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The map label for this gene is yghZ [H]

Identifier: 77456480

GI number: 77456480

Start: 297732

End: 298769

Strand: Direct

Name: yghZ [H]

Synonym: Pfl01_0252

Alternate gene names: 77456480

Gene position: 297732-298769 (Clockwise)

Preceding gene: 77456479

Following gene: 77456488

Centisome position: 4.62

GC content: 63.01

Gene sequence:

>1038_bases
ATGACTTACACCGCTGCCGAAAACCGCTATGACTCCATCCCTTACCGCCGCGTCGGACGCAGCGGTCTGGTGCTGCCGGC
GCTGTCTCTGGGCCTGTGGCACAACTTCGGCGACAGCACGCCGATCGACACCCAGCGCTCGTTGCTGCGCACGGCGTTCG
ACCTGGGCATCAACCACTTCGACCTGGCCAACAACTATGGCCCGCCCTACGGCAGCGCCGAGATCAACTTCGGCCGTTTG
CTGCGCGAAGACTTCAAGCAGTACCGCGATGAACTGATCATCTCCAGCAAGGCCGGTTGGGACATGTGGCCCGGCCCTTA
CGGCCAGGGTGGCGGTTCGCGCAAATACGTGCTGGCCAGCCTCGACCAGAGCCTGCAACGCCTGGGCCTGGACTATGTGG
ATATTTTCTATTCGCACCGCTTCGACCCGGACACGCCACTGGAAGAAACCGCCAGCGCCCTTGCCACGGCGGTGCAGCAG
GGCAAGGCGCTGTACATCGGCATCTCGTCGTACTCCGGAGTGAAAACCCGCGAAATCGCCGCATTGCTCAAAGAGTGGAA
AGTGCCGCTGCTGATCCACCAACCGGCCTACAACCTGCTCAACCGCTGGGTGGAAAAGGACCTGCTCGACACCACCGACG
AGCTCGGCACTGGCGTGATTGCCTTCACCCCGCTGGCGCAGGGTCTGCTGACCGACAAATACCTCAACGGCGTGCCGGCG
GATGCGCGGGTCAACCGTCCGGGCGGTGGTTCTTTGCAGGCTTCGCACTTGTCCGAGGCCAACATCGCTCACGTTCGGGC
GCTGAACGAGATCGCCAAGCGTCGTGGCCAGAGCCTGGCGCAACTGGCATTGGCGTGGACACTGCGGGATCCGCGGGTGA
CTTCGGCGCTGATCGGCGCGAGCCGGCCGGAGCAGATTGTCGAGAACGTCGGGGCGTTGAAGAATCTGAGCTTCAGTGCT
GAGGAACTGGCGGAGATTGACCGGTTTGCCCAGGAGGGCGGGATCAATCTTTGGGAGAAGCCTTCGACGGCGGAGTGA

Upstream 100 bases:

>100_bases
CGAGGGCCGGACCTTGCGCCAGAACCTTGGCCTCGCCCGGCCCGGCAACAGATTTGCGTAGCAATCGACACCTGATTCAA
GACCGACAAGAGAGGATTCG

Downstream 100 bases:

>100_bases
TCGAAACTGGGGCGGGTCAGATAGATCCCCCCTCACCCCAGCCCTCTCCCCAAGGGGGGGGCGAGGGGGAAAGGGAGCAA
ATCTCCGTGCTTTTCAAACC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTYTAAENRYDSIPYRRVGRSGLVLPALSLGLWHNFGDSTPIDTQRSLLRTAFDLGINHFDLANNYGPPYGSAEINFGRL
LREDFKQYRDELIISSKAGWDMWPGPYGQGGGSRKYVLASLDQSLQRLGLDYVDIFYSHRFDPDTPLEETASALATAVQQ
GKALYIGISSYSGVKTREIAALLKEWKVPLLIHQPAYNLLNRWVEKDLLDTTDELGTGVIAFTPLAQGLLTDKYLNGVPA
DARVNRPGGGSLQASHLSEANIAHVRALNEIAKRRGQSLAQLALAWTLRDPRVTSALIGASRPEQIVENVGALKNLSFSA
EELAEIDRFAQEGGINLWEKPSTAE

Sequences:

>Translated_345_residues
MTYTAAENRYDSIPYRRVGRSGLVLPALSLGLWHNFGDSTPIDTQRSLLRTAFDLGINHFDLANNYGPPYGSAEINFGRL
LREDFKQYRDELIISSKAGWDMWPGPYGQGGGSRKYVLASLDQSLQRLGLDYVDIFYSHRFDPDTPLEETASALATAVQQ
GKALYIGISSYSGVKTREIAALLKEWKVPLLIHQPAYNLLNRWVEKDLLDTTDELGTGVIAFTPLAQGLLTDKYLNGVPA
DARVNRPGGGSLQASHLSEANIAHVRALNEIAKRRGQSLAQLALAWTLRDPRVTSALIGASRPEQIVENVGALKNLSFSA
EELAEIDRFAQEGGINLWEKPSTAE
>Mature_344_residues
TYTAAENRYDSIPYRRVGRSGLVLPALSLGLWHNFGDSTPIDTQRSLLRTAFDLGINHFDLANNYGPPYGSAEINFGRLL
REDFKQYRDELIISSKAGWDMWPGPYGQGGGSRKYVLASLDQSLQRLGLDYVDIFYSHRFDPDTPLEETASALATAVQQG
KALYIGISSYSGVKTREIAALLKEWKVPLLIHQPAYNLLNRWVEKDLLDTTDELGTGVIAFTPLAQGLLTDKYLNGVPAD
ARVNRPGGGSLQASHLSEANIAHVRALNEIAKRRGQSLAQLALAWTLRDPRVTSALIGASRPEQIVENVGALKNLSFSAE
ELAEIDRFAQEGGINLWEKPSTAE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504825, Length=319, Percent_Identity=35.7366771159875, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI27436969, Length=319, Percent_Identity=35.7366771159875, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI27436966, Length=323, Percent_Identity=34.3653250773994, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI27436964, Length=323, Percent_Identity=34.3653250773994, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI27436962, Length=323, Percent_Identity=34.3653250773994, Blast_Score=185, Evalue=4e-47,
Organism=Homo sapiens, GI27436971, Length=329, Percent_Identity=34.9544072948328, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI41327764, Length=242, Percent_Identity=30.9917355371901, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI41152114, Length=116, Percent_Identity=41.3793103448276, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI223718702, Length=242, Percent_Identity=29.7520661157025, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789375, Length=345, Percent_Identity=66.6666666666667, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI87081735, Length=325, Percent_Identity=34.4615384615385, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789199, Length=352, Percent_Identity=30.6818181818182, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788070, Length=322, Percent_Identity=29.8136645962733, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788081, Length=308, Percent_Identity=26.6233766233766, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787674, Length=293, Percent_Identity=25.2559726962457, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=25.8823529411765, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323998, Length=307, Percent_Identity=27.0358306188925, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=277, Percent_Identity=27.4368231046931, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322615, Length=253, Percent_Identity=25.296442687747, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319951, Length=305, Percent_Identity=26.5573770491803, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24640980, Length=353, Percent_Identity=27.7620396600567, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI45549126, Length=353, Percent_Identity=27.7620396600567, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24646155, Length=353, Percent_Identity=27.7620396600567, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 38045; Mature: 37914

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYTAAENRYDSIPYRRVGRSGLVLPALSLGLWHNFGDSTPIDTQRSLLRTAFDLGINHF
CCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCE
DLANNYGPPYGSAEINFGRLLREDFKQYRDELIISSKAGWDMWPGPYGQGGGSRKYVLAS
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHHHH
LDQSLQRLGLDYVDIFYSHRFDPDTPLEETASALATAVQQGKALYIGISSYSGVKTREIA
HHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
ALLKEWKVPLLIHQPAYNLLNRWVEKDLLDTTDELGTGVIAFTPLAQGLLTDKYLNGVPA
HHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCC
DARVNRPGGGSLQASHLSEANIAHVRALNEIAKRRGQSLAQLALAWTLRDPRVTSALIGA
CCEECCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
SRPEQIVENVGALKNLSFSAEELAEIDRFAQEGGINLWEKPSTAE
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TYTAAENRYDSIPYRRVGRSGLVLPALSLGLWHNFGDSTPIDTQRSLLRTAFDLGINHF
CCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCE
DLANNYGPPYGSAEINFGRLLREDFKQYRDELIISSKAGWDMWPGPYGQGGGSRKYVLAS
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCHHHHHH
LDQSLQRLGLDYVDIFYSHRFDPDTPLEETASALATAVQQGKALYIGISSYSGVKTREIA
HHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
ALLKEWKVPLLIHQPAYNLLNRWVEKDLLDTTDELGTGVIAFTPLAQGLLTDKYLNGVPA
HHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCC
DARVNRPGGGSLQASHLSEANIAHVRALNEIAKRRGQSLAQLALAWTLRDPRVTSALIGA
CCEECCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
SRPEQIVENVGALKNLSFSAEELAEIDRFAQEGGINLWEKPSTAE
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]