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The map label for this gene is cobO [H]

Identifier: 75908119

GI number: 75908119

Start: 2357303

End: 2357995

Strand: Direct

Name: cobO [H]

Synonym: Ava_1898

Alternate gene names: 75908119

Gene position: 2357303-2357995 (Clockwise)

Preceding gene: 75908116

Following gene: 75908122

Centisome position: 37.03

GC content: 44.88

Gene sequence:

>693_bases
ATGAATTTGATGACAAGCGATACACCAGAAGCATTAGAATCAGATAAGGAAATTGAGCGTCTCATTGATGAAATAATGGC
ATCAACCCAAAACCTTTCTGATGAACAATACCGCACCAAAATGCAGCGCCGCAAGGAAGTACAAGAGCGCCGCATATCTC
AAGCTGTGCCAGAAAAAGGGTTAATTATTGTTAATACTGGTAACGGTAAAGGCAAAACCACCGCAGCACTAGGTATGGTA
TTACGATCGCTCGGTCATGGGTATAAAGTAGCGATCGTCCAGTTCATCAAGGGTGGTTGGGAACCTTCAGAAAAAAGCGT
GTTTAGCTACTGGGAAGACCAAATCGAGTTTCACGCAATGGGAGAAGGCTTTACTTGGGACACCCAAGACCGCGATCGCG
ACATTGACAAAGCTCAAGCCGCATGGGAAAAATCATTAGAGTTCATCCTTGATCCTAAGTACCAGTTAGTTTTGTTAGAT
GAAATTAATATTGCCCTGAAAATGGGCTATTTAAGCGTAGATGAGGTGCTGGCTGGCTTGGCACGTAAACCCACAAGTAA
GCACGTAATTCTTACAGGTAGAGGCGCACCAGCCGCCCTCATTGAACGCGCAGACTTAGTTACAGAAATGACACTGATTA
AGCACCCTTTCCGTGATCAAAACGTTAAGGCGCAGCCAGGGATTGAGTATTAG

Upstream 100 bases:

>100_bases
TTTTTCTTTTCTCTGCCAGATTCCCCTCAAGTTCTCATCGATCTAAACACAAGTTTTTCTTGGGTTTGTTAGTTGTAACA
TTTATTTTCTGTATTTCCTG

Downstream 100 bases:

>100_bases
TCGTGTATACACGTTGTATACAACACCCTGTTTTTGTAGAGACGTTGTATACAACATCTCTACTGACTACACATTTGTAG
AATGCGGCGATCGCCAGGAC

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MNLMTSDTPEALESDKEIERLIDEIMASTQNLSDEQYRTKMQRRKEVQERRISQAVPEKGLIIVNTGNGKGKTTAALGMV
LRSLGHGYKVAIVQFIKGGWEPSEKSVFSYWEDQIEFHAMGEGFTWDTQDRDRDIDKAQAAWEKSLEFILDPKYQLVLLD
EINIALKMGYLSVDEVLAGLARKPTSKHVILTGRGAPAALIERADLVTEMTLIKHPFRDQNVKAQPGIEY

Sequences:

>Translated_230_residues
MNLMTSDTPEALESDKEIERLIDEIMASTQNLSDEQYRTKMQRRKEVQERRISQAVPEKGLIIVNTGNGKGKTTAALGMV
LRSLGHGYKVAIVQFIKGGWEPSEKSVFSYWEDQIEFHAMGEGFTWDTQDRDRDIDKAQAAWEKSLEFILDPKYQLVLLD
EINIALKMGYLSVDEVLAGLARKPTSKHVILTGRGAPAALIERADLVTEMTLIKHPFRDQNVKAQPGIEY
>Mature_230_residues
MNLMTSDTPEALESDKEIERLIDEIMASTQNLSDEQYRTKMQRRKEVQERRISQAVPEKGLIIVNTGNGKGKTTAALGMV
LRSLGHGYKVAIVQFIKGGWEPSEKSVFSYWEDQIEFHAMGEGFTWDTQDRDRDIDKAQAAWEKSLEFILDPKYQLVLLD
EINIALKMGYLSVDEVLAGLARKPTSKHVILTGRGAPAALIERADLVTEMTLIKHPFRDQNVKAQPGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=199, Percent_Identity=44.7236180904523, Blast_Score=178, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 26010; Mature: 26010

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLMTSDTPEALESDKEIERLIDEIMASTQNLSDEQYRTKMQRRKEVQERRISQAVPEKG
CCCCCCCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
LIIVNTGNGKGKTTAALGMVLRSLGHGYKVAIVQFIKGGWEPSEKSVFSYWEDQIEFHAM
EEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEC
GEGFTWDTQDRDRDIDKAQAAWEKSLEFILDPKYQLVLLDEINIALKMGYLSVDEVLAGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCHHHHHHHH
ARKPTSKHVILTGRGAPAALIERADLVTEMTLIKHPFRDQNVKAQPGIEY
HCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLMTSDTPEALESDKEIERLIDEIMASTQNLSDEQYRTKMQRRKEVQERRISQAVPEKG
CCCCCCCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
LIIVNTGNGKGKTTAALGMVLRSLGHGYKVAIVQFIKGGWEPSEKSVFSYWEDQIEFHAM
EEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHEEEEC
GEGFTWDTQDRDRDIDKAQAAWEKSLEFILDPKYQLVLLDEINIALKMGYLSVDEVLAGL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCHHHHHHHH
ARKPTSKHVILTGRGAPAALIERADLVTEMTLIKHPFRDQNVKAQPGIEY
HCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]