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The map label for this gene is speB [H]

Identifier: 76819842

GI number: 76819842

Start: 2464594

End: 2465556

Strand: Direct

Name: speB [H]

Synonym: BURPS1710b_A2027

Alternate gene names: 76819842

Gene position: 2464594-2465556 (Clockwise)

Preceding gene: 76818933

Following gene: 76818081

Centisome position: 77.46

GC content: 68.02

Gene sequence:

>963_bases
ATGAATGAAACGCTCTATGGCGACGGCGCGATCCGCCGCCCTTCCATCTACGGTTCCTCGGTCGAAAACACTTACGCGGG
CGTGCTGTCGTTCATGCGGCGCAACTACACGCGCGATCTCGGCGGTGTCGACGTCGCCGTCTGCGGCGTGCCGCTCGATC
TCGCGACGACGTTCCGCTCCGGCGCGCGCCTGGGCCCTGCGGCGGTACGCGCGGCGAGCGTGCAGCTTGCCGAACTGCGC
CCGTACCCTTGGGGGTTCGATCCGTTCGACGATCTCGCGGTGATCGACTATGGCGACTGCTGGTTCGACGCGCACAATCC
GCTGTCGATCAAGCCCGCGATCGTCGAGCACGCGCGCACGATCCTGCAATCGGGCGCGGCGATGCTGACGTTGGGCGGCG
ATCACTACATCACGTATCCGCTGCTGATCGCGCACGCACAGCGGCACGGCAAGCCGCTGTCGCTGATTCACTTCGACGCG
CATTGCGACACCTGGGCCGACGACGCGCCCGACAGCCTCAATCACGGCACGATGTTCTACAAGGCGGTCAACGAAGGGCT
GATCGATCCGAAGACGTCGGTGCAGGTCGGCATCCGTACGTGGAACGACGATTACCTCGGCATCCACGTGCTCGACGCCG
CCTGGGTGCACGAGCACGGGCCGCGCGCGACGGCCGAGCGCATCGCGTCGATCGTCGGCGGCCAGCCGGCGTATCTGACG
TTCGACATCGATTGCCTCGATCCCGCGTTCGCGCCGGGCACGGGCACGCCGGTCGCGGGCGGGCTGTCGTCCGCGCAGGC
GCTCGCGATCGTGCGCGGTCTCGGCGGCGTGAACCTGATCGGTGCGGACGTCGTCGAAGTCGCGCCCGCGTATGACCAGA
GCGAGATCACCGCGATCGCGGCCGCGCACGTCGCGTGCGATCTGCTGTGCCTGTGGCGGCAGCGCAAGACGGGCGCGCGC
TGA

Upstream 100 bases:

>100_bases
CGCAACGCGCCGCCGCGTTCCCAATGAATCCGATCGCCGGCCCGTTCGCCTTTTTCGAAGCGGCATCGCGGGCGGGCCGG
TTTCTCCACCGGGTCATTCG

Downstream 100 bases:

>100_bases
CGCGCCGCGGCGAGCGGTGCTCGCGCGCCGCATGAACGCGGGGCATGAACGCGGGGCGCGAGCACCGGGCGGCGGGCGCA
GGCAACCACCCGACCCTCCC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNETLYGDGAIRRPSIYGSSVENTYAGVLSFMRRNYTRDLGGVDVAVCGVPLDLATTFRSGARLGPAAVRAASVQLAELR
PYPWGFDPFDDLAVIDYGDCWFDAHNPLSIKPAIVEHARTILQSGAAMLTLGGDHYITYPLLIAHAQRHGKPLSLIHFDA
HCDTWADDAPDSLNHGTMFYKAVNEGLIDPKTSVQVGIRTWNDDYLGIHVLDAAWVHEHGPRATAERIASIVGGQPAYLT
FDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGVNLIGADVVEVAPAYDQSEITAIAAAHVACDLLCLWRQRKTGAR

Sequences:

>Translated_320_residues
MNETLYGDGAIRRPSIYGSSVENTYAGVLSFMRRNYTRDLGGVDVAVCGVPLDLATTFRSGARLGPAAVRAASVQLAELR
PYPWGFDPFDDLAVIDYGDCWFDAHNPLSIKPAIVEHARTILQSGAAMLTLGGDHYITYPLLIAHAQRHGKPLSLIHFDA
HCDTWADDAPDSLNHGTMFYKAVNEGLIDPKTSVQVGIRTWNDDYLGIHVLDAAWVHEHGPRATAERIASIVGGQPAYLT
FDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGVNLIGADVVEVAPAYDQSEITAIAAAHVACDLLCLWRQRKTGAR
>Mature_320_residues
MNETLYGDGAIRRPSIYGSSVENTYAGVLSFMRRNYTRDLGGVDVAVCGVPLDLATTFRSGARLGPAAVRAASVQLAELR
PYPWGFDPFDDLAVIDYGDCWFDAHNPLSIKPAIVEHARTILQSGAAMLTLGGDHYITYPLLIAHAQRHGKPLSLIHFDA
HCDTWADDAPDSLNHGTMFYKAVNEGLIDPKTSVQVGIRTWNDDYLGIHVLDAAWVHEHGPRATAERIASIVGGQPAYLT
FDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGVNLIGADVVEVAPAYDQSEITAIAAAHVACDLLCLWRQRKTGAR

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=294, Percent_Identity=44.2176870748299, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI10947139, Length=305, Percent_Identity=28.5245901639344, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1789306, Length=306, Percent_Identity=48.0392156862745, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 34276; Mature: 34276

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETLYGDGAIRRPSIYGSSVENTYAGVLSFMRRNYTRDLGGVDVAVCGVPLDLATTFRS
CCCCEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHC
GARLGPAAVRAASVQLAELRPYPWGFDPFDDLAVIDYGDCWFDAHNPLSIKPAIVEHART
CCCCCHHHHHHHHEEHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCHHHHHHHHH
ILQSGAAMLTLGGDHYITYPLLIAHAQRHGKPLSLIHFDAHCDTWADDAPDSLNHGTMFY
HHHCCCEEEEECCCCEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEE
KAVNEGLIDPKTSVQVGIRTWNDDYLGIHVLDAAWVHEHGPRATAERIASIVGGQPAYLT
EEHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEHHHHCCCCHHHHHHHHHHHCCCCEEEE
FDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGVNLIGADVVEVAPAYDQSEITAIA
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHHCCCCCCHHHHHHH
AAHVACDLLCLWRQRKTGAR
HHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNETLYGDGAIRRPSIYGSSVENTYAGVLSFMRRNYTRDLGGVDVAVCGVPLDLATTFRS
CCCCEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHC
GARLGPAAVRAASVQLAELRPYPWGFDPFDDLAVIDYGDCWFDAHNPLSIKPAIVEHART
CCCCCHHHHHHHHEEHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCHHHHHHHHH
ILQSGAAMLTLGGDHYITYPLLIAHAQRHGKPLSLIHFDAHCDTWADDAPDSLNHGTMFY
HHHCCCEEEEECCCCEEHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEE
KAVNEGLIDPKTSVQVGIRTWNDDYLGIHVLDAAWVHEHGPRATAERIASIVGGQPAYLT
EEHHCCCCCCCCCEEEEEEECCCCEEEEEEEEEHHHHCCCCHHHHHHHHHHHCCCCEEEE
FDIDCLDPAFAPGTGTPVAGGLSSAQALAIVRGLGGVNLIGADVVEVAPAYDQSEITAIA
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCHHHHHCCCCCCHHHHHHH
AAHVACDLLCLWRQRKTGAR
HHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]