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The map label for this gene is serB [C]

Identifier: 75676530

GI number: 75676530

Start: 2565903

End: 2566796

Strand: Direct

Name: serB [C]

Synonym: Nwi_2345

Alternate gene names: 75676530

Gene position: 2565903-2566796 (Clockwise)

Preceding gene: 75676525

Following gene: 75676537

Centisome position: 75.42

GC content: 65.88

Gene sequence:

>894_bases
ATGTCGCTCGTCGCCACGCTGATCTGCAATCCGGCCAACCCCGCGCTCGATAGCACGGTGCTGGACGGCGCGCGCGCAAT
TCTGGGCAATGCCGGTCCGGCGCAATGGCTGTGGGACGAGGTCGCGGCCGACATTCCCTTCGAAAGCACCGACTCCATCC
CGGCCATCACACAGCGCCTGCGCGAGGCGCGTGGCGATCTGCCGATCGACGTGGTGGTCCAGCCGCAGATCGGACGGCGC
AAGAAGCTGTTTCTGGCCGATATGGATTCCACCATGATCGGCCAGGAATGCATCGACGAACTCGCCGATTTCGCAGGCCT
CAAGGCGCATGTCGCAGCGATCACCGAGCGCGCCATGCGCGGCGAAATGCAATTTGAGGCGGCGTTGCGCGAACGCGTGG
CGTTGCTCAAGGGGCTTCCCGTATCCGTGGTCGACGAGGTGCTGGCAAAGCGCATCACGCCGACGCCGGGCGGGCGCGAA
CTGGTCATGACCATGCGCGCCAACGGAGCCTATACCTGCCTGATCTCCGGCGGCTTCACGCTCTTCACCGAGGCGGTAGC
CGCCCTGATCGGCTTTCACGAGAATCGCGGCAACACGCTGCTGGTCGAAAACGGAAAACTGTCAGGCACGGCCGCGGAGC
CGATCGTCGGCCGCGAGGCCAAACTCACGACCCTGATCGAATTGCGTGAGTCCTCCGGTCTCGACGGGCTGGATACGCTG
GCGGTGGGCGACGGCGCCAACGACCTCGGCATGATCCAACAGGCGGGCCTGGGCGTCGCCTATCACGCCAAGCCCGCGGT
TGCCGCGGCGGCAGCAGCCCGCATCGACCATGGCGACCTGACCGCGCTGCTGTATGCGCAGGGGTACCAGCGCGACGAGT
TCGTCAACGCATAG

Upstream 100 bases:

>100_bases
GGCAAGCGACAGCGCCAGCGCGGACTTGCCGCTCGCGGTCGGCCCTGCGATAAGCACGGCATCCGTCGCCTCCACCCCCT
CATCACGGTTCAACCCGCCC

Downstream 100 bases:

>100_bases
ACTCTATAGTGTTTTCGAGCGAAATGGATGACCTGTTCGCGTGAAGAAAACGCGTTAAAACAAGATTATAGAACCTCTTA
AACGTGGTTCCGCGAGAGAG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSLVATLICNPANPALDSTVLDGARAILGNAGPAQWLWDEVAADIPFESTDSIPAITQRLREARGDLPIDVVVQPQIGRR
KKLFLADMDSTMIGQECIDELADFAGLKAHVAAITERAMRGEMQFEAALRERVALLKGLPVSVVDEVLAKRITPTPGGRE
LVMTMRANGAYTCLISGGFTLFTEAVAALIGFHENRGNTLLVENGKLSGTAAEPIVGREAKLTTLIELRESSGLDGLDTL
AVGDGANDLGMIQQAGLGVAYHAKPAVAAAAAARIDHGDLTALLYAQGYQRDEFVNA

Sequences:

>Translated_297_residues
MSLVATLICNPANPALDSTVLDGARAILGNAGPAQWLWDEVAADIPFESTDSIPAITQRLREARGDLPIDVVVQPQIGRR
KKLFLADMDSTMIGQECIDELADFAGLKAHVAAITERAMRGEMQFEAALRERVALLKGLPVSVVDEVLAKRITPTPGGRE
LVMTMRANGAYTCLISGGFTLFTEAVAALIGFHENRGNTLLVENGKLSGTAAEPIVGREAKLTTLIELRESSGLDGLDTL
AVGDGANDLGMIQQAGLGVAYHAKPAVAAAAAARIDHGDLTALLYAQGYQRDEFVNA
>Mature_296_residues
SLVATLICNPANPALDSTVLDGARAILGNAGPAQWLWDEVAADIPFESTDSIPAITQRLREARGDLPIDVVVQPQIGRRK
KLFLADMDSTMIGQECIDELADFAGLKAHVAAITERAMRGEMQFEAALRERVALLKGLPVSVVDEVLAKRITPTPGGREL
VMTMRANGAYTCLISGGFTLFTEAVAALIGFHENRGNTLLVENGKLSGTAAEPIVGREAKLTTLIELRESSGLDGLDTLA
VGDGANDLGMIQQAGLGVAYHAKPAVAAAAAARIDHGDLTALLYAQGYQRDEFVNA

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=179, Percent_Identity=33.5195530726257, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1790849, Length=206, Percent_Identity=42.2330097087379, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI115534454, Length=185, Percent_Identity=30.2702702702703, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115534456, Length=185, Percent_Identity=30.2702702702703, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=236, Percent_Identity=36.864406779661, Blast_Score=153, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24661601, Length=196, Percent_Identity=29.5918367346939, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 31432; Mature: 31301

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLVATLICNPANPALDSTVLDGARAILGNAGPAQWLWDEVAADIPFESTDSIPAITQRL
CCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
REARGDLPIDVVVQPQIGRRKKLFLADMDSTMIGQECIDELADFAGLKAHVAAITERAMR
HHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GEMQFEAALRERVALLKGLPVSVVDEVLAKRITPTPGGRELVMTMRANGAYTCLISGGFT
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCHH
LFTEAVAALIGFHENRGNTLLVENGKLSGTAAEPIVGREAKLTTLIELRESSGLDGLDTL
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
AVGDGANDLGMIQQAGLGVAYHAKPAVAAAAAARIDHGDLTALLYAQGYQRDEFVNA
EECCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCC
>Mature Secondary Structure 
SLVATLICNPANPALDSTVLDGARAILGNAGPAQWLWDEVAADIPFESTDSIPAITQRL
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
REARGDLPIDVVVQPQIGRRKKLFLADMDSTMIGQECIDELADFAGLKAHVAAITERAMR
HHHCCCCCEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
GEMQFEAALRERVALLKGLPVSVVDEVLAKRITPTPGGRELVMTMRANGAYTCLISGGFT
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEEECCHH
LFTEAVAALIGFHENRGNTLLVENGKLSGTAAEPIVGREAKLTTLIELRESSGLDGLDTL
HHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEE
AVGDGANDLGMIQQAGLGVAYHAKPAVAAAAAARIDHGDLTALLYAQGYQRDEFVNA
EECCCCCHHHHHHHCCCCEEEECCHHHHHHHHHHCCCCCCEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]