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The map label for this gene is xlnD [H]

Identifier: 75676367

GI number: 75676367

Start: 2377745

End: 2378983

Strand: Direct

Name: xlnD [H]

Synonym: Nwi_2182

Alternate gene names: 75676367

Gene position: 2377745-2378983 (Clockwise)

Preceding gene: 75676366

Following gene: 75676371

Centisome position: 69.89

GC content: 69.09

Gene sequence:

>1239_bases
ATGCGTGGTGAGGGACAAGGCCGCCTGATCCACCCTGTGCGCACGTTACGCACAGTCGTCATCGCCGGCGCCGGAATCGG
AGGCTTGACGGCGGCGCTGGCGCTGGCGGCGAGAGGGTTTCGCGTCCTCGTCATCGAAACGGCCGAACGCCTCGAAGAGG
CCGGCGCGGGGCTGCAGCTTTCGCCAAATGCAACGCGTATCCTGATTGGGCTCGGCCTGCATGAGCGGCTGTCCGCCCGC
GCGCTAATTCCGGAAGCCGTCAGCATCATGAGCGTAAGGCACGGCGGCGAGATCTGCCGCCTCCCGCTTGGCGAGGCAGC
CGCCTCGCGCGCTGGTGCGCCCTACTGGGTGATGCATCGCGCCGACCTGCAGGCGGCCCTGCTGGAGCAGGTTCACGATC
ATCCCGGCATCGAGCTGCGTCTCGGCGCTAACGCCGAAGACGCGGCCGCATATGCCACCGGCGCGAATGCCGAGGTGTGC
GGCGGCACGACACACCCGCAGGAGACCGCATGGGCGCTGATCGGCGCTGACGGGGTATGGTCCGCCTTGCGCAGGCGGCT
TTTTCCGAACGCTGCGGCGCTGTTTTCCGGCCTGATCGCATGGCGTGGGACCGTCGAGACCGCTCAACTCCCGCATGACA
TGGCCGCGCCGCGCATCCAGCTCTGGATGGGTCCGGACGCGCATCTCGTGACCTATCCGATGTCGGGAGGGCGCCGGATC
AACCTGGTCGCGGTCGTCCCTGGCGGCTGGACTGAGCCCGGCTGGAGCGCGGTCGGAGATGCCGCGGAGATCCAGCGCGC
TTTCGCGCAGGCGTCCTGGCCCCAGCCCGCGCGCTTGATGATCGACGCGGTGGACCACTGGCGCAAATGGGCGCTGTTCA
CGATGCCGCCGATGGCCGCGTGGCACCGCGACACCACAGCCCTGCTCGGCGATGCCGCCCATGCGATGCTGCCGTTCGCC
GCGCAGGGGGCGGGCATGGCGATCGAGGATGCCGCGGTTCTGGCGCGGTGTCTCGGCGAAGCCGCGAACGGGAACTCCGA
AAGCGTCGCGTCCGCGCTCGCGCGTTACGCCGGGCTGCGCCGCGCACGCGTTGCGCGGATGCAAGACACCGCGCAACTAA
ATGGACGAATCTACCATCTTCGGGGCGTCGCCGCCTCGGCGCGCGATCTCGCCATCAGGGCGATGGGTCCGCAGCGTATG
CTGGCGCGTCAGGACTGGATCTACAATTGGCGGCCCTGA

Upstream 100 bases:

>100_bases
TTCTCGATCTCGGCGACGACGGCGAAATCATCTGCCCCTACTGCTCGACGCTGTATCGTTTCGCGGCCGACCTAGGTCCC
GGACAGTCCCGTCCTCCCGG

Downstream 100 bases:

>100_bases
ACCGGGATGGTCCAGGCCCGTCCTTCATCAGGAAGAGCACCTGACGAAGATTACTTGCGAGCGTCGCCTGCGGGCGTCTC
CTGCGCCGCGGAAGCCTCGT

Product: monooxygenase, FAD-binding

Products: NA

Alternate protein names: Constitutive 3-hydroxybenzoate 6-hydroxylase [H]

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MRGEGQGRLIHPVRTLRTVVIAGAGIGGLTAALALAARGFRVLVIETAERLEEAGAGLQLSPNATRILIGLGLHERLSAR
ALIPEAVSIMSVRHGGEICRLPLGEAAASRAGAPYWVMHRADLQAALLEQVHDHPGIELRLGANAEDAAAYATGANAEVC
GGTTHPQETAWALIGADGVWSALRRRLFPNAAALFSGLIAWRGTVETAQLPHDMAAPRIQLWMGPDAHLVTYPMSGGRRI
NLVAVVPGGWTEPGWSAVGDAAEIQRAFAQASWPQPARLMIDAVDHWRKWALFTMPPMAAWHRDTTALLGDAAHAMLPFA
AQGAGMAIEDAAVLARCLGEAANGNSESVASALARYAGLRRARVARMQDTAQLNGRIYHLRGVAASARDLAIRAMGPQRM
LARQDWIYNWRP

Sequences:

>Translated_412_residues
MRGEGQGRLIHPVRTLRTVVIAGAGIGGLTAALALAARGFRVLVIETAERLEEAGAGLQLSPNATRILIGLGLHERLSAR
ALIPEAVSIMSVRHGGEICRLPLGEAAASRAGAPYWVMHRADLQAALLEQVHDHPGIELRLGANAEDAAAYATGANAEVC
GGTTHPQETAWALIGADGVWSALRRRLFPNAAALFSGLIAWRGTVETAQLPHDMAAPRIQLWMGPDAHLVTYPMSGGRRI
NLVAVVPGGWTEPGWSAVGDAAEIQRAFAQASWPQPARLMIDAVDHWRKWALFTMPPMAAWHRDTTALLGDAAHAMLPFA
AQGAGMAIEDAAVLARCLGEAANGNSESVASALARYAGLRRARVARMQDTAQLNGRIYHLRGVAASARDLAIRAMGPQRM
LARQDWIYNWRP
>Mature_412_residues
MRGEGQGRLIHPVRTLRTVVIAGAGIGGLTAALALAARGFRVLVIETAERLEEAGAGLQLSPNATRILIGLGLHERLSAR
ALIPEAVSIMSVRHGGEICRLPLGEAAASRAGAPYWVMHRADLQAALLEQVHDHPGIELRLGANAEDAAAYATGANAEVC
GGTTHPQETAWALIGADGVWSALRRRLFPNAAALFSGLIAWRGTVETAQLPHDMAAPRIQLWMGPDAHLVTYPMSGGRRI
NLVAVVPGGWTEPGWSAVGDAAEIQRAFAQASWPQPARLMIDAVDHWRKWALFTMPPMAAWHRDTTALLGDAAHAMLPFA
AQGAGMAIEDAAVLARCLGEAANGNSESVASALARYAGLRRARVARMQDTAQLNGRIYHLRGVAASARDLAIRAMGPQRM
LARQDWIYNWRP

Specific function: Catalyzes the NAD- or NADP-dependent conversion of 3- hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP. The enzyme shows higher specific activities against the intermediates in the degradation of 2,5- xyleno

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxybenzoate 6-hydroxylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: =1.14.13.24 [H]

Molecular weight: Translated: 44020; Mature: 44020

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEGQGRLIHPVRTLRTVVIAGAGIGGLTAALALAARGFRVLVIETAERLEEAGAGLQL
CCCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEE
SPNATRILIGLGLHERLSARALIPEAVSIMSVRHGGEICRLPLGEAAASRAGAPYWVMHR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCCCEEEEEH
ADLQAALLEQVHDHPGIELRLGANAEDAAAYATGANAEVCGGTTHPQETAWALIGADGVW
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHEECCCCCEECCCCCCCCCCEEEEEECHHHH
SALRRRLFPNAAALFSGLIAWRGTVETAQLPHDMAAPRIQLWMGPDAHLVTYPMSGGRRI
HHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCEE
NLVAVVPGGWTEPGWSAVGDAAEIQRAFAQASWPQPARLMIDAVDHWRKWALFTMPPMAA
EEEEECCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEECCCHHH
WHRDTTALLGDAAHAMLPFAAQGAGMAIEDAAVLARCLGEAANGNSESVASALARYAGLR
HCCCHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RARVARMQDTAQLNGRIYHLRGVAASARDLAIRAMGPQRMLARQDWIYNWRP
HHHHHHHHHHHHHCCEEEEEECCCCCCHHEEEEECCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRGEGQGRLIHPVRTLRTVVIAGAGIGGLTAALALAARGFRVLVIETAERLEEAGAGLQL
CCCCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHCCCEEE
SPNATRILIGLGLHERLSARALIPEAVSIMSVRHGGEICRLPLGEAAASRAGAPYWVMHR
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHCCCCCEEEEEH
ADLQAALLEQVHDHPGIELRLGANAEDAAAYATGANAEVCGGTTHPQETAWALIGADGVW
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHEECCCCCEECCCCCCCCCCEEEEEECHHHH
SALRRRLFPNAAALFSGLIAWRGTVETAQLPHDMAAPRIQLWMGPDAHLVTYPMSGGRRI
HHHHHHHCCCHHHHHHHHHHHCCCCCHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCEE
NLVAVVPGGWTEPGWSAVGDAAEIQRAFAQASWPQPARLMIDAVDHWRKWALFTMPPMAA
EEEEECCCCCCCCCCHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEECCCHHH
WHRDTTALLGDAAHAMLPFAAQGAGMAIEDAAVLARCLGEAANGNSESVASALARYAGLR
HCCCHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
RARVARMQDTAQLNGRIYHLRGVAASARDLAIRAMGPQRMLARQDWIYNWRP
HHHHHHHHHHHHHCCEEEEEECCCCCCHHEEEEECCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12909360 [H]