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The map label for this gene is zraS [C]

Identifier: 75675331

GI number: 75675331

Start: 1248011

End: 1250677

Strand: Direct

Name: zraS [C]

Synonym: Nwi_1138

Alternate gene names: 75675331

Gene position: 1248011-1250677 (Clockwise)

Preceding gene: 75675330

Following gene: 75675338

Centisome position: 36.68

GC content: 64.19

Gene sequence:

>2667_bases
ATGGCGGGAAATGAACCCAATGAGGCGCTTGCGCTGCGGGCCCCGATTCAGGCACTCAGGACCCGGCGCAGGCGCATTCC
GCGCCCGCCGCGACAGGCCCCGCCGAATTCCATGACGCCAGATCCCGACATCGATTCACCGCAGGTCGGGCAGGAGCCGG
CGCGGCGGAGCGGCAGCATCCTCCTGGTCCTGCTGGTCGCGGGCGCGATCGTCACGGCCGCCGTGGCGTTCATGGCGCTG
GGGCGTACCGAAGCCCAGCCCTATATTCTGGCGCTGCTGGCCTTGCTGGCGATGGTCGGCCTGTTCACGCTGTTCGCGTT
CGCGGCCGGGATCGTTCGCTTCGCGGACCGCACGGTCGATGATCCGCTGATGCGTCCGATAGCCGATCATGCCTTCGACG
GCATCGCCGTCACCGATTCCGGCGGGCACATCGTTTATGCCAACTCCGCATATCTCACCCTGACCGGAGCTGCGTCGATG
CAGGACGTGCGGCCGGTGGAGCGCGTATTCATCGGCAACCCTGATGTTTCCGAAGCGGTGTTCCGTCTTTTGAAGGCGGC
GCGGGAGGGTAAGCGCCAGCAGGAAGAGGTGCGCGTGGCCGCCGCCGACGGCACCAACGGTCGCTGGCTGCGATTGCGGG
TTCGCCCGCTCGCACAGGCGAAGCGGTACGCCAGATACGCCGTGTGGTCGATCGCCGACATCACCCGCGACCGCGAGCGG
CAAGAAGATGTGTTTCAGGAACTGCGCCATGCGATCGAATATCTCGATCATGCGCCGTGCGGCTTCTTCTCTGTCAACCA
GTCAGGCGATCTCGTCTATGTCAATGCCACGCTTGCCAACTGGCTGGATCACGATCTGGCGGAGATCGGTTCGGGGGGCC
TGAAGCTGACCGACATCGTTTCGGGAGACGGCGCGGCTTTGCTGACGTCGATCATCGCCGCGCCTGGCGAAGTCCGCACC
GAGGTCTTCGATATCGATCTGCGGATGCGCAACGGCAAGACCATGCCGGCGCGCCTGTATCATAAGCTGGCCTTCGGCGC
CGACGGCGTGCCGGGGCCGTCGCGGACGCTGGTGGTCAGCCGCGCCCGCGACGAACGCGTCGATCCGCAGCGGGCGGCTG
AAGTGCGCTTCATGCGCTTCTTCGACCACACGCCGATGGCGATCGCGACGGTCGATAAGTCCGGCGTTGTCGGTCGCGCC
AATGCGCGGTTTGCGAAGCTCGCGCAAAGCCTCAGTCCGGACGGCGCCGTCGCCAGGTCGATTCTCGCCGCTGTCAACGA
GCGCGATCGCGGCCAACTGAGCGCGGCGATTCTCGCCGCGGCGGACGGGCAGGGTGATATTCCGCCGGTCGAAGTGATGT
TGAGTGGCGCGCGCGAGCGGTGGGGGCAGTTCTTCGTCACCGCGGTGGAGGACGATCACGATGCGGAAGCCGCGATCGTC
TACATGCTCGAGACGACCGAGCGGCGCACGCTCGAGAGCCAGATCAATCAATCCCAAAAGATGGAGTCGGTCGGCCAGCT
CGCCGGTGGCATCGCGCATGATTTCAACAATGTTCTGTCCGCCATCATGATGGCGAACGACTTCCTGCTGAACGCGCACA
AGCCGACCGATCCGTCTTTTCAGGACATCATGCAGATCAAGCAGAACGCCAATCGCGCTGCCGCTTTGGTGCGGCAGTTG
CTGGCGTTCTCGCGGCGGCAGACCTTGCAGCCGAAGGTGCTCGATCTCGGCGACACCCTGAGTGACATCGGCATGTTGCT
GAAACGTTTGATCGGCGAAAAGGTCACTTTCCCCGGCGTCGTTCATGGCCGAGACCTGTGGCCGGTCAAGGCCGACGTCT
CGCAGTTCGAGCAGGTGATCGTCAATCTCGTGGTCAATGCGCGCGACGCCATGCCGGACGGCGGCAAGCTCGCGATCCGC
ACCACGAACGTCGCGGCCGCGGAGGTCGCGACGTTCGGCCACAAGGGATTGCCGCCCGCCGACTACGTGCTCGTCGAGAT
CAGCGACACCGGCACCGGCATTCCGCCCGATATCGTCGACAAGATTTTCGAGCCGTTTTTTTCCACCAAGGAGGTAGGCA
AGGGTACCGGGCTCGGCCTGTCCACGGTCTACGGCATCGTGAAGCAGACCGGCGGTTTCATCTACGTCGACTCCAGAACG
GGCGAGGGCACGACGTTCCGTATCTTCCTGCCGCGCCATCACCCCCAGGCCGAGGCGCTGCCGGCGTCGCCCGGCCTTCT
CGGCGAGGCAAAGGAGCCGTCCTCAACAGCCAAGCCGGTGAATACCGATCTGACCGGGCAGGGCACCATCCTGCTGGTGG
AAGACGAGGAGGGGTTGCGCTCGCTCAATGCGCGTGGCCTGCGTTCGCGCGGCTACAGCGTGATCGAGGCTTCCAACGGC
ATCGAAGCACTGGAAGCGCTCGACGAGAAGGACGGTGCTGTCGATCTGGTGGTCTCCGACGTCGTTATGCCCGAAATGGA
CGGGCCGACCCTGCTGCGGAAAATGCGGGTGCGCAATCCCAACCTCAAGATCATTTTTGTGTCGGGTTACGCGGAAGAAG
CGTTCGACAAGAGTCTGCCGGAAAACGAGCAGTTCGCTTTCCTGGCGAAGCCTTTCGCGCTCAGTGCGCTGATTGCCAAG
GTCAAGGAGACGATGACGGCGGCATAA

Upstream 100 bases:

>100_bases
CGAAATCATCGGTTACGTCATGGGGTTGAAGCGCGGCCTTTCGGGACGCCGGGTTTGAGGCCGGCCAGCGGGCAATGGGA
ACAGCATCGGGGCAGCGAAA

Downstream 100 bases:

>100_bases
TTGTTAGGCGGCAGCATTTCCACTCGTCATGGCCGGGCTTTGTCCCGGCCATCCACGTCTTGCTGACGAAAGAAGAACCT
GGATGCCCGGCACAAGGCCT

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 888; Mature: 887

Protein sequence:

>888_residues
MAGNEPNEALALRAPIQALRTRRRRIPRPPRQAPPNSMTPDPDIDSPQVGQEPARRSGSILLVLLVAGAIVTAAVAFMAL
GRTEAQPYILALLALLAMVGLFTLFAFAAGIVRFADRTVDDPLMRPIADHAFDGIAVTDSGGHIVYANSAYLTLTGAASM
QDVRPVERVFIGNPDVSEAVFRLLKAAREGKRQQEEVRVAAADGTNGRWLRLRVRPLAQAKRYARYAVWSIADITRDRER
QEDVFQELRHAIEYLDHAPCGFFSVNQSGDLVYVNATLANWLDHDLAEIGSGGLKLTDIVSGDGAALLTSIIAAPGEVRT
EVFDIDLRMRNGKTMPARLYHKLAFGADGVPGPSRTLVVSRARDERVDPQRAAEVRFMRFFDHTPMAIATVDKSGVVGRA
NARFAKLAQSLSPDGAVARSILAAVNERDRGQLSAAILAAADGQGDIPPVEVMLSGARERWGQFFVTAVEDDHDAEAAIV
YMLETTERRTLESQINQSQKMESVGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNANRAAALVRQL
LAFSRRQTLQPKVLDLGDTLSDIGMLLKRLIGEKVTFPGVVHGRDLWPVKADVSQFEQVIVNLVVNARDAMPDGGKLAIR
TTNVAAAEVATFGHKGLPPADYVLVEISDTGTGIPPDIVDKIFEPFFSTKEVGKGTGLGLSTVYGIVKQTGGFIYVDSRT
GEGTTFRIFLPRHHPQAEALPASPGLLGEAKEPSSTAKPVNTDLTGQGTILLVEDEEGLRSLNARGLRSRGYSVIEASNG
IEALEALDEKDGAVDLVVSDVVMPEMDGPTLLRKMRVRNPNLKIIFVSGYAEEAFDKSLPENEQFAFLAKPFALSALIAK
VKETMTAA

Sequences:

>Translated_888_residues
MAGNEPNEALALRAPIQALRTRRRRIPRPPRQAPPNSMTPDPDIDSPQVGQEPARRSGSILLVLLVAGAIVTAAVAFMAL
GRTEAQPYILALLALLAMVGLFTLFAFAAGIVRFADRTVDDPLMRPIADHAFDGIAVTDSGGHIVYANSAYLTLTGAASM
QDVRPVERVFIGNPDVSEAVFRLLKAAREGKRQQEEVRVAAADGTNGRWLRLRVRPLAQAKRYARYAVWSIADITRDRER
QEDVFQELRHAIEYLDHAPCGFFSVNQSGDLVYVNATLANWLDHDLAEIGSGGLKLTDIVSGDGAALLTSIIAAPGEVRT
EVFDIDLRMRNGKTMPARLYHKLAFGADGVPGPSRTLVVSRARDERVDPQRAAEVRFMRFFDHTPMAIATVDKSGVVGRA
NARFAKLAQSLSPDGAVARSILAAVNERDRGQLSAAILAAADGQGDIPPVEVMLSGARERWGQFFVTAVEDDHDAEAAIV
YMLETTERRTLESQINQSQKMESVGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNANRAAALVRQL
LAFSRRQTLQPKVLDLGDTLSDIGMLLKRLIGEKVTFPGVVHGRDLWPVKADVSQFEQVIVNLVVNARDAMPDGGKLAIR
TTNVAAAEVATFGHKGLPPADYVLVEISDTGTGIPPDIVDKIFEPFFSTKEVGKGTGLGLSTVYGIVKQTGGFIYVDSRT
GEGTTFRIFLPRHHPQAEALPASPGLLGEAKEPSSTAKPVNTDLTGQGTILLVEDEEGLRSLNARGLRSRGYSVIEASNG
IEALEALDEKDGAVDLVVSDVVMPEMDGPTLLRKMRVRNPNLKIIFVSGYAEEAFDKSLPENEQFAFLAKPFALSALIAK
VKETMTAA
>Mature_887_residues
AGNEPNEALALRAPIQALRTRRRRIPRPPRQAPPNSMTPDPDIDSPQVGQEPARRSGSILLVLLVAGAIVTAAVAFMALG
RTEAQPYILALLALLAMVGLFTLFAFAAGIVRFADRTVDDPLMRPIADHAFDGIAVTDSGGHIVYANSAYLTLTGAASMQ
DVRPVERVFIGNPDVSEAVFRLLKAAREGKRQQEEVRVAAADGTNGRWLRLRVRPLAQAKRYARYAVWSIADITRDRERQ
EDVFQELRHAIEYLDHAPCGFFSVNQSGDLVYVNATLANWLDHDLAEIGSGGLKLTDIVSGDGAALLTSIIAAPGEVRTE
VFDIDLRMRNGKTMPARLYHKLAFGADGVPGPSRTLVVSRARDERVDPQRAAEVRFMRFFDHTPMAIATVDKSGVVGRAN
ARFAKLAQSLSPDGAVARSILAAVNERDRGQLSAAILAAADGQGDIPPVEVMLSGARERWGQFFVTAVEDDHDAEAAIVY
MLETTERRTLESQINQSQKMESVGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSFQDIMQIKQNANRAAALVRQLL
AFSRRQTLQPKVLDLGDTLSDIGMLLKRLIGEKVTFPGVVHGRDLWPVKADVSQFEQVIVNLVVNARDAMPDGGKLAIRT
TNVAAAEVATFGHKGLPPADYVLVEISDTGTGIPPDIVDKIFEPFFSTKEVGKGTGLGLSTVYGIVKQTGGFIYVDSRTG
EGTTFRIFLPRHHPQAEALPASPGLLGEAKEPSSTAKPVNTDLTGQGTILLVEDEEGLRSLNARGLRSRGYSVIEASNGI
EALEALDEKDGAVDLVVSDVVMPEMDGPTLLRKMRVRNPNLKIIFVSGYAEEAFDKSLPENEQFAFLAKPFALSALIAKV
KETMTAA

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=28.4584980237154, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788549, Length=308, Percent_Identity=27.2727272727273, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788713, Length=259, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=259, Percent_Identity=31.2741312741313, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI87081816, Length=257, Percent_Identity=27.6264591439689, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=283, Percent_Identity=30.7420494699647, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=122, Percent_Identity=31.1475409836066, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 96223; Mature: 96092

