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The map label for this gene is trpB2 [H]

Identifier: 75908132

GI number: 75908132

Start: 2373469

End: 2374710

Strand: Direct

Name: trpB2 [H]

Synonym: Ava_1911

Alternate gene names: 75908132

Gene position: 2373469-2374710 (Clockwise)

Preceding gene: 75908129

Following gene: 75908133

Centisome position: 37.29

GC content: 48.63

Gene sequence:

>1242_bases
GTGACTACCACTCCCCTTTCTCCAAGTACCCCCTCAAATGCTCAGGTTCCCGATATCCAAGGACGCTTTGGACGCTTTGG
CGGTAAGTATGTGCCGGAAACCTTGATGCCGGCTTTGGCTGAATTAGAAACAGCTTATCAAAAATACCGCCATGACCCTG
GTTTTCAAGCAGAACTGCAACAATTATTACGGGACTACGTAGGACGTGCGACACCGTTGTATTTTGCAGAACGCCTCACT
GCCCATTATGCCCGACCAGATGGTACAGGAGCGCAAATTTACTTAAAACGCGAAGATTTAAATCATACAGGTGCTCATAA
AATTAATAACGCCCTTGGTCAAGTATTATTAGCCAAGCGCATGGGTAAGCAGCGCATTATTGCCGAAACCGGTGCTGGAC
AACATGGTGTAGCAACGGCTACAGTTTGCGCTCGGTTTGGGTTGGAATGTGTGATTTATATGGGTGTTCACGATATGGAA
CGCCAAGCTTTGAATGTGTTTAGAATGCGGCTGATGGGGGCTGAAGTTCGTCCAGTAGAGGCTGGGACTGGAACTCTCAA
GGACGCTACATCTGAGGCAATTCGGGATTGGGTGACGAATGTGGAAACTACTCACTACATTTTGGGTTCCGTCGCCGGGC
CTCATCCTTACCCAATGATGGTACGGGATTTTCATGCAGTCATTGGGCAAGAAACTCGCGCTCAAGCTTTGGAAAAATGG
GGTGGTTTACCCGATATTCTCTTGGCTTGTGTGGGTGGCGGGTCTAATGCGATGGGCTTATTTTACGAGTTTGTGAATGA
GTCATCCATTAGGTTAATTGGAGTAGAAGCAGCTGGGGAAGGTGTCAATACAGAAAAGCACGCTGCCACCTTGACAAAAG
GGCGCGTTGGTGTATTACACGGGGCGATGAGTTATCTGCTGCAAGATGAGGATGGCCAGGTAATTGAAGCGCACTCGATT
AGCGCGGGGTTAGATTACCCTGGTGTGGGGCCAGAACACAGCTATTTGAAGGATGTTGGTCGTGCAGAATATTACAGTGT
GACGGATGAGCAAGCTTTGGCTGCGTTCCAGCGATTATCCCGCTTGGAAGGAATTATCCCAGCCCTGGAAACAGCCCATG
CGATCGCCTACTTAGAAACCCTCTGTCCTCAACTTGACGGTAGCCCCCGCATTATTATCAACTGCTCTGGACGCGGTGAT
AAAGATGTCCAAACTGTAGCTAAGTTTTTAATCCCACAATAA

Upstream 100 bases:

>100_bases
CGAACTAGTTTAATGTCTTTCTTGTGAAGCTACACTGTATTATCTGTGCCTCAGACTTTCCTATAATAATTAAGTCTATC
CCATCATCAAAAATCATTCC

Downstream 100 bases:

>100_bases
ATCTATCTAAAGATAGATATTTTGTTAAAGATTTATAAATTTACGCAGGCTGTTTTGCAGCATTTTTCGGGAAAATTTAG
CGAAAAATCAGACTTATAGG

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTTTPLSPSTPSNAQVPDIQGRFGRFGGKYVPETLMPALAELETAYQKYRHDPGFQAELQQLLRDYVGRATPLYFAERLT
AHYARPDGTGAQIYLKREDLNHTGAHKINNALGQVLLAKRMGKQRIIAETGAGQHGVATATVCARFGLECVIYMGVHDME
RQALNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRAQALEKW
GGLPDILLACVGGGSNAMGLFYEFVNESSIRLIGVEAAGEGVNTEKHAATLTKGRVGVLHGAMSYLLQDEDGQVIEAHSI
SAGLDYPGVGPEHSYLKDVGRAEYYSVTDEQALAAFQRLSRLEGIIPALETAHAIAYLETLCPQLDGSPRIIINCSGRGD
KDVQTVAKFLIPQ

