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The map label for this gene is exbB [H]

Identifier: 75676490

GI number: 75676490

Start: 2522735

End: 2523697

Strand: Direct

Name: exbB [H]

Synonym: Nwi_2305

Alternate gene names: 75676490

Gene position: 2522735-2523697 (Clockwise)

Preceding gene: 75676488

Following gene: 75676491

Centisome position: 74.15

GC content: 68.43

Gene sequence:

>963_bases
ATGATGCGTCATTCAGGAATGACATTATCGAGAAAGCGCCATGCGCGGGTTGCGCGCGCTGCGATTGCCGGCGTTGCCCT
GCTCATCGGCGCCTTCGGCCCGCTTCACGCACAAGGACTCCCGCAAGCCACACCGGCCATCACCGCTCCCCATTCGCCCT
CCGGGCCGCCCGCATCGGAGATATCGTCCACCACCGACCACCTCAACGCGACCTCATCGTCGCCCGCACCTGCGTCCGCT
CCGAGCGCCATCATCGCCAACGACTCCGCTTCGCCTCACGAGTTATCTCCGTGGTCGATGTTCATGTCGGCGGATATTGT
CGTTCAGCTGGTGATGATCGGTCTTGCGTTTGCGTCGCTGGTGACGTGGACGATCTGCATCGCGAAGCTGGCGGAGCTGT
CGCTGGCGCGGCGCGCGCTGCGGGCGGCGCTGAACAAGATCGGCGACGCGCGCTCGCTGGCGGAAGCGCAGATGGCGCTC
GGCGCGCGGGAGGGCGTGCTGGCCTCGCTGCTGGCCTCGGCGATGCACGAGGCGCGGCTTTCGGCCGGCATTTCCAGCGA
CGCCGGCATCAAGGAGCGCGCGGCGTCGAGCTTCGCCGAGATCGTCCGCGCGGAATCGCGCCGCATCCGGCTCGGCATGG
GGCTGCTCGCCACCATCGGCGCGACGTCGCCGTTCGTCGGCCTGTTCGGCACCGTGTGGGGCATCATGAACAGCTTCATC
GGGATTTCGAAGTCGCAGACCACCAACCTCGCGGTGGTGGCGCCCGGCATCGCCGAGGCGCTGCTCGCGACCGCGCTCGG
CCTTGTCGCCGCCATTCCGGCGGTCATCATCTACAACTACTTCGCGCGCGTGACGCGGGGCTACACCGAACTGGTCGGGC
GCGCCTCGGGAGCGGCCGGCCGGCTGCTGTCGCGCGATCTGGACCGCACCCACGGCTCTCTTACCTCGCGCGCGGCGGAG
TAG

Upstream 100 bases:

>100_bases
ATGGCCGCGTTCCATGCGCCGGAACGGCCGCGTATATGCGGTGCTGACGCACCGCTCTCAGCAATCAGCGAGCCTGCTCG
CAGAAGAGAGATAAAGTATC

Downstream 100 bases:

>100_bases
GCCGATGGGCGCATCGATCGCGGAAGGCGGCTTCGACGACGACGAGGAGTACGGCGAAGCCCACGAGATCAACGTCACGC
CGTTCATCGACGTGATCCTG

Product: MotA/TolQ/ExbB proton channel

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MMRHSGMTLSRKRHARVARAAIAGVALLIGAFGPLHAQGLPQATPAITAPHSPSGPPASEISSTTDHLNATSSSPAPASA
PSAIIANDSASPHELSPWSMFMSADIVVQLVMIGLAFASLVTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMAL
GAREGVLASLLASAMHEARLSAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFI
GISKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRLLSRDLDRTHGSLTSRAAE

Sequences:

>Translated_320_residues
MMRHSGMTLSRKRHARVARAAIAGVALLIGAFGPLHAQGLPQATPAITAPHSPSGPPASEISSTTDHLNATSSSPAPASA
PSAIIANDSASPHELSPWSMFMSADIVVQLVMIGLAFASLVTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMAL
GAREGVLASLLASAMHEARLSAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFI
GISKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRLLSRDLDRTHGSLTSRAAE
>Mature_320_residues
MMRHSGMTLSRKRHARVARAAIAGVALLIGAFGPLHAQGLPQATPAITAPHSPSGPPASEISSTTDHLNATSSSPAPASA
PSAIIANDSASPHELSPWSMFMSADIVVQLVMIGLAFASLVTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMAL
GAREGVLASLLASAMHEARLSAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFI
GISKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAGRLLSRDLDRTHGSLTSRAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=218, Percent_Identity=53.6697247706422, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1786958, Length=199, Percent_Identity=35.678391959799, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32979; Mature: 32979

Theoretical pI: Translated: 11.11; Mature: 11.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRHSGMTLSRKRHARVARAAIAGVALLIGAFGPLHAQGLPQATPAITAPHSPSGPPASE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
ISSTTDHLNATSSSPAPASAPSAIIANDSASPHELSPWSMFMSADIVVQLVMIGLAFASL
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGAREGVLASLLASAMHEARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFI
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GISKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAG
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RLLSRDLDRTHGSLTSRAAE
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMRHSGMTLSRKRHARVARAAIAGVALLIGAFGPLHAQGLPQATPAITAPHSPSGPPASE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
ISSTTDHLNATSSSPAPASAPSAIIANDSASPHELSPWSMFMSADIVVQLVMIGLAFASL
HHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTWTICIAKLAELSLARRALRAALNKIGDARSLAEAQMALGAREGVLASLLASAMHEARL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAGISSDAGIKERAASSFAEIVRAESRRIRLGMGLLATIGATSPFVGLFGTVWGIMNSFI
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GISKSQTTNLAVVAPGIAEALLATALGLVAAIPAVIIYNYFARVTRGYTELVGRASGAAG
CCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
RLLSRDLDRTHGSLTSRAAE
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]