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The map label for this gene is rbcR

Identifier: 75907970

GI number: 75907970

Start: 2182610

End: 2183623

Strand: Direct

Name: rbcR

Synonym: Ava_1749

Alternate gene names: 75907970

Gene position: 2182610-2183623 (Clockwise)

Preceding gene: 75907965

Following gene: 75907972

Centisome position: 34.29

GC content: 44.18

Gene sequence:

>1014_bases
ATGTCTGACCTTCCTTTCACTTTAGATCAGTTACGCATTCTCAAAGCGATCGCCGTAGAAGGGAGCTTCAAACGCGCCGC
TGATAGTCTTTATGTCTCCCAACCTGCCGTGAGTTTGCAAGTGCAGAATTTAGAACGGCAGTTGGATGTCCCTTTATTTG
ACCGTGGCGGCCGTCGCGCACAATTAACCGAAGCAGGACATCTACTATTGAATTACGGTGAAAAAATTCTCAGTTTGTGC
CAAGAAACTTGCCGCGCTATTGAGGATTTACAAAATCTCCAAGGAGGTACTTTAATTGTTGGTGCTTCTCAAACTACTGG
AACATACCTGCTGCCGAAAATGATTGGGATGTTCCGACAGAAGTACCCTGATGTGGCAGTACAACTGCACGTCCATTCGA
CTCGGCGCACAGCTTGGAGTGTGGCTAACGGGCAAGTGGATTTGGCAATTATCGGGGGGGAAATTCCTGGGGAACTGACG
GAGTCTTTGGAAATTATTCCCTATGCCGAAGATGAACTGGCCCTTATTCTCCCAGTGTTTCACCCCTTTACCAAACAGGA
AACAATTCAAAAAGAAGATTTATACAAACTACAATTCATTACTTTAGATTCTCAATCAACAATACGCAAAGTTATCGATC
AAGTCCTATCTCGCAGTGAGATTGATACTAGGCGGTTTAAGATTGAAATGGAGTTAAATTCCATTGAGGCGATTAAAAAT
GCTGTACAGTCGGGTTTAGGTGCAGCTTTTGTTTCCACTAGTGCGATCGCTAAAGAATTACAGATGGGTGTACTCCACTG
CACCCCCATTGATGGCGTAGTCATCAAACGGACACTGTGGCTAATTTTCAATCCTAATCGTTACAGATCCAAAGCAGCAG
AAGCTTTTAGCCAAGAGATATTACCGCAGTTCGCCACTCCTGACTGGAATCAAGATGTGTTAAAACTGGTGCAAAAAAAA
CTAGTGGTAAATGTACTAGATGCAGCCATCCCCAATACTTCCGATGATGGCTAA

Upstream 100 bases:

>100_bases
TGAGTATTTTATTCACGCCGTCGTGTACTAATAGTTGCAAAGCTATAAAACATGATTTATTGCTAACGTTGCTCCTTTCA
AAGTTCGTGGGTTGAGCCTT

Downstream 100 bases:

>100_bases
CATTTGGTCATTCGTGAGGCAAAGTAATCTTCTCCTCAACAGAAATGCTGGCGCTACGGGATTTTTCCTTGTTGGCGCTA
GCCTACTCTACGACAATACC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLLNYGEKILSLC
QETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQKYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELT
ESLEIIPYAEDELALILPVFHPFTKQETIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKN
AVQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEILPQFATPDWNQDVLKLVQKK
LVVNVLDAAIPNTSDDG

Sequences:

>Translated_337_residues
MSDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLLNYGEKILSLC
QETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQKYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELT
ESLEIIPYAEDELALILPVFHPFTKQETIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKN
AVQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEILPQFATPDWNQDVLKLVQKK
LVVNVLDAAIPNTSDDG
>Mature_336_residues
SDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRAQLTEAGHLLLNYGEKILSLCQ
ETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQKYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELTE
SLEIIPYAEDELALILPVFHPFTKQETIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKNA
VQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEILPQFATPDWNQDVLKLVQKKL
VVNVLDAAIPNTSDDG

Specific function: Trans-acting transcriptional regulator of RuBisCO genes (rbcL and rbcS) expression

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1788481, Length=293, Percent_Identity=32.7645051194539, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI157672245, Length=301, Percent_Identity=29.2358803986711, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=27.1428571428571, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI145693105, Length=289, Percent_Identity=26.2975778546713, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1787879, Length=299, Percent_Identity=28.0936454849498, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1787530, Length=258, Percent_Identity=27.1317829457364, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788748, Length=302, Percent_Identity=29.1390728476821, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788296, Length=249, Percent_Identity=27.3092369477912, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788887, Length=197, Percent_Identity=29.9492385786802, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082132, Length=254, Percent_Identity=27.5590551181102, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788626, Length=256, Percent_Identity=29.296875, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=28.2868525896414, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788297, Length=253, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI87081904, Length=143, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787806, Length=292, Percent_Identity=23.6301369863014, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789204, Length=313, Percent_Identity=23.6421725239617, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789173, Length=304, Percent_Identity=28.2894736842105, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082024, Length=290, Percent_Identity=26.2068965517241, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786401, Length=267, Percent_Identity=29.9625468164794, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786448, Length=306, Percent_Identity=26.797385620915, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787601, Length=146, Percent_Identity=30.1369863013699, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789492, Length=72, Percent_Identity=45.8333333333333, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787949, Length=141, Percent_Identity=31.9148936170213, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): RBCR_ANAVT (Q3MCB5)

Other databases:

- EMBL:   CP000117
- RefSeq:   YP_322266.1
- ProteinModelPortal:   Q3MCB5
- STRING:   Q3MCB5
- GeneID:   3682131
- GenomeReviews:   CP000117_GR
- KEGG:   ava:Ava_1749
- NMPDR:   fig|240292.3.peg.2829
- eggNOG:   COG0583
- HOGENOM:   HBG685425
- OMA:   GLFRQKY
- PhylomeDB:   Q3MCB5
- ProtClustDB:   CLSK892696
- BioCyc:   AVAR240292:AVA_1749-MONOMER
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PRINTS:   PR00039

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate

EC number: NA

Molecular weight: Translated: 37487; Mature: 37355

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRA
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCEEEHHHHHHHCCCCCCCCCCCEE
QLTEAGHLLLNYGEKILSLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQ
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
KYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELTESLEIIPYAEDELALILPVF
CCCCEEEEEEEECCCHHHEEECCCEEEEEEECCCCCCHHHCCEEEEECCCCCEEEEEEHH
HPFTKQETIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKN
CCCCCHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHH
AVQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEI
HHHHCCCHHHHHHHHHHHHHHHCEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHH
LPQFATPDWNQDVLKLVQKKLVVNVLDAAIPNTSDDG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDLPFTLDQLRILKAIAVEGSFKRAADSLYVSQPAVSLQVQNLERQLDVPLFDRGGRRA
CCCCCHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCEEEHHHHHHHCCCCCCCCCCCEE
QLTEAGHLLLNYGEKILSLCQETCRAIEDLQNLQGGTLIVGASQTTGTYLLPKMIGMFRQ
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHH
KYPDVAVQLHVHSTRRTAWSVANGQVDLAIIGGEIPGELTESLEIIPYAEDELALILPVF
CCCCEEEEEEEECCCHHHEEECCCEEEEEEECCCCCCHHHCCEEEEECCCCCEEEEEEHH
HPFTKQETIQKEDLYKLQFITLDSQSTIRKVIDQVLSRSEIDTRRFKIEMELNSIEAIKN
CCCCCHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHH
AVQSGLGAAFVSTSAIAKELQMGVLHCTPIDGVVIKRTLWLIFNPNRYRSKAAEAFSQEI
HHHHCCCHHHHHHHHHHHHHHHCEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHH
LPQFATPDWNQDVLKLVQKKLVVNVLDAAIPNTSDDG
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA