Click here to switch to the map view.

The map label for this gene is fadD21 [H]

Identifier: 76818257

GI number: 76818257

Start: 2478681

End: 2482511

Strand: Direct

Name: fadD21 [H]

Synonym: BURPS1710b_A2039

Alternate gene names: 76818257

Gene position: 2478681-2482511 (Clockwise)

Preceding gene: 76817525

Following gene: 76818244

Centisome position: 77.9

GC content: 70.82

Gene sequence:

>3831_bases
GTGCGCGCGGCGACGCGCGGCGAGAAAGTCGCGTATCTGTTCCTGAGCGGTCAGCCCGACGACGAACAGCGGCAATCGAT
CACGTTCGCCGAGCTCGACCGAACCGCGCGCCGCGTCGCGCTGCTGCTGCAACGGCAATCGGTCGGCGTCGGCGAGCGCG
TGCTGCTGCTGTGCCGGCCGGGTCTCGACTACATCGCGGGCTTTCTCGGCTGCCTGTATGCGGGCGCGGTCGCCGTGCCC
GCGTATCCGCCGCGCAACCGGCAGCACGCGAGCCGCGTCGTCGGCATCGTCGAGAGCGCGGGTGCGAAGGCGATCCTGTC
CACCGGCGACGATTTCGCGCGCTGCACGAAACTGCTGGAGGATACGGCGGCCTCGCACGTCGCGCTGCTCGATCTCGACG
CCGCGAAGCCGCTTGACGCGACGCTCGAGCCGGCCGATGTCGCGCCTTCGCACGTCGCGTTCCTGCAGTACACATCGGGT
ACCACCGGCAAGCCGAAGGGCGTGATGGTCACCCATGGCAACCTGATCCACAACCTCGCGCTGATCGGCCAATGGATGGG
GTATCACGAAGAAAGCACGATGGTCAGCTGGCTGCCGCCGTATCACGACATGGGGCTGATCGGCGGAATCCTGACATCGC
TGTTCGGCGGCTTCCGGTGCGTGCTGATGGCGCCGGAGCGCTTCATCCAGCATCCGTTCCTGTGGCTGCGCGCGATCAGC
GACTATCGCGCCGACGTGACGGGCGCGCCCGATTTCGCTTACCGGATGTGCAGCCGCCGCGTGCCCGACGAACAACTCGC
GACGCTCGACCTGAGCTGCCTGAAGACCGCGTACAGCGGCGCGGAATCGGTCCGCTACGGCACGCTCGCGGAATTCGCGC
AGCGCTTCGCGCGCACGGGCTTCGATTCCGAGCGCTTCAAGCCGTGCTACGGTCTTGCCGAATGCACGCTGCTCGTCGCG
GGGCGCAGCGCGCCGCGGCCGCTGCGCACGGTGTGCGTCGATCAGGCGGCGCTGCAGCAGCAGAAGGTCGTGATCCGGCG
CGCGTTCGAGGGGCTCGCGCCGCAACTGGACGAACGCGACGGCGAGCGCGTGCTCGTGAGCGTCGGCGTGACGATCGGCG
AGCAGCGGGTGGTCGTGCGCGACCTGAATACGAACGAGCGCTGCGCGGACGGCGAAATCGGCGAGATCTGCGTGGCGGGC
CCGAGCGTCGCGCCCGGCTACTGGCAGCAGTACGAACAGACGCTCGCGACGTTCCAGCGCGGCATCGGCGGCGAGACCGG
GCAGGCATTCGCCGGCACGGGCGACCTCGGCTTCCACCACCGCGGCGACCTGTACGTGACCGGCCGCCTGAAGGACATGA
TCATCATCGCGGGGCGCAACTACTACTCGGAGGATATCGAGTACGCGGTGATCGGCAGTCGGCCCGAACTGGTGCCGAAC
GGCTGCGCGGCATTCACCGTCGACGCGGGCGACGAGGAGCGGCTCGTCGTCGTCGCGGAGATCGAGCGCACGCATCGCAA
GGGCGATCTCGACGCGCTGCTCAAGGGCATTCGCGAAGCGATCTGGCTGCGCCACGACCTGAGCCCGGGCGCGGTGCTGC
TGGTGTCGCCCGGCAGCGTGCCGAAGACGTCGAGCGGCAAGGTGCGGCGCGGCGAATGCCGCAAGCGGCTGGGCGACGGC
GAGCTGACGGTGCTCGCGCGCTGGGACGCGGACGACTGCATCGCCGCGGCCACGCGAGGCGACACCGCGGCGAATGCGCC
GTCGAATGTGCCGTCGAGTGCGCCGGCATCGGCGGCGGCGACGGCACCGGCGGCGCCGGCCGAAAAAACGCCGGCGGCCG
ACGCGGCCGGCGCCGCTTCGCCGAACGCCGCGAAAGTCGAGCAGCTCAAGGACTGGCTGCGCCACTACGCGCGCACGCGG
ATCGATTCGCGAACCATCGACGAGCGCCGCACCATCCCGCCGCACATCGTGCTCGATTTCGGCAACGAAGGGTTGCTCGG
CATGCAGATCGATCGCGCGTACGGCGGCCTCGGCCTCACGAACCGCGAAATGCTGCAGGTGGTGTCGCAACTGGCCACGA
TCGATTCGACGCTCGCCTTCTTCGTCGGCCTGAACAATACGCTCGGCATCCGGCCGATCATGCTGCACGCGCAGCCCGCG
CTGCGCGACGAGCTGCTGCCGCTGCTCGCGACGGGCCGCACGCTCGCCGCGTTCGCGCTGACCGAGCCGGACGCGGGCTC
GAACGCGCGCGCGATCGCTTCGGTCGCGCAGCGCGCCGACGGCGGCCATTGGGTGGTTAGCGGCCGCAAGAGCTGGAGCG
GATCGTCGGCGTGGGCGGGCGTGATCAACGTGTTCGCGAAGCAGGCGGACGGCGCGGGCATGGTCGGGCTCGCGCTGCGG
CAGGGTACGCCCGGCCTGCGGATCGGCGCGGAAGACCTGACGATGGGCGTGCGCGGGATGATCCAGAACACGCTGCATCT
CGAGCGCGCGCGCGTGAGCGATGCATGCCGGCTCGGCGCGCCGGGGCAGGGGATGGCGGTCGCGCAGCAGACGATGAACT
TCGCGCGCCTCGGCATCGGCGCGGTGTGCGTCGGCGCGATGAAGCGCTGCGCGCAGCTGATGCATCGCTATGCGGCGCGC
CGCCGGATCGGCACCGGCCTGCTGCTCGACCATCCGCTGAGCCGCCAGCGTCTCGGCGACCTGCGGCACCGGATCGACGC
ACTGAGCGCGTTGATCGAGCAACTGGCGGCCGATTTCGACGCGGGGCGCGACGCGCCCGAAGACGGCCTGCTGATCGCGA
AGATACTCGGCTCGGAGTGCCTGTCGCAAACGTCCGACGAACTGATGCAGATGCTGGGCGGCCGCGGCTACATCGAGACG
AACGTCGCGCCGCAGCTCTTCCGCGATGCGCGGCTGCCGCGCATCTTCGAGGGGCCGACCGAGACGCTGCTCGCGCATCT
GGGCAGCCGCCTGCTGAACGGCGGCGACGATCTGCTCGGCTATCTCGGCGAGCGTTCGGGCGCGCTCGCGTTGGCCGCCG
AACTGCGCGGGCTCGGCGAGCAACTGCTCGAGGACGGCCTGGCGAACGCGGACGCGCTCGGCGGCGCCGCGCACGCGGCG
AACTGGGTCAACTACTGGCTCGGCAGCGTCGCGCAATGGGCGCTGCTGCTCGCCGTCGTCGAGCAGGCCGCGAAGCGGCG
CGGCGTCGACGGCGCGACGCTCGAATGGGCGCAGAGCCAGTACGAGCTCGCGCTCGAGGCGGCGCAACGCCAGGTGGGCC
GCCGGCGCGTGCTCGCGAGCGCCGCGCAGCTCGGCGAGTGGGCACAGCGGGTCGAGCGCGAGATCGGCCCGATCGAGCAG
ACGGTGCCGGGCGCGACGCAACGGGTCGATCCGCTGCTGCGGGCCGAATGCGATGTGCGTTCGCAGCCGTCCGACATCGG
CGCGCTGGACGACGACGAGCCGCCTGCCGCCGGCGTGCCGCCCGCGCCCGTGCCTTCGCCCGCGTCCGCGTCCGCCGAGC
AGGCCGATCCCGAACTGAAGCGCGAGGTCGAGCGCTGGCTGCTGACGTGGCTCGGCGCGCGCCTGCGCAATCGCCGGATC
GCGCTGACGGCCGAGACGACGTTCGCCGACATCGGCCTCGATTCGATTCTCGCCGTCGAGCTGACGATGGCGTTCGGCGA
CGCGTTTCGCACGACCGTCGACGCGTCGGCCGTCTGGGACCACGCGTCGATCGACGCATTGGCGACGCATCTCGCCGCCC
GAATGGACCGGCACGCGCCCGCGCAAGCGGACGCAGCTTCGTCCGCCCCTTCTGCTTCTTCTTCCTTGTGA

