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The map label for this gene is motA [H]

Identifier: 77456740

GI number: 77456740

Start: 594207

End: 595058

Strand: Direct

Name: motA [H]

Synonym: Pfl01_0512

Alternate gene names: 77456740

Gene position: 594207-595058 (Clockwise)

Preceding gene: 77456736

Following gene: 77456741

Centisome position: 9.23

GC content: 59.98

Gene sequence:

>852_bases
ATGGCTAAAATTATCGGCATCATCGTCGTATTCGCGAGCGTGCTCGGCGGATACGTGCTCTCCCACGGCAAGATTGCCGC
CCTGATCCAGCCCTTCGAGGTGATGATCATCGGCGGTGCGGCACTCGGAGCCTTCCTCCAGGCCAACCCCGGCTACATGA
CGATGCACGTGCTCAAGAAATCCCTGAGCATGTTCAGTTCGCGTTTCAGCCACACGTTCTATCTGGAAGTGCTTGGCCTG
ATCTACGAGATCCTCAACAAGAGCCGCCGTGAAGGCATGATGGCCATCGAAGGCGACATCGAAGACGCCGCCGCGAGCCC
GATCTTCGCCAAGTACCCGGCGGTACTGAAAGACGAACGCATGACCGCGTTCATCTGCGACTACCTGCGCATCATGTCCT
CCGGCAACATGGCTCCCCACGAGCTGGAAGGCCTGTTCGACATGGAACTGTACAGCCTGAAGGAAGACCTCGAGCATCCG
TCCCACGCGGTGAACGGCATTGCCGACGCCATGCCGGGTTTCGGTATCGTCGCGGCGGTACTCGGTATCGTGGTGACCAT
GGCCTCGCTGGGTGAAGGCGATCAGAAATCCATCGGCCTGCACGTGGGTGCGGCACTTGTGGGTACCTTCTTCGGTATTC
TCGCGGCGTACGGTTTCTTCGGTCCTTTGGCGCACTCCCTGGCGCACGATGCCAAGGAAGAGCTGAACGTCTACGAAGCC
ATCAAGGCCTCTCTGGTGGCTTCGGCTTCCGGCATGCCGCCGTCGCTGGCTGTCGAGTTCGGTCGCAAGGTGCTGTACCC
GGCTCACCGTCCAAGCTTTGCCGAGCTGGAACAAGCCGTTCGCGGTCGTTAA

Upstream 100 bases:

>100_bases
TGGCTATAGTCTGGCGCAGTTTTGCCGATAAGTAGAAGAAGAGATTTTTTAACTTCCGAATATGACCTTGAACCCGACTT
AAACAAGTACCTTTCTACCT

Downstream 100 bases:

>100_bases
GTCATGGAAAATAACCAGCCGATAATCATCAAGCGCGTCAAGCGCATCGCCGGCGGGCATCACGGCGGGGCGTGGAAGAT
CGCCTTCGCCGACTTCGCGA

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MAKIIGIIVVFASVLGGYVLSHGKIAALIQPFEVMIIGGAALGAFLQANPGYMTMHVLKKSLSMFSSRFSHTFYLEVLGL
IYEILNKSRREGMMAIEGDIEDAAASPIFAKYPAVLKDERMTAFICDYLRIMSSGNMAPHELEGLFDMELYSLKEDLEHP
SHAVNGIADAMPGFGIVAAVLGIVVTMASLGEGDQKSIGLHVGAALVGTFFGILAAYGFFGPLAHSLAHDAKEELNVYEA
IKASLVASASGMPPSLAVEFGRKVLYPAHRPSFAELEQAVRGR

Sequences:

>Translated_283_residues
MAKIIGIIVVFASVLGGYVLSHGKIAALIQPFEVMIIGGAALGAFLQANPGYMTMHVLKKSLSMFSSRFSHTFYLEVLGL
IYEILNKSRREGMMAIEGDIEDAAASPIFAKYPAVLKDERMTAFICDYLRIMSSGNMAPHELEGLFDMELYSLKEDLEHP
SHAVNGIADAMPGFGIVAAVLGIVVTMASLGEGDQKSIGLHVGAALVGTFFGILAAYGFFGPLAHSLAHDAKEELNVYEA
IKASLVASASGMPPSLAVEFGRKVLYPAHRPSFAELEQAVRGR
>Mature_282_residues
AKIIGIIVVFASVLGGYVLSHGKIAALIQPFEVMIIGGAALGAFLQANPGYMTMHVLKKSLSMFSSRFSHTFYLEVLGLI
YEILNKSRREGMMAIEGDIEDAAASPIFAKYPAVLKDERMTAFICDYLRIMSSGNMAPHELEGLFDMELYSLKEDLEHPS
HAVNGIADAMPGFGIVAAVLGIVVTMASLGEGDQKSIGLHVGAALVGTFFGILAAYGFFGPLAHSLAHDAKEELNVYEAI
KASLVASASGMPPSLAVEFGRKVLYPAHRPSFAELEQAVRGR

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=284, Percent_Identity=41.5492957746479, Blast_Score=223, Evalue=8e-60,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30313; Mature: 30182

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIGIIVVFASVLGGYVLSHGKIAALIQPFEVMIIGGAALGAFLQANPGYMTMHVLKK
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHEEECHHHHHHHHHCCCCHHHHHHHHH
SLSMFSSRFSHTFYLEVLGLIYEILNKSRREGMMAIEGDIEDAAASPIFAKYPAVLKDER
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCHHHHCCHHHHHCH
MTAFICDYLRIMSSGNMAPHELEGLFDMELYSLKEDLEHPSHAVNGIADAMPGFGIVAAV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
LGIVVTMASLGEGDQKSIGLHVGAALVGTFFGILAAYGFFGPLAHSLAHDAKEELNVYEA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKASLVASASGMPPSLAVEFGRKVLYPAHRPSFAELEQAVRGR
HHHHHHHHCCCCCHHHHHHHCHHHCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
AKIIGIIVVFASVLGGYVLSHGKIAALIQPFEVMIIGGAALGAFLQANPGYMTMHVLKK
HHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHEEECHHHHHHHHHCCCCHHHHHHHHH
SLSMFSSRFSHTFYLEVLGLIYEILNKSRREGMMAIEGDIEDAAASPIFAKYPAVLKDER
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCHHHHCCHHHHHCH
MTAFICDYLRIMSSGNMAPHELEGLFDMELYSLKEDLEHPSHAVNGIADAMPGFGIVAAV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHH
LGIVVTMASLGEGDQKSIGLHVGAALVGTFFGILAAYGFFGPLAHSLAHDAKEELNVYEA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IKASLVASASGMPPSLAVEFGRKVLYPAHRPSFAELEQAVRGR
HHHHHHHHCCCCCHHHHHHHCHHHCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]