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The map label for this gene is tcp [H]

Identifier: 76818675

GI number: 76818675

Start: 2446654

End: 2448558

Strand: Direct

Name: tcp [H]

Synonym: BURPS1710b_A2013

Alternate gene names: 76818675

Gene position: 2446654-2448558 (Clockwise)

Preceding gene: 76819117

Following gene: 76818464

Centisome position: 76.9

GC content: 69.34

Gene sequence:

>1905_bases
GTGCTTCGCCCGGCCGTCACCCGATCCGTCGTTCCCACTGTTATCTGCGTTCGCATCATGAAACTTTTCTTCGACATGAA
GATCGGCACCCGGCTGATCGTGCTGATCCTCGCCGCGCTCGCCGCGCTATGCGCCATCGCCGGCTTCGGCATCTACGAGA
GCCGCCGCGTCTATACGGCCGCCAGCTATTCGACGGTCAACACCGTGCCGAGCTTCGTCGTGCTCGACGACGCGCAGCGC
GCGTTCGATTCCATGCTGCTGCTCGTGAACCAGCAGGTGTTCTCGACGACCGCGGATCAGGCGAAGGCGCTCGAGCCGAG
GATCGCGCAGGCGCGGCGGGAAGTCGACGCTCAGTTCGCGAAGTACGAAACGCTGCTGTCCAACGACAAGGACAAGGCGT
TGCTCGCGGCGGATCGCGCGCGGGTGAGCCAGCTCGACGCGGTGCGCGAGAACGTGCTCGCGCTGTCGCGCGACGGCAGG
AAGCAGGAGGCGGGCGAGCTGATGGGCACGCGGATGACCGAGCTCGCGCAGCAGACGAACGCGGCGCTCGCCGCGCATCG
CGCGTTCAACGTCGACCTCGGCCAGGCGGGCTCGAACGAAGCGAAGGACATCATCGATCGCGCGGTGACGCTCGAGGCGT
CGGCAGCCGCCGTCGTGCTGGTGCTCGTGTTGTGGCTCGGCGTGCTGATTTCGCGTTCGATCACGAAGCCGATGGGCAAC
GCGGTGAAGTTCGCGCGCACTGTTGCCGACGGCGATCTGACGACGCACATCGGCGCGGCGTCGAAGGACGAAACCGGGCA
GTTGCTCAAGGCGCTCGGCGACATGAACGACAGCCTGAAGCGCGTCGTCGAGCGCGTGCGCATGGGCAGCGACGCGGTGG
CGACCGCGTCTGGCCAGATCGCGGCCGGCAACCTCGATCTGTCCTCGCGCACCGAGGAACAGGCGGCGTCGCTGCAGGAG
ACCGCGGCGAGCATGGAGGAACTCACGTCGACGGTTCGGCAGAACGCGGAGAACGCGCAGCAGGCGAGCGGGCTCGCGTC
GAATGCGTCGGACGTCGCGCTGCGCGGCAGCTCCGTCGTCGATCGGGTGGTCGATACGATGAACGACATCAGCGAGCGTT
CGTCGAAGATCGCGGAGATCATCGGCATCATCGAAGGCATCGCGTTCCAGACCAACATCCTCGCGCTGAACGCGGCCGTC
GAGGCCGCGCGCGCGGGCGAGCAGGGCCGCGGCTTCGCGGTGGTCGCGGGCGAGGTGCGCGGGCTCGCGCAGCGCTCGTC
GAGCGCCGCGAAGGAGATCAAGGAACTGATCAGCGCCTCGGTGCAGAAGATTCGCGACGGCTCCGCGCTTGCCGGCGAAG
CGGGCCGGACGATGACCGAAGTCACGCAGGCGGTCGCGCGCGTGACCGACATCATGGGCGAGATCGCGGCGGCATCGGCC
GAGCAGAGCCGCGGCATCGAGCAGGTCAATCTCGCGATCACGCAGATGGACGAAGTCACGCAGCAGAACGCCGCGCTCGT
CGAGGAAGCGGCCGCCGCCTCGCATTCGCTCGAAGAGCAGGGGCACGAACTGAAGCAGGCTGTCGCGTTCTTCCGGTTCG
ACGGCAGCGCCGCCGGTGGGACGGCGGATACGGCCGCGCCCCGGCATCGGGCCGCGCCGCCGCCGCACGCGGCGGCGACG
GCACCGGCGGCGCATGCGACCCCCGCACCCCATGCACCCCACGCGTCCCACGCGTCCCACGCGATACGTACGGCGCACGC
AACGCCTGCGCCGCGCGCGTTCGACGCCGTGAAGCCGGCCGCGTCCGCGGCGCCCGCCGCGGCTGCCGTGTCCGCGCCCG
CGCCCGCGTTTTCAAGCGCGCGTGCGACGGCGGCGGATGCGAACGCGGATTGGGAAACGTTCTGA

Upstream 100 bases:

>100_bases
AACGGTGTCGGATGGCAATACGAAGTTTTCTCGTTCGAGCCCTGCAGATGCATGACGGAGGCGCGATCAATTCTCATACG
ATTGGCCTGCGGCATCGAAC

Downstream 100 bases:

>100_bases
ACGCGGGACGATGACACGCGCGCGGCACGCCTCGCCCGCGCCTGCCTCGCGCGCGCCGCTGGGTGAAGGTCTTCGTTGCG
TCGGGCGCCGGGTCGCATGT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MLRPAVTRSVVPTVICVRIMKLFFDMKIGTRLIVLILAALAALCAIAGFGIYESRRVYTAASYSTVNTVPSFVVLDDAQR
AFDSMLLLVNQQVFSTTADQAKALEPRIAQARREVDAQFAKYETLLSNDKDKALLAADRARVSQLDAVRENVLALSRDGR
KQEAGELMGTRMTELAQQTNAALAAHRAFNVDLGQAGSNEAKDIIDRAVTLEASAAAVVLVLVLWLGVLISRSITKPMGN
AVKFARTVADGDLTTHIGAASKDETGQLLKALGDMNDSLKRVVERVRMGSDAVATASGQIAAGNLDLSSRTEEQAASLQE
TAASMEELTSTVRQNAENAQQASGLASNASDVALRGSSVVDRVVDTMNDISERSSKIAEIIGIIEGIAFQTNILALNAAV
EAARAGEQGRGFAVVAGEVRGLAQRSSSAAKEIKELISASVQKIRDGSALAGEAGRTMTEVTQAVARVTDIMGEIAAASA
EQSRGIEQVNLAITQMDEVTQQNAALVEEAAAASHSLEEQGHELKQAVAFFRFDGSAAGGTADTAAPRHRAAPPPHAAAT
APAAHATPAPHAPHASHASHAIRTAHATPAPRAFDAVKPAASAAPAAAAVSAPAPAFSSARATAADANADWETF

Sequences:

>Translated_634_residues
MLRPAVTRSVVPTVICVRIMKLFFDMKIGTRLIVLILAALAALCAIAGFGIYESRRVYTAASYSTVNTVPSFVVLDDAQR
AFDSMLLLVNQQVFSTTADQAKALEPRIAQARREVDAQFAKYETLLSNDKDKALLAADRARVSQLDAVRENVLALSRDGR
KQEAGELMGTRMTELAQQTNAALAAHRAFNVDLGQAGSNEAKDIIDRAVTLEASAAAVVLVLVLWLGVLISRSITKPMGN
AVKFARTVADGDLTTHIGAASKDETGQLLKALGDMNDSLKRVVERVRMGSDAVATASGQIAAGNLDLSSRTEEQAASLQE
TAASMEELTSTVRQNAENAQQASGLASNASDVALRGSSVVDRVVDTMNDISERSSKIAEIIGIIEGIAFQTNILALNAAV
EAARAGEQGRGFAVVAGEVRGLAQRSSSAAKEIKELISASVQKIRDGSALAGEAGRTMTEVTQAVARVTDIMGEIAAASA
EQSRGIEQVNLAITQMDEVTQQNAALVEEAAAASHSLEEQGHELKQAVAFFRFDGSAAGGTADTAAPRHRAAPPPHAAAT
APAAHATPAPHAPHASHASHAIRTAHATPAPRAFDAVKPAASAAPAAAAVSAPAPAFSSARATAADANADWETF
>Mature_634_residues
MLRPAVTRSVVPTVICVRIMKLFFDMKIGTRLIVLILAALAALCAIAGFGIYESRRVYTAASYSTVNTVPSFVVLDDAQR
AFDSMLLLVNQQVFSTTADQAKALEPRIAQARREVDAQFAKYETLLSNDKDKALLAADRARVSQLDAVRENVLALSRDGR
KQEAGELMGTRMTELAQQTNAALAAHRAFNVDLGQAGSNEAKDIIDRAVTLEASAAAVVLVLVLWLGVLISRSITKPMGN
AVKFARTVADGDLTTHIGAASKDETGQLLKALGDMNDSLKRVVERVRMGSDAVATASGQIAAGNLDLSSRTEEQAASLQE
TAASMEELTSTVRQNAENAQQASGLASNASDVALRGSSVVDRVVDTMNDISERSSKIAEIIGIIEGIAFQTNILALNAAV
EAARAGEQGRGFAVVAGEVRGLAQRSSSAAKEIKELISASVQKIRDGSALAGEAGRTMTEVTQAVARVTDIMGEIAAASA
EQSRGIEQVNLAITQMDEVTQQNAALVEEAAAASHSLEEQGHELKQAVAFFRFDGSAAGGTADTAAPRHRAAPPPHAAAT
APAAHATPAPHAPHASHASHAIRTAHATPAPRAFDAVKPAASAAPAAAAVSAPAPAFSSARATAADANADWETF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=337, Percent_Identity=59.6439169139466, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI1788195, Length=330, Percent_Identity=56.3636363636364, Blast_Score=319, Evalue=4e-88,
Organism=Escherichia coli, GI1787690, Length=339, Percent_Identity=53.3923303834808, Blast_Score=301, Evalue=8e-83,
Organism=Escherichia coli, GI1788194, Length=319, Percent_Identity=52.3510971786834, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1789453, Length=330, Percent_Identity=37.5757575757576, Blast_Score=202, Evalue=7e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 66189; Mature: 66189

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPAVTRSVVPTVICVRIMKLFFDMKIGTRLIVLILAALAALCAIAGFGIYESRRVYTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ASYSTVNTVPSFVVLDDAQRAFDSMLLLVNQQVFSTTADQAKALEPRIAQARREVDAQFA
ECCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KYETLLSNDKDKALLAADRARVSQLDAVRENVLALSRDGRKQEAGELMGTRMTELAQQTN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AALAAHRAFNVDLGQAGSNEAKDIIDRAVTLEASAAAVVLVLVLWLGVLISRSITKPMGN
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVKFARTVADGDLTTHIGAASKDETGQLLKALGDMNDSLKRVVERVRMGSDAVATASGQI
HHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHEECCCCE
AAGNLDLSSRTEEQAASLQETAASMEELTSTVRQNAENAQQASGLASNASDVALRGSSVV
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEECCHHHH
DRVVDTMNDISERSSKIAEIIGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
GLAQRSSSAAKEIKELISASVQKIRDGSALAGEAGRTMTEVTQAVARVTDIMGEIAAASA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EQSRGIEQVNLAITQMDEVTQQNAALVEEAAAASHSLEEQGHELKQAVAFFRFDGSAAGG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TADTAAPRHRAAPPPHAAATAPAAHATPAPHAPHASHASHAIRTAHATPAPRAFDAVKPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCH
ASAAPAAAAVSAPAPAFSSARATAADANADWETF
HHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRPAVTRSVVPTVICVRIMKLFFDMKIGTRLIVLILAALAALCAIAGFGIYESRRVYTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ASYSTVNTVPSFVVLDDAQRAFDSMLLLVNQQVFSTTADQAKALEPRIAQARREVDAQFA
ECCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KYETLLSNDKDKALLAADRARVSQLDAVRENVLALSRDGRKQEAGELMGTRMTELAQQTN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AALAAHRAFNVDLGQAGSNEAKDIIDRAVTLEASAAAVVLVLVLWLGVLISRSITKPMGN
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVKFARTVADGDLTTHIGAASKDETGQLLKALGDMNDSLKRVVERVRMGSDAVATASGQI
HHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHEECCCCE
AAGNLDLSSRTEEQAASLQETAASMEELTSTVRQNAENAQQASGLASNASDVALRGSSVV
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEECCHHHH
DRVVDTMNDISERSSKIAEIIGIIEGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
GLAQRSSSAAKEIKELISASVQKIRDGSALAGEAGRTMTEVTQAVARVTDIMGEIAAASA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EQSRGIEQVNLAITQMDEVTQQNAALVEEAAAASHSLEEQGHELKQAVAFFRFDGSAAGG
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TADTAAPRHRAAPPPHAAATAPAAHATPAPHAPHASHASHAIRTAHATPAPRAFDAVKPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCH
ASAAPAAAAVSAPAPAFSSARATAADANADWETF
HHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]