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The map label for this gene is cynR [H]

Identifier: 76817866

GI number: 76817866

Start: 1609467

End: 1610423

Strand: Direct

Name: cynR [H]

Synonym: BURPS1710b_A1297

Alternate gene names: 76817866

Gene position: 1609467-1610423 (Clockwise)

Preceding gene: 76819838

Following gene: 76819019

Centisome position: 50.58

GC content: 68.13

Gene sequence:

>957_bases
ATGCGAGAGATCAACCATCAACGCCTGCGGTATTTCCACGAAGTCCTGACCCACGGCACCATCCGCGGCGCGGCGGACCA
CATCAACACGTCGCCGTCCGTCATCACGCGGCAGATCCGGCTGCTCGAGGAAGAGCTCGGCGCCGCGCTATTCGAGCGGC
AGGCGCGCGGCGTGCGGCCGACGGAGGCCGCCGCGCACCTGCTCGAGTTCTGGCGGGGCTACCGGTCGCAGCAGGAAAAG
CTCGAAGATCAGCTTCACGCGCTCAAGGGCCTTCAGCAGGGGCACATCCGGATAGTCGTCAGCGAGGGGTTCGTCGACAC
GCTCGTCGACGACGTGCTCGCGCCGTTCTGCGCGAAGTATCCGAAGCTGAATGTCGACGTCGACATGCTCGCGGTCGACA
CGATACTGGACGAAGTGGCGCTCAGCCGCGCGCACATCGGGCTCGCGTACAATCCGCCGCCGCATCCGCTGATCGCGCAT
CGCGCGAGCTCGCGGCAGCCGGTCGTGCTGCTGTTGCGGCGCGATCATCCGCTCGCGCGACGCAGGCGGCCGGCGACCGT
CGACGATCTGCACGCGTACCCGCTCGCGCTGATGCCGCCGACGTTCGGCATCGGCCACGTGGTGAAGATGCTGGAGCTGG
CCGAGAACATCGAGATCCGGCCGACGTTGACGACGAATTCGCTGACGGCGCTCAAGCGCATCGTCACGGCGGAGAACTTC
ATCACGCTGATCGGAGCATTCGCCGCGTACCGCGAAATCGCGGCCGGCGAGCTGACGACGGTGCCGATCGCGCACCCGAT
ATTCGAGGGCACGCATGCGCGGCTGATCGTGAAATCGGGGCGGCCGCTGGCGCCGGCGCCGGTGGAATTGATCCGGTGGA
TCGAGACGCGGTTGGCGGTGTTCGCGGCCGCGACGGGCGGCGGCGGGAAAACGCGCGGGCGGCGCGGCACGCGGTGA

Upstream 100 bases:

>100_bases
GTGCAGGCATGTTGGCAGCGCGCTGCCCTACTAGCAAGAGCAACCAAGTTCACATATCGTTGCCCTGTGAACAACGGTGA
ATCGAGCCGGGAGCGAATCG

Downstream 100 bases:

>100_bases
CGCCTTTCGTTCGGCGCCGCACGCTCGAGCCGGTGAAGATCGCCGCTTGCGGCCCGGTTGCGGCCCGTTTACTGCGCGCG
GAAAACAAAGGCTCGGCTTC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Cyn operon transcriptional activator [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MREINHQRLRYFHEVLTHGTIRGAADHINTSPSVITRQIRLLEEELGAALFERQARGVRPTEAAAHLLEFWRGYRSQQEK
LEDQLHALKGLQQGHIRIVVSEGFVDTLVDDVLAPFCAKYPKLNVDVDMLAVDTILDEVALSRAHIGLAYNPPPHPLIAH
RASSRQPVVLLLRRDHPLARRRRPATVDDLHAYPLALMPPTFGIGHVVKMLELAENIEIRPTLTTNSLTALKRIVTAENF
ITLIGAFAAYREIAAGELTTVPIAHPIFEGTHARLIVKSGRPLAPAPVELIRWIETRLAVFAAATGGGGKTRGRRGTR

Sequences:

>Translated_318_residues
MREINHQRLRYFHEVLTHGTIRGAADHINTSPSVITRQIRLLEEELGAALFERQARGVRPTEAAAHLLEFWRGYRSQQEK
LEDQLHALKGLQQGHIRIVVSEGFVDTLVDDVLAPFCAKYPKLNVDVDMLAVDTILDEVALSRAHIGLAYNPPPHPLIAH
RASSRQPVVLLLRRDHPLARRRRPATVDDLHAYPLALMPPTFGIGHVVKMLELAENIEIRPTLTTNSLTALKRIVTAENF
ITLIGAFAAYREIAAGELTTVPIAHPIFEGTHARLIVKSGRPLAPAPVELIRWIETRLAVFAAATGGGGKTRGRRGTR
>Mature_318_residues
MREINHQRLRYFHEVLTHGTIRGAADHINTSPSVITRQIRLLEEELGAALFERQARGVRPTEAAAHLLEFWRGYRSQQEK
LEDQLHALKGLQQGHIRIVVSEGFVDTLVDDVLAPFCAKYPKLNVDVDMLAVDTILDEVALSRAHIGLAYNPPPHPLIAH
RASSRQPVVLLLRRDHPLARRRRPATVDDLHAYPLALMPPTFGIGHVVKMLELAENIEIRPTLTTNSLTALKRIVTAENF
ITLIGAFAAYREIAAGELTTVPIAHPIFEGTHARLIVKSGRPLAPAPVELIRWIETRLAVFAAATGGGGKTRGRRGTR

Specific function: Positively regulates the cynTSX operon, and negatively regulates its own transcription. Binds specifically to the cynR- cynTSX intergenic region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=308, Percent_Identity=26.2987012987013, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35343; Mature: 35343

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50931 HTH_LYSR ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREINHQRLRYFHEVLTHGTIRGAADHINTSPSVITRQIRLLEEELGAALFERQARGVRP
CCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TEAAAHLLEFWRGYRSQQEKLEDQLHALKGLQQGHIRIVVSEGFVDTLVDDVLAPFCAKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHC
PKLNVDVDMLAVDTILDEVALSRAHIGLAYNPPPHPLIAHRASSRQPVVLLLRRDHPLAR
CCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCCCCCEEEEEECCCCHHH
RRRPATVDDLHAYPLALMPPTFGIGHVVKMLELAENIEIRPTLTTNSLTALKRIVTAENF
CCCCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
ITLIGAFAAYREIAAGELTTVPIAHPIFEGTHARLIVKSGRPLAPAPVELIRWIETRLAV
HHHHHHHHHHHHHHCCCCEECCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
FAAATGGGGKTRGRRGTR
HHEECCCCCCCCCCCCCC
>Mature Secondary Structure
MREINHQRLRYFHEVLTHGTIRGAADHINTSPSVITRQIRLLEEELGAALFERQARGVRP
CCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TEAAAHLLEFWRGYRSQQEKLEDQLHALKGLQQGHIRIVVSEGFVDTLVDDVLAPFCAKY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHC
PKLNVDVDMLAVDTILDEVALSRAHIGLAYNPPPHPLIAHRASSRQPVVLLLRRDHPLAR
CCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCCCCCEEEEEECCCCHHH
RRRPATVDDLHAYPLALMPPTFGIGHVVKMLELAENIEIRPTLTTNSLTALKRIVTAENF
CCCCCCHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHH
ITLIGAFAAYREIAAGELTTVPIAHPIFEGTHARLIVKSGRPLAPAPVELIRWIETRLAV
HHHHHHHHHHHHHHCCCCEECCCHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
FAAATGGGGKTRGRRGTR
HHEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]