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The map label for this gene is gntR [H]

Identifier: 77456477

GI number: 77456477

Start: 292902

End: 293939

Strand: Reverse

Name: gntR [H]

Synonym: Pfl01_0249

Alternate gene names: 77456477

Gene position: 293939-292902 (Counterclockwise)

Preceding gene: 77456481

Following gene: 77456476

Centisome position: 4.57

GC content: 63.68

Gene sequence:

>1038_bases
TTGAGCGAAGAAAAGCCCCGCAAACGCCGTGGCGCCGGCCGCGTGACCCTCAACGCGGTGGCGCGCCAGGCCGGTGTTTC
GGCGATCACCGTGTCGCGCTATTTCAACCAGCCGGAACAGGTCTCGCCCGAGCGTCGCGAACGGATCGCGGCGGTGGTCG
CCGAACTGGGTTATGTGCCGAATCTGGTGGCCGGCGGACTCGCCTCTGCACGGGGGAAAATCGTCGGCATGGTGATCCCG
AACATCTCCGGGCCGATCTTTGCCAACACCATTCAGGGCTTCAGCGACACCCTCAGCCGTCACGGTTATCAGCTGTTGCT
GGCATCGAGTTACTTCAGCACCGAGCAGGAAGAAAACGCCGTGCGGGCGTTCCTCGGCTGGTCGCCGGCGGCGCTGGTGG
TCACCAGTCACTTCCACAGCGCGGGCACGGAAAAGATGCTCGCCGAAGCGGATATTCCGGTGGTTGAAACCTGGGATTAC
CAACCGGATCGCGAGCCGATGCAGATCGGCTTTTCGCACTTTGAAGTGGGGGTCAGTGCCGCTCGTTATCTGCATGACAA
AGGCTACCGGCGAATCGCCTTCGTGCAGAACAGCGCACCCGGCGACTTCAGCGCACTGGAGCGCCGCGACGGTTATGCGG
CGACCGTGCGTGAGCTAGGACTTGAGCCCTGGGTATTCGCACCCGACACCGATCGAGCCCCGTTCGAGGCCGGCAAGCAA
GCGATGCAAGCGCTGATGAACGCCTCACCCCGCCCGGACGCGATCATCTTCGCCAACGACAACCTCGCCGCCGGCGGCCT
GCTCGCCGGACAACGCGCCGGCCTTAAGATCCCCGAAGACTGCGCCGTCCTCGGCTTCGGCGACTACCCGTTCGCCGAAA
TGCTGCTGCCGAGCCTGAGCACCATCAAACCGCCCGCGCTGGAGATCGGTGTACTGGCGGCGACGCGGGTGCTGGAAAGT
CTGGGCGTGCTGCCGAGTGATGAGGTGCAGCGGTTGAATCTGCTGCAATGCACAGTCATTGAGCGGGAAAGTATCTGA

Upstream 100 bases:

>100_bases
GTTAGCGCTAACATCGCCAGTATTGGCAAGCCGGACATAGACCGTCCAATACTGAAAAATTACTTTTATATGCGTTTTGG
TTTTTAAGAAGGGTCGAGCC

Downstream 100 bases:

>100_bases
CGAATATGGCGTGGGCGGGTTTGGCTATGCTCTAAATGAAACCGAGGTGGCGCCTTCGCGGGCAAGCCCGCTCCCACAGG
TTCTGTGTTGCGTACAGAAT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSEEKPRKRRGAGRVTLNAVARQAGVSAITVSRYFNQPEQVSPERRERIAAVVAELGYVPNLVAGGLASARGKIVGMVIP
NISGPIFANTIQGFSDTLSRHGYQLLLASSYFSTEQEENAVRAFLGWSPAALVVTSHFHSAGTEKMLAEADIPVVETWDY
QPDREPMQIGFSHFEVGVSAARYLHDKGYRRIAFVQNSAPGDFSALERRDGYAATVRELGLEPWVFAPDTDRAPFEAGKQ
AMQALMNASPRPDAIIFANDNLAAGGLLAGQRAGLKIPEDCAVLGFGDYPFAEMLLPSLSTIKPPALEIGVLAATRVLES
LGVLPSDEVQRLNLLQCTVIERESI

Sequences:

>Translated_345_residues
MSEEKPRKRRGAGRVTLNAVARQAGVSAITVSRYFNQPEQVSPERRERIAAVVAELGYVPNLVAGGLASARGKIVGMVIP
NISGPIFANTIQGFSDTLSRHGYQLLLASSYFSTEQEENAVRAFLGWSPAALVVTSHFHSAGTEKMLAEADIPVVETWDY
QPDREPMQIGFSHFEVGVSAARYLHDKGYRRIAFVQNSAPGDFSALERRDGYAATVRELGLEPWVFAPDTDRAPFEAGKQ
AMQALMNASPRPDAIIFANDNLAAGGLLAGQRAGLKIPEDCAVLGFGDYPFAEMLLPSLSTIKPPALEIGVLAATRVLES
LGVLPSDEVQRLNLLQCTVIERESI
>Mature_344_residues
SEEKPRKRRGAGRVTLNAVARQAGVSAITVSRYFNQPEQVSPERRERIAAVVAELGYVPNLVAGGLASARGKIVGMVIPN
ISGPIFANTIQGFSDTLSRHGYQLLLASSYFSTEQEENAVRAFLGWSPAALVVTSHFHSAGTEKMLAEADIPVVETWDYQ
PDREPMQIGFSHFEVGVSAARYLHDKGYRRIAFVQNSAPGDFSALERRDGYAATVRELGLEPWVFAPDTDRAPFEAGKQA
MQALMNASPRPDAIIFANDNLAAGGLLAGQRAGLKIPEDCAVLGFGDYPFAEMLLPSLSTIKPPALEIGVLAATRVLESL
GVLPSDEVQRLNLLQCTVIERESI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=305, Percent_Identity=31.1475409836066, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1790715, Length=309, Percent_Identity=30.0970873786408, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1790369, Length=323, Percent_Identity=27.2445820433437, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=29.5819935691318, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790194, Length=326, Percent_Identity=30.0613496932515, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=27.3529411764706, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=26.5993265993266, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1789202, Length=342, Percent_Identity=26.9005847953216, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786540, Length=311, Percent_Identity=27.0096463022508, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787906, Length=339, Percent_Identity=24.188790560472, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787580, Length=308, Percent_Identity=25.6493506493506, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786268, Length=293, Percent_Identity=25.938566552901, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37369; Mature: 37238

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKPRKRRGAGRVTLNAVARQAGVSAITVSRYFNQPEQVSPERRERIAAVVAELGYVP
CCCCCCHHHCCCCCEEHHHHHHHHCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCH
NLVAGGLASARGKIVGMVIPNISGPIFANTIQGFSDTLSRHGYQLLLASSYFSTEQEENA
HHHHCCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHH
VRAFLGWSPAALVVTSHFHSAGTEKMLAEADIPVVETWDYQPDREPMQIGFSHFEVGVSA
HHHHHCCCCCEEEEEHHHHHCCHHHHHHHCCCCEEEECCCCCCCCHHHHCHHHHHHHHHH
ARYLHDKGYRRIAFVQNSAPGDFSALERRDGYAATVRELGLEPWVFAPDTDRAPFEAGKQ
HHHHHHCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHCCCCCEEECCCCCCCCHHHHHH
AMQALMNASPRPDAIIFANDNLAAGGLLAGQRAGLKIPEDCAVLGFGDYPFAEMLLPSLS
HHHHHHCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
TIKPPALEIGVLAATRVLESLGVLPSDEVQRLNLLQCTVIERESI
HCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCC
>Mature Secondary Structure 
SEEKPRKRRGAGRVTLNAVARQAGVSAITVSRYFNQPEQVSPERRERIAAVVAELGYVP
CCCCCHHHCCCCCEEHHHHHHHHCCCEEEHHHHHCCCCCCCHHHHHHHHHHHHHHCCCH
NLVAGGLASARGKIVGMVIPNISGPIFANTIQGFSDTLSRHGYQLLLASSYFSTEQEENA
HHHHCCHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCHHHHH
VRAFLGWSPAALVVTSHFHSAGTEKMLAEADIPVVETWDYQPDREPMQIGFSHFEVGVSA
HHHHHCCCCCEEEEEHHHHHCCHHHHHHHCCCCEEEECCCCCCCCHHHHCHHHHHHHHHH
ARYLHDKGYRRIAFVQNSAPGDFSALERRDGYAATVRELGLEPWVFAPDTDRAPFEAGKQ
HHHHHHCCCEEEEEEECCCCCCHHHHHHCCCHHHHHHHCCCCCEEECCCCCCCCHHHHHH
AMQALMNASPRPDAIIFANDNLAAGGLLAGQRAGLKIPEDCAVLGFGDYPFAEMLLPSLS
HHHHHHCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
TIKPPALEIGVLAATRVLESLGVLPSDEVQRLNLLQCTVIERESI
HCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]