Upstream 100 bases:

>100_bases
GGCCGCCGAACGCAACCACCACGATCGTGGGTTTCATTTCCTGTCGGATGACGTCATGACCACCACCAATCTGCCGAAGA
CGATCAACGAGCTGCTGCGC

Downstream 100 bases:

>100_bases
GGCGCATCCGATCATGCAGTCGCTTTGTGAACTTGCCACATCCGCCGGCGCCCTGGGCGCACAGCTCGAAAACTATCTCC
GCTCGCATGCCGACGACAGC

Product: polyketide synthase

Products: AMP; diphosphate +an acyl-CoA [C]

Alternate protein names: Acyl-CoA synthetase [H]

Number of amino acids: Translated: 1276; Mature: 1276

Protein sequence:

>1276_residues
MRAATRGEKVAYLFLSGQPDDEQRQSITFAELDRTARRVALLLQRQSVGVGERVLLLCRPGLDYIAGFLGCLYAGAVAVP
AYPPRNRQHASRVVGIVESAGAKAILSTGDDFARCTKLLEDTAASHVALLDLDAAKPLDATLEPADVAPSHVAFLQYTSG
TTGKPKGVMVTHGNLIHNLALIGQWMGYHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCVLMAPERFIQHPFLWLRAIS
DYRADVTGAPDFAYRMCSRRVPDEQLATLDLSCLKTAYSGAESVRYGTLAEFAQRFARTGFDSERFKPCYGLAECTLLVA
GRSAPRPLRTVCVDQAALQQQKVVIRRAFEGLAPQLDERDGERVLVSVGVTIGEQRVVVRDLNTNERCADGEIGEICVAG
PSVAPGYWQQYEQTLATFQRGIGGETGQAFAGTGDLGFHHRGDLYVTGRLKDMIIIAGRNYYSEDIEYAVIGSRPELVPN
GCAAFTVDAGDEERLVVVAEIERTHRKGDLDALLKGIREAIWLRHDLSPGAVLLVSPGSVPKTSSGKVRRGECRKRLGDG
ELTVLARWDADDCIAAATRGDTAANAPSNVPSSAPASAAATAPAAPAEKTPAADAAGAASPNAAKVEQLKDWLRHYARTR
IDSRTIDERRTIPPHIVLDFGNEGLLGMQIDRAYGGLGLTNREMLQVVSQLATIDSTLAFFVGLNNTLGIRPIMLHAQPA
LRDELLPLLATGRTLAAFALTEPDAGSNARAIASVAQRADGGHWVVSGRKSWSGSSAWAGVINVFAKQADGAGMVGLALR
QGTPGLRIGAEDLTMGVRGMIQNTLHLERARVSDACRLGAPGQGMAVAQQTMNFARLGIGAVCVGAMKRCAQLMHRYAAR
RRIGTGLLLDHPLSRQRLGDLRHRIDALSALIEQLAADFDAGRDAPEDGLLIAKILGSECLSQTSDELMQMLGGRGYIET
NVAPQLFRDARLPRIFEGPTETLLAHLGSRLLNGGDDLLGYLGERSGALALAAELRGLGEQLLEDGLANADALGGAAHAA
NWVNYWLGSVAQWALLLAVVEQAAKRRGVDGATLEWAQSQYELALEAAQRQVGRRRVLASAAQLGEWAQRVEREIGPIEQ
TVPGATQRVDPLLRAECDVRSQPSDIGALDDDEPPAAGVPPAPVPSPASASAEQADPELKREVERWLLTWLGARLRNRRI
ALTAETTFADIGLDSILAVELTMAFGDAFRTTVDASAVWDHASIDALATHLAARMDRHAPAQADAASSAPSASSSL

Sequences:

>Translated_1276_residues
MRAATRGEKVAYLFLSGQPDDEQRQSITFAELDRTARRVALLLQRQSVGVGERVLLLCRPGLDYIAGFLGCLYAGAVAVP
AYPPRNRQHASRVVGIVESAGAKAILSTGDDFARCTKLLEDTAASHVALLDLDAAKPLDATLEPADVAPSHVAFLQYTSG
TTGKPKGVMVTHGNLIHNLALIGQWMGYHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCVLMAPERFIQHPFLWLRAIS
DYRADVTGAPDFAYRMCSRRVPDEQLATLDLSCLKTAYSGAESVRYGTLAEFAQRFARTGFDSERFKPCYGLAECTLLVA
GRSAPRPLRTVCVDQAALQQQKVVIRRAFEGLAPQLDERDGERVLVSVGVTIGEQRVVVRDLNTNERCADGEIGEICVAG
PSVAPGYWQQYEQTLATFQRGIGGETGQAFAGTGDLGFHHRGDLYVTGRLKDMIIIAGRNYYSEDIEYAVIGSRPELVPN
GCAAFTVDAGDEERLVVVAEIERTHRKGDLDALLKGIREAIWLRHDLSPGAVLLVSPGSVPKTSSGKVRRGECRKRLGDG
ELTVLARWDADDCIAAATRGDTAANAPSNVPSSAPASAAATAPAAPAEKTPAADAAGAASPNAAKVEQLKDWLRHYARTR
IDSRTIDERRTIPPHIVLDFGNEGLLGMQIDRAYGGLGLTNREMLQVVSQLATIDSTLAFFVGLNNTLGIRPIMLHAQPA
LRDELLPLLATGRTLAAFALTEPDAGSNARAIASVAQRADGGHWVVSGRKSWSGSSAWAGVINVFAKQADGAGMVGLALR
QGTPGLRIGAEDLTMGVRGMIQNTLHLERARVSDACRLGAPGQGMAVAQQTMNFARLGIGAVCVGAMKRCAQLMHRYAAR
RRIGTGLLLDHPLSRQRLGDLRHRIDALSALIEQLAADFDAGRDAPEDGLLIAKILGSECLSQTSDELMQMLGGRGYIET
NVAPQLFRDARLPRIFEGPTETLLAHLGSRLLNGGDDLLGYLGERSGALALAAELRGLGEQLLEDGLANADALGGAAHAA
NWVNYWLGSVAQWALLLAVVEQAAKRRGVDGATLEWAQSQYELALEAAQRQVGRRRVLASAAQLGEWAQRVEREIGPIEQ
TVPGATQRVDPLLRAECDVRSQPSDIGALDDDEPPAAGVPPAPVPSPASASAEQADPELKREVERWLLTWLGARLRNRRI
ALTAETTFADIGLDSILAVELTMAFGDAFRTTVDASAVWDHASIDALATHLAARMDRHAPAQADAASSAPSASSSL
