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The map label for this gene is queC

Identifier: 75675645

GI number: 75675645

Start: 1584013

End: 1584729

Strand: Direct

Name: queC

Synonym: Nwi_1453

Alternate gene names: 75675645

Gene position: 1584013-1584729 (Clockwise)

Preceding gene: 75675643

Following gene: 75675646

Centisome position: 46.56

GC content: 63.74

Gene sequence:

>717_bases
ATGATCGATGAGCCAGCCTCTCGAACCGCACTGGTGCTGTTTTCCGGAGGCCAGGACTCCGCCACCTGCCTTGCCTGGGC
GCTGCAACGGTTCGCGCGCGTCGAAACGCTGGGGTTCGACTACGGCCAGCGCCATGCAATCGAACTCGACTGCCGCGACA
GTCTGCTCGCGGGCATGGCGTCCCTGCGCCCGGATTGGGCGAAGAAGCTCGGCGAAACCCACACGCTCGCCATTCCGACA
CTGGCGGAGATTTCCGATACGGCGTTGACCCGGAACGTCGCGATCGAAGTAAGCGAGAGCGGATTGCCCAACACCTTCGT
GCCGGGGCGCAATCTGGTGTTCCTGACTTTCGCGGCGGCGCTGGCCTACAGGCGCGGCGTGACGGATATCGTCGGCGGCA
TGTGCGAGACCGATTATTCCGGCTATCCCGATTGCCGTGATGAAACCATCAGAGCCCTGCGCATCGCGCTCAATCTTGGA
ATGGTCAGACAATTCGAACTGCATACGCCGCTGATGCGGCTCGACAAGGGTGCAACCTGGTCGCTTGCGCATGAACTCGG
CGGGACCGGGCTGGTCGATCTCATCCGTGAACATTCCCACACCTGCTATCTCGGCGAGCGCGGTGCGCGGCATGCCTGGG
GTTACGGCTGCGGCGAGTGCCCGGCGTGCGGGTTGCGGGCAAAAGGCTGGCGCGAATATCTGGCGCGGATCGCCTGA

Upstream 100 bases:

>100_bases
ATGCCTGAAGCAGCCCGTCGTCCCAGAAAAAAGCATGGGATCCAGCCTCGCAATCCCCACCGATTGGCGCGGGGAGCCGA
GGGATGCTATTGGCTGCGCC

Downstream 100 bases:

>100_bases
CATGCGGCCGGATCGGACGGAGGCATGAAACCTGACGAATCCAACTGGCCGTCCGCTTGGAAGCCGTCTGATGTGTTATA
GTATTGCAGTCGACTTGATG

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MIDEPASRTALVLFSGGQDSATCLAWALQRFARVETLGFDYGQRHAIELDCRDSLLAGMASLRPDWAKKLGETHTLAIPT
LAEISDTALTRNVAIEVSESGLPNTFVPGRNLVFLTFAAALAYRRGVTDIVGGMCETDYSGYPDCRDETIRALRIALNLG
MVRQFELHTPLMRLDKGATWSLAHELGGTGLVDLIREHSHTCYLGERGARHAWGYGCGECPACGLRAKGWREYLARIA

Sequences:

>Translated_238_residues
MIDEPASRTALVLFSGGQDSATCLAWALQRFARVETLGFDYGQRHAIELDCRDSLLAGMASLRPDWAKKLGETHTLAIPT
LAEISDTALTRNVAIEVSESGLPNTFVPGRNLVFLTFAAALAYRRGVTDIVGGMCETDYSGYPDCRDETIRALRIALNLG
MVRQFELHTPLMRLDKGATWSLAHELGGTGLVDLIREHSHTCYLGERGARHAWGYGCGECPACGLRAKGWREYLARIA
>Mature_238_residues
MIDEPASRTALVLFSGGQDSATCLAWALQRFARVETLGFDYGQRHAIELDCRDSLLAGMASLRPDWAKKLGETHTLAIPT
LAEISDTALTRNVAIEVSESGLPNTFVPGRNLVFLTFAAALAYRRGVTDIVGGMCETDYSGYPDCRDETIRALRIALNLG
MVRQFELHTPLMRLDKGATWSLAHELGGTGLVDLIREHSHTCYLGERGARHAWGYGCGECPACGLRAKGWREYLARIA

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=234, Percent_Identity=45.2991452991453, Blast_Score=192, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_NITWN (Q3SSM7)

Other databases:

- EMBL:   CP000115
- RefSeq:   YP_318066.1
- ProteinModelPortal:   Q3SSM7
- SMR:   Q3SSM7
- STRING:   Q3SSM7
- GeneID:   3675192
- GenomeReviews:   CP000115_GR
- KEGG:   nwi:Nwi_1453
- NMPDR:   fig|323098.3.peg.1528
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- PhylomeDB:   Q3SSM7
- ProtClustDB:   CLSK864419
- BioCyc:   NWIN323098:NWI_1453-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26088; Mature: 26088

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDEPASRTALVLFSGGQDSATCLAWALQRFARVETLGFDYGQRHAIELDCRDSLLAGMA
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
SLRPDWAKKLGETHTLAIPTLAEISDTALTRNVAIEVSESGLPNTFVPGRNLVFLTFAAA
HCCCHHHHHCCCCEEEECCCHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LAYRRGVTDIVGGMCETDYSGYPDCRDETIRALRIALNLGMVRQFELHTPLMRLDKGATW
HHHHCCHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCHHHHHCCCCCC
SLAHELGGTGLVDLIREHSHTCYLGERGARHAWGYGCGECPACGLRAKGWREYLARIA
HHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MIDEPASRTALVLFSGGQDSATCLAWALQRFARVETLGFDYGQRHAIELDCRDSLLAGMA
CCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
SLRPDWAKKLGETHTLAIPTLAEISDTALTRNVAIEVSESGLPNTFVPGRNLVFLTFAAA
HCCCHHHHHCCCCEEEECCCHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LAYRRGVTDIVGGMCETDYSGYPDCRDETIRALRIALNLGMVRQFELHTPLMRLDKGATW
HHHHCCHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHCHHHHHCCCCCC
SLAHELGGTGLVDLIREHSHTCYLGERGARHAWGYGCGECPACGLRAKGWREYLARIA
HHHHHCCCCHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA