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The map label for this gene is kch [C]

Identifier: 75909065

GI number: 75909065

Start: 3542038

End: 3543723

Strand: Direct

Name: kch [C]

Synonym: Ava_2853

Alternate gene names: 75909065

Gene position: 3542038-3543723 (Clockwise)

Preceding gene: 75909061

Following gene: 75909067

Centisome position: 55.64

GC content: 44.07

Gene sequence:

>1686_bases
ATGAAACCTCGAATTATTGTTTGTGGCTTAGGACGAACTGGATATAAAATCTTCCGTTTGCTGAGACAGCAAGGTGCGTT
TGTAGTAGGTATTCATCACAAACCCATCCCTGGCGAAGCTGGGGGAGATGTAATTATTGGCAATTTACAAACGGCTGCTA
CCTTAGCAGCCGCAGGGATTCATCAAGCACAAACTTTGGTGATTGCTAGCTCGGATGATGCTGTAAATTTGTCGATTATG
ATGCAGGCAAGGGTGCTAAATCCGCATATTCGGATTATTAACCGCTTTTACAATATTAATTTAGGCGATCGCCTAGATCA
AACTCTGCCAGAACACCTGAGTATGAGTGTGATTGGATTAGCCGCACCATTATTTACTTTTGCTGCTTTAGGAAATCAAG
CAATTGGGCAGATCAAGTTATATGAGCAGACTTGGCCTGTCCAAGAAGAGTATATTGATGAAAATCATCCTTGGCTTGGT
CGTAAGTTAAGTGACCTGTGGGAGTGTCCGACACGGATGCCGATTTATTACTTACCTGTGGAAGGGGAGATGAGTTTGGT
ATCGGCGGTACTGTCTGGACAACACTTAAGAATAGGCGATCGCTTAATCGTGGGTATCCAGCCCCGTATCCGTTCTAACA
GACGATCCTTAATCAAAAAATGCCTGAAAGTTCTCACTAGTTTACGGCAATTTCAGCAACATGGACAATCGATAATTGTG
GGGGCGATCGTTTTACTGGCGATCGTTATAATTGCTACCCTCACCTATATGTCTACTGAATTGAGCTTATCTATGGTTGA
TGCGCTCTATTTTTCTGTAGGTATGATTACTGGTGCAGGTGGCAATGACAAGGTAGCGGAAAATGCTCCCAACAGTATCA
AATTATTCACTGTGGTTATGATGCTGGTTGGCGCTGTGGTAATTGGTATTTGGTATGCCATGATCACAGATTTTATTCTG
GGTACACGCTTCAAGCAGTTTTGGGATGCAGCCCGGATTCCCCTGCGTCATCACTATATTGTCTGTGGTTTAAGCGGTGT
TGGTAGTAAAATTGTTCAGCAACTTCATACCAGTGGTTATGAAGTGGTAGTGATTGAAACTGACTCCAACAATAAATACG
TCAATTCTGTACGTGGGTTAGGTATTCCCGTAATTCAAGGCGATGCCAGTTTCCGTACCACCCTCAAAACCAGCAATATA
GATTCTGCGGCCGCCGTGCTAGCTGTAACCAATAATGATGCTACTAACCTAGAGATCGCCCTAAAAGCTAAAGGTTTAGC
CCCTAAGATTCCCGTAATTGTCCACTATGCCGACCCTGATTTTGCAGGTATAGCGCAACAAGTATTTGACTTTGAAGCGG
TATTAAGTTCAGCAGAATTGGCAGCACCAGCCTTTGCGGCGGCGGCTTTGGGCGGACGTATTTTGGGTAACGGCATCACC
GCAGATAAACTTTGGGTAGCATTTGCCACTTTAATTACGCCGTCACATCCTTTTTGTGGTCATGTGGTCAAAGATATAGC
CATGTCGGCTGACTTTGTGCCTTTATATGTAGAAGCTAATGGTCAAAGGGTTCACGGCTGGAACTTATTAGCAACATACC
TGAGGGAAGGCGATGTTTTATATTTAACAATGCCAGCAAATCAGCTATATAAATTGTGGCGTGACGAACGGGCGTGTAAT
GCCTAG

Upstream 100 bases:

>100_bases
GTAACGTGTTTTCAGTTACAGTTATGCCGGATGCAATTAAGCCACAATGTTGATTAATCAATAGAAGTGCAGCCCTACCT
ATAAACGATGCTGCTGTCAC

Downstream 100 bases:

