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The map label for this gene is fnrL [H]

Identifier: 76817368

GI number: 76817368

Start: 1281123

End: 1281905

Strand: Direct

Name: fnrL [H]

Synonym: BURPS1710b_A1016

Alternate gene names: 76817368

Gene position: 1281123-1281905 (Clockwise)

Preceding gene: 76817925

Following gene: 76817319

Centisome position: 40.26

GC content: 66.28

Gene sequence:

>783_bases
ATGCTGACCGCCTCTGTCAATGAAGCAGAGCCCTGCGCCGAGCCGCAGCGGCCGGTGATCAGGCTGCATCCCGTGACGGC
CGACGACGCGCCGAAGCTGCCGGCGACCCGCTGCTCGACCTGCGCGATACGCAACGTGTGCATGCCGGCCGGCCTCACGC
CGATCGAATTCGCGCGGCTCGACGCGATGGTCTGCACGACGCGCCACGTCAAGCGCGGCGACGCGCTGTTCCGCACGCAC
GACACGTTCCAGAGCATCTATGCGGTGCGCACCGGCTCGTTCAAGACGGTCGTCATGCACCGCGACGGCCGCGAGCAGGT
AACGGGCTTCCAGATCGTCGGCGAGACGCTCGGGCTGGACGGCGTGTGCGGCGGCCGCCACAACAGCGATGCGATCGCGC
TCGAGGACAGCACCGTGTGCATCATCCCGTTCGCGCAGCTCGAGGCGGTGTGCCGCGAGGTGAAGCCGATGCAGCACCAC
GTGCATCAGTTGATGAGCGGCGAGATCGTTCGCGAATCGAGCCTGATGATGCTGCTCGGCACGATGACGGCCGAGCAGCG
CGTTGCCGCATTCCTGCTCAATATTTCCGAGCGTTTCCAGAAGCGCGGCTATTCGGCATCGGAATTCAACCTGCGGATGA
CGCGCGAGGAAATCGGCTGCTACCTCGGGATGAAGCTCGAGACGGTCAGCCGGATGCTGTCGAAGTTCCAGCGCGACCGG
TTGATCGCGCCGCGCGGCAAGCAGATCCGCATCACCGATCCGCAGGGGCTCGCGCGCGTGTGA

Upstream 100 bases:

>100_bases
GCTTCGTCGACGCCGTCGCGCAAAGCGGCACCGCGTGCCGCGCCACGTGTACGCCACGTCCGCCGTGCCAGTCGGGCGTC
GCGCATGAAAGGAGCCGATT

Downstream 100 bases:

>100_bases
CGCGCCGCTGCGGCGGCGCGTTGCGAAGCGGCCGCGCCGGCGTGTTGAAGTGTGGATGTATCGGTATTTCGATGCGTCGA
CGTTTCAATGCGCGGCCGCG

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLTASVNEAEPCAEPQRPVIRLHPVTADDAPKLPATRCSTCAIRNVCMPAGLTPIEFARLDAMVCTTRHVKRGDALFRTH
DTFQSIYAVRTGSFKTVVMHRDGREQVTGFQIVGETLGLDGVCGGRHNSDAIALEDSTVCIIPFAQLEAVCREVKPMQHH
VHQLMSGEIVRESSLMMLLGTMTAEQRVAAFLLNISERFQKRGYSASEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDR
LIAPRGKQIRITDPQGLARV

Sequences:

>Translated_260_residues
MLTASVNEAEPCAEPQRPVIRLHPVTADDAPKLPATRCSTCAIRNVCMPAGLTPIEFARLDAMVCTTRHVKRGDALFRTH
DTFQSIYAVRTGSFKTVVMHRDGREQVTGFQIVGETLGLDGVCGGRHNSDAIALEDSTVCIIPFAQLEAVCREVKPMQHH
VHQLMSGEIVRESSLMMLLGTMTAEQRVAAFLLNISERFQKRGYSASEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDR
LIAPRGKQIRITDPQGLARV
>Mature_260_residues
MLTASVNEAEPCAEPQRPVIRLHPVTADDAPKLPATRCSTCAIRNVCMPAGLTPIEFARLDAMVCTTRHVKRGDALFRTH
DTFQSIYAVRTGSFKTVVMHRDGREQVTGFQIVGETLGLDGVCGGRHNSDAIALEDSTVCIIPFAQLEAVCREVKPMQHH
VHQLMSGEIVRESSLMMLLGTMTAEQRVAAFLLNISERFQKRGYSASEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDR
LIAPRGKQIRITDPQGLARV

Specific function: May regulate gene expression in response to changes in oxygen levels or to changes in the redox potential of the bacterial environment [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=226, Percent_Identity=39.3805309734513, Blast_Score=190, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 28974; Mature: 28974

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTASVNEAEPCAEPQRPVIRLHPVTADDAPKLPATRCSTCAIRNVCMPAGLTPIEFARL
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
DAMVCTTRHVKRGDALFRTHDTFQSIYAVRTGSFKTVVMHRDGREQVTGFQIVGETLGLD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHEEEHHHCCCC
GVCGGRHNSDAIALEDSTVCIIPFAQLEAVCREVKPMQHHVHQLMSGEIVRESSLMMLLG
CCCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCHHHHHHH
TMTAEQRVAAFLLNISERFQKRGYSASEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCHHCCHHHHHHHHHHHHHHCC
LIAPRGKQIRITDPQGLARV
CCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MLTASVNEAEPCAEPQRPVIRLHPVTADDAPKLPATRCSTCAIRNVCMPAGLTPIEFARL
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHH
DAMVCTTRHVKRGDALFRTHDTFQSIYAVRTGSFKTVVMHRDGREQVTGFQIVGETLGLD
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHEEEHHHCCCC
GVCGGRHNSDAIALEDSTVCIIPFAQLEAVCREVKPMQHHVHQLMSGEIVRESSLMMLLG
CCCCCCCCCCEEEEECCCEEEEEHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCHHHHHHH
TMTAEQRVAAFLLNISERFQKRGYSASEFNLRMTREEIGCYLGMKLETVSRMLSKFQRDR
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCHHCCHHHHHHHHHHHHHHCC
LIAPRGKQIRITDPQGLARV
CCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7693656; 12910271 [H]