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The map label for this gene is mocR [H]

Identifier: 76817266

GI number: 76817266

Start: 1070011

End: 1071531

Strand: Direct

Name: mocR [H]

Synonym: BURPS1710b_A0817

Alternate gene names: 76817266

Gene position: 1070011-1071531 (Clockwise)

Preceding gene: 76817576

Following gene: 76818348

Centisome position: 33.63

GC content: 69.36

Gene sequence:

>1521_bases
GTGATCCTCTCCGACTGGCTTGCCGCGCGACTCGAGCGGCACTCGGCCGAGCCGATGTACCGGCAACTGCTGCGGCTGAT
GCAGCAGGCGATCCTCTCGGGGGAGCTCACGCCCGGCACGAAGCTGCCGAGCTCGCGCACGCTCGCCACCGATCTCGCGA
TCGCGCGCAACACCGTGCTGCACGTGTACGACCAACTGACGACGGAAGGCTACGTGCTGACGACGACGGGCAGCGGCACC
TACGTCGCCGACACGCGCCCCGATGCCGCGGCGATGCGCGCGCAAGCCGGCGCGCCCGCGCATCCGTCAGACGAAACGCG
CGACGCGCAGCAGCGCGCGCACGGCGCGCTGTCGGCGCGCGGCGCGCAACTGATCCGGCATGCGGGCGTGTCGCGCCGCC
AGTGGGGCGCGTTCATGCCGGGCGTGCCCGACGTGTCCGAGTTTCCGACGCGTACATGGAGCCGCCTGCAGGCGCGGCTG
TGGAAGGAAGCGAATCCGGAGCTGCTGACCTATGCGCCGGGCGGCGGCTACCGGCCGTTGCGGCGCGCGCTGTCCGACTA
CCTGCGCGTCGCGCGCTCGGTCAAATGCTCGCCCGATCAGATCATCATCACGACGGGCATTCATCAGTCGATCGACCTGT
CGGTGCGCCTGCTCGCCGACGTCGGCGATCGCGCGTGGGTCGAGGAGCCGTGCTACTGGGGCGTGCGCAGCGTGCTGCAG
GCGGCGGGGCTCGCACTCGCGCCCGTGCCCGTCGATCAGGAAGGGCTCGCGCCGCGCGCGCAGGACCTGAAGCGCCCGCC
GCGGCTCGTGCTCGTCACGCCGTCGCATCAATATCCGCTCGGCATGGTGATGAGCCTCGCGCGGCGCCGGATGCTGCTCG
AATATGCGCGGCAGCATCAATGCTGGATCATCGAAGACGACTACGACAGCGAGTTCCGCTACGGCAGCCGTCCGCTCGCG
TCGCTACAGGGGCTCGACGACGCGGGCCGCGTGATCTACGTCGGCAGTCTCGGCAAGATGCTGTTCCCGAGCCTGCGCCT
CGGCTACATGGTCGTGCCCGAGCACCTCGTCGAGACCTTCCGGACCGGGCTGTCGGAGCTGTATCGCGAAGGGCAACTGA
TGCAGCAGGCGGTGCTCGCCGAATTCATCATGGACGGCTATCTGACGTCGCACGTGCGCCGGATGCGCGCGCTGTACGGC
GAGCGCCGCCAGTTGCTGATCGACGCGATCCACTCGCGCTTCGGCGATGCGCTGCCGGTGATGGGCGACGAGGCGGGCCT
GCACCTCGTGATCGGATTGCCGAACGGCTGCGACGACCGGGCGATCACGCAGACCGCGTTCGACGCGGGGGTGATCGTGC
GCCCGCTCACGACGTACTACAACCATGCGGATACCGCGCGCGAGGGATTGCTGCTCGGCTACGCATGCGTGCCGAACGAG
CGCATCGCGCCCGCGTTCGAGACGCTCGCGCAGATAATCGAAGCGCATCTGAATCGGCGTGCGAAGCAACGGGCCGCGTG
A

Upstream 100 bases:

>100_bases
GTCTTGGCTCGATATTGCGAGATGCGATTCACTATACGGCGCGCACGGTTCTACAATAGGGAACCATTTCAATATTTCCG
GTAGAACCACTTTGGACACC

Downstream 100 bases:

>100_bases
TGCATGCAATTCGCGCGATGCGCGCGGCGTTCGACACGCACCGCCTGCTCGTTACGCCGACGCGCCGCGCGCGCACGCCT
GCCGCGCGCATCGGACATGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVLHVYDQLTTEGYVLTTTGSGT
YVADTRPDAAAMRAQAGAPAHPSDETRDAQQRAHGALSARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARL
WKEANPELLTYAPGGGYRPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRSVLQ
AAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQCWIIEDDYDSEFRYGSRPLA
SLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYG
ERRQLLIDAIHSRFGDALPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACVPNE
RIAPAFETLAQIIEAHLNRRAKQRAA

Sequences:

>Translated_506_residues
MILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVLHVYDQLTTEGYVLTTTGSGT
YVADTRPDAAAMRAQAGAPAHPSDETRDAQQRAHGALSARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARL
WKEANPELLTYAPGGGYRPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRSVLQ
AAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQCWIIEDDYDSEFRYGSRPLA
SLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYG
ERRQLLIDAIHSRFGDALPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACVPNE
RIAPAFETLAQIIEAHLNRRAKQRAA
>Mature_506_residues
MILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVLHVYDQLTTEGYVLTTTGSGT
YVADTRPDAAAMRAQAGAPAHPSDETRDAQQRAHGALSARGAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARL
WKEANPELLTYAPGGGYRPLRRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRSVLQ
AAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQCWIIEDDYDSEFRYGSRPLA
SLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETFRTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYG
ERRQLLIDAIHSRFGDALPVMGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACVPNE
RIAPAFETLAQIIEAHLNRRAKQRAA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=389, Percent_Identity=23.9074550128535, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI33469970, Length=389, Percent_Identity=23.9074550128535, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1787710, Length=485, Percent_Identity=26.3917525773196, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790797, Length=423, Percent_Identity=27.1867612293144, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6321236, Length=318, Percent_Identity=23.2704402515723, Blast_Score=70, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356535, Length=256, Percent_Identity=24.609375, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56251; Mature: 56251

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HVYDQLTTEGYVLTTTGSGTYVADTRPDAAAMRAQAGAPAHPSDETRDAQQRAHGALSAR
HHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARLWKEANPELLTYAPGGGYRPL
HHHHHHHCCCCHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
RRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRSVLQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHEEHHCCCCHHHCCCHHHHHHHHHH
AAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQ
HCCCEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
CWIIEDDYDSEFRYGSRPLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETF
CEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCEECHHHHHHHH
RTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYGERRQLLIDAIHSRFGDALPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACVPNE
CCCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHCCEEEEEEECCCC
RIAPAFETLAQIIEAHLNRRAKQRAA
CCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILSDWLAARLERHSAEPMYRQLLRLMQQAILSGELTPGTKLPSSRTLATDLAIARNTVL
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
HVYDQLTTEGYVLTTTGSGTYVADTRPDAAAMRAQAGAPAHPSDETRDAQQRAHGALSAR
HHHHHHCCCCEEEEECCCCCEEECCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
GAQLIRHAGVSRRQWGAFMPGVPDVSEFPTRTWSRLQARLWKEANPELLTYAPGGGYRPL
HHHHHHHCCCCHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHH
RRALSDYLRVARSVKCSPDQIIITTGIHQSIDLSVRLLADVGDRAWVEEPCYWGVRSVLQ
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHEEHHCCCCHHHCCCHHHHHHHHHH
AAGLALAPVPVDQEGLAPRAQDLKRPPRLVLVTPSHQYPLGMVMSLARRRMLLEYARQHQ
HCCCEECCCCCCCCCCCCCHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCC
CWIIEDDYDSEFRYGSRPLASLQGLDDAGRVIYVGSLGKMLFPSLRLGYMVVPEHLVETF
CEEEECCCCCCCCCCCCCHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCEECHHHHHHHH
RTGLSELYREGQLMQQAVLAEFIMDGYLTSHVRRMRALYGERRQLLIDAIHSRFGDALPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
MGDEAGLHLVIGLPNGCDDRAITQTAFDAGVIVRPLTTYYNHADTAREGLLLGYACVPNE
CCCCCCEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHCCHHHHHCCEEEEEEECCCC
RIAPAFETLAQIIEAHLNRRAKQRAA
CCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]