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The map label for this gene is cat1 [H]

Identifier: 77456339

GI number: 77456339

Start: 112317

End: 113810

Strand: Reverse

Name: cat1 [H]

Synonym: Pfl01_0111

Alternate gene names: 77456339

Gene position: 113810-112317 (Counterclockwise)

Preceding gene: 77456340

Following gene: 77456338

Centisome position: 1.77

GC content: 61.65

Gene sequence:

>1494_bases
ATGTACCGTGACCGTATTCGCCTGCCTTCGTTGTTGGATAAAGTGATGAGCGCCGCCGACGCCGCTGCGCTGATTGAGGA
CGGCATGACCGTCGGCATGAGCGGCTTCACCCGCGCTGGCGAAGCCAAGGCCGTGCCCCATGCGCTGGCCGAGCGAGCCA
AGGTCACGCCGCTGAAGATCAGCCTGATGACCGGCGCCAGCCTGGGCAACGATCTCGACAAGCAACTGACCGAGGCCGGC
GTCCTGTCCCGGCGCATGCCGTTCCAGGTCGACAGCACCCTGCGCAAGGCGATCAACGCCGGCGAAGTGATGTTCATCGA
CCAGCACCTGTCGGAAACCGTCGAGCAACTGCGCAACCAGCAACTGAAACTGCCAGACATCGCCGTGATCGAGGCCGTGG
CCATCACCGAACAGGGCCATATCGTGCCGACCACTTCGGTGGGCAACTCGGCGAGCTTCGCGATCTTCGCCAAACACGTG
ATCGTCGAGATCAACCTGGCGCACAACGCTAACCTGGAAGGTCTGCATGACATCTATATTCCAACCTATCGTCCGACCCG
CACCCCGATCCCGCTGGTAAAAGTCGACGATCGCATCGGCAGCACCGCGATCCCGATCCCGCCGGAGAAAATCGTCGCCA
TCGTCATTACCCAGCAGTCGGACTCGCCGTCCACCGTGTCATCGCCGGATGTCGATACCAAAGCCATCGCCGATCACCTG
ATCACCTTCCTCAAGCAGGAAGTCGATGCCGGGCGCATGACCAACAAGCTCGGCCCACTGCAGGCCGGGATCGGCAACAT
TGCCAACGCGGTGATGTGCGGCCTGATCGATTCGCCGTTCGAAGAACTGACCATGTATTCCGAAGTGCTGCAGGACTCGA
CCTTCGACCTGATTGATGCGGGCAAACTGAGCTTCGCCTCGGGCAGTTCGATCACCCTTTCGGAGCGGCGCAACAGCGAC
GTGTTCGGCAATCTGGAGAAGTACAAGGACAAGCTGGTACTGCGTCCCCAGGAAATCTCCAACCACCCTGAAGTGGTGCG
ACGCCTGGGTATCATCGGCATCAACACGGCCCTTGAGTTCGACATCTATGGCAACGTCAACTCCACCCACGTCTGCGGCA
CGCGGATGATGAACGGCATCGGCGGCTCGGGCGACTTCGCGCGCAACGCACACCTGGCGGTGTTCGTGACCAAGTCGATC
GCCAAGGGCGGCGCGATTTCCAGCGTGGTGCCGATGGTCAGCCACGTCGACCACACCGAGCATGACGTCGACATCCTGGT
GACCGAGGTGGGCCTGGCCGACCTGCGCGGCCTGGCGCCACGGGAACGCGCCCGGGTCATCATCGATAATTGCGTGCACC
CGGATTACCGCTCGGCGCTGAACGATTACTTCGAAAAAGCCTGTGCGATCGGCGGCCACACCCCGCACATCCTGCGTGAC
GCCCTGAGCTGGCACATCAATCTGGAAGAAACCGGACGCATGCTGGCGGTGTAA

Upstream 100 bases:

>100_bases
GCTAAATAGACGCCTCGTTTGCGACCTTGGTAGCGGGACAGGCGCTCGCGAAATTCACTAGACTGCGCATCCTGCTACTC
GCTGCCCGAGAAAATAATCC

Downstream 100 bases:

>100_bases
TCCGCACAGATTTTCCGCTGGCGCAAACACAGTTTCGTCAGCGGAATTTTGAAAACCGCCGCAGCCGTCAAAAACTGTAC
TGCTGTACCGGTCGTTTCCT

Product: Acetyl-CoA hydrolase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MYRDRIRLPSLLDKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKISLMTGASLGNDLDKQLTEAG
VLSRRMPFQVDSTLRKAINAGEVMFIDQHLSETVEQLRNQQLKLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKHV
IVEINLAHNANLEGLHDIYIPTYRPTRTPIPLVKVDDRIGSTAIPIPPEKIVAIVITQQSDSPSTVSSPDVDTKAIADHL
ITFLKQEVDAGRMTNKLGPLQAGIGNIANAVMCGLIDSPFEELTMYSEVLQDSTFDLIDAGKLSFASGSSITLSERRNSD
VFGNLEKYKDKLVLRPQEISNHPEVVRRLGIIGINTALEFDIYGNVNSTHVCGTRMMNGIGGSGDFARNAHLAVFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRSALNDYFEKACAIGGHTPHILRD
ALSWHINLEETGRMLAV

Sequences:

>Translated_497_residues
MYRDRIRLPSLLDKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKISLMTGASLGNDLDKQLTEAG
VLSRRMPFQVDSTLRKAINAGEVMFIDQHLSETVEQLRNQQLKLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKHV
IVEINLAHNANLEGLHDIYIPTYRPTRTPIPLVKVDDRIGSTAIPIPPEKIVAIVITQQSDSPSTVSSPDVDTKAIADHL
ITFLKQEVDAGRMTNKLGPLQAGIGNIANAVMCGLIDSPFEELTMYSEVLQDSTFDLIDAGKLSFASGSSITLSERRNSD
VFGNLEKYKDKLVLRPQEISNHPEVVRRLGIIGINTALEFDIYGNVNSTHVCGTRMMNGIGGSGDFARNAHLAVFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRSALNDYFEKACAIGGHTPHILRD
ALSWHINLEETGRMLAV
>Mature_497_residues
MYRDRIRLPSLLDKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKISLMTGASLGNDLDKQLTEAG
VLSRRMPFQVDSTLRKAINAGEVMFIDQHLSETVEQLRNQQLKLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKHV
IVEINLAHNANLEGLHDIYIPTYRPTRTPIPLVKVDDRIGSTAIPIPPEKIVAIVITQQSDSPSTVSSPDVDTKAIADHL
ITFLKQEVDAGRMTNKLGPLQAGIGNIANAVMCGLIDSPFEELTMYSEVLQDSTFDLIDAGKLSFASGSSITLSERRNSD
VFGNLEKYKDKLVLRPQEISNHPEVVRRLGIIGINTALEFDIYGNVNSTHVCGTRMMNGIGGSGDFARNAHLAVFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRSALNDYFEKACAIGGHTPHILRD
ALSWHINLEETGRMLAV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=46.9135802469136, Blast_Score=431, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17538151, Length=222, Percent_Identity=31.0810810810811, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563853, Length=218, Percent_Identity=31.1926605504587, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319456, Length=515, Percent_Identity=44.4660194174757, Blast_Score=425, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 53839; Mature: 53839

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRDRIRLPSLLDKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCCEEEE
SLMTGASLGNDLDKQLTEAGVLSRRMPFQVDSTLRKAINAGEVMFIDQHLSETVEQLRNQ
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QLKLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKHVIVEINLAHNANLEGLHDIYI
CCCCCCHHHHEEEEEECCCCEEEECCCCCCCCHHEEEEEEEEEEEECCCCCCCCCEEEEE
PTYRPTRTPIPLVKVDDRIGSTAIPIPPEKIVAIVITQQSDSPSTVSSPDVDTKAIADHL
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
ITFLKQEVDAGRMTNKLGPLQAGIGNIANAVMCGLIDSPFEELTMYSEVLQDSTFDLIDA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
GKLSFASGSSITLSERRNSDVFGNLEKYKDKLVLRPQEISNHPEVVRRLGIIGINTALEF
CCEEECCCCEEEECCCCCCCCCCCHHHHHHHEEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVCGTRMMNGIGGSGDFARNAHLAVFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCCCC
HDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRSALNDYFEKACAIGGHTPHILRD
CCCEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHINLEETGRMLAV
HHHEEEEHHHCCCEECC
>Mature Secondary Structure
MYRDRIRLPSLLDKVMSAADAAALIEDGMTVGMSGFTRAGEAKAVPHALAERAKVTPLKI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCCCCEEEE
SLMTGASLGNDLDKQLTEAGVLSRRMPFQVDSTLRKAINAGEVMFIDQHLSETVEQLRNQ
EEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHCC
QLKLPDIAVIEAVAITEQGHIVPTTSVGNSASFAIFAKHVIVEINLAHNANLEGLHDIYI
CCCCCCHHHHEEEEEECCCCEEEECCCCCCCCHHEEEEEEEEEEEECCCCCCCCCEEEEE
PTYRPTRTPIPLVKVDDRIGSTAIPIPPEKIVAIVITQQSDSPSTVSSPDVDTKAIADHL
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHH
ITFLKQEVDAGRMTNKLGPLQAGIGNIANAVMCGLIDSPFEELTMYSEVLQDSTFDLIDA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCC
GKLSFASGSSITLSERRNSDVFGNLEKYKDKLVLRPQEISNHPEVVRRLGIIGINTALEF
CCEEECCCCEEEECCCCCCCCCCCHHHHHHHEEECHHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVCGTRMMNGIGGSGDFARNAHLAVFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCCCC
HDVDILVTEVGLADLRGLAPRERARVIIDNCVHPDYRSALNDYFEKACAIGGHTPHILRD
CCCEEEEECCCHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHINLEETGRMLAV
HHHEEEEHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]