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The map label for this gene is kshA [H]

Identifier: 76817889

GI number: 76817889

Start: 1399516

End: 1400556

Strand: Direct

Name: kshA [H]

Synonym: BURPS1710b_A1118

Alternate gene names: 76817889

Gene position: 1399516-1400556 (Clockwise)

Preceding gene: 76819111

Following gene: 76818612

Centisome position: 43.99

GC content: 68.2

Gene sequence:

>1041_bases
GTGGCCGCGAGCTGGTACGTCGCGATGCGCTCGGACGACCTCAAGGACAAGCCGACGGAGCTGACGCTCTTCGGCCGTCC
GTGCGTGGCGTGGCGCGGCGCGACGGGGCGGGCCGTGGTGATGGACCGCCACTGCGCGCACCTCGGCGCGAACCTGGCCG
ACGGGCGGCTCAAGGACGGGTGCATCCAGTGCCCGTTTCACCACTGGCGGTACGACGAGCAGGGCCAGTGCGTTGACATC
CCCGGCCACAGCCTCGCGGTGCGCCGGCTGGAGCCCGTTCCGCGCGGGGCGCGCCAGCCGACGTGGGTCACCGCCGAGCG
ATACGGCTACGTGTGGGTCTGGTACGGTTCCCCGCAGCCGCTGCACCCGCTGCCCGAAATCGCGGCGGCCGACGTCGACA
ACGGCGATTTTATGCACCTGCACTTCGCGTTCGAGACGACGACGGCGGTCTTGCGGATCGTCGAGAACTTCTATGACGCG
CAGCACGCGAACCCCGTGCACGCGCTCCCGATCTCGGCTTTCGAGCTCAAGCTCTTCGACGATTGGCGCGAGTGGCCGGA
GGTCGAATCGCTGGCCCGGGCGGGCGCGTGGTTCGGTGCCGGGATCGACTTCACCGTGGACCGGTACTTCGGGCCCCTCG
GCATGCTGTCGCGCGCGCTCGGCCTGAGCATGTCGCAGATGAACCTGCACTTCGACGGCTACCCCGGCGGGTGCGTCATG
ACCGTCGCCCTGGACGGAAACGTCAAGTACAAGCTGCTCCAGTGCGTGACGCCGGTGAGCGACGGCAAAAACGTCATGCA
CATGCTCATCTCGATCAAGAAGGTGGGCGGCGTCTTGCGCCGCGCGACCGACTTCGTGCTGTTCGGGCTGCAGACCAGAC
AGGCCGCGGGGTACGACGTCAAAATCTGGAACGGGATGAAACCGGACGGCGGCGGCGCGTACAGCAAGTACGACAAGCTC
GTGCTCAAGTACCGCGCGTTCTACCGGGGCTGGGTTGACCGCGTCGCCGAGTCGACCGCTCGACCGCGCCGCCGCGAGTG
A

Upstream 100 bases:

>100_bases
ATAGTCGGCCGACACCGACACGAAAACGATGAACGACGTTCAATTGGATCAAGCGGACATCAAGGAGCATCCCTCGGGGA
CGTACGATGCGACCACGCGC

Downstream 100 bases:

>100_bases
ACGGCGACACGTGAGTCACCACGCGCTTCGTGATGCTAATCGGCAAGCTGTTCGCAGCCGAGGTTCGCCGTGCGAAGGGG
AAGCCCGAACGCCGGCAGCA

Product: PrnD

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MAASWYVAMRSDDLKDKPTELTLFGRPCVAWRGATGRAVVMDRHCAHLGANLADGRLKDGCIQCPFHHWRYDEQGQCVDI
PGHSLAVRRLEPVPRGARQPTWVTAERYGYVWVWYGSPQPLHPLPEIAAADVDNGDFMHLHFAFETTTAVLRIVENFYDA
QHANPVHALPISAFELKLFDDWREWPEVESLARAGAWFGAGIDFTVDRYFGPLGMLSRALGLSMSQMNLHFDGYPGGCVM
TVALDGNVKYKLLQCVTPVSDGKNVMHMLISIKKVGGVLRRATDFVLFGLQTRQAAGYDVKIWNGMKPDGGGAYSKYDKL
VLKYRAFYRGWVDRVAESTARPRRRE

Sequences:

>Translated_346_residues
MAASWYVAMRSDDLKDKPTELTLFGRPCVAWRGATGRAVVMDRHCAHLGANLADGRLKDGCIQCPFHHWRYDEQGQCVDI
PGHSLAVRRLEPVPRGARQPTWVTAERYGYVWVWYGSPQPLHPLPEIAAADVDNGDFMHLHFAFETTTAVLRIVENFYDA
QHANPVHALPISAFELKLFDDWREWPEVESLARAGAWFGAGIDFTVDRYFGPLGMLSRALGLSMSQMNLHFDGYPGGCVM
TVALDGNVKYKLLQCVTPVSDGKNVMHMLISIKKVGGVLRRATDFVLFGLQTRQAAGYDVKIWNGMKPDGGGAYSKYDKL
VLKYRAFYRGWVDRVAESTARPRRRE
>Mature_345_residues
AASWYVAMRSDDLKDKPTELTLFGRPCVAWRGATGRAVVMDRHCAHLGANLADGRLKDGCIQCPFHHWRYDEQGQCVDIP
GHSLAVRRLEPVPRGARQPTWVTAERYGYVWVWYGSPQPLHPLPEIAAADVDNGDFMHLHFAFETTTAVLRIVENFYDAQ
HANPVHALPISAFELKLFDDWREWPEVESLARAGAWFGAGIDFTVDRYFGPLGMLSRALGLSMSQMNLHFDGYPGGCVMT
VALDGNVKYKLLQCVTPVSDGKNVMHMLISIKKVGGVLRRATDFVLFGLQTRQAAGYDVKIWNGMKPDGGGAYSKYDKLV
LKYRAFYRGWVDRVAESTARPRRRE

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=171, Percent_Identity=31.5789473684211, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI161085896, Length=339, Percent_Identity=24.4837758112094, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: NA

Molecular weight: Translated: 38939; Mature: 38808

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASWYVAMRSDDLKDKPTELTLFGRPCVAWRGATGRAVVMDRHCAHLGANLADGRLKDG
CCCEEEEEEECCCCCCCCCEEEEECCCEEEEECCCCCEEEEECHHHHHCCCCCCCCCCCC
CIQCPFHHWRYDEQGQCVDIPGHSLAVRRLEPVPRGARQPTWVTAERYGYVWVWYGSPQP
EEECCHHHCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCEEEEECCEEEEEEECCCCC
LHPLPEIAAADVDNGDFMHLHFAFETTTAVLRIVENFYDAQHANPVHALPISAFELKLFD
CCCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEH
DWREWPEVESLARAGAWFGAGIDFTVDRYFGPLGMLSRALGLSMSQMNLHFDGYPGGCVM
HHHCCHHHHHHHHCCCCCCCCCCEEHHHHCCCHHHHHHHHCCCEEHEEEEECCCCCCEEE
TVALDGNVKYKLLQCVTPVSDGKNVMHMLISIKKVGGVLRRATDFVLFGLQTRQAAGYDV
EEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEE
KIWNGMKPDGGGAYSKYDKLVLKYRAFYRGWVDRVAESTARPRRRE
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AASWYVAMRSDDLKDKPTELTLFGRPCVAWRGATGRAVVMDRHCAHLGANLADGRLKDG
CCEEEEEEECCCCCCCCCEEEEECCCEEEEECCCCCEEEEECHHHHHCCCCCCCCCCCC
CIQCPFHHWRYDEQGQCVDIPGHSLAVRRLEPVPRGARQPTWVTAERYGYVWVWYGSPQP
EEECCHHHCCCCCCCCEEECCCCCEEEEECCCCCCCCCCCCEEEEECCEEEEEEECCCCC
LHPLPEIAAADVDNGDFMHLHFAFETTTAVLRIVENFYDAQHANPVHALPISAFELKLFD
CCCCCHHHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEH
DWREWPEVESLARAGAWFGAGIDFTVDRYFGPLGMLSRALGLSMSQMNLHFDGYPGGCVM
HHHCCHHHHHHHHCCCCCCCCCCEEHHHHCCCHHHHHHHHCCCEEHEEEEECCCCCCEEE
TVALDGNVKYKLLQCVTPVSDGKNVMHMLISIKKVGGVLRRATDFVLFGLQTRQAAGYDV
EEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEE
KIWNGMKPDGGGAYSKYDKLVLKYRAFYRGWVDRVAESTARPRRRE
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]