| Definition | Burkholderia pseudomallei 1710b chromosome chromosome II, complete sequence. |
|---|---|
| Accession | NC_007435 |
| Length | 3,181,762 |
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The map label for this gene is fadH [H]
Identifier: 76818202
GI number: 76818202
Start: 1431989
End: 1432960
Strand: Direct
Name: fadH [H]
Synonym: BURPS1710b_A1148
Alternate gene names: 76818202
Gene position: 1431989-1432960 (Clockwise)
Preceding gene: 76817732
Following gene: 76818723
Centisome position: 45.01
GC content: 69.44
Gene sequence:
>972_bases GTGCGCGGCGCGCTTGCGCACGGCCATGCCGGTTGTCGACAGCCGGTTGCGGACGGCCGCTCGCGGACGATCTGTTTGCC GGCTGACTCTCGACTGACGGAAGACTTTCCCATGGGATATCGCTCACAACTTCGCGCAGGCAGCTTCGAAGGCAAGGTCG CGCTCGTCACGGGCGGCGGCAGCGGCATCGGCCGCTGCTGCGCGCACGAACTCGCGTCGCTCGGCGCGCACGTCGCGCTG CTCGGCCGCAACGCGGACAAGCTCGCGAACGTAGCGGCCGAGATTCACGCGGACGGCGGGCGCGCGGACGCGCTCGCCTG CGACATTCGCGACGAAGACGGCGTGCGGCACGCAATCGCGCAAATCGTCGAGCGGCACGGGCGCGTCGATCTGCTCGTGA ACAACGCGGGCGGCCAGTTTCCCGCGCCGCTCGAGCAGATCAGCGCGAAGGGCTGGCAGGCGGTGCTCAACACGAACCTG CTCGGCGGCTTTCTGGTCGCGCGCGAGTGCTACGTGCAATCGATGAAGCCGCGCAAGTCGGGCGCGATCGTCAACATCAT CGCCGACATGTGGCACGGCATGACGGGCATGGGCCACAGCGGCGCGGCGCGCGCCGGCATGCTGAACTTCACCGAGACGG CCGCCGCCGAATGGGCGCCCGTGCGCGTGAATGCGGTCGCGCCCGGCTGGATCGCGTCGAGCGGCATGGACACGTATCCC GATGCGATCAAGCCGATGCTGCGCGGTCTGCCGAAGATGGTGCCGCTCGGGCGCATCGGCAACGAAGCCGAAGTGTCGGC GGCGATCGCGTTCCTGCTGTCGGACGCCGCATCGTTCATCAGCGGCGCGTGCCTGCGCGTCGACGGCGGCGCGCCGAACG CGCGCCGCCACTTCGCGATGCAGCCCACCGACACGAACCCACCGTTCGACGGCTTTCACCGCGCAACCGTGCCCGAACTC TTCAAGCGCTGA
Upstream 100 bases:
>100_bases TAGATTCACGGCGCTACGATGCGCACATCGCACGGCGACCTCCGGGCCGCCCGACGCACGCGCCGTACCCCGCCAGCGCG CCGCCGTCAGCGCCGCATTC
Downstream 100 bases:
>100_bases CATGCCGACCTTCGACTCCCGCCTCGACACCGCGAGCGCCGCGTTCCGCGACAACGCCGAGCACATGCGCGCGCTGATCG CGCAATGGCACGCGCTGAAC
Product: short chain dehydrogenase/reductase family oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 323; Mature: 323
Protein sequence:
>323_residues MRGALAHGHAGCRQPVADGRSRTICLPADSRLTEDFPMGYRSQLRAGSFEGKVALVTGGGSGIGRCCAHELASLGAHVAL LGRNADKLANVAAEIHADGGRADALACDIRDEDGVRHAIAQIVERHGRVDLLVNNAGGQFPAPLEQISAKGWQAVLNTNL LGGFLVARECYVQSMKPRKSGAIVNIIADMWHGMTGMGHSGAARAGMLNFTETAAAEWAPVRVNAVAPGWIASSGMDTYP DAIKPMLRGLPKMVPLGRIGNEAEVSAAIAFLLSDAASFISGACLRVDGGAPNARRHFAMQPTDTNPPFDGFHRATVPEL FKR
Sequences:
>Translated_323_residues MRGALAHGHAGCRQPVADGRSRTICLPADSRLTEDFPMGYRSQLRAGSFEGKVALVTGGGSGIGRCCAHELASLGAHVAL LGRNADKLANVAAEIHADGGRADALACDIRDEDGVRHAIAQIVERHGRVDLLVNNAGGQFPAPLEQISAKGWQAVLNTNL LGGFLVARECYVQSMKPRKSGAIVNIIADMWHGMTGMGHSGAARAGMLNFTETAAAEWAPVRVNAVAPGWIASSGMDTYP DAIKPMLRGLPKMVPLGRIGNEAEVSAAIAFLLSDAASFISGACLRVDGGAPNARRHFAMQPTDTNPPFDGFHRATVPEL FKR >Mature_323_residues MRGALAHGHAGCRQPVADGRSRTICLPADSRLTEDFPMGYRSQLRAGSFEGKVALVTGGGSGIGRCCAHELASLGAHVAL LGRNADKLANVAAEIHADGGRADALACDIRDEDGVRHAIAQIVERHGRVDLLVNNAGGQFPAPLEQISAKGWQAVLNTNL LGGFLVARECYVQSMKPRKSGAIVNIIADMWHGMTGMGHSGAARAGMLNFTETAAAEWAPVRVNAVAPGWIASSGMDTYP DAIKPMLRGLPKMVPLGRIGNEAEVSAAIAFLLSDAASFISGACLRVDGGAPNARRHFAMQPTDTNPPFDGFHRATVPEL FKR
Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=275, Percent_Identity=40.3636363636364, Blast_Score=192, Evalue=3e-49, Organism=Homo sapiens, GI4503301, Length=256, Percent_Identity=33.59375, Blast_Score=131, Evalue=1e-30, Organism=Homo sapiens, GI10190704, Length=271, Percent_Identity=32.4723247232472, Blast_Score=122, Evalue=5e-28, Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=33.4710743801653, Blast_Score=111, Evalue=1e-24, Organism=Homo sapiens, GI32483357, Length=267, Percent_Identity=28.4644194756554, Blast_Score=96, Evalue=3e-20, Organism=Homo sapiens, GI15277342, Length=260, Percent_Identity=30.3846153846154, Blast_Score=89, Evalue=7e-18, Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=27.3809523809524, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI4503817, Length=171, Percent_Identity=31.5789473684211, Blast_Score=83, Evalue=4e-16, Organism=Homo sapiens, GI59889578, Length=200, Percent_Identity=33, Blast_Score=82, Evalue=7e-16, Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=27.3764258555133, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=28.6885245901639, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI31542939, Length=288, Percent_Identity=26.3888888888889, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=29.0816326530612, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI4758504, Length=259, Percent_Identity=27.7992277992278, Blast_Score=75, Evalue=8e-14, Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=29.5336787564767, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=9e-13, Organism=Homo sapiens, GI210032110, Length=142, Percent_Identity=30.2816901408451, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI40254986, Length=148, Percent_Identity=28.3783783783784, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI209862901, Length=152, Percent_Identity=34.8684210526316, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI19923983, Length=152, Percent_Identity=34.8684210526316, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI83715985, Length=257, Percent_Identity=26.8482490272374, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.0645161290323, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=30.8, Blast_Score=104, Evalue=8e-24, Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=30.859375, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=30.7086614173228, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=6e-21, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=30.4, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1790717, Length=246, Percent_Identity=28.4552845528455, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=34.5238095238095, Blast_Score=90, Evalue=2e-19, Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=6e-17, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=31.3725490196078, Blast_Score=79, Evalue=5e-16, Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=26.8199233716475, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787526, Length=196, Percent_Identity=27.0408163265306, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=28.4552845528455, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17536651, Length=270, Percent_Identity=32.962962962963, Blast_Score=128, Evalue=4e-30, Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=32.962962962963, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=31.1787072243346, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=32.520325203252, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17555706, Length=278, Percent_Identity=31.6546762589928, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17561272, Length=262, Percent_Identity=32.824427480916, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=30.0380228136882, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=30.1526717557252, Blast_Score=98, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=29.1187739463602, Blast_Score=98, Evalue=7e-21, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=31.3492063492063, Blast_Score=97, Evalue=9e-21, Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=28.5185185185185, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=32.0158102766798, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=27.6923076923077, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=29.8850574712644, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=30.3846153846154, Blast_Score=91, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17565030, Length=275, Percent_Identity=29.8181818181818, Blast_Score=89, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=29.5719844357977, Blast_Score=88, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=27.0676691729323, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17538486, Length=262, Percent_Identity=28.6259541984733, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=27.3076923076923, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=29.5880149812734, Blast_Score=85, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.811320754717, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17561402, Length=250, Percent_Identity=27.6, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=26.1363636363636, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17551412, Length=262, Percent_Identity=28.2442748091603, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI115534694, Length=251, Percent_Identity=29.4820717131474, Blast_Score=78, Evalue=8e-15, Organism=Caenorhabditis elegans, GI71982365, Length=150, Percent_Identity=29.3333333333333, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI193203115, Length=220, Percent_Identity=28.6363636363636, Blast_Score=75, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17560676, Length=243, Percent_Identity=24.6913580246914, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI72000259, Length=263, Percent_Identity=26.9961977186312, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17567345, Length=169, Percent_Identity=30.1775147928994, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17564282, Length=216, Percent_Identity=30.0925925925926, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17558006, Length=159, Percent_Identity=32.7044025157233, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=31.1284046692607, Blast_Score=124, Evalue=2e-29, Organism=Saccharomyces cerevisiae, GI6322861, Length=223, Percent_Identity=31.8385650224215, Blast_Score=78, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=38.0952380952381, Blast_Score=128, Evalue=6e-30, Organism=Drosophila melanogaster, GI24639444, Length=255, Percent_Identity=33.7254901960784, Blast_Score=127, Evalue=7e-30, Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=35.5731225296443, Blast_Score=127, Evalue=1e-29, Organism=Drosophila melanogaster, GI28571526, Length=264, Percent_Identity=37.5, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI24644339, Length=264, Percent_Identity=36.7424242424242, Blast_Score=119, Evalue=2e-27, Organism=Drosophila melanogaster, GI21355319, Length=250, Percent_Identity=26.8, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=31.4516129032258, Blast_Score=94, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=33.4661354581673, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24641232, Length=214, Percent_Identity=28.9719626168224, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=26.5625, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI116007234, Length=143, Percent_Identity=35.6643356643357, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI116007232, Length=143, Percent_Identity=35.6643356643357, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007236, Length=237, Percent_Identity=27.0042194092827, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21357673, Length=150, Percent_Identity=28.6666666666667, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI24641388, Length=240, Percent_Identity=30, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007238, Length=136, Percent_Identity=33.0882352941176, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI28571387, Length=215, Percent_Identity=27.4418604651163, Blast_Score=66, Evalue=4e-11, Organism=Drosophila melanogaster, GI18859837, Length=218, Percent_Identity=30.7339449541284, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.34 [H]
Molecular weight: Translated: 34005; Mature: 34005
Theoretical pI: Translated: 8.31; Mature: 8.31
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 3.4 %Met (Translated Protein) 5.6 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 3.4 %Met (Mature Protein) 5.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRGALAHGHAGCRQPVADGRSRTICLPADSRLTEDFPMGYRSQLRAGSFEGKVALVTGGG CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCC SGIGRCCAHELASLGAHVALLGRNADKLANVAAEIHADGGRADALACDIRDEDGVRHAIA CCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH QIVERHGRVDLLVNNAGGQFPAPLEQISAKGWQAVLNTNLLGGFLVARECYVQSMKPRKS HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GAIVNIIADMWHGMTGMGHSGAARAGMLNFTETAAAEWAPVRVNAVAPGWIASSGMDTYP CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCH DAIKPMLRGLPKMVPLGRIGNEAEVSAAIAFLLSDAASFISGACLRVDGGAPNARRHFAM HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHEEEE QPTDTNPPFDGFHRATVPELFKR CCCCCCCCCCCCCCCCHHHHHCC >Mature Secondary Structure MRGALAHGHAGCRQPVADGRSRTICLPADSRLTEDFPMGYRSQLRAGSFEGKVALVTGGG CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCCCCCCEEEEEECCC SGIGRCCAHELASLGAHVALLGRNADKLANVAAEIHADGGRADALACDIRDEDGVRHAIA CCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH QIVERHGRVDLLVNNAGGQFPAPLEQISAKGWQAVLNTNLLGGFLVARECYVQSMKPRKS HHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC GAIVNIIADMWHGMTGMGHSGAARAGMLNFTETAAAEWAPVRVNAVAPGWIASSGMDTYP CCHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCH DAIKPMLRGLPKMVPLGRIGNEAEVSAAIAFLLSDAASFISGACLRVDGGAPNARRHFAM HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHEEEE QPTDTNPPFDGFHRATVPELFKR CCCCCCCCCCCCCCCCHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]