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The map label for this gene is yggV [C]

Identifier: 75908585

GI number: 75908585

Start: 2948648

End: 2949238

Strand: Direct

Name: yggV [C]

Synonym: Ava_2368

Alternate gene names: 75908585

Gene position: 2948648-2949238 (Clockwise)

Preceding gene: 75908584

Following gene: 75908589

Centisome position: 46.32

GC content: 45.85

Gene sequence:

>591_bases
ATGACTAAAATCCTCGTAGTAGCTACAAGTAACTCAGGTAAGTTGCGGGAAATGCAGGCTTATCTGGCAAATACCGACTG
GAAATTAACTCTGAAGCCGCCAGAATTAGACGTTGAAGAGACAGGTGATACCTTTGCTGCCAATGCTTGTCTCAAAGCCT
CTGAGGTTGCTAAAGCTACAGGAAACTGGGCGATCGCTGATGACTCTGGTTTACAAGTCGATGCCCTCAATGGCGTTCCT
GGGGTATATTCTGCCCGTTATGGCAAAACCGATTCAGAGAGAATTTCTCGGTTACTAAAAGAATTAGATGGCGAAGTTAA
CCGAAAAGCGCAGTTTGTATGTGTCGTGGCGATCGCCTCTCCTGATGGAGCGATCACCCTGCAAGCAGAAGGTATTTGTC
GTGGCGAAATTCTCCATGCACCCCGTGGTAGCGGTGGTTTCGGATATGATCCGATTTTTTATGTTACCGAAAAGCAGTTA
ACTTTTGCCGAGATGACACCAGAATTGAAGAAATCTGTCAGCCATCGAGGAAAAGCTTTTGCGGCTTTACTCCCTAAAAT
GGCAACAGTGCTGAGTTCAAGTTCTGAATAA

Upstream 100 bases:

>100_bases
GGCAGAGTAAGATTTAGCTAATAGTCAATAGTTAATAGTCCATAGTCCAAAAGCTCTATTAACTGTTGACTGTTGACCAC
TGACCGTTGACTATTGACCA

Downstream 100 bases:

>100_bases
AATATAGACTTACCATAATGGGATGGTAAGCCTAAAATAGTCGAATAGAAAATGTTTGTGGTTACTTATAAATCTAACGC
TCAGCTTGAGCCTTGCTGCA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MTKILVVATSNSGKLREMQAYLANTDWKLTLKPPELDVEETGDTFAANACLKASEVAKATGNWAIADDSGLQVDALNGVP
GVYSARYGKTDSERISRLLKELDGEVNRKAQFVCVVAIASPDGAITLQAEGICRGEILHAPRGSGGFGYDPIFYVTEKQL
TFAEMTPELKKSVSHRGKAFAALLPKMATVLSSSSE

Sequences:

>Translated_196_residues
MTKILVVATSNSGKLREMQAYLANTDWKLTLKPPELDVEETGDTFAANACLKASEVAKATGNWAIADDSGLQVDALNGVP
GVYSARYGKTDSERISRLLKELDGEVNRKAQFVCVVAIASPDGAITLQAEGICRGEILHAPRGSGGFGYDPIFYVTEKQL
TFAEMTPELKKSVSHRGKAFAALLPKMATVLSSSSE
>Mature_195_residues
TKILVVATSNSGKLREMQAYLANTDWKLTLKPPELDVEETGDTFAANACLKASEVAKATGNWAIADDSGLQVDALNGVPG
VYSARYGKTDSERISRLLKELDGEVNRKAQFVCVVAIASPDGAITLQAEGICRGEILHAPRGSGGFGYDPIFYVTEKQLT
FAEMTPELKKSVSHRGKAFAALLPKMATVLSSSSE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=193, Percent_Identity=44.0414507772021, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17556833, Length=178, Percent_Identity=30.3370786516854, Blast_Score=67, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6322529, Length=187, Percent_Identity=34.2245989304813, Blast_Score=88, Evalue=8e-19,
Organism=Drosophila melanogaster, GI19920712, Length=184, Percent_Identity=31.5217391304348, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 20985; Mature: 20854

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILVVATSNSGKLREMQAYLANTDWKLTLKPPELDVEETGDTFAANACLKASEVAKAT
CCEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCHHHCCCEEEHHHHHHHHHHHHCC
GNWAIADDSGLQVDALNGVPGVYSARYGKTDSERISRLLKELDGEVNRKAQFVCVVAIAS
CCEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEC
PDGAITLQAEGICRGEILHAPRGSGGFGYDPIFYVTEKQLTFAEMTPELKKSVSHRGKAF
CCCEEEEEECCCCCCEEEECCCCCCCCCCCCEEEEECCCEEHHHCCHHHHHHHHHCCHHH
AALLPKMATVLSSSSE
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKILVVATSNSGKLREMQAYLANTDWKLTLKPPELDVEETGDTFAANACLKASEVAKAT
CEEEEEEECCCCCHHHHHHHHCCCCCEEEECCCCCCHHHCCCEEEHHHHHHHHHHHHCC
GNWAIADDSGLQVDALNGVPGVYSARYGKTDSERISRLLKELDGEVNRKAQFVCVVAIAS
CCEEEECCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEEEEC
PDGAITLQAEGICRGEILHAPRGSGGFGYDPIFYVTEKQLTFAEMTPELKKSVSHRGKAF
CCCEEEEEECCCCCCEEEECCCCCCCCCCCCEEEEECCCEEHHHCCHHHHHHHHHCCHHH
AALLPKMATVLSSSSE
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]