>Mature_1276_residues
MRAATRGEKVAYLFLSGQPDDEQRQSITFAELDRTARRVALLLQRQSVGVGERVLLLCRPGLDYIAGFLGCLYAGAVAVP
AYPPRNRQHASRVVGIVESAGAKAILSTGDDFARCTKLLEDTAASHVALLDLDAAKPLDATLEPADVAPSHVAFLQYTSG
TTGKPKGVMVTHGNLIHNLALIGQWMGYHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCVLMAPERFIQHPFLWLRAIS
DYRADVTGAPDFAYRMCSRRVPDEQLATLDLSCLKTAYSGAESVRYGTLAEFAQRFARTGFDSERFKPCYGLAECTLLVA
GRSAPRPLRTVCVDQAALQQQKVVIRRAFEGLAPQLDERDGERVLVSVGVTIGEQRVVVRDLNTNERCADGEIGEICVAG
PSVAPGYWQQYEQTLATFQRGIGGETGQAFAGTGDLGFHHRGDLYVTGRLKDMIIIAGRNYYSEDIEYAVIGSRPELVPN
GCAAFTVDAGDEERLVVVAEIERTHRKGDLDALLKGIREAIWLRHDLSPGAVLLVSPGSVPKTSSGKVRRGECRKRLGDG
ELTVLARWDADDCIAAATRGDTAANAPSNVPSSAPASAAATAPAAPAEKTPAADAAGAASPNAAKVEQLKDWLRHYARTR
IDSRTIDERRTIPPHIVLDFGNEGLLGMQIDRAYGGLGLTNREMLQVVSQLATIDSTLAFFVGLNNTLGIRPIMLHAQPA
LRDELLPLLATGRTLAAFALTEPDAGSNARAIASVAQRADGGHWVVSGRKSWSGSSAWAGVINVFAKQADGAGMVGLALR
QGTPGLRIGAEDLTMGVRGMIQNTLHLERARVSDACRLGAPGQGMAVAQQTMNFARLGIGAVCVGAMKRCAQLMHRYAAR
RRIGTGLLLDHPLSRQRLGDLRHRIDALSALIEQLAADFDAGRDAPEDGLLIAKILGSECLSQTSDELMQMLGGRGYIET
NVAPQLFRDARLPRIFEGPTETLLAHLGSRLLNGGDDLLGYLGERSGALALAAELRGLGEQLLEDGLANADALGGAAHAA
NWVNYWLGSVAQWALLLAVVEQAAKRRGVDGATLEWAQSQYELALEAAQRQVGRRRVLASAAQLGEWAQRVEREIGPIEQ
TVPGATQRVDPLLRAECDVRSQPSDIGALDDDEPPAAGVPPAPVPSPASASAEQADPELKREVERWLLTWLGARLRNRRI
ALTAETTFADIGLDSILAVELTMAFGDAFRTTVDASAVWDHASIDALATHLAARMDRHAPAQADAASSAPSASSSL

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=373, Percent_Identity=27.0777479892761, Blast_Score=154, Evalue=4e-37,
Organism=Homo sapiens, GI225735629, Length=548, Percent_Identity=27.7372262773723, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI45827692, Length=548, Percent_Identity=27.7372262773723, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=27.1739130434783, Blast_Score=141, Evalue=3e-33,
Organism=Homo sapiens, GI4557235, Length=388, Percent_Identity=27.8350515463918, Blast_Score=139, Evalue=3e-32,
Organism=Homo sapiens, GI76496475, Length=388, Percent_Identity=27.8350515463918, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI44888818, Length=583, Percent_Identity=26.9296740994854, Blast_Score=138, Evalue=4e-32,
Organism=Homo sapiens, GI4557233, Length=359, Percent_Identity=27.5766016713092, Blast_Score=134, Evalue=5e-31,
Organism=Homo sapiens, GI55749758, Length=503, Percent_Identity=28.4294234592445, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=25.4545454545455, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI226958412, Length=330, Percent_Identity=25.4545454545455, Blast_Score=110, Evalue=1e-23,
Organism=Homo sapiens, GI225735625, Length=553, Percent_Identity=26.4014466546112, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI7656849, Length=349, Percent_Identity=23.7822349570201, Blast_Score=105, Evalue=3e-22,
Organism=Homo sapiens, GI187960098, Length=324, Percent_Identity=25, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI4557231, Length=324, Percent_Identity=25, Blast_Score=102, Evalue=3e-21,
Organism=Homo sapiens, GI45827694, Length=491, Percent_Identity=27.0875763747454, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI225735627, Length=464, Percent_Identity=26.5086206896552, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI45827696, Length=464, Percent_Identity=26.5086206896552, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI4501857, Length=328, Percent_Identity=22.8658536585366, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI187761345, Length=588, Percent_Identity=22.9591836734694, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI187761343, Length=588, Percent_Identity=22.9591836734694, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI7669494, Length=337, Percent_Identity=27.299703264095, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI4503943, Length=337, Percent_Identity=27.299703264095, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI45827698, Length=426, Percent_Identity=27.4647887323944, Blast_Score=77, Evalue=1e-13,
Organism=Escherichia coli, GI87081702, Length=373, Percent_Identity=25.201072386059, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=345, Percent_Identity=30.7246376811594, Blast_Score=167, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=369, Percent_Identity=27.10027100271, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71985192, Length=284, Percent_Identity=30.6338028169014, Blast_Score=140, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI17508101, Length=350, Percent_Identity=26, Blast_Score=131, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI193202679, Length=620, Percent_Identity=23.3870967741935, Blast_Score=127, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17570075, Length=360, Percent_Identity=26.3888888888889, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17569725, Length=359, Percent_Identity=25.6267409470752, Blast_Score=120, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=27.3722627737226, Blast_Score=111, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17538396, Length=331, Percent_Identity=25.6797583081571, Blast_Score=108, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17533517, Length=353, Percent_Identity=24.929178470255, Blast_Score=107, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=220, Percent_Identity=30.4545454545455, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=357, Percent_Identity=24.6498599439776, Blast_Score=103, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17558820, Length=457, Percent_Identity=24.2888402625821, Blast_Score=97, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=308, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=553, Percent_Identity=23.1464737793852, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994690, Length=418, Percent_Identity=25.3588516746411, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994694, Length=418, Percent_Identity=25.3588516746411, Blast_Score=87, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994703, Length=418, Percent_Identity=25.3588516746411, Blast_Score=87, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=273, Percent_Identity=24.9084249084249, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=343, Percent_Identity=25.0728862973761, Blast_Score=77, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=340, Percent_Identity=24.4117647058824, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363737, Length=329, Percent_Identity=29.483282674772, Blast_Score=151, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21356377, Length=360, Percent_Identity=25.5555555555556, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24666513, Length=406, Percent_Identity=27.3399014778325, Blast_Score=124, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24654656, Length=489, Percent_Identity=25.5623721881391, Blast_Score=124, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24646207, Length=358, Percent_Identity=27.9329608938547, Blast_Score=122, Evalue=2e-27,
Organism=Drosophila melanogaster, GI21355753, Length=339, Percent_Identity=24.7787610619469, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24660351, Length=364, Percent_Identity=26.0989010989011, Blast_Score=98, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19920834, Length=306, Percent_Identity=24.5098039215686, Blast_Score=74, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: 6.2.1.3 [C]

Molecular weight: Translated: 136757; Mature: 136757

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAATRGEKVAYLFLSGQPDDEQRQSITFAELDRTARRVALLLQRQSVGVGERVLLLCRP
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
GLDYIAGFLGCLYAGAVAVPAYPPRNRQHASRVVGIVESAGAKAILSTGDDFARCTKLLE
CHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHH
DTAASHVALLDLDAAKPLDATLEPADVAPSHVAFLQYTSGTTGKPKGVMVTHGNLIHNLA
HHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHH
LIGQWMGYHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCVLMAPERFIQHPFLWLRAIS
HHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCHHHHHHHHH
DYRADVTGAPDFAYRMCSRRVPDEQLATLDLSCLKTAYSGAESVRYGTLAEFAQRFARTG
HHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCC
FDSERFKPCYGLAECTLLVAGRSAPRPLRTVCVDQAALQQQKVVIRRAFEGLAPQLDERD
CCHHHCCCCCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GERVLVSVGVTIGEQRVVVRDLNTNERCADGEIGEICVAGPSVAPGYWQQYEQTLATFQR
CCEEEEEECCEECCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
GIGGETGQAFAGTGDLGFHHRGDLYVTGRLKDMIIIAGRNYYSEDIEYAVIGSRPELVPN
CCCCCCCCCEECCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCEEEECCCCCCCCC
GCAAFTVDAGDEERLVVVAEIERTHRKGDLDALLKGIREAIWLRHDLSPGAVLLVSPGSV
CCEEEEECCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
PKTSSGKVRRGECRKRLGDGELTVLARWDADDCIAAATRGDTAANAPSNVPSSAPASAAA
CCCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
TAPAAPAEKTPAADAAGAASPNAAKVEQLKDWLRHYARTRIDSRTIDERRTIPPHIVLDF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCHHCCCCCCEEEEEC
GNEGLLGMQIDRAYGGLGLTNREMLQVVSQLATIDSTLAFFVGLNNTLGIRPIMLHAQPA
CCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHH
LRDELLPLLATGRTLAAFALTEPDAGSNARAIASVAQRADGGHWVVSGRKSWSGSSAWAG
HHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
VINVFAKQADGAGMVGLALRQGTPGLRIGAEDLTMGVRGMIQNTLHLERARVSDACRLGA
HHHHHHHCCCCCCEEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGQGMAVAQQTMNFARLGIGAVCVGAMKRCAQLMHRYAARRRIGTGLLLDHPLSRQRLGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHH
LRHRIDALSALIEQLAADFDAGRDAPEDGLLIAKILGSECLSQTSDELMQMLGGRGYIET
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NVAPQLFRDARLPRIFEGPTETLLAHLGSRLLNGGDDLLGYLGERSGALALAAELRGLGE
CCCHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHH
QLLEDGLANADALGGAAHAANWVNYWLGSVAQWALLLAVVEQAAKRRGVDGATLEWAQSQ
HHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
YELALEAAQRQVGRRRVLASAAQLGEWAQRVEREIGPIEQTVPGATQRVDPLLRAECDVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHCHHHHCCCCCC
SQPSDIGALDDDEPPAAGVPPAPVPSPASASAEQADPELKREVERWLLTWLGARLRNRRI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCEE
ALTAETTFADIGLDSILAVELTMAFGDAFRTTVDASAVWDHASIDALATHLAARMDRHAP
EEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCC
AQADAASSAPSASSSL
CCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRAATRGEKVAYLFLSGQPDDEQRQSITFAELDRTARRVALLLQRQSVGVGERVLLLCRP
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECC
GLDYIAGFLGCLYAGAVAVPAYPPRNRQHASRVVGIVESAGAKAILSTGDDFARCTKLLE
CHHHHHHHHHHHHHCCEECCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHH
DTAASHVALLDLDAAKPLDATLEPADVAPSHVAFLQYTSGTTGKPKGVMVTHGNLIHNLA
HHHHCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCHHHHHHH
LIGQWMGYHEESTMVSWLPPYHDMGLIGGILTSLFGGFRCVLMAPERFIQHPFLWLRAIS
HHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHHCHHHHHHHHH
DYRADVTGAPDFAYRMCSRRVPDEQLATLDLSCLKTAYSGAESVRYGTLAEFAQRFARTG
HHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCC
FDSERFKPCYGLAECTLLVAGRSAPRPLRTVCVDQAALQQQKVVIRRAFEGLAPQLDERD
CCHHHCCCCCCHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
GERVLVSVGVTIGEQRVVVRDLNTNERCADGEIGEICVAGPSVAPGYWQQYEQTLATFQR
CCEEEEEECCEECCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHH
GIGGETGQAFAGTGDLGFHHRGDLYVTGRLKDMIIIAGRNYYSEDIEYAVIGSRPELVPN
CCCCCCCCCEECCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCEEEECCCCCCCCC
GCAAFTVDAGDEERLVVVAEIERTHRKGDLDALLKGIREAIWLRHDLSPGAVLLVSPGSV
CCEEEEECCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCC
PKTSSGKVRRGECRKRLGDGELTVLARWDADDCIAAATRGDTAANAPSNVPSSAPASAAA
CCCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
TAPAAPAEKTPAADAAGAASPNAAKVEQLKDWLRHYARTRIDSRTIDERRTIPPHIVLDF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHCCHHCCCCCCEEEEEC
GNEGLLGMQIDRAYGGLGLTNREMLQVVSQLATIDSTLAFFVGLNNTLGIRPIMLHAQPA
CCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHH
LRDELLPLLATGRTLAAFALTEPDAGSNARAIASVAQRADGGHWVVSGRKSWSGSSAWAG
HHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHH
VINVFAKQADGAGMVGLALRQGTPGLRIGAEDLTMGVRGMIQNTLHLERARVSDACRLGA
HHHHHHHCCCCCCEEEEEEECCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGQGMAVAQQTMNFARLGIGAVCVGAMKRCAQLMHRYAARRRIGTGLLLDHPLSRQRLGD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHH
LRHRIDALSALIEQLAADFDAGRDAPEDGLLIAKILGSECLSQTSDELMQMLGGRGYIET
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
NVAPQLFRDARLPRIFEGPTETLLAHLGSRLLNGGDDLLGYLGERSGALALAAELRGLGE
CCCHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHH
QLLEDGLANADALGGAAHAANWVNYWLGSVAQWALLLAVVEQAAKRRGVDGATLEWAQSQ
HHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
YELALEAAQRQVGRRRVLASAAQLGEWAQRVEREIGPIEQTVPGATQRVDPLLRAECDVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHHCHHHHCCCCCC
SQPSDIGALDDDEPPAAGVPPAPVPSPASASAEQADPELKREVERWLLTWLGARLRNRRI
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHCCCEE
ALTAETTFADIGLDSILAVELTMAFGDAFRTTVDASAVWDHASIDALATHLAARMDRHAP
EEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCC
AQADAASSAPSASSSL
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Salts [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.0408 {octanoate}} 0.0125 {octanoate}} 0.0059 {octanoate}} 0.00072 {octanoate}} 0.0013 {undecanoate}} 0.0022 {pentadecanoate}} 0.053 {CoA}} 0.035 {CoA}} 0.034 {CoA}} 0.0034 {tridecanoate}} 0.002 {laurate}} 0.0019 {laurate}} 0.0

Substrates: ATP; a long-chain carboxylic acid; CoA [C]

Specific reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate +an acyl-CoA [C]

General reaction: Acid-thiol ligation; Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]