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The map label for this gene is ykcC [H]

Identifier: 75909557

GI number: 75909557

Start: 4170932

End: 4172236

Strand: Direct

Name: ykcC [H]

Synonym: Ava_3351

Alternate gene names: 75909557

Gene position: 4170932-4172236 (Clockwise)

Preceding gene: 75909556

Following gene: 75909558

Centisome position: 65.52

GC content: 32.95

Gene sequence:

>1305_bases
ATGAAAATATTTAAATTTCTGCTTGGTGGTAGTTTAGCAGCAGCACTAAATCTATTACTGATTTTTTTACTGGTTGAAAA
GCTCAACTTCAACACTCCCTTATTACGAAATATTGCCAATGTAATATCAATTGAAATTTCCTTAATATTTAGTTTTTTTG
TATACAGAACTTGGGTATGGACTGGTGGTGTTTGGAATCTTAGAGAAGTATTCTTACGTCAACTACCTCTTTATCATGTT
TCTGCTGGACTAGCAGTTTTTACGCGTGTTTTCTTGATTTTTCCGATTTTAGATTGGTTGCAGGTTAACTATGCAGTTAA
TACTGTAATAGGCGCACTTTTGAGCGCATCTATTAATTATTTTATTAGTGATAGTTTTGTATTTAAAACACCAAGAAAAC
AAAATCGAGATGATTTACAAGGAGAAATCCCTTTAGATACATATTATCCAGAAGCATTAGCTCCAGCTATATCAATCGGA
TCAAAATCAAAGCAATCTGAATCGAAAGTTGTAGATGTTTCTAAAACTATTACTACTTTATCAATAGTCATTCCAGCCTA
CAATGAAGAAGATTGCATAGTGCAAACAATACAAACTATTAGCAAAACCTTAGAAATTGAACAAATAGATTATGAAATTT
TAGTTGTTAACGATAATAGTAGGGATAGAACTGAAGAATTATTGCAGCAAATTACTTCACATAATAGTAAACTACGTTAT
GTGAATAATTATTATCCTAATGGCTTTGGCTTTGCGGTTCGCTGTGGTTTGGAGAACTTCACAGGGGATGCTGTAGCTGT
GGTTATGGCAGATAGTTCAGATGCACCAGAGGATATAGTATCCTACTTCCATAAGCTACAAGAGGGTTATGATTGCGTTT
TTGGTTCTCGCTTTATTAAAGGTGGTAAAGTAATTGATTATCCTGGTCACAAACTAGTTGTGAATCGTTTAGCAAACTTA
TTTATTCAAATCTTATTTAGTTTGAAATTTAATGATATTACTAATGCCTTTAAAGTTTATCGAAAGGAAGTAATTGAAGG
TATTTCTCCCTTAATATCTCATCACTTTAACTTAACGGTAGAATTGCCTCTTAAAGCTATAGTTAGAGGTTACTCCTTTA
CAACTATTCCTATAATTTGGAGAAATAGAACCACAGGTGTTTCTAAGCTCAAACTAAAAGAAATGGGTAGTCGATATTTG
TTTATAGTTCTCTACATTTGGTTAGAAAAACACCTGTCCCGTGGAGATTACCATCTCAGTAAAAAAAGAACTGTCGTTAA
ATCAAAGGCTGAATCGAATGGCTGA

Upstream 100 bases:

>100_bases
ACATTAGTTAATATTGAATGTTGATTAAGTTCATTGCAGAATATTATCCTTGATTAATTTTTGGGGAGTTTGAGTAAATT
TAATATGCAAAAAAACTGAT

Downstream 100 bases:

>100_bases
ACGTGTTTTAATTTTAGGAGGGGCTGGTTTTATTGGCAGTTCTTTAGCAATCAGTCTCAAACAACAGCATCCTTCATGGA
AAATCAGTTGTTTTGATAAT

Product: glycosyl transferase family protein

Products: GDP; dolichyl D-mannosyl phosphate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKIFKFLLGGSLAAALNLLLIFLLVEKLNFNTPLLRNIANVISIEISLIFSFFVYRTWVWTGGVWNLREVFLRQLPLYHV
SAGLAVFTRVFLIFPILDWLQVNYAVNTVIGALLSASINYFISDSFVFKTPRKQNRDDLQGEIPLDTYYPEALAPAISIG
SKSKQSESKVVDVSKTITTLSIVIPAYNEEDCIVQTIQTISKTLEIEQIDYEILVVNDNSRDRTEELLQQITSHNSKLRY
VNNYYPNGFGFAVRCGLENFTGDAVAVVMADSSDAPEDIVSYFHKLQEGYDCVFGSRFIKGGKVIDYPGHKLVVNRLANL
FIQILFSLKFNDITNAFKVYRKEVIEGISPLISHHFNLTVELPLKAIVRGYSFTTIPIIWRNRTTGVSKLKLKEMGSRYL
FIVLYIWLEKHLSRGDYHLSKKRTVVKSKAESNG

Sequences:

>Translated_434_residues
MKIFKFLLGGSLAAALNLLLIFLLVEKLNFNTPLLRNIANVISIEISLIFSFFVYRTWVWTGGVWNLREVFLRQLPLYHV
SAGLAVFTRVFLIFPILDWLQVNYAVNTVIGALLSASINYFISDSFVFKTPRKQNRDDLQGEIPLDTYYPEALAPAISIG
SKSKQSESKVVDVSKTITTLSIVIPAYNEEDCIVQTIQTISKTLEIEQIDYEILVVNDNSRDRTEELLQQITSHNSKLRY
VNNYYPNGFGFAVRCGLENFTGDAVAVVMADSSDAPEDIVSYFHKLQEGYDCVFGSRFIKGGKVIDYPGHKLVVNRLANL
FIQILFSLKFNDITNAFKVYRKEVIEGISPLISHHFNLTVELPLKAIVRGYSFTTIPIIWRNRTTGVSKLKLKEMGSRYL
FIVLYIWLEKHLSRGDYHLSKKRTVVKSKAESNG
>Mature_434_residues
MKIFKFLLGGSLAAALNLLLIFLLVEKLNFNTPLLRNIANVISIEISLIFSFFVYRTWVWTGGVWNLREVFLRQLPLYHV
SAGLAVFTRVFLIFPILDWLQVNYAVNTVIGALLSASINYFISDSFVFKTPRKQNRDDLQGEIPLDTYYPEALAPAISIG
SKSKQSESKVVDVSKTITTLSIVIPAYNEEDCIVQTIQTISKTLEIEQIDYEILVVNDNSRDRTEELLQQITSHNSKLRY
VNNYYPNGFGFAVRCGLENFTGDAVAVVMADSSDAPEDIVSYFHKLQEGYDCVFGSRFIKGGKVIDYPGHKLVVNRLANL
FIQILFSLKFNDITNAFKVYRKEVIEGISPLISHHFNLTVELPLKAIVRGYSFTTIPIIWRNRTTGVSKLKLKEMGSRYL
FIVLYIWLEKHLSRGDYHLSKKRTVVKSKAESNG

Specific function: Unknown

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family. GtrB subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503363, Length=219, Percent_Identity=28.7671232876712, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788588, Length=217, Percent_Identity=26.7281105990783, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788692, Length=121, Percent_Identity=30.5785123966942, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71999402, Length=236, Percent_Identity=25.8474576271186, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24585265, Length=220, Percent_Identity=31.3636363636364, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.83

Molecular weight: Translated: 49370; Mature: 49370

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFKFLLGGSLAAALNLLLIFLLVEKLNFNTPLLRNIANVISIEISLIFSFFVYRTWVW
CHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGGVWNLREVFLRQLPLYHVSAGLAVFTRVFLIFPILDWLQVNYAVNTVIGALLSASINY
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISDSFVFKTPRKQNRDDLQGEIPLDTYYPEALAPAISIGSKSKQSESKVVDVSKTITTL
EECCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHEEHHHHHEEE
SIVIPAYNEEDCIVQTIQTISKTLEIEQIDYEILVVNDNSRDRTEELLQQITSHNSKLRY
EEEEECCCCCHHHHHHHHHHHHHHEEEEECEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
VNNYYPNGFGFAVRCGLENFTGDAVAVVMADSSDAPEDIVSYFHKLQEGYDCVFGSRFIK
ECCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCC
GGKVIDYPGHKLVVNRLANLFIQILFSLKFNDITNAFKVYRKEVIEGISPLISHHFNLTV
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
ELPLKAIVRGYSFTTIPIIWRNRTTGVSKLKLKEMGSRYLFIVLYIWLEKHLSRGDYHLS
EECHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHH
KKRTVVKSKAESNG
HHHHHHHHHCCCCC
>Mature Secondary Structure
MKIFKFLLGGSLAAALNLLLIFLLVEKLNFNTPLLRNIANVISIEISLIFSFFVYRTWVW
CHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGGVWNLREVFLRQLPLYHVSAGLAVFTRVFLIFPILDWLQVNYAVNTVIGALLSASINY
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FISDSFVFKTPRKQNRDDLQGEIPLDTYYPEALAPAISIGSKSKQSESKVVDVSKTITTL
EECCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHEEHHHHHEEE
SIVIPAYNEEDCIVQTIQTISKTLEIEQIDYEILVVNDNSRDRTEELLQQITSHNSKLRY
EEEEECCCCCHHHHHHHHHHHHHHEEEEECEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
VNNYYPNGFGFAVRCGLENFTGDAVAVVMADSSDAPEDIVSYFHKLQEGYDCVFGSRFIK
ECCCCCCCCCEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHCC
GGKVIDYPGHKLVVNRLANLFIQILFSLKFNDITNAFKVYRKEVIEGISPLISHHFNLTV
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
ELPLKAIVRGYSFTTIPIIWRNRTTGVSKLKLKEMGSRYLFIVLYIWLEKHLSRGDYHLS
EECHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHH
KKRTVVKSKAESNG
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GDPmannose; dolichyl phosphate

Specific reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]