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The map label for this gene is infC

Identifier: 75908259

GI number: 75908259

Start: 2520574

End: 2521107

Strand: Direct

Name: infC

Synonym: Ava_2038

Alternate gene names: 75908259

Gene position: 2520574-2521107 (Clockwise)

Preceding gene: 75908257

Following gene: 75908260

Centisome position: 39.6

GC content: 48.13

Gene sequence:

>534_bases
ATGCCTGTGATTGAGAAAAAAAGAACTCGCGATCTGCCCCAAATTAACGAACGGATCCGCTTCCCGAAAATTCGAGTCAT
TGACACTGATGGTTCCCAGCTAGGAATTCTAACTCCACAGGAAGCGCTGCAACTAGCAGAGGAGAAGGAGCTGGATCTAG
TGCTACTCAGTGACAAGGCCGACCCGCCGGTGTGTCGGATTATGGATTACGGGAAATACAAGTTCGAGCAGGAGAAGAAG
GCGCGGGAAGCTCGAAAGAAACAGCACACGGCTGATGTGAAAGAAGTGAAGATGCGCTACAAAATCGAGGAACACGACTA
CAATGTCCGTGTTAAGCAAGCAGAACGCTTCTTGAAAGATGGTGATAAAGTCAAAGCAACTGTGATGTTCCGGGGTCGAG
AGATTCAACACAGTGACCTGGCAGAAGATTTACTGAAGCGAATGGCAACGGATCTGGAACCGTTTGGTGAAGTGCAACAA
GCACCCAAAAAAGAAGGGCGAAACATGATGATGCTCATCTCGCCTAAGAAGTAA

Upstream 100 bases:

>100_bases
TCTCAGTTATTTTAGTATTGTGCTGCTTAGGCAGACCAATCAAAACAAAGCAATCAAGTCCACATTACATTACTTAACAA
AGAAGCTCCCACAAATCATA

Downstream 100 bases:

>100_bases
TACCCTAAGTATTCTTGTAACCAAGTAATCCACCACTGAAAATATCAAAACGGCTTCACCGTCGTTGAAATTAATTGCAA
TTTGATAGTCCTGAACTCTG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDLVLLSDKADPPVCRIMDYGKYKFEQEKK
AREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGEVQQ
APKKEGRNMMMLISPKK

Sequences:

>Translated_177_residues
MPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDLVLLSDKADPPVCRIMDYGKYKFEQEKK
AREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGEVQQ
APKKEGRNMMMLISPKK
>Mature_176_residues
PVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDLVLLSDKADPPVCRIMDYGKYKFEQEKKA
REARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGEVQQA
PKKEGRNMMMLISPKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=165, Percent_Identity=46.0606060606061, Blast_Score=137, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_ANAVT (Q3MBH6)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_322555.1
- ProteinModelPortal:   Q3MBH6
- STRING:   Q3MBH6
- GeneID:   3680979
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_2038
- eggNOG:   COG0290
- HOGENOM:   HBG744268
- OMA:   KQMKFRL
- ProtClustDB:   PRK00028
- BioCyc:   AVAR240292:AVA_2038-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20750; Mature: 20619

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDLVLLSDKA
CCCCCCCHHCCCHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHCCCCEEEECCCC
DPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKD
CCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCEEHHHHHHHHHC
GDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGEVQQAPKKEGRNMMMLISPKK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHCHHHCCCCEEEEEECCC
>Mature Secondary Structure 
PVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDLVLLSDKA
CCCCCCHHCCCHHHHHHCCCCEEEEEECCCCEEECCCHHHHHHHHHHCCCCEEEECCCC
DPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKD
CCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCEEHHHHHHHHHC
GDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGEVQQAPKKEGRNMMMLISPKK
CCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHCHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA