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The map label for this gene is sugE [H]

Identifier: 75676218

GI number: 75676218

Start: 2219834

End: 2220034

Strand: Direct

Name: sugE [H]

Synonym: Nwi_2028

Alternate gene names: 75676218

Gene position: 2219834-2220034 (Clockwise)

Preceding gene: 75676216

Following gene: 75676224

Centisome position: 65.25

GC content: 55.72

Gene sequence:

>201_bases
ATGTCTTGGGAGGACCGCATGGCCTGGCTTTTATTGTTCGCCGCCGGGGTGATGGAAATCGGCTGGGCGATCGGCCTCAA
ATACACCGACGGGTTTACGCGGCTGGTGCCGTCCATGCTGACATTGGCGGCCATGGCGATCAGCCTTGGTTTGCTCGGAC
TAGAGCATGATGAGTTTAGATTTGGTTGTATCCTGCATTGA

Upstream 100 bases:

>100_bases
GCCGGATGCTTGCCGGACGCTCCCTCTCGCCCCATATCAGGGTCGCGGAAGGACGACCTTTCGTATCCCACACAACCACG
CGCGGGGACGGCCCTGCCTC

Downstream 100 bases:

>100_bases
CGAAGTAGTTGGCGCATTCAGCCGGTGCAACGGTTTCGAGGATCGGAGCGATAGCATTGTAGACGGCCTCGGTGGTCCGC
TGCGCGGCTTTGCGTAGCCA

Product: small multidrug resistance protein SugE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 66; Mature: 65

Protein sequence:

>66_residues
MSWEDRMAWLLLFAAGVMEIGWAIGLKYTDGFTRLVPSMLTLAAMAISLGLLGLEHDEFRFGCILH

Sequences:

>Translated_66_residues
MSWEDRMAWLLLFAAGVMEIGWAIGLKYTDGFTRLVPSMLTLAAMAISLGLLGLEHDEFRFGCILH
>Mature_65_residues
SWEDRMAWLLLFAAGVMEIGWAIGLKYTDGFTRLVPSMLTLAAMAISLGLLGLEHDEFRFGCILH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=57, Percent_Identity=45.6140350877193, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 7388; Mature: 7257

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
7.6 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWEDRMAWLLLFAAGVMEIGWAIGLKYTDGFTRLVPSMLTLAAMAISLGLLGLEHDEFR
CCHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FGCILH
EEEECC
>Mature Secondary Structure 
SWEDRMAWLLLFAAGVMEIGWAIGLKYTDGFTRLVPSMLTLAAMAISLGLLGLEHDEFR
CHHHHHHHHHHHHHHHHHHHHHHCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
FGCILH
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3308458 [H]