Sequences:

>Translated_413_residues
MTTTPLSPSTPSNAQVPDIQGRFGRFGGKYVPETLMPALAELETAYQKYRHDPGFQAELQQLLRDYVGRATPLYFAERLT
AHYARPDGTGAQIYLKREDLNHTGAHKINNALGQVLLAKRMGKQRIIAETGAGQHGVATATVCARFGLECVIYMGVHDME
RQALNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRAQALEKW
GGLPDILLACVGGGSNAMGLFYEFVNESSIRLIGVEAAGEGVNTEKHAATLTKGRVGVLHGAMSYLLQDEDGQVIEAHSI
SAGLDYPGVGPEHSYLKDVGRAEYYSVTDEQALAAFQRLSRLEGIIPALETAHAIAYLETLCPQLDGSPRIIINCSGRGD
KDVQTVAKFLIPQ
>Mature_412_residues
TTTPLSPSTPSNAQVPDIQGRFGRFGGKYVPETLMPALAELETAYQKYRHDPGFQAELQQLLRDYVGRATPLYFAERLTA
HYARPDGTGAQIYLKREDLNHTGAHKINNALGQVLLAKRMGKQRIIAETGAGQHGVATATVCARFGLECVIYMGVHDMER
QALNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRAQALEKWG
GLPDILLACVGGGSNAMGLFYEFVNESSIRLIGVEAAGEGVNTEKHAATLTKGRVGVLHGAMSYLLQDEDGQVIEAHSIS
AGLDYPGVGPEHSYLKDVGRAEYYSVTDEQALAAFQRLSRLEGIIPALETAHAIAYLETLCPQLDGSPRIIINCSGRGDK
DVQTVAKFLIPQ

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=56.8123393316195, Blast_Score=452, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6321412, Length=390, Percent_Identity=58.974358974359, Blast_Score=470, Evalue=1e-133,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 44907; Mature: 44775

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTPLSPSTPSNAQVPDIQGRFGRFGGKYVPETLMPALAELETAYQKYRHDPGFQAELQ
CCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QLLRDYVGRATPLYFAERLTAHYARPDGTGAQIYLKREDLNHTGAHKINNALGQVLLAKR
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
MGKQRIIAETGAGQHGVATATVCARFGLECVIYMGVHDMERQALNVFRMRLMGAEVRPVE
CCCHHEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEC
AGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRAQALEKW
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
GGLPDILLACVGGGSNAMGLFYEFVNESSIRLIGVEAAGEGVNTEKHAATLTKGRVGVLH
CCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHH
GAMSYLLQDEDGQVIEAHSISAGLDYPGVGPEHSYLKDVGRAEYYSVTDEQALAAFQRLS
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHCCCCHHHHHHHHHHHH
RLEGIIPALETAHAIAYLETLCPQLDGSPRIIINCSGRGDKDVQTVAKFLIPQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
TTTPLSPSTPSNAQVPDIQGRFGRFGGKYVPETLMPALAELETAYQKYRHDPGFQAELQ
CCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHH
QLLRDYVGRATPLYFAERLTAHYARPDGTGAQIYLKREDLNHTGAHKINNALGQVLLAKR
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHH
MGKQRIIAETGAGQHGVATATVCARFGLECVIYMGVHDMERQALNVFRMRLMGAEVRPVE
CCCHHEEEECCCCCCCHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCEEC
AGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGQETRAQALEKW
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHH
GGLPDILLACVGGGSNAMGLFYEFVNESSIRLIGVEAAGEGVNTEKHAATLTKGRVGVLH
CCCHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHCCCHHHHH
GAMSYLLQDEDGQVIEAHSISAGLDYPGVGPEHSYLKDVGRAEYYSVTDEQALAAFQRLS
HHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCHHCCCCHHHHHHHHHHHH
RLEGIIPALETAHAIAYLETLCPQLDGSPRIIINCSGRGDKDVQTVAKFLIPQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]