>100_bases
TTTGAGGGATTGGGGAACAATACGCTTCGGATAAGCAGGGGAGGAAAGGAGTTTATTTTCATAATTTTTCTCTTCCTCTG
CTTCTCTTCTCCCCTGACTT

Product: TrkA-domain-containing protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: MjK2 [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGIHQAQTLVIASSDDAVNLSIM
MQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGLAAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLG
RKLSDLWECPTRMPIYYLPVEGEMSLVSAVLSGQHLRIGDRLIVGIQPRIRSNRRSLIKKCLKVLTSLRQFQQHGQSIIV
GAIVLLAIVIIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVMMLVGAVVIGIWYAMITDFIL
GTRFKQFWDAARIPLRHHYIVCGLSGVGSKIVQQLHTSGYEVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNI
DSAAAVLAVTNNDATNLEIALKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
ADKLWVAFATLITPSHPFCGHVVKDIAMSADFVPLYVEANGQRVHGWNLLATYLREGDVLYLTMPANQLYKLWRDERACN
A

Sequences:

>Translated_561_residues
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGIHQAQTLVIASSDDAVNLSIM
MQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGLAAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLG
RKLSDLWECPTRMPIYYLPVEGEMSLVSAVLSGQHLRIGDRLIVGIQPRIRSNRRSLIKKCLKVLTSLRQFQQHGQSIIV
GAIVLLAIVIIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVMMLVGAVVIGIWYAMITDFIL
GTRFKQFWDAARIPLRHHYIVCGLSGVGSKIVQQLHTSGYEVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNI
DSAAAVLAVTNNDATNLEIALKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
ADKLWVAFATLITPSHPFCGHVVKDIAMSADFVPLYVEANGQRVHGWNLLATYLREGDVLYLTMPANQLYKLWRDERACN
A
>Mature_561_residues
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGIHQAQTLVIASSDDAVNLSIM
MQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGLAAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLG
RKLSDLWECPTRMPIYYLPVEGEMSLVSAVLSGQHLRIGDRLIVGIQPRIRSNRRSLIKKCLKVLTSLRQFQQHGQSIIV
GAIVLLAIVIIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVMMLVGAVVIGIWYAMITDFIL
GTRFKQFWDAARIPLRHHYIVCGLSGVGSKIVQQLHTSGYEVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNI
DSAAAVLAVTNNDATNLEIALKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
ADKLWVAFATLITPSHPFCGHVVKDIAMSADFVPLYVEANGQRVHGWNLLATYLREGDVLYLTMPANQLYKLWRDERACN
A

Specific function: Probable potassium channel protein [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=233, Percent_Identity=25.3218884120172, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 61187; Mature: 61187

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGI
CCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCC
HQAQTLVIASSDDAVNLSIMMQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGL
CCEEEEEEECCCCCEEEEEEEEEHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLGRKLSDLWECPTRMPIYYLPV
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEC
EGEMSLVSAVLSGQHLRIGDRLIVGIQPRIRSNRRSLIKKCLKVLTSLRQFQQHGQSIIV
CCCHHHHHHHHCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GAIVLLAIVIIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHH
MLVGAVVIGIWYAMITDFILGTRFKQFWDAARIPLRHHYIVCGLSGVGSKIVQQLHTSGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHCCCC
EVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNIDSAAAVLAVTNNDATNLEIA
EEEEEEECCCCCHHHHHCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEE
LKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
EEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCCC
ADKLWVAFATLITPSHPFCGHVVKDIAMSADFVPLYVEANGQRVHGWNLLATYLREGDVL
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECHHHHHHHHHCCCEE
YLTMPANQLYKLWRDERACNA
EEEECHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPRIIVCGLGRTGYKIFRLLRQQGAFVVGIHHKPIPGEAGGDVIIGNLQTAATLAAAGI
CCCCEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHCC
HQAQTLVIASSDDAVNLSIMMQARVLNPHIRIINRFYNINLGDRLDQTLPEHLSMSVIGL
CCEEEEEEECCCCCEEEEEEEEEHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAPLFTFAALGNQAIGQIKLYEQTWPVQEEYIDENHPWLGRKLSDLWECPTRMPIYYLPV
HHHHHHHHHHCCCCCCEEEEEECCCCCHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEEC
EGEMSLVSAVLSGQHLRIGDRLIVGIQPRIRSNRRSLIKKCLKVLTSLRQFQQHGQSIIV
CCCHHHHHHHHCCCEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
GAIVLLAIVIIATLTYMSTELSLSMVDALYFSVGMITGAGGNDKVAENAPNSIKLFTVVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHHHH
MLVGAVVIGIWYAMITDFILGTRFKQFWDAARIPLRHHYIVCGLSGVGSKIVQQLHTSGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHCCCC
EVVVIETDSNNKYVNSVRGLGIPVIQGDASFRTTLKTSNIDSAAAVLAVTNNDATNLEIA
EEEEEEECCCCCHHHHHCCCCCEEEECCCCEEEEEECCCCCCCEEEEEEECCCCCCEEEE
LKAKGLAPKIPVIVHYADPDFAGIAQQVFDFEAVLSSAELAAPAFAAAALGGRILGNGIT
EEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEECCCCC
ADKLWVAFATLITPSHPFCGHVVKDIAMSADFVPLYVEANGQRVHGWNLLATYLREGDVL
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECHHHHHHHHHCCCEE
YLTMPANQLYKLWRDERACNA
EEEECHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]