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The map label for this gene is tcp [H]

Identifier: 76817773

GI number: 76817773

Start: 319948

End: 321342

Strand: Direct

Name: tcp [H]

Synonym: BURPS1710b_A0212

Alternate gene names: 76817773

Gene position: 319948-321342 (Clockwise)

Preceding gene: 76818508

Following gene: 76817761

Centisome position: 10.06

GC content: 68.6

Gene sequence:

>1395_bases
GTGAGCGAGCATTTCTACAAACTGTCGCAGCAGAACGCGATGCCCGAGGCCGACGCGAAGCGCGCCGCGCTCGAAGCGAT
CGCCGCGATGCGCTACGGCAAGGACGGCTATCTGTCGGTCAACGATTCGAAGCCCGTCGTCGTCATGCATCCGATCAAGC
CGGAGCTGAACGGCAAGGACGTGTCGGGCTTCACCGATCCGGGCGGCAAGCATCTGTTCGTCGAGATCGTCAAGGCGGGC
AACGCGGAAGGCGGCCTCGGCTTCGTCGACTACATGTGGCCGAAGCCGGGCGCCGACAAGCCGATCGACAAGACGAGCGC
CGTTCGCCATTTCGCGCCGTGGGACTGGTACCTCGTGACCGGCATGTACATGGACGACCTGCAGGCCGCCGTGCTCGCGA
GCACGGGCCGCTGGCTCGCGATGACGGCCGTGCTCGGCGCCGCCGCGACGATCCTGATGGTGCTCGTGCTGCGCAGCGTG
CGCAGCAGCCTCGGCGGCGATCTCGAAGCGGCCGTCGCGACCGCGCAGCGCATCGCGCAGGGCGACCTGACCGCGCACGT
CGACATTCGCGGCGGCGATCGCAAGAGCCTCCTGCACGCGCTGCACACGATGCAGACGGCGCTCATCGACATGGTCTCGC
GCGTGCGGCTCGGCACCGAGAACATCAACGTCGGCGCATCGGAGATCGCGGCCGGCAACACGGATCTGTCGCAGCGCACC
GAGCAGCAGGCGGCCGCGCTCGTCGAGACCGCGTCGAGCATGGACGAGATGACGACGAACGTGAAGCAGAACGCGGACAG
CGCGTCGCAGGCGGCCGAGCTCGCCGACCAGGCGGCGCAGGTCGCCACGCGCGGCAGCTCGGTCGTCGACGACGTCGTGC
GCACGATGGACGAGATCACCGACGCGTCGCGCAAGATCGGCGACATCATCGGCGTGATCGACGGCATCGCGTTCCAGACC
AACATCCTTGCGCTCAACGCGGCCGTCGAGGCGGCGCGCGCGGGCGAGCAGGGCCGCGGCTTCGCGGTCGTCGCGGGCGA
GGTGCGCACGCTCGCGCAGCGCTCGGCCACGGCCGCGAAGGAAATCAAGTCGCTGATCGAGACATCGAACACGACGGTCG
AGCACGGCGCGACGCTCGTCACGCGCGCGGGCACGACGATGACGGAAATCGTGCAATCGGTGAGGCGCGTGAACGAGATC
CTCGAGGAAATCAGCCATGCGTCGCGCGAACAGAGCGCGGGCATCGACCAGGTGAATCGCGCGGTCGGCGAGATGGACCA
GGTCACGCAGCAGAACGCCGCGCTCGTCGAACAGGCGGCCGCCGCCGCGCATTCGCTGAAGGATCAGGCGGATGCGCTGC
GCTCGGCGGTCGCGCAATTCGCGCTGCCGGGTTGA

Upstream 100 bases:

>100_bases
CCTGCTGCTGATCGGCGCGACCGGCGCATGGCAGAACCGCTCGTCGATGATCGCGGACCGGCGCGAGCAGCTCGCCTATC
TGACCGCGCAGGCGTACAAC

Downstream 100 bases:

>100_bases
GCGTTTGATCGCCTGACCACCTGACCACCTGACCACCTGATCGCCTGACCGCCGATCGGTGGATTCGCCGGCGGCGGCGA
GACGAGGCGGCTCGGCCGGC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSEHFYKLSQQNAMPEADAKRAALEAIAAMRYGKDGYLSVNDSKPVVVMHPIKPELNGKDVSGFTDPGGKHLFVEIVKAG
NAEGGLGFVDYMWPKPGADKPIDKTSAVRHFAPWDWYLVTGMYMDDLQAAVLASTGRWLAMTAVLGAAATILMVLVLRSV
RSSLGGDLEAAVATAQRIAQGDLTAHVDIRGGDRKSLLHALHTMQTALIDMVSRVRLGTENINVGASEIAAGNTDLSQRT
EQQAAALVETASSMDEMTTNVKQNADSASQAAELADQAAQVATRGSSVVDDVVRTMDEITDASRKIGDIIGVIDGIAFQT
NILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIKSLIETSNTTVEHGATLVTRAGTTMTEIVQSVRRVNEI
LEEISHASREQSAGIDQVNRAVGEMDQVTQQNAALVEQAAAAAHSLKDQADALRSAVAQFALPG

Sequences:

>Translated_464_residues
MSEHFYKLSQQNAMPEADAKRAALEAIAAMRYGKDGYLSVNDSKPVVVMHPIKPELNGKDVSGFTDPGGKHLFVEIVKAG
NAEGGLGFVDYMWPKPGADKPIDKTSAVRHFAPWDWYLVTGMYMDDLQAAVLASTGRWLAMTAVLGAAATILMVLVLRSV
RSSLGGDLEAAVATAQRIAQGDLTAHVDIRGGDRKSLLHALHTMQTALIDMVSRVRLGTENINVGASEIAAGNTDLSQRT
EQQAAALVETASSMDEMTTNVKQNADSASQAAELADQAAQVATRGSSVVDDVVRTMDEITDASRKIGDIIGVIDGIAFQT
NILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIKSLIETSNTTVEHGATLVTRAGTTMTEIVQSVRRVNEI
LEEISHASREQSAGIDQVNRAVGEMDQVTQQNAALVEQAAAAAHSLKDQADALRSAVAQFALPG
>Mature_463_residues
SEHFYKLSQQNAMPEADAKRAALEAIAAMRYGKDGYLSVNDSKPVVVMHPIKPELNGKDVSGFTDPGGKHLFVEIVKAGN
AEGGLGFVDYMWPKPGADKPIDKTSAVRHFAPWDWYLVTGMYMDDLQAAVLASTGRWLAMTAVLGAAATILMVLVLRSVR
SSLGGDLEAAVATAQRIAQGDLTAHVDIRGGDRKSLLHALHTMQTALIDMVSRVRLGTENINVGASEIAAGNTDLSQRTE
QQAAALVETASSMDEMTTNVKQNADSASQAAELADQAAQVATRGSSVVDDVVRTMDEITDASRKIGDIIGVIDGIAFQTN
ILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAKEIKSLIETSNTTVEHGATLVTRAGTTMTEIVQSVRRVNEIL
EEISHASREQSAGIDQVNRAVGEMDQVTQQNAALVEQAAAAAHSLKDQADALRSAVAQFALPG

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=286, Percent_Identity=59.4405594405594, Blast_Score=298, Evalue=6e-82,
Organism=Escherichia coli, GI1788195, Length=304, Percent_Identity=58.8815789473684, Blast_Score=291, Evalue=5e-80,
Organism=Escherichia coli, GI2367378, Length=296, Percent_Identity=57.0945945945946, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI1787690, Length=328, Percent_Identity=51.5243902439024, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1789453, Length=246, Percent_Identity=45.9349593495935, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 49100; Mature: 48969

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHFYKLSQQNAMPEADAKRAALEAIAAMRYGKDGYLSVNDSKPVVVMHPIKPELNGKD
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCC
VSGFTDPGGKHLFVEIVKAGNAEGGLGFVDYMWPKPGADKPIDKTSAVRHFAPWDWYLVT
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEH
GMYMDDLQAAVLASTGRWLAMTAVLGAAATILMVLVLRSVRSSLGGDLEAAVATAQRIAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GDLTAHVDIRGGDRKSLLHALHTMQTALIDMVSRVRLGTENINVGASEIAAGNTDLSQRT
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHH
EQQAAALVETASSMDEMTTNVKQNADSASQAAELADQAAQVATRGSSVVDDVVRTMDEIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DASRKIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIKSLIETSNTTVEHGATLVTRAGTTMTEIVQSVRRVNEILEEISHASREQSAGIDQVNR
HHHHHHHCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AVGEMDQVTQQNAALVEQAAAAAHSLKDQADALRSAVAQFALPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEHFYKLSQQNAMPEADAKRAALEAIAAMRYGKDGYLSVNDSKPVVVMHPIKPELNGKD
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCCCCC
VSGFTDPGGKHLFVEIVKAGNAEGGLGFVDYMWPKPGADKPIDKTSAVRHFAPWDWYLVT
CCCCCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHCCCCCEEEEH
GMYMDDLQAAVLASTGRWLAMTAVLGAAATILMVLVLRSVRSSLGGDLEAAVATAQRIAQ
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GDLTAHVDIRGGDRKSLLHALHTMQTALIDMVSRVRLGTENINVGASEIAAGNTDLSQRT
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCHHHHH
EQQAAALVETASSMDEMTTNVKQNADSASQAAELADQAAQVATRGSSVVDDVVRTMDEIT
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DASRKIGDIIGVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLAQRSATAAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHH
EIKSLIETSNTTVEHGATLVTRAGTTMTEIVQSVRRVNEILEEISHASREQSAGIDQVNR
HHHHHHHCCCCCHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
AVGEMDQVTQQNAALVEQAAAAAHSLKDQADALRSAVAQFALPG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]