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The map label for this gene is yggW [C]

Identifier: 75908440

GI number: 75908440

Start: 2764048

End: 2765238

Strand: Direct

Name: yggW [C]

Synonym: Ava_2223

Alternate gene names: 75908440

Gene position: 2764048-2765238 (Clockwise)

Preceding gene: 75908435

Following gene: 75908441

Centisome position: 43.42

GC content: 43.32

Gene sequence:

>1191_bases
ATGCAAAAAGTTAATGTTCCTAGCCTCGCTAGTTCTGCTTATGTACATATTCCCTTTTGCAGAAGGCGGTGCTTTTATTG
TGACTTCCCGATATTTGTTGTCGGCGATCGCCAACGTGGTGAAACATCTGTTACCATCTCCGGGTATGTGGATACTCTCT
GTGAAGAAATTGCCATTACACCAGTTTTTGGTCAACCCCTCCAGACCATATTTTTCGGCGGTGGTACGCCTTCGCTGTTA
TCTACAGCACAATTAGCACAAATACTAGGAACCCTAGATAAGCGGTTTGGGATTGTGCCTGATGCAGAAATTTCGATGGA
AATTGATCCAGGTACATTTGATCTAGCACACATCCAAGGCTATCGTAGCGTTGGTGTGAATCGGGTAAGTTTGGGTGTAC
AAGCGTTTCAAGAAGAATTGTTAAAATTAGCTGGGCGATCGCACTCGCTTAAAGATATCTTTGCAGCTATAGACTTGATT
CACCAAGTCGAGATTCCCGAATTTAGCATAGACTTAATCTCTGGGTTGCCGCATCAGTCTTTAGATCAATGGCAAGATTC
CCTAGAAACAGCCGTTAACATTGCACCCACCCATATATCTATCTATGATTTGACAATTGAGCCAGGAACAGCCTTTGGTC
GTTATTACAAACCTGGGGATAATCCCTTACCTACTGATGAAACCACAGTGAAAATGTATCAGATGGGTCAGAGGATTTTG
ACTGATGGCGGTTATGAACATTATGAAATTTCCAACTACGCCAAGCCAGGACACCAGTGTAGACATAACCGCGTGTATTG
GGAAAACTGCCCTTATTACGGCTTTGGTATGGGTGCGGCCAGCTATGTAGAAGGTAAACGCTTCACCCGTCCCCGAAAAA
CAAAGGAATATTCTCAATGGGTGCAAGAGTTGATTGCTAATCACGGTGTGATTGATTGGGAAATTACGCCAAAAGCAGAT
GTATTGTTAGAAACGTTAATGTTGGGGTTACGCTTGGCTGATGGTGTGAGTTTAGCAGCACTAACCGAGGAATTTGGCAA
GGAGAAAATACAAGAACTGCATCAATGTCTGCAACCTTATTTTACTCAAGGTTGGGTACAAGTTGTGGGTGATAGGTTGC
GGTTGAGTGATCCCGATGGTTTTTTATTTTCCAATGTGGTGTTAGCCGATTTGTTTAGTCAGTTGGGTTAA

Upstream 100 bases:

>100_bases
TGTCATTGCTACGTCAATAAACTATAGAAACCTGTAAATAAACTATTTATTTTCATTATTTCTAATTTTCCGTTAATTAA
GTTTATTCTTGTTCACAAAT

Downstream 100 bases:

>100_bases
TGACCTTTTTTGAATTCACAATCCAAAATCCGCTACTCTAAAGCTGCGCCAACAAGCCCCCACTAATTGTCTTTAATTTT
GAATTTTGCGAAAAGTTCTG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDTLCEEIAITPVFGQPLQTIFFGGGTPSLL
STAQLAQILGTLDKRFGIVPDAEISMEIDPGTFDLAHIQGYRSVGVNRVSLGVQAFQEELLKLAGRSHSLKDIFAAIDLI
HQVEIPEFSIDLISGLPHQSLDQWQDSLETAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQRIL
TDGGYEHYEISNYAKPGHQCRHNRVYWENCPYYGFGMGAASYVEGKRFTRPRKTKEYSQWVQELIANHGVIDWEITPKAD
VLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPYFTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG

Sequences:

>Translated_396_residues
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDTLCEEIAITPVFGQPLQTIFFGGGTPSLL
STAQLAQILGTLDKRFGIVPDAEISMEIDPGTFDLAHIQGYRSVGVNRVSLGVQAFQEELLKLAGRSHSLKDIFAAIDLI
HQVEIPEFSIDLISGLPHQSLDQWQDSLETAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQRIL
TDGGYEHYEISNYAKPGHQCRHNRVYWENCPYYGFGMGAASYVEGKRFTRPRKTKEYSQWVQELIANHGVIDWEITPKAD
VLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPYFTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG
>Mature_396_residues
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDTLCEEIAITPVFGQPLQTIFFGGGTPSLL
STAQLAQILGTLDKRFGIVPDAEISMEIDPGTFDLAHIQGYRSVGVNRVSLGVQAFQEELLKLAGRSHSLKDIFAAIDLI
HQVEIPEFSIDLISGLPHQSLDQWQDSLETAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQRIL
TDGGYEHYEISNYAKPGHQCRHNRVYWENCPYYGFGMGAASYVEGKRFTRPRKTKEYSQWVQELIANHGVIDWEITPKAD
VLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPYFTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=269, Percent_Identity=31.5985130111524, Blast_Score=165, Evalue=5e-41,
Organism=Escherichia coli, GI1789325, Length=303, Percent_Identity=39.6039603960396, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI87082341, Length=311, Percent_Identity=29.2604501607717, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 44341; Mature: 44341

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDTLCEEIAIT
CCCCCCCCCCCCCEEEEEHHHCCCEEECCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCC
PVFGQPLQTIFFGGGTPSLLSTAQLAQILGTLDKRFGIVPDAEISMEIDPGTFDLAHIQG
CCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEHHHHCC
YRSVGVNRVSLGVQAFQEELLKLAGRSHSLKDIFAAIDLIHQVEIPEFSIDLISGLPHQS
HHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCH
LDQWQDSLETAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQRIL
HHHHHHHHHHHHEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TDGGYEHYEISNYAKPGHQCRHNRVYWENCPYYGFGMGAASYVEGKRFTRPRKTKEYSQW
HCCCCCEEECCCCCCCCHHHHCCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHH
VQELIANHGVIDWEITPKADVLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPY
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG
HHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKVNVPSLASSAYVHIPFCRRRCFYCDFPIFVVGDRQRGETSVTISGYVDTLCEEIAIT
CCCCCCCCCCCCCEEEEEHHHCCCEEECCCEEEEECCCCCCEEEEEHHHHHHHHHHHCCC
PVFGQPLQTIFFGGGTPSLLSTAQLAQILGTLDKRFGIVPDAEISMEIDPGTFDLAHIQG
CCCCCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEHHHHCC
YRSVGVNRVSLGVQAFQEELLKLAGRSHSLKDIFAAIDLIHQVEIPEFSIDLISGLPHQS
HHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCH
LDQWQDSLETAVNIAPTHISIYDLTIEPGTAFGRYYKPGDNPLPTDETTVKMYQMGQRIL
HHHHHHHHHHHHEECCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TDGGYEHYEISNYAKPGHQCRHNRVYWENCPYYGFGMGAASYVEGKRFTRPRKTKEYSQW
HCCCCCEEECCCCCCCCHHHHCCCEEECCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHH
VQELIANHGVIDWEITPKADVLLETLMLGLRLADGVSLAALTEEFGKEKIQELHQCLQPY
HHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FTQGWVQVVGDRLRLSDPDGFLFSNVVLADLFSQLG
HHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]