Click here to switch to the map view.

The map label for this gene is mocR [H]

Identifier: 76818684

GI number: 76818684

Start: 2215733

End: 2217427

Strand: Direct

Name: mocR [H]

Synonym: BURPS1710b_A1824

Alternate gene names: 76818684

Gene position: 2215733-2217427 (Clockwise)

Preceding gene: 76818494

Following gene: 76818014

Centisome position: 69.64

GC content: 73.39

Gene sequence:

>1695_bases
ATGCGGGTGAGCGTGCTGTCGGACTGGCTGGCGCAGCGGATCGTGCGCGGCGGCGGCGCGCAGCCGATCTACCGGCAATT
GCACCGGCTGCTGCAGCAGGCGATCCTGACCCGCGAACTGCCGGCGGGCGCGCGCGTGCCGTCGTCGCGGCTCCTCGCGG
CGGAGCTCGGGATCGCGCGCAACACCGTCACGCAGGTCTACGAGCAGCTTGCGCTCGAAGGCTACGTGAGCTCGGCGACC
GGGCGCGGCACGTTCGTCGCGGACAGCGCGCCCGACGAGATCGTCGGCGCGCCGGCGGATTCCCCGCCGGGGCTGCCGAG
GCCGGGGCTGCCGGGCACGCGCGGCGCGGCGGCGGGTGCCGAGGCGGCGGCCGGCATCGGATTCGACCCCACGCTCGAGC
CCGGCGCCGCGCGTCGTTCGCTGTCCGCGCGCGGCGCGCGCCTCGTCGGCGGCGCGGGCGTGTCGAAGCGGCAGGGCGGC
GCGTTCATGCCGGGCGTGCCCGACGTGTCGCGCTTTCCGGCGCGCGTGTGGACGCGGCTGCACAACAAGTACTGGCGGCG
GCTGCGCCCCGAGCTCTTGACCTACGCGCCGGGCGGCGGCCTCGCGCCGCTGCGCGAGGCGCTCGCCGATTACCTGCGCA
CGTCGCGTTCGGTGCGCTGCGCGCCCGAGCAGATCATCGTGACGACGGGCATTCATCAGTCGATCGATCTCGCGGTGCGC
CTGTTGACCGACCCGGGCGACGTGATCTGGACCGAGGATCCGTGCTACTGGGGCGTGCGCAGCGTGATGCACGTGTCGGG
CCTGACGACGCGGCCGATTCCCGTCGACGAAGAAGGGATCGCGCCCGCCGCCGCCGATTTCGCGGCGCCGCCGAAGCTGA
TGCTCGTCACGCCTTCGCACCAGTATCCGCTCGGCATGGTGATGAGCCTCGCGCGGCGGCGCATGCTGCTCGAATACGCG
CGCCAGCACGGCGCATGGATCATCGAGGACGATTACGACAGCGAATTCCGCTACGGCAGCCGCCCGCTCGCGTCGCTGCA
GGGGCTCGACACGGCCGGGCAGGTGATCTACGTCGGCAGCTTCAGCAAGACGCTGTTTCCGGGGCTGCGGGTCGGCTATC
TGGTCGCGCCCGAGCCGCTCGCCGAGAGCTTCGCGACCGCGAGCGCCGAGCTGTACCGCGAAGGGCAGCTCCTGCAGCAG
GCGGTGCTCGCCGAATTCATCGCGGAAGGGCATTTCGTGTCGCACATCCGCAAGATGCGCACGCTGTACGGGCAGCGCCG
GCAGACGCTGCTCGACGCGCTCGCGCGCCGTTACGGCGACGCGCTGCCGGCCGTCGGCGGCGATGCCGGGCTGCATCTCG
TGATGCGGCTGCCCGACGGCGCCGACGATCGCGCGCTCGCGCGCGCGGCGCTCGAACGCGATATCGTCGTGCGCGCGCTG
TCCGGCTATTACGCGCAGGCGACGCGCGCGGCGTCCGGGCTGCTGCTCGGCTATGCGTGCGTGCCGGAGGACGAGATCGG
GTGCGCGTTCGACGCGCTTTCGCGGGCGATCGACGACGTGGCGTTCGGGCGCGCCGCGGCGGCATCGTCGGCGCCGGCAT
CGACGTCGGCCGCGGCGGCATCGTCGGCATCGTCGGCATCGGCCGCGTCGACGACCTCGGCCGCCGCTCGAATGCCCGCC
GCCGTCGCGCGCTGA

Upstream 100 bases:

>100_bases
CCGCCGGCGGGCACGTCGTCCGGCGTGCGCGTCGAAACGACTATAATCAAACTTGGCTCTGAAAATCAGAGCCATTTTAA
TAAATATGTAGGAGCCAATT

Downstream 100 bases:

>100_bases
GCGGCCCGCGCGCCCGTCAGTAGCCGATCTGCACGGCGAACGCGAGCACGCCGCACGACAGCGCGAGCAGCACGGCGAAC
AGCGGCAGCACGAACCGCAG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MRVSVLSDWLAQRIVRGGGAQPIYRQLHRLLQQAILTRELPAGARVPSSRLLAAELGIARNTVTQVYEQLALEGYVSSAT
GRGTFVADSAPDEIVGAPADSPPGLPRPGLPGTRGAAAGAEAAAGIGFDPTLEPGAARRSLSARGARLVGGAGVSKRQGG
AFMPGVPDVSRFPARVWTRLHNKYWRRLRPELLTYAPGGGLAPLREALADYLRTSRSVRCAPEQIIVTTGIHQSIDLAVR
LLTDPGDVIWTEDPCYWGVRSVMHVSGLTTRPIPVDEEGIAPAAADFAAPPKLMLVTPSHQYPLGMVMSLARRRMLLEYA
RQHGAWIIEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGSFSKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQ
AVLAEFIAEGHFVSHIRKMRTLYGQRRQTLLDALARRYGDALPAVGGDAGLHLVMRLPDGADDRALARAALERDIVVRAL
SGYYAQATRAASGLLLGYACVPEDEIGCAFDALSRAIDDVAFGRAAAASSAPASTSAAAASSASSASAASTTSAAARMPA
AVAR

Sequences:

>Translated_564_residues
MRVSVLSDWLAQRIVRGGGAQPIYRQLHRLLQQAILTRELPAGARVPSSRLLAAELGIARNTVTQVYEQLALEGYVSSAT
GRGTFVADSAPDEIVGAPADSPPGLPRPGLPGTRGAAAGAEAAAGIGFDPTLEPGAARRSLSARGARLVGGAGVSKRQGG
AFMPGVPDVSRFPARVWTRLHNKYWRRLRPELLTYAPGGGLAPLREALADYLRTSRSVRCAPEQIIVTTGIHQSIDLAVR
LLTDPGDVIWTEDPCYWGVRSVMHVSGLTTRPIPVDEEGIAPAAADFAAPPKLMLVTPSHQYPLGMVMSLARRRMLLEYA
RQHGAWIIEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGSFSKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQ
AVLAEFIAEGHFVSHIRKMRTLYGQRRQTLLDALARRYGDALPAVGGDAGLHLVMRLPDGADDRALARAALERDIVVRAL
SGYYAQATRAASGLLLGYACVPEDEIGCAFDALSRAIDDVAFGRAAAASSAPASTSAAAASSASSASAASTTSAAARMPA
AVAR
>Mature_564_residues
MRVSVLSDWLAQRIVRGGGAQPIYRQLHRLLQQAILTRELPAGARVPSSRLLAAELGIARNTVTQVYEQLALEGYVSSAT
GRGTFVADSAPDEIVGAPADSPPGLPRPGLPGTRGAAAGAEAAAGIGFDPTLEPGAARRSLSARGARLVGGAGVSKRQGG
AFMPGVPDVSRFPARVWTRLHNKYWRRLRPELLTYAPGGGLAPLREALADYLRTSRSVRCAPEQIIVTTGIHQSIDLAVR
LLTDPGDVIWTEDPCYWGVRSVMHVSGLTTRPIPVDEEGIAPAAADFAAPPKLMLVTPSHQYPLGMVMSLARRRMLLEYA
RQHGAWIIEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGSFSKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQ
AVLAEFIAEGHFVSHIRKMRTLYGQRRQTLLDALARRYGDALPAVGGDAGLHLVMRLPDGADDRALARAALERDIVVRAL
SGYYAQATRAASGLLLGYACVPEDEIGCAFDALSRAIDDVAFGRAAAASSAPASTSAAAASSASSASAASTTSAAARMPA
AVAR

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=391, Percent_Identity=23.7851662404092, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI33469970, Length=391, Percent_Identity=23.7851662404092, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1790797, Length=484, Percent_Identity=29.3388429752066, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1787710, Length=468, Percent_Identity=24.5726495726496, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6321236, Length=337, Percent_Identity=23.1454005934718, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21356535, Length=330, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 59798; Mature: 59798

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVSVLSDWLAQRIVRGGGAQPIYRQLHRLLQQAILTRELPAGARVPSSRLLAAELGIAR
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NTVTQVYEQLALEGYVSSATGRGTFVADSAPDEIVGAPADSPPGLPRPGLPGTRGAAAGA
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
EAAAGIGFDPTLEPGAARRSLSARGARLVGGAGVSKRQGGAFMPGVPDVSRFPARVWTRL
HHHCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
HNKYWRRLRPELLTYAPGGGLAPLREALADYLRTSRSVRCAPEQIIVTTGIHQSIDLAVR
HHHHHHHHCHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHEEE
LLTDPGDVIWTEDPCYWGVRSVMHVSGLTTRPIPVDEEGIAPAAADFAAPPKLMLVTPSH
EECCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCC
QYPLGMVMSLARRRMLLEYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGS
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEEC
FSKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQAVLAEFIAEGHFVSHIRKMR
CHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TLYGQRRQTLLDALARRYGDALPAVGGDAGLHLVMRLPDGADDRALARAALERDIVVRAL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
SGYYAQATRAASGLLLGYACVPEDEIGCAFDALSRAIDDVAFGRAAAASSAPASTSAAAA
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SSASSASAASTTSAAARMPAAVAR
CCCCCCCHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MRVSVLSDWLAQRIVRGGGAQPIYRQLHRLLQQAILTRELPAGARVPSSRLLAAELGIAR
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NTVTQVYEQLALEGYVSSATGRGTFVADSAPDEIVGAPADSPPGLPRPGLPGTRGAAAGA
HHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
EAAAGIGFDPTLEPGAARRSLSARGARLVGGAGVSKRQGGAFMPGVPDVSRFPARVWTRL
HHHCCCCCCCCCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
HNKYWRRLRPELLTYAPGGGLAPLREALADYLRTSRSVRCAPEQIIVTTGIHQSIDLAVR
HHHHHHHHCHHHEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHEEE
LLTDPGDVIWTEDPCYWGVRSVMHVSGLTTRPIPVDEEGIAPAAADFAAPPKLMLVTPSH
EECCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCCC
QYPLGMVMSLARRRMLLEYARQHGAWIIEDDYDSEFRYGSRPLASLQGLDTAGQVIYVGS
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEEC
FSKTLFPGLRVGYLVAPEPLAESFATASAELYREGQLLQQAVLAEFIAEGHFVSHIRKMR
CHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TLYGQRRQTLLDALARRYGDALPAVGGDAGLHLVMRLPDGADDRALARAALERDIVVRAL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
SGYYAQATRAASGLLLGYACVPEDEIGCAFDALSRAIDDVAFGRAAAASSAPASTSAAAA
HHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
SSASSASAASTTSAAARMPAAVAR
CCCCCCCHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]