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The map label for this gene is xerD [H]

Identifier: 75909304

GI number: 75909304

Start: 3850251

End: 3851186

Strand: Direct

Name: xerD [H]

Synonym: Ava_3096

Alternate gene names: 75909304

Gene position: 3850251-3851186 (Clockwise)

Preceding gene: 75909303

Following gene: 75909305

Centisome position: 60.48

GC content: 47.44

Gene sequence:

>936_bases
ATGACAACCACTCTCACCATCCATGAACCACAGGTAGTTATACCTAATAGCCTACCTATAACCTACAGTGAAGACACTAC
CACAACAGAACGAGTCATAGAGTTGTGGTTGGTTGGGTTAAGTCGAACGACACGAGAACAATACAGCCGTGACATGAGGC
AGTTTAGAGCGTTCGTCAAGTTGGACGACATTCGTATCATCTCACCGATGACGTTCATCGCCTACGCCCAACACCTAGAA
CAGACGTATGCTGTTGCCACTACTCGACGTAAGTTAGCATCGTTGTCTAGTTTCTGTTCGTTCGCTGTCCGTCTGGGGTT
TCTGGCTGCAAACCCAATGGCTGCTGTCCGTAAGCCAAAAGCATCGACCACATTAGCGGGTAAGTCTTTAACACAACAAC
AGGTGTTCAGGATGCTAGATAGAACAGATGACCACCGCAACAGGTGTTTGTTAAAGGTGTTGTACAGTCTGGGGTTGCGT
GTAAGTGAAGCTGTTGGTTTACGTTGGTCAGACTTTACTGAGGTCAACCCCACCAAGACAACCGTCAGTGTATTGGGTAA
AGGTGGTAAATATCGAACGCTGGTTGTACCTCAGTCAGTTTGGTTGGAGTTAACCGAGTTGCGAACAAACCAACAGCACA
ACGGACAGAATGACTACGTGTTTCAGTCATATAGCAACCGTCATCGTAAGCAGTCAGGTAAACAACTCGACCGTTGCAAC
GCATCCAAGATAGTTAAAGCCTGTGCCGTTGCTGTTGGGTTGCCTGAGTCAGTGTCGGCTCACTTCCTACGTCATGCCTG
TGCGTCCCACAGTTTAGCCAACGGTGCATCTATCCAACTGGTAAAGGAAACGTTGGGTCATGCCAATATCTCTACAACAA
ACTGGTATTTGGAAGCTAACCCAGATGACTGTGCCTCACTGTACCTTAACGTTTAA

Upstream 100 bases:

>100_bases
AAAACGAATAATACTCACAGCCAACCATCATTTATAGGTTGGCTCTCTCTAACGATCTACACATCACAAAACAGTAGTTT
CGAGACACGTACACAAAGCC

Downstream 100 bases:

>100_bases
CTGTTATTGTCACCCGCGTTTACTTCAACTGTCCCATTCTCAGCTAACCATTCCTCTATTATTTGGGTTAATAACGTAGC
CTATATTATGATATGCTGTA

Product: tyrosine recombinase XerD subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTTTLTIHEPQVVIPNSLPITYSEDTTTTERVIELWLVGLSRTTREQYSRDMRQFRAFVKLDDIRIISPMTFIAYAQHLE
QTYAVATTRRKLASLSSFCSFAVRLGFLAANPMAAVRKPKASTTLAGKSLTQQQVFRMLDRTDDHRNRCLLKVLYSLGLR
VSEAVGLRWSDFTEVNPTKTTVSVLGKGGKYRTLVVPQSVWLELTELRTNQQHNGQNDYVFQSYSNRHRKQSGKQLDRCN
ASKIVKACAVAVGLPESVSAHFLRHACASHSLANGASIQLVKETLGHANISTTNWYLEANPDDCASLYLNV

Sequences:

>Translated_311_residues
MTTTLTIHEPQVVIPNSLPITYSEDTTTTERVIELWLVGLSRTTREQYSRDMRQFRAFVKLDDIRIISPMTFIAYAQHLE
QTYAVATTRRKLASLSSFCSFAVRLGFLAANPMAAVRKPKASTTLAGKSLTQQQVFRMLDRTDDHRNRCLLKVLYSLGLR
VSEAVGLRWSDFTEVNPTKTTVSVLGKGGKYRTLVVPQSVWLELTELRTNQQHNGQNDYVFQSYSNRHRKQSGKQLDRCN
ASKIVKACAVAVGLPESVSAHFLRHACASHSLANGASIQLVKETLGHANISTTNWYLEANPDDCASLYLNV
>Mature_310_residues
TTTLTIHEPQVVIPNSLPITYSEDTTTTERVIELWLVGLSRTTREQYSRDMRQFRAFVKLDDIRIISPMTFIAYAQHLEQ
TYAVATTRRKLASLSSFCSFAVRLGFLAANPMAAVRKPKASTTLAGKSLTQQQVFRMLDRTDDHRNRCLLKVLYSLGLRV
SEAVGLRWSDFTEVNPTKTTVSVLGKGGKYRTLVVPQSVWLELTELRTNQQHNGQNDYVFQSYSNRHRKQSGKQLDRCNA
SKIVKACAVAVGLPESVSAHFLRHACASHSLANGASIQLVKETLGHANISTTNWYLEANPDDCASLYLNV

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=285, Percent_Identity=29.8245614035088, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789261, Length=300, Percent_Identity=30.6666666666667, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790768, Length=165, Percent_Identity=27.8787878787879, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34884; Mature: 34753

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLTIHEPQVVIPNSLPITYSEDTTTTERVIELWLVGLSRTTREQYSRDMRQFRAFVK
CCCEEEEECCCEECCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LDDIRIISPMTFIAYAQHLEQTYAVATTRRKLASLSSFCSFAVRLGFLAANPMAAVRKPK
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
ASTTLAGKSLTQQQVFRMLDRTDDHRNRCLLKVLYSLGLRVSEAVGLRWSDFTEVNPTKT
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHH
TVSVLGKGGKYRTLVVPQSVWLELTELRTNQQHNGQNDYVFQSYSNRHRKQSGKQLDRCN
HHHHHCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHCHHHHHCC
ASKIVKACAVAVGLPESVSAHFLRHACASHSLANGASIQLVKETLGHANISTTNWYLEAN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECC
PDDCASLYLNV
CCCHHHEEECC
>Mature Secondary Structure 
TTTLTIHEPQVVIPNSLPITYSEDTTTTERVIELWLVGLSRTTREQYSRDMRQFRAFVK
CCEEEEECCCEECCCCCCEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LDDIRIISPMTFIAYAQHLEQTYAVATTRRKLASLSSFCSFAVRLGFLAANPMAAVRKPK
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
ASTTLAGKSLTQQQVFRMLDRTDDHRNRCLLKVLYSLGLRVSEAVGLRWSDFTEVNPTKT
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCHH
TVSVLGKGGKYRTLVVPQSVWLELTELRTNQQHNGQNDYVFQSYSNRHRKQSGKQLDRCN
HHHHHCCCCCEEEEEECHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHCHHHHHCC
ASKIVKACAVAVGLPESVSAHFLRHACASHSLANGASIQLVKETLGHANISTTNWYLEAN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEEECC
PDDCASLYLNV
CCCHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]