Click here to switch to the map view.

The map label for this gene is copA [H]

Identifier: 76819005

GI number: 76819005

Start: 2443368

End: 2444561

Strand: Direct

Name: copA [H]

Synonym: BURPS1710b_A2009

Alternate gene names: 76819005

Gene position: 2443368-2444561 (Clockwise)

Preceding gene: 76817946

Following gene: 76818098

Centisome position: 76.79

GC content: 66.42

Gene sequence:

>1194_bases
ATGGCGAAAGCCGCGACGCAGCCGCCGCTCGCGCCGCCGAACGGCCGCCCGTACACGCCCGTCGTCACGCTCAACGGCTG
GACGCTGCCGTGGCGAATGAAGAACGGCTGGAAGGAATTTCACCTGATCGCCGAGCCCGTCGTGCGCGAGCTCGCGCCGG
GGATGAACGCGCATCTGTGGGGCTACAACGGTCAGACGCCGGGGCCGACGATCGAGGCGGTCGAAGGCGAGAAGGTTCGC
GTCTTCGTCACGAACCGGCTGCCCGAGCATACGACGGTCCATTGGCACGGGATGCTGCTGCCGTGCGGGATGGACGGCGT
CGGCGGCCTCACGCAGCCGCACATCCCGCCCGGCAAGACTTTCGTCTATGAGTTCCAGCTCGAGAAGGCCGGCACGTTCA
TGTACCACCCGCACGCGGACGAGATGGTGCAGATGGCGATGGGCATGATGGGCACGTTCATCGTGCATCCGAAGGATCGC
GGCGCGATGCCGGCCGATCGCGACTTCGTGTTCCTGATGTCCGCGTACGACATCGATCCGGGCAGCTTCACGCCGCGCGT
GAACGAGATGACGGACTTCAACATGTGGACGTGGAACGCGCGCGTGTTTCCCGGCATCGATCCGCTGCCGGTGCGCGCGG
GCGACCGCGTGCGGATTCGTTTCGGCAACCTGACGATGACCAATCACCCGATTCATCTGCATGGCTACGCATTCGAAGTG
GCGGGCACCGACGGCGGCTGGATTGCGCCCGCCGCGCGCTGGCCCGAAGTGACGGTCGACGTCGCGGTGGGCCAGATGCG
CGCGATCGAGTTCACCGCGAATCGGCCGGGCGACTGGGCGTTCCATTGCCACAAGTCGCACCACACGATGAATGCGATGG
GGCATCAGGTGCCGAACCTGATCGGCGTGCCGCAGCAGGATCTCGCGAAGCGGATCAACAAGCTCGTGCCCGACTACATG
GCGATGGGCAGCACGGGCGGCGCGATGGGAACCATGGAGATGCCGCTGCCCGAGAACACGCTGCCGATGATGACGGGCAC
GGGGCCGTTCGGCCCGCTCGAGATGGGCGGCATGTTCACCGTCGTGAAGGTGAGGCAGGGCCTCGGGCGCAACGATTATC
GGGACCCGGGCTGGTTCAGGCATCCGAAGGGAACCGTCGCGTACGAATACGCGGGCGCGCTGCCGGACGACTGA

Upstream 100 bases:

>100_bases
GGTGTCACGTCGAACTTTTCTCGGCGGCTCCGGCGCCGCGCTGCTCGGCGCGGCGCTCGTCAGCAAGGCGGGCGCCGCGT
CGCTGCCCGAAGCGCCGACG

Downstream 100 bases:

>100_bases
GCAGGCGCGCGGCCCGGGCCGGTCCGGCCGGGCGCGCGGGCCGAACGACAACCGAGTTTCACCGGGCCGGACGGCGGCGT
CCGGTCCGTTTTCCCACCCC

Product: multicopper oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MAKAATQPPLAPPNGRPYTPVVTLNGWTLPWRMKNGWKEFHLIAEPVVRELAPGMNAHLWGYNGQTPGPTIEAVEGEKVR
VFVTNRLPEHTTVHWHGMLLPCGMDGVGGLTQPHIPPGKTFVYEFQLEKAGTFMYHPHADEMVQMAMGMMGTFIVHPKDR
GAMPADRDFVFLMSAYDIDPGSFTPRVNEMTDFNMWTWNARVFPGIDPLPVRAGDRVRIRFGNLTMTNHPIHLHGYAFEV
AGTDGGWIAPAARWPEVTVDVAVGQMRAIEFTANRPGDWAFHCHKSHHTMNAMGHQVPNLIGVPQQDLAKRINKLVPDYM
AMGSTGGAMGTMEMPLPENTLPMMTGTGPFGPLEMGGMFTVVKVRQGLGRNDYRDPGWFRHPKGTVAYEYAGALPDD

Sequences:

>Translated_397_residues
MAKAATQPPLAPPNGRPYTPVVTLNGWTLPWRMKNGWKEFHLIAEPVVRELAPGMNAHLWGYNGQTPGPTIEAVEGEKVR
VFVTNRLPEHTTVHWHGMLLPCGMDGVGGLTQPHIPPGKTFVYEFQLEKAGTFMYHPHADEMVQMAMGMMGTFIVHPKDR
GAMPADRDFVFLMSAYDIDPGSFTPRVNEMTDFNMWTWNARVFPGIDPLPVRAGDRVRIRFGNLTMTNHPIHLHGYAFEV
AGTDGGWIAPAARWPEVTVDVAVGQMRAIEFTANRPGDWAFHCHKSHHTMNAMGHQVPNLIGVPQQDLAKRINKLVPDYM
AMGSTGGAMGTMEMPLPENTLPMMTGTGPFGPLEMGGMFTVVKVRQGLGRNDYRDPGWFRHPKGTVAYEYAGALPDD
>Mature_396_residues
AKAATQPPLAPPNGRPYTPVVTLNGWTLPWRMKNGWKEFHLIAEPVVRELAPGMNAHLWGYNGQTPGPTIEAVEGEKVRV
FVTNRLPEHTTVHWHGMLLPCGMDGVGGLTQPHIPPGKTFVYEFQLEKAGTFMYHPHADEMVQMAMGMMGTFIVHPKDRG
AMPADRDFVFLMSAYDIDPGSFTPRVNEMTDFNMWTWNARVFPGIDPLPVRAGDRVRIRFGNLTMTNHPIHLHGYAFEVA
GTDGGWIAPAARWPEVTVDVAVGQMRAIEFTANRPGDWAFHCHKSHHTMNAMGHQVPNLIGVPQQDLAKRINKLVPDYMA
MGSTGGAMGTMEMPLPENTLPMMTGTGPFGPLEMGGMFTVVKVRQGLGRNDYRDPGWFRHPKGTVAYEYAGALPDD

Specific function: Required for the copper-inducible expression of copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=109, Percent_Identity=35.7798165137615, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323703, Length=110, Percent_Identity=40, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321067, Length=107, Percent_Identity=36.4485981308411, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI18859919, Length=109, Percent_Identity=39.4495412844037, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 44033; Mature: 43902

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAATQPPLAPPNGRPYTPVVTLNGWTLPWRMKNGWKEFHLIAEPVVRELAPGMNAHLW
CCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEE
GYNGQTPGPTIEAVEGEKVRVFVTNRLPEHTTVHWHGMLLPCGMDGVGGLTQPHIPPGKT
CCCCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCE
FVYEFQLEKAGTFMYHPHADEMVQMAMGMMGTFIVHPKDRGAMPADRDFVFLMSAYDIDP
EEEEEEECCCCEEEECCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEEEEECCC
GSFTPRVNEMTDFNMWTWNARVFPGIDPLPVRAGDRVRIRFGNLTMTNHPIHLHGYAFEV
CCCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCCEEEEEECCEEEECCCEEEEEEEEEE
AGTDGGWIAPAARWPEVTVDVAVGQMRAIEFTANRPGDWAFHCHKSHHTMNAMGHQVPNL
ECCCCCEECCCCCCCEEEEEEEECCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCC
IGVPQQDLAKRINKLVPDYMAMGSTGGAMGTMEMPLPENTLPMMTGTGPFGPLEMGGMFT
CCCCHHHHHHHHHHHCCHHHHCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCEEE
VVKVRQGLGRNDYRDPGWFRHPKGTVAYEYAGALPDD
EEEHHHCCCCCCCCCCCCEECCCCCEEEEECCCCCCC
>Mature Secondary Structure 
AKAATQPPLAPPNGRPYTPVVTLNGWTLPWRMKNGWKEFHLIAEPVVRELAPGMNAHLW
CCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEE
GYNGQTPGPTIEAVEGEKVRVFVTNRLPEHTTVHWHGMLLPCGMDGVGGLTQPHIPPGKT
CCCCCCCCCEEEEECCCEEEEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCE
FVYEFQLEKAGTFMYHPHADEMVQMAMGMMGTFIVHPKDRGAMPADRDFVFLMSAYDIDP
EEEEEEECCCCEEEECCCHHHHHHHHHHHHEEEEECCCCCCCCCCCCCEEEEEEEEECCC
GSFTPRVNEMTDFNMWTWNARVFPGIDPLPVRAGDRVRIRFGNLTMTNHPIHLHGYAFEV
CCCCCCCCCCCCCCEEEECCEECCCCCCCCCCCCCEEEEEECCEEEECCCEEEEEEEEEE
AGTDGGWIAPAARWPEVTVDVAVGQMRAIEFTANRPGDWAFHCHKSHHTMNAMGHQVPNL
ECCCCCEECCCCCCCEEEEEEEECCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHCCCC
IGVPQQDLAKRINKLVPDYMAMGSTGGAMGTMEMPLPENTLPMMTGTGPFGPLEMGGMFT
CCCCHHHHHHHHHHHCCHHHHCCCCCCCCEEEECCCCCCCCCEEECCCCCCCCCCCCEEE
VVKVRQGLGRNDYRDPGWFRHPKGTVAYEYAGALPDD
EEEHHHCCCCCCCCCCCCEECCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8594334 [H]