BacMap

Definition	Burkholderia pseudomallei 1710b chromosome chromosome II, complete sequence.
Accession	NC_007435
Length	3,181,762

Click here to switch to the map view.

The map label for this gene is benD [H]

Identifier: 76817354

GI number: 76817354

Start: 1267321

End: 1268115

Strand: Direct

Name: benD [H]

Synonym: BURPS1710b_A1002

Alternate gene names: 76817354

Gene position: 1267321-1268115 (Clockwise)

Preceding gene: 76818275

Following gene: 76819332

Centisome position: 39.83

GC content: 72.08

Gene sequence:

>795_bases
ATGAATACTCATCACGCACCCGGCCGCTTCAGCGGCAAGGTGACGATCGTCACGGGCGCCGCGCAGGGCATCGGCCGCGG
CGTCGCGCGGCGCGCGGCGCGCGAAGGCGCGACGGCCGTGCTCGTCGATCGCGCGGACCTCGTGCACGAGGCGGCGGCCG
ATATCGTCACGGCGGGCGGCCGCGCACTCGCCGTCGTCGCCGATCTCGAAACGTATGCGGGCGCCGAAGCGATGGCGCGC
GCGGCCGTCGACGCGTTCGGCTCGATCGACGTGCTCGTCAACAACGTCGGCGGTACGATCTGGACGAGGCCGTTCGACCG
CTACGAAGCCGCGCAGATCGAAGCGGAGATCCGCCGTTCGCTGTTCCCGACGCTGTGGTGCTGCCGCGCGGTGCTGCCCG
GCATGATCGCGCGCGGCGGCGGCGCGATCGTCAACGTATCGTCGATCGCGACGCGCAGCGTTCATCGCGTGCCGTACGCG
GCCGCCAAAGGCGGCGTCAACGCCCTGACCGCCAGCCTCGCGTTCGAGCACGCCGCGCACGGCGTGCGCGTGAACGCGGT
CGCCGCGGGCGGCACCGACGCGCCGCCGCGCAAGGTGCCGCGCAACACGGAGCCGCAGGGCGACGACGATGCGCGCTGGT
ATCGCGCCATCGTCGACCAGACGCTGTCGTCGAGCCTGATGCACCGCTACGGCACGATCGACGAGCAGGTCGCCGCGATC
CTGTTTCTCGCGTCCGACGAGGCGTCGTACATCACCGGCTCGGTGCTGCCCGTCGGCGGCGGCGATCAGGGCTGA

Upstream 100 bases:

>100_bases
GCCCGGCGCCGATGGTCGACGCGGTGCAGGCCTGGCTGCGCGAGCGCGGCGTCACGCCGGCCAATCTGTACTTCGAAAAA
TTCTCGTCGAGCAACGCACC

Downstream 100 bases:

>100_bases
GCGGCCGCACGGCCGCCCATTGCGCGGCGCCCGTCGCCCGCGCTCAGGCAGGCGCGCGCGGCGCGGCGCGCACGAATGCG
GCGACGTCGTCGAGCACCGG

Product: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase

Products: NA

Alternate protein names: 2-hydro-1,2-dihydroxybenzoate dehydrogenase; DHB dehydrogenase; Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase; Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MNTHHAPGRFSGKVTIVTGAAQGIGRGVARRAAREGATAVLVDRADLVHEAAADIVTAGGRALAVVADLETYAGAEAMAR
AAVDAFGSIDVLVNNVGGTIWTRPFDRYEAAQIEAEIRRSLFPTLWCCRAVLPGMIARGGGAIVNVSSIATRSVHRVPYA
AAKGGVNALTASLAFEHAAHGVRVNAVAAGGTDAPPRKVPRNTEPQGDDDARWYRAIVDQTLSSSLMHRYGTIDEQVAAI
LFLASDEASYITGSVLPVGGGDQG

Sequences:

>Translated_264_residues
MNTHHAPGRFSGKVTIVTGAAQGIGRGVARRAAREGATAVLVDRADLVHEAAADIVTAGGRALAVVADLETYAGAEAMAR
AAVDAFGSIDVLVNNVGGTIWTRPFDRYEAAQIEAEIRRSLFPTLWCCRAVLPGMIARGGGAIVNVSSIATRSVHRVPYA
AAKGGVNALTASLAFEHAAHGVRVNAVAAGGTDAPPRKVPRNTEPQGDDDARWYRAIVDQTLSSSLMHRYGTIDEQVAAI
LFLASDEASYITGSVLPVGGGDQG
>Mature_264_residues
MNTHHAPGRFSGKVTIVTGAAQGIGRGVARRAAREGATAVLVDRADLVHEAAADIVTAGGRALAVVADLETYAGAEAMAR
AAVDAFGSIDVLVNNVGGTIWTRPFDRYEAAQIEAEIRRSLFPTLWCCRAVLPGMIARGGGAIVNVSSIATRSVHRVPYA
AAKGGVNALTASLAFEHAAHGVRVNAVAAGGTDAPPRKVPRNTEPQGDDDARWYRAIVDQTLSSSLMHRYGTIDEQVAAI
LFLASDEASYITGSVLPVGGGDQG

Specific function: Degradation of 2-hydro-1,2-dihydroxy benzoate (DHB) to catechol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=28.8888888888889, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI32483357, Length=268, Percent_Identity=30.2238805970149, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=32.8185328185328, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI66933014, Length=267, Percent_Identity=29.2134831460674, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI40254992, Length=255, Percent_Identity=30.1960784313725, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=261, Percent_Identity=27.2030651340996, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI10190704, Length=265, Percent_Identity=29.811320754717, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=28.7313432835821, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI59889578, Length=219, Percent_Identity=28.310502283105, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=260, Percent_Identity=28.8461538461538, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4504505, Length=198, Percent_Identity=32.8282828282828, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI40254986, Length=192, Percent_Identity=26.0416666666667, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI209862901, Length=199, Percent_Identity=28.1407035175879, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI19923983, Length=199, Percent_Identity=28.1407035175879, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=34.6007604562738, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=33.59375, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=30.6201550387597, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.8897637795276, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=31.5175097276265, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1789378, Length=267, Percent_Identity=28.0898876404494, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788459, Length=265, Percent_Identity=27.5471698113208, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=26.6409266409266, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=259, Percent_Identity=32.4324324324324, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=258, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=31.4814814814815, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17531453, Length=201, Percent_Identity=35.3233830845771, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=31.1594202898551, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=189, Percent_Identity=34.3915343915344, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=198, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=197, Percent_Identity=34.010152284264, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI72000259, Length=189, Percent_Identity=31.7460317460317, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=189, Percent_Identity=33.8624338624339, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=30.2583025830258, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=29.3040293040293, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=271, Percent_Identity=29.520295202952, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=32, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=194, Percent_Identity=31.9587628865979, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=27.2373540856031, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=29.811320754717, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17563726, Length=189, Percent_Identity=31.7460317460317, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=273, Percent_Identity=30.03663003663, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=28.7822878228782, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=252, Percent_Identity=29.7619047619048, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=262, Percent_Identity=31.2977099236641, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=28.8659793814433, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=28.6245353159851, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=254, Percent_Identity=27.5590551181102, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17568967, Length=209, Percent_Identity=29.1866028708134, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=264, Percent_Identity=28.030303030303, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=29.5918367346939, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=36.5384615384615, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=35.2490421455939, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=34.375, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=35.361216730038, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=33.4600760456274, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=30.6818181818182, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355319, Length=268, Percent_Identity=26.865671641791, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640492, Length=203, Percent_Identity=27.0935960591133, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=28.7937743190661, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21357673, Length=227, Percent_Identity=27.3127753303965, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI18859837, Length=199, Percent_Identity=31.1557788944724, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076933, Length=181, Percent_Identity=31.4917127071823, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24584748, Length=181, Percent_Identity=31.4917127071823, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.25 [H]

Molecular weight: Translated: 27410; Mature: 27410

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTHHAPGRFSGKVTIVTGAAQGIGRGVARRAAREGATAVLVDRADLVHEAAADIVTAGG
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCC
RALAVVADLETYAGAEAMARAAVDAFGSIDVLVNNVGGTIWTRPFDRYEAAQIEAEIRRS
CEEEEEECHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHH
LFPTLWCCRAVLPGMIARGGGAIVNVSSIATRSVHRVPYAAAKGGVNALTASLAFEHAAH
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHC
GVRVNAVAAGGTDAPPRKVPRNTEPQGDDDARWYRAIVDQTLSSSLMHRYGTIDEQVAAI
CEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEE
LFLASDEASYITGSVLPVGGGDQG
EEEECCCCCEEECCEEECCCCCCC
>Mature Secondary Structure
MNTHHAPGRFSGKVTIVTGAAQGIGRGVARRAAREGATAVLVDRADLVHEAAADIVTAGG
CCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCC
RALAVVADLETYAGAEAMARAAVDAFGSIDVLVNNVGGTIWTRPFDRYEAAQIEAEIRRS
CEEEEEECHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCEECCCCHHHHHHHHHHHHHHH
LFPTLWCCRAVLPGMIARGGGAIVNVSSIATRSVHRVPYAAAKGGVNALTASLAFEHAAH
HHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHC
GVRVNAVAAGGTDAPPRKVPRNTEPQGDDDARWYRAIVDQTLSSSLMHRYGTIDEQVAAI
CEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEE
LFLASDEASYITGSVLPVGGGDQG
EEEECCCCCEEECCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1740120 [H]