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The map label for this gene is mnmG

Identifier: 75909745

GI number: 75909745

Start: 4404865

End: 4406787

Strand: Direct

Name: mnmG

Synonym: Ava_3539

Alternate gene names: 75909745

Gene position: 4404865-4406787 (Clockwise)

Preceding gene: 75909743

Following gene: 75909746

Centisome position: 69.2

GC content: 48.1

Gene sequence:

>1923_bases
ATGACCATGCACAATTCAGTGGAATTTCAAGACGCTTTTGATGTCATTGTCGTCGGTGCAGGTCACTCCGGTTGCGAAGC
GGCGCTTGCTACTGCCCGCCTCGGCTGTCGTACCTTGTTACTGACGCTCAATTTGGATAAAATTGCGTGGCAACCCTGTA
ATCCGGCTGTGGGTGGGCCTGCTAAATCCCAGTTGACCCATGAGGTAGATGCTTTGGGCGGGGAAATTGGCAAGATGGCA
GACCGCACATATCTACAAAAGCGCATCCTCAACTCTTCACGAGGGCCTGCGGTGTGGGCATTACGCGCCCAAACTGACAA
GCGGGAATATGCGGCTATCATGAAAAATATTGTGGAGAATCAAGAGAACTTGAGCATCCGCGAGAGTATGGTGACGGACT
TGGTTCTGGGTGCTAATGATGAAGTGATAGGTGTGGAAACCTACTTTGGCGTAGCTTTCCAGTGTAAAGCCGTAATTTTA
ACCACAGGTACATTTCTAGGTGGAAAAATTTGGGTAGGTAACAAATCCATGCCAGCCGGACGTGCTGGGGAGTTTGCGGC
TGAGGGATTAACCGAAACCCTAAATCGTTTGGGATTTGAAACTGGTAGGTTAAAGACTGGTACACCCGCACGGGTAGATA
AGCGGTCAGTAGATTACAGTAAGATGCAGCTCCAGCCAGGGGATGAGGAAGTGCGTTGGTTTAGTTTTGACCCGGATGTG
TGGGTAGAACGGGAACAGCTACCTTGTCACATGACCCGCACCACCCCCGAAACTCATCGCCTGATTCGAGAAAACTTGCA
CCTATCACCTGTGTATGGTGGTTGGGTAGAAGCCAAAGGCCCTCGTTATTGCCCCAGTATTGAAGATAAGATTGTCCGCT
TTGTGGATAAAGAAAGTCATCAAATCTTTATTGAGCCGGAGGGACGGGATATTCCTGAATTATATATCCAAGGGTTTTCT
ACAGGGTTGCCCGAAAATTTGCAACTACAGATGCTACGTAGTCTCCCTGGGTTGGAAAATTGCGTTATGTTACGTCCAGC
TTATGCTGTGGAATATGACTACTTACCTGCAACTCAGTGTTACCCCACACTGATGACGAAGAAGGTTGCTGGCTTGTTTT
GTGCGGGACAGGTGAATGGTACAACCGGTTATGAAGAAGCCGCAGCCCAAGGTATTGTAGCCGGAATTAATGCGGCGCGG
TTTGTCCGGGATCAGGAAATGATAGTTTTTCCCCGTGAGCAAAGCTATTTAGGCACTTTAGTTGATGACCTATGTACAAA
AGACCTCCGGGAACCTTATCGGATGCTTACCAGCCGTTCCGAATATCGCTTGCTGCTACGTTCTGATAACTCTGACCAGC
GCCTAACTCCTCTAGGAAGGGAAATTGGCTTAATTGATGACCGTCGTTGGCAACTGTTTACCCGCAAACAGGAGCAGATT
ACAGGTGAGAAAGAACGGCTGTATGCTACCAGAGTAAAAGAAAATGATGAAGTAGGCAAAGCGATCGCCTCTAATACCCA
ACAAGCCATTAAAGGTTCAATCACCTTGGCTGACTTACTGCGTCGCCCTGGCTTCCATTATGTAGACCTCGATAGATACG
GGTTAGGAAACCCCGAACTTACCCCAGCCGAAAGAGAAGGGGCAGAAATTGACATCAAATACTCTGGCTATCTTGCCAGA
CAACAAAGCCAAATCGAACAGATTGCCCGTCAAGCACAGCGCCAATTACCAAGGGATTTGGATTACACAACTGTGGAAAC
CCTCTCCAAAGAAGCGCGGGAAAAACTGAATAAGGTCAAACCCATGACCATTGGTCAAGCAGCCCGAATCGGTGGAGTCA
ATCCAGCCGACATTAACGCCTTATTAATTTATTTAGAATTGCGTCAAACCAAGCACCAGACAGGATTAGCCGCTTTACCT
TAA

Upstream 100 bases:

>100_bases
CTGGGCAATGCTCACCCTATATATAATTCATAAATCAAATATTAGTCCTATAGATTAGGTTAGAATCAGGAATAAATCTC
AGCTTGTTAATCCTGTACGT

Downstream 100 bases:

>100_bases
CTTCATCTTTATCAAGGGTGAGTATAGTAGAGGGAGGGATGGGTATGATAGATGACAAGAATTCAGAACTGGCATCATCA
ATTGATCCCCGCTTTTGAGT

Product: tRNA uridine 5-carboxymethylaminomethyl modification protein GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 640; Mature: 639

Protein sequence:

>640_residues
MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMA
DRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVIL
TTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDV
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFS
TGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAAR
FVRDQEMIVFPREQSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQI
TGEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEREGAEIDIKYSGYLAR
QQSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVKPMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP

Sequences:

>Translated_640_residues
MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMA
DRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVIL
TTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDV
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFS
TGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAAR
FVRDQEMIVFPREQSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQI
TGEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEREGAEIDIKYSGYLAR
QQSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVKPMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP
>Mature_639_residues
TMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMAD
RTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILT
TGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDVW
VEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFST
GLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAARF
VRDQEMIVFPREQSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQIT
GEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEREGAEIDIKYSGYLARQ
QSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVKPMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=644, Percent_Identity=41.6149068322981, Blast_Score=431, Evalue=1e-120,
Organism=Homo sapiens, GI19882217, Length=669, Percent_Identity=40.0597907324365, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI183227703, Length=684, Percent_Identity=39.1812865497076, Blast_Score=411, Evalue=1e-115,
Organism=Escherichia coli, GI2367273, Length=619, Percent_Identity=49.2730210016155, Blast_Score=588, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI17534255, Length=623, Percent_Identity=39.4863563402889, Blast_Score=437, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6321202, Length=647, Percent_Identity=42.3493044822257, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24658174, Length=636, Percent_Identity=42.1383647798742, Blast_Score=441, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_ANAVT (Q3M790)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_324041.1
- HSSP:   Q5SH33
- ProteinModelPortal:   Q3M790
- SMR:   Q3M790
- STRING:   Q3M790
- GeneID:   3679563
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_3539
- NMPDR:   fig|240292.3.peg.4379
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q3M790
- ProtClustDB:   PRK05192
- BioCyc:   AVAR240292:AVA_3539-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 71591; Mature: 71459

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGP
CCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEEHHHHCCCCCCCCCCCC
AKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVEN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
QENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILTTGTFLGGKIWVGNKSMPAG
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHCEEEEEEEEEEEECCEECCEEEECCCCCCCC
RAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCCC
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESH
EEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCC
QIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQC
EEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEECCCCCHHH
YPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAARFVRDQEMIVFPREQSYLGTL
HHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEEECCCHHHHHHH
VDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQI
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TGEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPEL
CCCHHHHHHHHCCCCHHHHHHHHHCHHHHHHCCCHHHHHHHCCCCCEEECCCCCCCCCCC
TPAEREGAEIDIKYSGYLARQQSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVK
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
PMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP
CCCCCCHHHCCCCCCCCCEEEEEEEEHHHHHHHCCCCCCC
>Mature Secondary Structure 
TMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGP
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEEEEEEHHHHCCCCCCCCCCCC
AKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVEN
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHCC
QENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILTTGTFLGGKIWVGNKSMPAG
CCCCHHHHHHHHHHHCCCCCCEEEEHHHHCEEEEEEEEEEEECCEECCEEEECCCCCCCC
RAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDV
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEECCCCC
WVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESH
EEECCCCCEEEECCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHCCCCC
QIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQC
EEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEECCCCEEEECCCCCHHH
YPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAARFVRDQEMIVFPREQSYLGTL
HHHHHHHHHHCEEEECCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCEEEECCCHHHHHHH
VDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQI
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TGEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPEL
CCCHHHHHHHHCCCCHHHHHHHHHCHHHHHHCCCHHHHHHHCCCCCEEECCCCCCCCCCC
TPAEREGAEIDIKYSGYLARQQSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVK
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCC
PMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP
CCCCCCHHHCCCCCCCCCEEEEEEEEHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA