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The map label for this gene is fnrL [H]

Identifier: 76817622

GI number: 76817622

Start: 157358

End: 158137

Strand: Direct

Name: fnrL [H]

Synonym: BURPS1710b_A0129

Alternate gene names: 76817622

Gene position: 157358-158137 (Clockwise)

Preceding gene: 76818833

Following gene: 76818747

Centisome position: 4.95

GC content: 65.77

Gene sequence:

>780_bases
ATGTTGCAAGCGCAAACGCAGAACGCCTACACGCCCGCGCAGCAGCGCGTAACGGTGCCGTTGCGCGCGGCGAAGTGCGA
TGACGCGGCCAAGCGTACGGCGGCGCGCTGCTCGAGCTGCGCGATGCGCAGCGTCTGCATGCCCGTCGACCTGAACACCC
ACGAATTCGCGAAGCTCGACGCGCTGATCTGCTCGACGCGCCAGGTCAAGCGCGGCGACACGCTGTTCCGCACGAATGAC
GGCTTCCAGAGCATCTATGCGGTGCGCACCGGCTCGTTCAAGACGGTCGTCATGCATCGCGACGGCCAGGAGCACGTGAC
GGGTTTCCAGATCGTCGGTGAAACGCTCGGCCTCGACGGCGTGTGCGCCGGGCACCACAACAGCGATGCGGTCGCGCTCG
AGGACAGCACCGTGTGCATCATCCCGTTCGCGCAGCTCGAGGCGGTGTGCCGCGAGGTGAAGCCGATGCAGCACCACGTG
CACCGGCTGATGAGCGGCGAGATCGTCCGCGAGTCGAGCCAGATGATGCTGCTCGGCACGATGACGGCCGAGCAGCGCGT
CGCCGCGTTCCTGCTCAACATTTCGGAGCGCTTCCAGAAGCGCGGCTACTCGGCGGCGGAATTCAACCTGCGGATGACCC
GCGAGGAAATCGGCTGCTACCTCGGGATGAAGCTCGAGACGGTCAGCCGGATGCTGTCGAAGTTCCAGCGCGACAAGCTG
ATCGCGCCGCGCGGCAAGCAGATTCGCATCATCGATCCGGTGGGTCTCGCGCGCGTGTAA

Upstream 100 bases:

>100_bases
CTTCTTCGACAAGACCGCCGACGTGGACGCCGCCTGTCGCACCGTGAGAACCCTGGCCGGCGCGCACCGCCCGCGCGCGG
CCGAATGACAGGAGCAGATC

Downstream 100 bases:

>100_bases
TGGCGGCCGCGCGGATCGCGGACAGAACAATCGCTACGGGGAAGCAGGCAGCTACGGGGAAAAAGAAGAAAGACAGGCAG
GCCGAACGCGGCGAGGACAG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MLQAQTQNAYTPAQQRVTVPLRAAKCDDAAKRTAARCSSCAMRSVCMPVDLNTHEFAKLDALICSTRQVKRGDTLFRTND
GFQSIYAVRTGSFKTVVMHRDGQEHVTGFQIVGETLGLDGVCAGHHNSDAVALEDSTVCIIPFAQLEAVCREVKPMQHHV
HRLMSGEIVRESSQMMLLGTMTAEQRVAAFLLNISERFQKRGYSAAEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDKL
IAPRGKQIRIIDPVGLARV

Sequences:

>Translated_259_residues
MLQAQTQNAYTPAQQRVTVPLRAAKCDDAAKRTAARCSSCAMRSVCMPVDLNTHEFAKLDALICSTRQVKRGDTLFRTND
GFQSIYAVRTGSFKTVVMHRDGQEHVTGFQIVGETLGLDGVCAGHHNSDAVALEDSTVCIIPFAQLEAVCREVKPMQHHV
HRLMSGEIVRESSQMMLLGTMTAEQRVAAFLLNISERFQKRGYSAAEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDKL
IAPRGKQIRIIDPVGLARV
>Mature_259_residues
MLQAQTQNAYTPAQQRVTVPLRAAKCDDAAKRTAARCSSCAMRSVCMPVDLNTHEFAKLDALICSTRQVKRGDTLFRTND
GFQSIYAVRTGSFKTVVMHRDGQEHVTGFQIVGETLGLDGVCAGHHNSDAVALEDSTVCIIPFAQLEAVCREVKPMQHHV
HRLMSGEIVRESSQMMLLGTMTAEQRVAAFLLNISERFQKRGYSAAEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDKL
IAPRGKQIRIIDPVGLARV

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=41.1504424778761, Blast_Score=202, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28879; Mature: 28879

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAQTQNAYTPAQQRVTVPLRAAKCDDAAKRTAARCSSCAMRSVCMPVDLNTHEFAKLD
CCCCCCCCCCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEECCCCCHHHHHHH
ALICSTRQVKRGDTLFRTNDGFQSIYAVRTGSFKTVVMHRDGQEHVTGFQIVGETLGLDG
HHHHCCHHHCCCCCEEEECCCHHEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
VCAGHHNSDAVALEDSTVCIIPFAQLEAVCREVKPMQHHVHRLMSGEIVRESSQMMLLGT
EEECCCCCCEEEEECCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHCHHHHCCCCEEEEEE
MTAEQRVAAFLLNISERFQKRGYSAAEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDKL
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHCCC
IAPRGKQIRIIDPVGLARV
CCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MLQAQTQNAYTPAQQRVTVPLRAAKCDDAAKRTAARCSSCAMRSVCMPVDLNTHEFAKLD
CCCCCCCCCCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEECCCCCHHHHHHH
ALICSTRQVKRGDTLFRTNDGFQSIYAVRTGSFKTVVMHRDGQEHVTGFQIVGETLGLDG
HHHHCCHHHCCCCCEEEECCCHHEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCC
VCAGHHNSDAVALEDSTVCIIPFAQLEAVCREVKPMQHHVHRLMSGEIVRESSQMMLLGT
EEECCCCCCEEEEECCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHCHHHHCCCCEEEEEE
MTAEQRVAAFLLNISERFQKRGYSAAEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDKL
CCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHCCCCCCCHHHHHHHHHHHHHCCC
IAPRGKQIRIIDPVGLARV
CCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]