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The map label for this gene is yjiA [H]

Identifier: 75675110

GI number: 75675110

Start: 1004812

End: 1005864

Strand: Direct

Name: yjiA [H]

Synonym: Nwi_0917

Alternate gene names: 75675110

Gene position: 1004812-1005864 (Clockwise)

Preceding gene: 75675109

Following gene: 75675111

Centisome position: 29.54

GC content: 60.49

Gene sequence:

>1053_bases
ATGTCTGATGTAAACGCCTCCGCCTCGACGAAAATCCCCGTAACCGTGCTGACAGGCTATCTCGGCGCCGGCAAGACCAC
GCTTTTGAACCGCATCCTGTCGGAAAATCACGGCAAGAAGTATGCCGTGATCGTCAACGAATTCGGCGAGGTCGGCATCG
ACAACGACCTGATCATCGGCGCCGACGAGGAAGTGTTCGAAATGAACAACGGCTGCGTGTGCTGCACAGTGCGCGGCGAC
CTGGTGCGTATTCTCGAAGGACTGATGAAGCGCAAGGGCAAGTTCGACGCCATCATCGTGGAGACCACGGGCCTAGCCGA
TCCGGCCCCGGTGGCGCAGACGTTCTTCGTCGACGAGGATGTGCAGAACAATGCGCGCCTCGATGCGGTGGTGACGGTGG
CCGACGCCAAGTGGCTGAGCGAGCGGCTGAAGGATGCGCCCGAGGCGAAGAACCAGATCGCCTTCGCCGACGTCATCGTC
CTGAACAAGACCGATCTGGTGTCGCAGCCCGAACTGGCCGAGGTGGAAGCGCGGATTCGCGGCATCAATCCCTACGCGAA
ACTGCACCGCACCGAGCGCTGCCAGGTGGCGCTCTCGGATGTTCTGGAACGCGGCGCGTTCGATCTCGACCGCATCCTCG
AGATCGAGCCGGATTTCCTCGAGAATGACGGCCACGATCATGACCACCACGATCATCACGGTCACGATCATCACGACCAT
GATCATGGCCACGGCCCGAAGCACTATCACGATGAGGAGATGCAGTCGCTGTCGCTGCGTTCGGACAAGCCGCTCGATCA
GGAAAAGTTCATGCCGTGGCTGCAGGAGCTTCTGGCGGCGGAGGGACAGAAGATTCTGCGCTCGAAGGGACTCATGGCGT
TCAGCGGCGATGACGATCGCTACGTGTTTCAGGGCGTTCATATGATGCTGGAGGGCAGCCGCCAGCGTGCATGGAAGCCT
GACGAGAAGCGGGAAAGCCGTCTCGTCTTCATTGGCCGCGAATTGCCGGAAGCCTTGATCCGCGAAGGCTTCCAGAACTG
CATCGCCGCGTGA

Upstream 100 bases:

>100_bases
GGAAGGATCGCGAGGCGGCTCTTGTGGTCGCCGAACGCCGCATGTGCTATTGAATCCTCATTCTCTCCGCGAGGAGAGCA
AAACAGCCCCGAGTTCATTG

Downstream 100 bases:

>100_bases
TGAAAGACACCGCTCCGAAGCAGCACGCCATGGCCTCGATCGGCGAGCGCGTGCGTCCCGTCACCATCGGCTCGCCGGTG
GCAGCTCTTCACTTCATCGG

Product: cobalamin synthesis protein, CobW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSDVNASASTKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEVGIDNDLIIGADEEVFEMNNGCVCCTVRGD
LVRILEGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVQNNARLDAVVTVADAKWLSERLKDAPEAKNQIAFADVIV
LNKTDLVSQPELAEVEARIRGINPYAKLHRTERCQVALSDVLERGAFDLDRILEIEPDFLENDGHDHDHHDHHGHDHHDH
DHGHGPKHYHDEEMQSLSLRSDKPLDQEKFMPWLQELLAAEGQKILRSKGLMAFSGDDDRYVFQGVHMMLEGSRQRAWKP
DEKRESRLVFIGRELPEALIREGFQNCIAA

Sequences:

>Translated_350_residues
MSDVNASASTKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEVGIDNDLIIGADEEVFEMNNGCVCCTVRGD
LVRILEGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVQNNARLDAVVTVADAKWLSERLKDAPEAKNQIAFADVIV
LNKTDLVSQPELAEVEARIRGINPYAKLHRTERCQVALSDVLERGAFDLDRILEIEPDFLENDGHDHDHHDHHGHDHHDH
DHGHGPKHYHDEEMQSLSLRSDKPLDQEKFMPWLQELLAAEGQKILRSKGLMAFSGDDDRYVFQGVHMMLEGSRQRAWKP
DEKRESRLVFIGRELPEALIREGFQNCIAA
>Mature_349_residues
SDVNASASTKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEVGIDNDLIIGADEEVFEMNNGCVCCTVRGDL
VRILEGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDEDVQNNARLDAVVTVADAKWLSERLKDAPEAKNQIAFADVIVL
NKTDLVSQPELAEVEARIRGINPYAKLHRTERCQVALSDVLERGAFDLDRILEIEPDFLENDGHDHDHHDHHGHDHHDHD
HGHGPKHYHDEEMQSLSLRSDKPLDQEKFMPWLQELLAAEGQKILRSKGLMAFSGDDDRYVFQGVHMMLEGSRQRAWKPD
EKRESRLVFIGRELPEALIREGFQNCIAA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=354, Percent_Identity=35.5932203389831, Blast_Score=214, Evalue=9e-56,
Organism=Homo sapiens, GI126722884, Length=354, Percent_Identity=35.3107344632768, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI148727351, Length=354, Percent_Identity=35.3107344632768, Blast_Score=211, Evalue=6e-55,
Organism=Homo sapiens, GI146231952, Length=354, Percent_Identity=35.0282485875706, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI223941779, Length=354, Percent_Identity=33.0508474576271, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI223941776, Length=343, Percent_Identity=33.8192419825073, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI119120938, Length=348, Percent_Identity=30.1724137931034, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI310124599, Length=206, Percent_Identity=26.2135922330097, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI310124603, Length=245, Percent_Identity=24.0816326530612, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87082430, Length=338, Percent_Identity=34.3195266272189, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1788499, Length=162, Percent_Identity=34.5679012345679, Blast_Score=87, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6324356, Length=383, Percent_Identity=29.242819843342, Blast_Score=139, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 39270; Mature: 39139

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVNASASTKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEVGIDNDLIIG
CCCCCCCCCCCCCHHHEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEC
ADEEVFEMNNGCVCCTVRGDLVRILEGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDED
CCHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHEEEECCC
VQNNARLDAVVTVADAKWLSERLKDAPEAKNQIAFADVIVLNKTDLVSQPELAEVEARIR
CCCCCCEEEEEEEHHHHHHHHHHHCCCHHHCCEEEEEEEEECCCCCCCCCCHHHHHHHHC
GINPYAKLHRTERCQVALSDVLERGAFDLDRILEIEPDFLENDGHDHDHHDHHGHDHHDH
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCC
DHGHGPKHYHDEEMQSLSLRSDKPLDQEKFMPWLQELLAAEGQKILRSKGLMAFSGDDDR
CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
YVFQGVHMMLEGSRQRAWKPDEKRESRLVFIGRELPEALIREGFQNCIAA
HHHHHHHHHHCCCHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDVNASASTKIPVTVLTGYLGAGKTTLLNRILSENHGKKYAVIVNEFGEVGIDNDLIIG
CCCCCCCCCCCCHHHEECCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEEEC
ADEEVFEMNNGCVCCTVRGDLVRILEGLMKRKGKFDAIIVETTGLADPAPVAQTFFVDED
CCHHHHCCCCCEEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHEEEECCC
VQNNARLDAVVTVADAKWLSERLKDAPEAKNQIAFADVIVLNKTDLVSQPELAEVEARIR
CCCCCCEEEEEEEHHHHHHHHHHHCCCHHHCCEEEEEEEEECCCCCCCCCCHHHHHHHHC
GINPYAKLHRTERCQVALSDVLERGAFDLDRILEIEPDFLENDGHDHDHHDHHGHDHHDH
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCC
DHGHGPKHYHDEEMQSLSLRSDKPLDQEKFMPWLQELLAAEGQKILRSKGLMAFSGDDDR
CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCH
YVFQGVHMMLEGSRQRAWKPDEKRESRLVFIGRELPEALIREGFQNCIAA
HHHHHHHHHHCCCHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]