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNEPNEALALRAPIQALRTRRRRIPRPPRQAPPNSMTPDPDIDSPQVGQEPARRSGSI
CCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCE
LLVLLVAGAIVTAAVAFMALGRTEAQPYILALLALLAMVGLFTLFAFAAGIVRFADRTVD
EHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPLMRPIADHAFDGIAVTDSGGHIVYANSAYLTLTGAASMQDVRPVERVFIGNPDVSEAV
CHHHHHHHHHCCCCEEEECCCCEEEEECCEEEEEECCCCHHHCCHHHHHCCCCCCHHHHH
FRLLKAAREGKRQQEEVRVAAADGTNGRWLRLRVRPLAQAKRYARYAVWSIADITRDRER
HHHHHHHHHCCCHHHHEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QEDVFQELRHAIEYLDHAPCGFFSVNQSGDLVYVNATLANWLDHDLAEIGSGGLKLTDIV
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEE
SGDGAALLTSIIAAPGEVRTEVFDIDLRMRNGKTMPARLYHKLAFGADGVPGPSRTLVVS
CCCCHHHHHHHHHCCCHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEE
RARDERVDPQRAAEVRFMRFFDHTPMAIATVDKSGVVGRANARFAKLAQSLSPDGAVARS
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCHHHHHHHHHCCCCHHHHHH
ILAAVNERDRGQLSAAILAAADGQGDIPPVEVMLSGARERWGQFFVTAVEDDHDAEAAIV
HHHHHCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEE
YMLETTERRTLESQINQSQKMESVGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSF
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
QDIMQIKQNANRAAALVRQLLAFSRRQTLQPKVLDLGDTLSDIGMLLKRLIGEKVTFPGV
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCE
VHGRDLWPVKADVSQFEQVIVNLVVNARDAMPDGGKLAIRTTNVAAAEVATFGHKGLPPA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCC
DYVLVEISDTGTGIPPDIVDKIFEPFFSTKEVGKGTGLGLSTVYGIVKQTGGFIYVDSRT
CEEEEEEECCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCC
GEGTTFRIFLPRHHPQAEALPASPGLLGEAKEPSSTAKPVNTDLTGQGTILLVEDEEGLR
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
SLNARGLRSRGYSVIEASNGIEALEALDEKDGAVDLVVSDVVMPEMDGPTLLRKMRVRNP
HHCCCCHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEHHHHCCCCCCHHHHHHHHCCCC
NLKIIFVSGYAEEAFDKSLPENEQFAFLAKPFALSALIAKVKETMTAA
CEEEEEEECCHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGNEPNEALALRAPIQALRTRRRRIPRPPRQAPPNSMTPDPDIDSPQVGQEPARRSGSI
CCCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCE
LLVLLVAGAIVTAAVAFMALGRTEAQPYILALLALLAMVGLFTLFAFAAGIVRFADRTVD
EHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPLMRPIADHAFDGIAVTDSGGHIVYANSAYLTLTGAASMQDVRPVERVFIGNPDVSEAV
CHHHHHHHHHCCCCEEEECCCCEEEEECCEEEEEECCCCHHHCCHHHHHCCCCCCHHHHH
FRLLKAAREGKRQQEEVRVAAADGTNGRWLRLRVRPLAQAKRYARYAVWSIADITRDRER
HHHHHHHHHCCCHHHHEEEEECCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHH
QEDVFQELRHAIEYLDHAPCGFFSVNQSGDLVYVNATLANWLDHDLAEIGSGGLKLTDIV
HHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHHHHHHHHCCCCEEEEEEE
SGDGAALLTSIIAAPGEVRTEVFDIDLRMRNGKTMPARLYHKLAFGADGVPGPSRTLVVS
CCCCHHHHHHHHHCCCHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCEEEEE
RARDERVDPQRAAEVRFMRFFDHTPMAIATVDKSGVVGRANARFAKLAQSLSPDGAVARS
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCHHHHHHHHHCCCCHHHHHH
ILAAVNERDRGQLSAAILAAADGQGDIPPVEVMLSGARERWGQFFVTAVEDDHDAEAAIV
HHHHHCCCCCHHHEEEEEEECCCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEE
YMLETTERRTLESQINQSQKMESVGQLAGGIAHDFNNVLSAIMMANDFLLNAHKPTDPSF
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCH
QDIMQIKQNANRAAALVRQLLAFSRRQTLQPKVLDLGDTLSDIGMLLKRLIGEKVTFPGV
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCE
VHGRDLWPVKADVSQFEQVIVNLVVNARDAMPDGGKLAIRTTNVAAAEVATFGHKGLPPA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCC
DYVLVEISDTGTGIPPDIVDKIFEPFFSTKEVGKGTGLGLSTVYGIVKQTGGFIYVDSRT
CEEEEEEECCCCCCCHHHHHHHHHHHHCHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCC
GEGTTFRIFLPRHHPQAEALPASPGLLGEAKEPSSTAKPVNTDLTGQGTILLVEDEEGLR
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
SLNARGLRSRGYSVIEASNGIEALEALDEKDGAVDLVVSDVVMPEMDGPTLLRKMRVRNP
HHCCCCHHHCCCEEEECCCCHHHHHHHHCCCCCEEEEEHHHHCCCCCCHHHHHHHHCCCC
NLKIIFVSGYAEEAFDKSLPENEQFAFLAKPFALSALIAKVKETMTAA
CEEEEEEECCHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA