACGTTCGGTGATTGTGGTTTCGTCGGGCGATCCGGGCGTGTTCGCCATGGCG
GCAGCGGTGCTCGAAGCGTTGCACGAGTCGACGGACCCGGCGTGGCACAGCGTCGATCTGGAAATCCTGCCGGGTGTTTC
GGCGTCGCTCGCCACCGCCGCTCAGGCCGGTGCACCGCTGGGCCATGACTTCTGCGTGATGTCGCTGTCGGACAACCTCA
AGCCGTGGTCGATCATCGAAAAGCGTCTGGATCTGGCCGCCGAGGCGGATCTGGCGCTGGCCTTCTACAACCCGATCTCT
CGTTCGCGACCGTGGCAGTTGGGCCGAGCCCTGGAAATCGTTGCGCAACACCGTACATCGCAGACACCGGTGGTGCTCGG
GCGTGACATCGGCCGGCCGGGGCAGACGTTGCGGGTGACGACGCTCGGCGCGTTGACCCCGGATCAAGTGGACATGCGCA
CTATGGTGTTGATCGGTTCGTCCACCACCTGCACGTTCCCCCGCGCCGAAGGCGGGAAGTGGGTCTACACGCCACGTTGG
TACGGTAGCAAGCCAGCGGGCTGA

Upstream 100 bases:

>100_bases
CCATGGCCAACCAGAAGATCGTGTCGCTGGATGAGGTCGAGCCGATGTCATCGCCGTACTTCTCGCTGATCATTGTTCCC
GGCGAACGGTGGCAAGGCTG

Downstream 100 bases:

>100_bases
GCCTCTCGCTCCGACGTATCAGGAAGCTGGAGCAGTACTAAATAAAACAGGGCGCGAACAGGAGTTCGCGACCCTGTTTT
TTTTGGGGACAAGGAAAGTT

Product: precorrin-3 methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase; Precorrin-3 methyltransferase [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTHSTPAIVILGQGALATARRLQQVYPAAKIHGLNGRVEGADLTYSDFGATLRELYQQDTPIIALCAAGIVIRTLAPLLL
EKGVEPPVLAVAEDGSAVVPLLGGLGGVNVMAREIAAGLEVAAAITTSGELRFGTCLLNPPGGYALGDLEQGKRFVSDLL
AGHSVRIDGAAPWLEQAQLPEDPQAQRSIHVGSAARAANTSELLIYPRSVAVAVGSSVTDVPGTLRDALQQAGVAIQSLA
CLVAADAQMASPALREAALELAVPLRFVAPANDIGELVRDAVPGARIITTSRDIAIAVAEQPLDVSQIGRPRGRLAVIGL
GPGAAELMVPAVKAELARATDVLGYETYVRMAGPFRDDQVQHCTDNREEMQRARHAFRLAAQGRSVIVVSSGDPGVFAMA
AAVLEALHESTDPAWHSVDLEILPGVSASLATAAQAGAPLGHDFCVMSLSDNLKPWSIIEKRLDLAAEADLALAFYNPIS
RSRPWQLGRALEIVAQHRTSQTPVVLGRDIGRPGQTLRVTTLGALTPDQVDMRTMVLIGSSTTCTFPRAEGGKWVYTPRW
YGSKPAG

Sequences:

>Translated_567_residues
MTHSTPAIVILGQGALATARRLQQVYPAAKIHGLNGRVEGADLTYSDFGATLRELYQQDTPIIALCAAGIVIRTLAPLLL
EKGVEPPVLAVAEDGSAVVPLLGGLGGVNVMAREIAAGLEVAAAITTSGELRFGTCLLNPPGGYALGDLEQGKRFVSDLL
AGHSVRIDGAAPWLEQAQLPEDPQAQRSIHVGSAARAANTSELLIYPRSVAVAVGSSVTDVPGTLRDALQQAGVAIQSLA
CLVAADAQMASPALREAALELAVPLRFVAPANDIGELVRDAVPGARIITTSRDIAIAVAEQPLDVSQIGRPRGRLAVIGL
GPGAAELMVPAVKAELARATDVLGYETYVRMAGPFRDDQVQHCTDNREEMQRARHAFRLAAQGRSVIVVSSGDPGVFAMA
AAVLEALHESTDPAWHSVDLEILPGVSASLATAAQAGAPLGHDFCVMSLSDNLKPWSIIEKRLDLAAEADLALAFYNPIS
RSRPWQLGRALEIVAQHRTSQTPVVLGRDIGRPGQTLRVTTLGALTPDQVDMRTMVLIGSSTTCTFPRAEGGKWVYTPRW
YGSKPAG
>Mature_566_residues
THSTPAIVILGQGALATARRLQQVYPAAKIHGLNGRVEGADLTYSDFGATLRELYQQDTPIIALCAAGIVIRTLAPLLLE
KGVEPPVLAVAEDGSAVVPLLGGLGGVNVMAREIAAGLEVAAAITTSGELRFGTCLLNPPGGYALGDLEQGKRFVSDLLA
GHSVRIDGAAPWLEQAQLPEDPQAQRSIHVGSAARAANTSELLIYPRSVAVAVGSSVTDVPGTLRDALQQAGVAIQSLAC
LVAADAQMASPALREAALELAVPLRFVAPANDIGELVRDAVPGARIITTSRDIAIAVAEQPLDVSQIGRPRGRLAVIGLG
PGAAELMVPAVKAELARATDVLGYETYVRMAGPFRDDQVQHCTDNREEMQRARHAFRLAAQGRSVIVVSSGDPGVFAMAA
AVLEALHESTDPAWHSVDLEILPGVSASLATAAQAGAPLGHDFCVMSLSDNLKPWSIIEKRLDLAAEADLALAFYNPISR
SRPWQLGRALEIVAQHRTSQTPVVLGRDIGRPGQTLRVTTLGALTPDQVDMRTMVLIGSSTTCTFPRAEGGKWVYTPRWY
GSKPAG

Specific function: Methyltransferase that catalyzes the methylation of C-17 in precorrin-3B to form precorrin-4 [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006363 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.131 [H]

Molecular weight: Translated: 59606; Mature: 59475

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHSTPAIVILGQGALATARRLQQVYPAAKIHGLNGRVEGADLTYSDFGATLRELYQQDT
CCCCCCEEEEECCCHHHHHHHHHHHCCHHEEECCCCEECCCCCCHHHHHHHHHHHHHCCC
PIIALCAAGIVIRTLAPLLLEKGVEPPVLAVAEDGSAVVPLLGGLGGVNVMAREIAAGLE
CEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHCCCCCHHHHHHHHHHHHH
VAAAITTSGELRFGTCLLNPPGGYALGDLEQGKRFVSDLLAGHSVRIDGAAPWLEQAQLP
EEEEEECCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCC
EDPQAQRSIHVGSAARAANTSELLIYPRSVAVAVGSSVTDVPGTLRDALQQAGVAIQSLA
CCCCHHHEEECCCHHCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHCHHHHHHH
CLVAADAQMASPALREAALELAVPLRFVAPANDIGELVRDAVPGARIITTSRDIAIAVAE
HHHHCCHHHCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCEEEEECCCEEEEEEC
QPLDVSQIGRPRGRLAVIGLGPGAAELMVPAVKAELARATDVLGYETYVRMAGPFRDDQV
CCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCH
QHCTDNREEMQRARHAFRLAAQGRSVIVVSSGDPGVFAMAAAVLEALHESTDPAWHSVDL
HHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECE
EILPGVSASLATAAQAGAPLGHDFCVMSLSDNLKPWSIIEKRLDLAAEADLALAFYNPIS
EEECCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCC
RSRPWQLGRALEIVAQHRTSQTPVVLGRDIGRPGQTLRVTTLGALTPDQVDMRTMVLIGS
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEC
STTCTFPRAEGGKWVYTPRWYGSKPAG
CCEEECCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
THSTPAIVILGQGALATARRLQQVYPAAKIHGLNGRVEGADLTYSDFGATLRELYQQDT
CCCCCEEEEECCCHHHHHHHHHHHCCHHEEECCCCEECCCCCCHHHHHHHHHHHHHCCC
PIIALCAAGIVIRTLAPLLLEKGVEPPVLAVAEDGSAVVPLLGGLGGVNVMAREIAAGLE
CEEEHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEHHHHCCCCCHHHHHHHHHHHHH
VAAAITTSGELRFGTCLLNPPGGYALGDLEQGKRFVSDLLAGHSVRIDGAAPWLEQAQLP
EEEEEECCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHCCCC
EDPQAQRSIHVGSAARAANTSELLIYPRSVAVAVGSSVTDVPGTLRDALQQAGVAIQSLA
CCCCHHHEEECCCHHCCCCCCEEEEECCCEEEEECCCCCCCCHHHHHHHHHHCHHHHHHH
CLVAADAQMASPALREAALELAVPLRFVAPANDIGELVRDAVPGARIITTSRDIAIAVAE
HHHHCCHHHCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCCEEEEECCCEEEEEEC
QPLDVSQIGRPRGRLAVIGLGPGAAELMVPAVKAELARATDVLGYETYVRMAGPFRDDQV
CCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCH
QHCTDNREEMQRARHAFRLAAQGRSVIVVSSGDPGVFAMAAAVLEALHESTDPAWHSVDL
HHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECE
EILPGVSASLATAAQAGAPLGHDFCVMSLSDNLKPWSIIEKRLDLAAEADLALAFYNPIS
EEECCCCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCC
RSRPWQLGRALEIVAQHRTSQTPVVLGRDIGRPGQTLRVTTLGALTPDQVDMRTMVLIGS
CCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEECCCCCCCCCCEEEEEEEC
STTCTFPRAEGGKWVYTPRWYGSKPAG
CCEEECCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2211521; 8226690 [H]