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The map label for this gene is 75675602

Identifier: 75675602

GI number: 75675602

Start: 1534194

End: 1535375

Strand: Direct

Name: 75675602

Synonym: Nwi_1410

Alternate gene names: NA

Gene position: 1534194-1535375 (Clockwise)

Preceding gene: 75675601

Following gene: 75675607

Centisome position: 45.1

GC content: 63.62

Gene sequence:

>1182_bases
ATGACATCGTCGCCAGCGGAGTTCGATATCGTTGTCTATGGTGCCAGCGGATTCACCGGCCGGCTGGTCGCCGAATACCT
AGCCGCCAGATATGGTGGCGGCGACCTGAAGTGGGCCATCGCGGGACGCGATCTCGACAAACTGGCGTCGGTGCGCGAGG
CCATCGGCGCGCCCCGTGATCTCCCGCTGGTCGCCGCCGACGCCGGAAACCCGGCGTCGCTCAGGTCCATGGCCGCACGG
ACGGCCTCGGTGCTGAGCACGGTTGGACCTTATCAACTCTACGGCTCCGATCTCATCGCCGTCTGCGCGGCGAGTGGCAC
GGACTATCTTGATCTCTGCGGCGAGCCGATATGGATGCGGCAGATGATCGACGCGCACGAGGCGGAGGCGCGCAGGAGCG
GCGCGCGGATCGTGTTCTCCTGCGGCTACGATTCGCTTCCGTTTGAACTCGGTGTGTTCTTTCTTCAGCAGGCGGCAAAG
GACAGGTTCGGATCGGCCCTCTCTCGGGTCAAGGGCCGCGTGCGCAAGATGAAGGGTACGTTTTCCGGCGGCACCGCCGC
GAGCATGAAGGCGATCTTTTCCGCGGCCGCCAACGATCCCAGTCTGTTGCCCAAACTACGCGATTCCTTCGTGCTGACGC
CGGGGTTTGAAGGGCCGAAACAGCCGCCGGGCAACAAGCCGTTGTTCGATGAAGACCTCGGGATGTGGGTGGCGCCGTTC
GTGATGGCGAACATCAACACCCGCAACGTGCACCGGTCGAATTTCCTGCTCGGTTTCCCTTACGGCCAGGATTTCGTCTA
TGACGAGATGGTGGTCGCGGGGCCGAAGGAGACGGGTGAGGCGACCGCGAAGGCGATCATCGCCGCCAACAACAAGCTCG
GTGCGCAGGGCGGGCCCAAACCAGGCGAGGGACCGTCGAAGGAAGAGCGCGAGAGCGGGCATTACGATCTTCTGTTCCTC
GGCATTGGTTCCGACGGGCGGCAGTTGAAGGCAATCGTAACCGGCGATCGCGATCCCGGCTATGGATCGACTTCGAAGAT
GATCGCGGAATGCGCAATCTGCCTGCGTCACGACACGCCGGACGTCGCCGGCGGTTTCTGGACGCCGGGCGCTGCGATGA
AGGACGCGCTGATCAAGCGGCTCACCAACCACGCCGGGTTGACGTTCACGATCGAGCCGTAA

Upstream 100 bases:

>100_bases
GAACCGGTTCGCGTGAAGAAGTTACGTCAGATCAAAGTGATAGAGTCCGTTTCTCCGTGAAACGGTGAAGGACTCTCAGC
AGGACATTCTCGGGAAGGTC

Downstream 100 bases:

>100_bases
CCAAGCATTGTCCCGGCGCTCGGAAAATTTCCGGAACGGCAGGTCAGATTCTAGCGCGCTGGCTGATCCGGAGCGTGCCG
CAGGTCGGCCCTGTACTGGT

Product: saccharopine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTSSPAEFDIVVYGASGFTGRLVAEYLAARYGGGDLKWAIAGRDLDKLASVREAIGAPRDLPLVAADAGNPASLRSMAAR
TASVLSTVGPYQLYGSDLIAVCAASGTDYLDLCGEPIWMRQMIDAHEAEARRSGARIVFSCGYDSLPFELGVFFLQQAAK
DRFGSALSRVKGRVRKMKGTFSGGTAASMKAIFSAAANDPSLLPKLRDSFVLTPGFEGPKQPPGNKPLFDEDLGMWVAPF
VMANINTRNVHRSNFLLGFPYGQDFVYDEMVVAGPKETGEATAKAIIAANNKLGAQGGPKPGEGPSKEERESGHYDLLFL
GIGSDGRQLKAIVTGDRDPGYGSTSKMIAECAICLRHDTPDVAGGFWTPGAAMKDALIKRLTNHAGLTFTIEP

Sequences:

>Translated_393_residues
MTSSPAEFDIVVYGASGFTGRLVAEYLAARYGGGDLKWAIAGRDLDKLASVREAIGAPRDLPLVAADAGNPASLRSMAAR
TASVLSTVGPYQLYGSDLIAVCAASGTDYLDLCGEPIWMRQMIDAHEAEARRSGARIVFSCGYDSLPFELGVFFLQQAAK
DRFGSALSRVKGRVRKMKGTFSGGTAASMKAIFSAAANDPSLLPKLRDSFVLTPGFEGPKQPPGNKPLFDEDLGMWVAPF
VMANINTRNVHRSNFLLGFPYGQDFVYDEMVVAGPKETGEATAKAIIAANNKLGAQGGPKPGEGPSKEERESGHYDLLFL
GIGSDGRQLKAIVTGDRDPGYGSTSKMIAECAICLRHDTPDVAGGFWTPGAAMKDALIKRLTNHAGLTFTIEP
>Mature_392_residues
TSSPAEFDIVVYGASGFTGRLVAEYLAARYGGGDLKWAIAGRDLDKLASVREAIGAPRDLPLVAADAGNPASLRSMAART
ASVLSTVGPYQLYGSDLIAVCAASGTDYLDLCGEPIWMRQMIDAHEAEARRSGARIVFSCGYDSLPFELGVFFLQQAAKD
RFGSALSRVKGRVRKMKGTFSGGTAASMKAIFSAAANDPSLLPKLRDSFVLTPGFEGPKQPPGNKPLFDEDLGMWVAPFV
MANINTRNVHRSNFLLGFPYGQDFVYDEMVVAGPKETGEATAKAIIAANNKLGAQGGPKPGEGPSKEERESGHYDLLFLG
IGSDGRQLKAIVTGDRDPGYGSTSKMIAECAICLRHDTPDVAGGFWTPGAAMKDALIKRLTNHAGLTFTIEP

Specific function: Unknown

COG id: COG3268

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI55770836, Length=443, Percent_Identity=27.765237020316, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17560066, Length=434, Percent_Identity=26.7281105990783, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI32567112, Length=203, Percent_Identity=35.4679802955665, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71991033, Length=439, Percent_Identity=24.373576309795, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24644140, Length=156, Percent_Identity=38.4615384615385, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24644142, Length=156, Percent_Identity=38.4615384615385, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21356081, Length=156, Percent_Identity=38.4615384615385, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24646278, Length=157, Percent_Identity=38.2165605095541, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: NA

Molecular weight: Translated: 41783; Mature: 41652

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSPAEFDIVVYGASGFTGRLVAEYLAARYGGGDLKWAIAGRDLDKLASVREAIGAPRD
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCC
LPLVAADAGNPASLRSMAARTASVLSTVGPYQLYGSDLIAVCAASGTDYLDLCGEPIWMR
CCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEHHHCCCCCHHHHCCCCHHHH
QMIDAHEAEARRSGARIVFSCGYDSLPFELGVFFLQQAAKDRFGSALSRVKGRVRKMKGT
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSGGTAASMKAIFSAAANDPSLLPKLRDSFVLTPGFEGPKQPPGNKPLFDEDLGMWVAPF
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
VMANINTRNVHRSNFLLGFPYGQDFVYDEMVVAGPKETGEATAKAIIAANNKLGAQGGPK
HHCCCCCCCEECCCEEEECCCCCCCHHCCEEEECCCCCCHHHHEEEEEECCCCCCCCCCC
PGEGPSKEERESGHYDLLFLGIGSDGRQLKAIVTGDRDPGYGSTSKMIAECAICLRHDTP
CCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
DVAGGFWTPGAAMKDALIKRLTNHAGLTFTIEP
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure 
TSSPAEFDIVVYGASGFTGRLVAEYLAARYGGGDLKWAIAGRDLDKLASVREAIGAPRD
CCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCC
LPLVAADAGNPASLRSMAARTASVLSTVGPYQLYGSDLIAVCAASGTDYLDLCGEPIWMR
CCEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCEEEHHHCCCCCHHHHCCCCHHHH
QMIDAHEAEARRSGARIVFSCGYDSLPFELGVFFLQQAAKDRFGSALSRVKGRVRKMKGT
HHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FSGGTAASMKAIFSAAANDPSLLPKLRDSFVLTPGFEGPKQPPGNKPLFDEDLGMWVAPF
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHH
VMANINTRNVHRSNFLLGFPYGQDFVYDEMVVAGPKETGEATAKAIIAANNKLGAQGGPK
HHCCCCCCCEECCCEEEECCCCCCCHHCCEEEECCCCCCHHHHEEEEEECCCCCCCCCCC
PGEGPSKEERESGHYDLLFLGIGSDGRQLKAIVTGDRDPGYGSTSKMIAECAICLRHDTP
CCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
DVAGGFWTPGAAMKDALIKRLTNHAGLTFTIEP
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]