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The map label for this gene is dspA [H]

Identifier: 75910058

GI number: 75910058

Start: 4797486

End: 4798646

Strand: Direct

Name: dspA [H]

Synonym: Ava_3854

Alternate gene names: 75910058

Gene position: 4797486-4798646 (Clockwise)

Preceding gene: 75910057

Following gene: 75910064

Centisome position: 75.36

GC content: 38.5

Gene sequence:

>1161_bases
ATGGTTGGACACTCAGTCAGGATTTTATTAATTGAGGATAGCCTCGCAGAAGCTAGGTTATTACAGGAATATTTGCATCA
AGCTGAGTCCAAACAATTTGTTCTGGTTCATGTGACGCGATTACAGGAAGCACTCAATGAACTCAAACAGACCAGCTACG
ATGTGATTTTGTTAGACCTCACCCTACCGGATAGCCAAGGATTATCATCTTTACCCAGATTAATAGGACTCGCTCCCAGC
GTACCAATTGTTGTCTTAACAAATACTAACGATGAAGACTTAGCAATTGAAGCAGTCAGACAGGGAGCGCAAGATTATTT
AGTTAAGCGACAGGTAAATGTTCATGTTTTGGTTCGTGCTGTATGTTATGCAATCGAGCGTAAGCAAGCATTAGAAACAT
TACGCACCATGAATACAACCTTAGAAAACCGGGTGGAAGAACGCACGGCTGAATTGGTAAAAGCGCAGGAAATTAACCAG
TTTAAATCTGAGTTTGTTTCTATGCTCTCCCATGACATTCGTAATCCCTTGAATACTATTTTGCTAGCTGCTGGGTTGTT
GCAAAACAATGAAGACAAATTAACCCAAGAGAAAAAACGTTCTCATTTACAAATGATTCGTTCCGCCATTAAAAATATGG
CACAGCTATTAGATGAAGTATCATTAATAGGTAAAGCTGAATCAGGTAAACTCCAGTGTGAACTTATCGCTATAGATTTG
GAAGCATTCTGTCGTCAGTTATTAGCAGAAGCGCAATTAACTATAGGCGAGAAGCAGCTGACTGTAATTTTTACCTGTAA
TAAAAAATTTGATGAAGCCTTATTAGATGAAACCTTGTTGCGTCACATTTTAGGTAATGTATTAGGCAACGCTATTAAAT
ATTCCCTTCCCGGTGGTATGATCCACTTTGAATTGACTGCTAACAATAATGCAGTCATGTTTAAAATTCAAGATTGCGGC
ATTGGTATTTCTCCCCAAGATCAAAAGAATTTATTTCAATCATTCCATCGTGGGGAAAATGTAGGAGGAATAGCAGGTAC
TGGTTTAGGGCTAGCTATTGTTAAAAAATGTGTTGATGCTCACGGTGGTGAAATTATCGTTAATAGTGAGGTTGGGGTTG
GTACAACCTTTACTATCATCTTGCCATTAATCAACTTTTAA

Upstream 100 bases:

>100_bases
AAGAAGACAAAGTAGATGGAAATTCTTCTCTCTCCCCAGTCCCCAATCCCCAATCCCCAATCCCCAATCACTACTTTCAA
GGGGGTAAAACCAGAAAATT

Downstream 100 bases:

>100_bases
ATGTGTGATATGTTCTCTATATTTCTGTGGTAAAAAGTTGTTGTCTAGGGAGACTTTTTATAAAATAAATGTTAAGAAAA
ATTAAACGCAGATGCACGCA

Product: response regulator receiver signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MVGHSVRILLIEDSLAEARLLQEYLHQAESKQFVLVHVTRLQEALNELKQTSYDVILLDLTLPDSQGLSSLPRLIGLAPS
VPIVVLTNTNDEDLAIEAVRQGAQDYLVKRQVNVHVLVRAVCYAIERKQALETLRTMNTTLENRVEERTAELVKAQEINQ
FKSEFVSMLSHDIRNPLNTILLAAGLLQNNEDKLTQEKKRSHLQMIRSAIKNMAQLLDEVSLIGKAESGKLQCELIAIDL
EAFCRQLLAEAQLTIGEKQLTVIFTCNKKFDEALLDETLLRHILGNVLGNAIKYSLPGGMIHFELTANNNAVMFKIQDCG
IGISPQDQKNLFQSFHRGENVGGIAGTGLGLAIVKKCVDAHGGEIIVNSEVGVGTTFTIILPLINF

Sequences:

>Translated_386_residues
MVGHSVRILLIEDSLAEARLLQEYLHQAESKQFVLVHVTRLQEALNELKQTSYDVILLDLTLPDSQGLSSLPRLIGLAPS
VPIVVLTNTNDEDLAIEAVRQGAQDYLVKRQVNVHVLVRAVCYAIERKQALETLRTMNTTLENRVEERTAELVKAQEINQ
FKSEFVSMLSHDIRNPLNTILLAAGLLQNNEDKLTQEKKRSHLQMIRSAIKNMAQLLDEVSLIGKAESGKLQCELIAIDL
EAFCRQLLAEAQLTIGEKQLTVIFTCNKKFDEALLDETLLRHILGNVLGNAIKYSLPGGMIHFELTANNNAVMFKIQDCG
IGISPQDQKNLFQSFHRGENVGGIAGTGLGLAIVKKCVDAHGGEIIVNSEVGVGTTFTIILPLINF
>Mature_386_residues
MVGHSVRILLIEDSLAEARLLQEYLHQAESKQFVLVHVTRLQEALNELKQTSYDVILLDLTLPDSQGLSSLPRLIGLAPS
VPIVVLTNTNDEDLAIEAVRQGAQDYLVKRQVNVHVLVRAVCYAIERKQALETLRTMNTTLENRVEERTAELVKAQEINQ
FKSEFVSMLSHDIRNPLNTILLAAGLLQNNEDKLTQEKKRSHLQMIRSAIKNMAQLLDEVSLIGKAESGKLQCELIAIDL
EAFCRQLLAEAQLTIGEKQLTVIFTCNKKFDEALLDETLLRHILGNVLGNAIKYSLPGGMIHFELTANNNAVMFKIQDCG
IGISPQDQKNLFQSFHRGENVGGIAGTGLGLAIVKKCVDAHGGEIIVNSEVGVGTTFTIILPLINF

Specific function: Member Of The Two-Component Regulatory System Uvry/Bara Involved In The Regulation Of Carbon Metabolism Via The Csra/Csrb Regulatory System. Phosphorylates Uvry, Probably Via A Four-Step Phosphorelay. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=32.618025751073, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=29.3333333333333, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=232, Percent_Identity=27.1551724137931, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=30.5220883534137, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=277, Percent_Identity=28.8808664259928, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=26.0683760683761, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788279, Length=224, Percent_Identity=26.3392857142857, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=26.890756302521, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=29.2792792792793, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1789808, Length=215, Percent_Identity=26.9767441860465, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=24.7787610619469, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=241, Percent_Identity=24.896265560166, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790436, Length=216, Percent_Identity=27.7777777777778, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082128, Length=224, Percent_Identity=23.6607142857143, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=24.6696035242291, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790861, Length=210, Percent_Identity=24.7619047619048, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789403, Length=208, Percent_Identity=26.4423076923077, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42733; Mature: 42733

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGHSVRILLIEDSLAEARLLQEYLHQAESKQFVLVHVTRLQEALNELKQTSYDVILLDL
CCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEE
TLPDSQGLSSLPRLIGLAPSVPIVVLTNTNDEDLAIEAVRQGAQDYLVKRQVNVHVLVRA
ECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHH
VCYAIERKQALETLRTMNTTLENRVEERTAELVKAQEINQFKSEFVSMLSHDIRNPLNTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAAGLLQNNEDKLTQEKKRSHLQMIRSAIKNMAQLLDEVSLIGKAESGKLQCELIAIDL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECH
EAFCRQLLAEAQLTIGEKQLTVIFTCNKKFDEALLDETLLRHILGNVLGNAIKYSLPGGM
HHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCE
IHFELTANNNAVMFKIQDCGIGISPQDQKNLFQSFHRGENVGGIAGTGLGLAIVKKCVDA
EEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
HGGEIIVNSEVGVGTTFTIILPLINF
CCCEEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MVGHSVRILLIEDSLAEARLLQEYLHQAESKQFVLVHVTRLQEALNELKQTSYDVILLDL
CCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCEEEEEE
TLPDSQGLSSLPRLIGLAPSVPIVVLTNTNDEDLAIEAVRQGAQDYLVKRQVNVHVLVRA
ECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHCCHHHHHHHH
VCYAIERKQALETLRTMNTTLENRVEERTAELVKAQEINQFKSEFVSMLSHDIRNPLNTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAAGLLQNNEDKLTQEKKRSHLQMIRSAIKNMAQLLDEVSLIGKAESGKLQCELIAIDL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECH
EAFCRQLLAEAQLTIGEKQLTVIFTCNKKFDEALLDETLLRHILGNVLGNAIKYSLPGGM
HHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCE
IHFELTANNNAVMFKIQDCGIGISPQDQKNLFQSFHRGENVGGIAGTGLGLAIVKKCVDA
EEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
HGGEIIVNSEVGVGTTFTIILPLINF
CCCEEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8535519; 8905231; 3141423 [H]