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The map label for this gene is xanB [H]

Identifier: 75675268

GI number: 75675268

Start: 1177389

End: 1178801

Strand: Direct

Name: xanB [H]

Synonym: Nwi_1075

Alternate gene names: 75675268

Gene position: 1177389-1178801 (Clockwise)

Preceding gene: 75675267

Following gene: 75675269

Centisome position: 34.61

GC content: 63.91

Gene sequence:

>1413_bases
GTGAGTGAGCGTATCGTCCCGCTCATCATGTGCGGCGGCGCGGGGACCCGGCTGTGGCCAGCCTCGCGGGAGGGGCGTCC
GAAGCAGTTTCTGCCGCTGTTCGGGCCGCGTTCGACGTTTCAGGATACGCTGAGGCGGGTTTCCGACCCCGTGCTGTTCG
AACGGCCGATCGTGGTCACCAACGCCGCCTACCGGTTCATGGTTCTTGAGCAGCTTGCCGAGATCGGGCTCGAAGCGGAC
ATCCTGCTGGAGCCGGCGCGCCGCGATTCTGGGCCGGCGATCGCCGCGGGAGCCGCCTTCGCGCAGATGCGCGACAGCGA
GGCGGTCGTACTCGCGCTTGCGGCGGACCACGTTGTTCGCGACACCCAAGCGTTCGTCTCCGCCTGCCGCCAGGGTCTGG
CTGCCGCCAATGGCGGCCGCATCGTGACCTTCGGCGTCCGGCCGCAGCGTCCGGCGACCGAATACGGTTATATCAACCCT
GGTCCGGCGATTGCGGGTGAGGTGCGGGAGGTGACGACGTTTGTGGAAAAGCCCGATCCACAGACCGCCGCCGGCTACCT
CGATGCGGGGTATCTCTGGAACAGCGGCAACTTCATGTTCCGTGCGGCGGTTCTGCTGGATGAATATCGCAACGTCGATC
CGGACAGCGTCTCTGCTGCGACCGACGCGGTATCCCGTGCCGGCCGGGATCTGGGTTTCGTCATTCTTGATCCGGAGGCT
TTCTCAAGGGCGCGGGCGATTTCGATCGATTACGCCGTCATGGAAAAGACCACTCGCGCCGCCGTGGTGCCGGTCGATTG
CGGCTGGTCGGACGTCGGATCGTGGCATGCGGTTTGGGAGTTGTCGGACAAGGACGGGCAGGGCAATGCGGCGCAGGGGA
TCGCCGTGTTCGAGGATTCCCGCAACTGCAATGTCGCGACCGATAAGGCGCTGGTCGCGCTGGAAGGTGTCGACGATCTC
GTCGTGGTCGCCACGCAGGATGCCGTGCTGGTGTCGCGCCAGAAGGACGCCAACGGGTTGAAACGCCTGGTTACGAAATT
GAAGAGCCTGGCTCCACAGGTCACGGACGAACATCTGCGGGTCCACAGGCCCTGGGGCGCTTACCAGTCGATCGACAGGG
GCGAGCGGCATCAGGTCAAGCGCATCACCGTGAAGGCCGGCGACCGGCTGTCGCTGCAAAAACATCACCATCGCTCGGAG
CACTGGATCGTGGTGCGCGGCACGGCGAGGGTGACGGTCGATGATCTCGTCAAGATCGTGCACGAGAACGAATCGATCTA
TATCCCGATCGGAGCCGTCCACCGGTTGGAGAATCCGGGCAAGATTCCCTTGGAACTGATCGAAGTGCAGACCGGAAGTT
ACCTCGGCGACGACGATATCGTGCGGATCGAGGATGATTATCGGCGAAACTGA

Upstream 100 bases:

>100_bases
AGGGTTCGCCTTTGATCCTGGGTTCGCATGGAAATGGCTGGATTAAGGGTCTGCGAACGTCGGAACCGGGATGGACAAAT
CAGCATGTGGAGATGGTGTT

Downstream 100 bases:

>100_bases
GCTACGGCCCGGGAGCCGAATCGGCTAATCTGTGGATACATTTTCCAGGCTATGTCCGGTCATCCAATCATCGTTCTACC
GGTCAGAGTATCGTGTAATT

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSERIVPLIMCGGAGTRLWPASREGRPKQFLPLFGPRSTFQDTLRRVSDPVLFERPIVVTNAAYRFMVLEQLAEIGLEAD
ILLEPARRDSGPAIAAGAAFAQMRDSEAVVLALAADHVVRDTQAFVSACRQGLAAANGGRIVTFGVRPQRPATEYGYINP
GPAIAGEVREVTTFVEKPDPQTAAGYLDAGYLWNSGNFMFRAAVLLDEYRNVDPDSVSAATDAVSRAGRDLGFVILDPEA
FSRARAISIDYAVMEKTTRAAVVPVDCGWSDVGSWHAVWELSDKDGQGNAAQGIAVFEDSRNCNVATDKALVALEGVDDL
VVVATQDAVLVSRQKDANGLKRLVTKLKSLAPQVTDEHLRVHRPWGAYQSIDRGERHQVKRITVKAGDRLSLQKHHHRSE
HWIVVRGTARVTVDDLVKIVHENESIYIPIGAVHRLENPGKIPLELIEVQTGSYLGDDDIVRIEDDYRRN

Sequences:

>Translated_470_residues
MSERIVPLIMCGGAGTRLWPASREGRPKQFLPLFGPRSTFQDTLRRVSDPVLFERPIVVTNAAYRFMVLEQLAEIGLEAD
ILLEPARRDSGPAIAAGAAFAQMRDSEAVVLALAADHVVRDTQAFVSACRQGLAAANGGRIVTFGVRPQRPATEYGYINP
GPAIAGEVREVTTFVEKPDPQTAAGYLDAGYLWNSGNFMFRAAVLLDEYRNVDPDSVSAATDAVSRAGRDLGFVILDPEA
FSRARAISIDYAVMEKTTRAAVVPVDCGWSDVGSWHAVWELSDKDGQGNAAQGIAVFEDSRNCNVATDKALVALEGVDDL
VVVATQDAVLVSRQKDANGLKRLVTKLKSLAPQVTDEHLRVHRPWGAYQSIDRGERHQVKRITVKAGDRLSLQKHHHRSE
HWIVVRGTARVTVDDLVKIVHENESIYIPIGAVHRLENPGKIPLELIEVQTGSYLGDDDIVRIEDDYRRN
>Mature_469_residues
SERIVPLIMCGGAGTRLWPASREGRPKQFLPLFGPRSTFQDTLRRVSDPVLFERPIVVTNAAYRFMVLEQLAEIGLEADI
LLEPARRDSGPAIAAGAAFAQMRDSEAVVLALAADHVVRDTQAFVSACRQGLAAANGGRIVTFGVRPQRPATEYGYINPG
PAIAGEVREVTTFVEKPDPQTAAGYLDAGYLWNSGNFMFRAAVLLDEYRNVDPDSVSAATDAVSRAGRDLGFVILDPEAF
SRARAISIDYAVMEKTTRAAVVPVDCGWSDVGSWHAVWELSDKDGQGNAAQGIAVFEDSRNCNVATDKALVALEGVDDLV
VVATQDAVLVSRQKDANGLKRLVTKLKSLAPQVTDEHLRVHRPWGAYQSIDRGERHQVKRITVKAGDRLSLQKHHHRSEH
WIVVRGTARVTVDDLVKIVHENESIYIPIGAVHRLENPGKIPLELIEVQTGSYLGDDDIVRIEDDYRRN

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=474, Percent_Identity=48.5232067510549, Blast_Score=428, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51587; Mature: 51456

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERIVPLIMCGGAGTRLWPASREGRPKQFLPLFGPRSTFQDTLRRVSDPVLFERPIVVT
CCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCEEEE
NAAYRFMVLEQLAEIGLEADILLEPARRDSGPAIAAGAAFAQMRDSEAVVLALAADHVVR
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHCCCCEEEEEEEHHHHHH
DTQAFVSACRQGLAAANGGRIVTFGVRPQRPATEYGYINPGPAIAGEVREVTTFVEKPDP
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
QTAAGYLDAGYLWNSGNFMFRAAVLLDEYRNVDPDSVSAATDAVSRAGRDLGFVILDPEA
CCCCCEEECCEEECCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCHH
FSRARAISIDYAVMEKTTRAAVVPVDCGWSDVGSWHAVWELSDKDGQGNAAQGIAVFEDS
HCCCEEEEEEHHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECC
RNCNVATDKALVALEGVDDLVVVATQDAVLVSRQKDANGLKRLVTKLKSLAPQVTDEHLR
CCCCEECCCEEEEECCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEE
VHRPWGAYQSIDRGERHQVKRITVKAGDRLSLQKHHHRSEHWIVVRGTARVTVDDLVKIV
EECCCCCHHCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCCEEEEECCCEEEHHHHHHHH
HENESIYIPIGAVHRLENPGKIPLELIEVQTGSYLGDDDIVRIEDDYRRN
HCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECHHCCCC
>Mature Secondary Structure 
SERIVPLIMCGGAGTRLWPASREGRPKQFLPLFGPRSTFQDTLRRVSDPVLFERPIVVT
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCEEEE
NAAYRFMVLEQLAEIGLEADILLEPARRDSGPAIAAGAAFAQMRDSEAVVLALAADHVVR
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEHHHHHHHHCCCCEEEEEEEHHHHHH
DTQAFVSACRQGLAAANGGRIVTFGVRPQRPATEYGYINPGPAIAGEVREVTTFVEKPDP
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
QTAAGYLDAGYLWNSGNFMFRAAVLLDEYRNVDPDSVSAATDAVSRAGRDLGFVILDPEA
CCCCCEEECCEEECCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCHH
FSRARAISIDYAVMEKTTRAAVVPVDCGWSDVGSWHAVWELSDKDGQGNAAQGIAVFEDS
HCCCEEEEEEHHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEECC
RNCNVATDKALVALEGVDDLVVVATQDAVLVSRQKDANGLKRLVTKLKSLAPQVTDEHLR
CCCCEECCCEEEEECCCCCEEEEEECCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEE
VHRPWGAYQSIDRGERHQVKRITVKAGDRLSLQKHHHRSEHWIVVRGTARVTVDDLVKIV
EECCCCCHHCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCCEEEEECCCEEEHHHHHHHH
HENESIYIPIGAVHRLENPGKIPLELIEVQTGSYLGDDDIVRIEDDYRRN
HCCCEEEEEEHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]