Click here to switch to the map view.

The map label for this gene is cckA [C]

Identifier: 76817790

GI number: 76817790

Start: 1308294

End: 1310129

Strand: Direct

Name: cckA [C]

Synonym: BURPS1710b_A1041

Alternate gene names: 76817790

Gene position: 1308294-1310129 (Clockwise)

Preceding gene: 76819634

Following gene: 76819560

Centisome position: 41.12

GC content: 69.93

Gene sequence:

>1836_bases
ATGCACGTCGAGGTATTCGCACAACACCCAAGTTGTCCCGGCTGGCACGGCGAAATGGCCCGGCGCATCCGTGCGTTCGA
CTGGTCCGCCACCGAGCTCGGGCCGCTCGAGCGCTGGCCGGCCAGCCTCGTCGCCGCCGTGCGCACGGTGCTCGCGTCGC
CGGTCCCGCTCGTGATGCTGTGGGGCGCGTCCGGCTACATGCTCTACAACGACGCCTATGCGGCGTTCGCGGGCGGCCGT
CATCCGTATTTGCTCGGCCAGCCGGTCGAGCTCGGCTGGCCCGAAGTGGCCGATTTCAATCGCAACGTGATGCGCACGTG
CCTCGCGGGCGGCGCGCTGTCGTATCGCGACAAGGCGCTCGTGCTGCTGCGCAACGGCCGCCCGGAAGAAGTCTGGATGG
ATTTGTACTACAGCCCCCTCGCGGGCGACGACGGCGCGCCCGCCGGCGTGCTCGCGGTCGTCGTGGAGACCACCGAGCGG
GTGCTCGCCGCGCGGCATCGCGATCGTGCGAAGGCGGCGCTGCACGAAACCAACGCCGAGCTGCGCCGGCTCACCGAGAC
GCTCGAACAGCGGGTAGCGGACGCGATCACCGAACGCGCGTCGATCGAGGAGCAATTGCGTCAGGCGCAAAAGATGGAAG
CGATCGGCAGCCTGACGGGCGGCATCGCGCACGATTTCAACAACGTGCTGCAAGTGGTCAGCAGCAATCTGCAAATGCTC
TCGGCCGAACTCGGCGAAGACGCCCGCGCGCAGCGCCGCATCGCGAGCGCCGCCAACGCGGTGGCGCGCGGCGCGCAGCT
CGCGTCGCATCTGCTCGCGTTCGCGAGGCGCCAGCCGTTGGCGCCGGCGGTGCTCGAACCGCGCGGGCTCATCGACGGCA
TGAGGGAAATGCTGCATCGGGCGCTCGGCGAATCGGTCCATGTCGATGCCGATCTGCGCGACGACGTCTGGAACGTGCTC
GCGGATCGCCATCAGTTCGAGAACGCGCTGCTCAATCTCGCGATCAACGCGCGCGATGCGATGCGCGGCGAAGGCACGCT
GAAGATCACCGCGTGCAACATCGTGCTCGAAGCGGGCCGTCACGCGCGGCGCAACGGGTTGCCGCCCGGCGAGTACGTCG
CGTTCGACATCGCCGACAACGGCGTCGGCATGACGCCCGACATACTGGAGCGGGTGTTCGAGCCGTTTTTCACGACGAAG
CCGGACGGCCAGGGCACGGGCCTCGGGCTCAGCATGGTGTTCGGCTTCGTCAAGCAGAGCGGCGGCCACACGTCGATCGA
AAGCGCGCCGGGCCGCGGCACCACGGTGCGGCTGCTGCTTCCGCGCTGTCGCGAAGCGCCGGCCGGCGAGCCGGCCGCGC
AGCGGCGGCTTCCGGCCGAGGGCGGCCGCGAGACGATCCTCGTCGTCGAGGACGATGCGGACGTGCGGCTCGCCGTCGTC
GACATGCTCGCGCAGCTCGGCTACAAGGTGATCACCGCATCGGACGGCGAAGCGGGCCTTCTCGCGCTCGAAAGCGGAGC
GCCGATCGATTTGCTGTTCACCGACGTGATCATGCCCGGCCGCATCAAGGGCGGCGAACTGGCGCGGCGAGCGGCGCAGC
GCGTGCCGCCCGTGCCCGTGCTGTTCACGTCCGGCTACACGCGCGACGAGATCTTCCACGCGGGACGGCTCGATCCTGGC
GTGATGCTGCTCGGCAAGCCGTACCGGCGCGACGAGCTCGCACACAAGGTGCGCAGCGTGCTCGACGCACATGCGTCGGC
GCGGCGCGCTCACGGCGCGCGGCACGCGCAGGCGGACCCTCGCGCGAAAACGGCCGCCGCGCGTGTGCAGCGGTAG

Upstream 100 bases:

>100_bases
CGCCTCGTCGCATCGCGCGCCGATCCTGTTCTAGAATGAGCGGGCGATCGCGCTGCGCAGCACGTGGAGCGCGCCGCCAC
GTTCGTCACGGAGCGCACGC

Downstream 100 bases:

>100_bases
CGCGAAGCACGACGCTGGCACTGGCACTGGCGCTGGCGATGCTACCGGCGGCGAAACGCTCGTCCGGGCGCTTCGCTTGC
CGTGCGTGCGCGGCGTTCAC

Product: sensory box histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 611; Mature: 611

Protein sequence:

>611_residues
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGR
HPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTER
VLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLRDDVWNVL
ADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTK
PDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
DMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPG
VMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR

Sequences:

>Translated_611_residues
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGR
HPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTER
VLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLRDDVWNVL
ADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTK
PDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
DMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPG
VMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>Mature_611_residues
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGR
HPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTER
VLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLRDDVWNVL
ADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTK
PDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
DMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPG
VMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=28.2945736434109, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=26.2096774193548, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=396, Percent_Identity=23.7373737373737, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=31.1688311688312, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI48994928, Length=284, Percent_Identity=26.056338028169, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66333; Mature: 66333

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00584 PFKB_KINASES_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVML
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
WGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKAL
ECCCCEEEECCCHHHHCCCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCEE
VLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAE
EEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGR
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCCEEEEEEEHHHHHCCC
HARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQS
HHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
GGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
CCCCCCCCCCCCCCEEEEECHHHCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCHHHHH
DMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPV
HHHHHCCCEEEEECCCCCCEEEECCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHCCCCCE
LFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADP
EECCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RAKTAAARVQR
HHHHHHHHCCC
>Mature Secondary Structure
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVML
CCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
WGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKAL
ECCCCEEEECCCHHHHCCCCCCEEECCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCCCEE
VLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAE
EEEECCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHR
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
ALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGR
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHEEECCHHHHCCCCEEEEEEEHHHHHCCC
HARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQS
HHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCC
GGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVV
CCCCCCCCCCCCCCEEEEECHHHCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCHHHHH
DMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPV
HHHHHCCCEEEEECCCCCCEEEECCCCCEEEHHHHHCCCCCCCCHHHHHHHHHHCCCCCE
LFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADP
EECCCCCHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RAKTAAARVQR
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA