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The map label for this gene is murA [H]

Identifier: 75674445

GI number: 75674445

Start: 275304

End: 276593

Strand: Direct

Name: murA [H]

Synonym: Nwi_0246

Alternate gene names: 75674445

Gene position: 275304-276593 (Clockwise)

Preceding gene: 75674444

Following gene: 75674446

Centisome position: 8.09

GC content: 65.5

Gene sequence:

>1290_bases
ATGGATCGCATTCGCATCGTCGGCGGCAACAGGCTCAACGGCACCATTCCGATTTCCGGGGCAAAGAACGCGGCGCTGCC
CTTGATGATCGCCGCGCTCCTGACCGAGGAAACGCTGATTCTCGACAACGTGCCGCGACTTGCGGACGTTGCGCAGTTGC
AGCGCATTCTCGGCAACCACGGCGTCGACATCATGTCGGCGGGCAAGCGTCCGGGTGATCATGAATATCAGGGACAGACC
CTGCATATCTCGGCCGCCAGCGTTATCGACACCACCGCGCCATACGAACTGGTCTCGAAGATGCGGGCCAGCTTCTGGGT
GATCGCGCCGCTTCTGGCGCGGATGCATGAGGCGAGGGTATCGCTGCCCGGCGGCTGCGCCATCGGCACCCGTCCCGTCG
ATCTTCTGATCCTGGCGCTGGAAAAGCTGGGCGCCAGAATCGCGATCGACGGCGGTTATGTGATCGCCAGCGCGCCCGCT
GGCCTGAGGGGCGCCGAGGTGGCGTTTCCCAAGGTGACCGTGAGCGGCACCCATGTCGCGCTGATGGCGGCGACGCTGGC
CAGCGGCACCACCGTCATCACCAACGCGGCCTGCGAGCCGGAGATCGTCGATGTCGCCGATTGTCTCAATAAAATGGGCG
CGCGGGTCTCCGGGGCCGGCACGCCGCGGATCGTCATCGAGGGGGTCGGTAGGCTCGGCGGCGCACGTCATACCGTGCTG
CCCGACCGGATCGAAACCGGCACTTATGCGATGGCGGTGGCGATGACCGGCGGCGAGGTGCTGCTGCGCGGGGCGCGGCC
GGAACTGTTGCAGGCGGCGCTCGACGTGCTGACCGAGGCGGGAGCCGAGATTACGCCGAACAATGAGGGGATTCGCGTCG
CGCGTAACGGCGCCGGCATCAATCCGGTAACGGTCTCCACCGCGCCGTTTCCCGGATTCCCGACCGATCTTCAGGCCCAG
CTCATGGCGTTGATGACGCGCGCCAGGGGAACGTCCCATATCACCGAGACGATTTTCGAGAACCGCTTCATGCACGTGCA
GGAACTGGCGCGGTTAGGCGCGCGCATTCATCTGGACGGCGAAACCGCCACCATCGAAGGCATTGAAACGCTGCGCGGCG
CGCCGGTGATGGCGACGGACCTGCGCGCCTCGGTGTCGCTGGTGATCGCCGGACTCGCCGGTGAGGGGGAGACCATGGTC
AACCGCGTCTACCATCTCGACCGTGGTTTCGAGCAGCTTGAGAAAAAACTGTCGGCGTGCGGCGCCTCGATCGAACGGAT
CAGGGCCTGA

Upstream 100 bases:

>100_bases
CAAGGAACGTGTCAGAACATAGAGATAGAGTCTTTAACCGGTTCCATGGGGCGGTGGCGGGTTCTGGTCCTAAGGACTTC
AACGGAAAACGGGAATCGGC

Downstream 100 bases:

>100_bases
TCCCGACCCGAAGGGCCCGTCAGCGAACAGTGATCTGATTCTCATGGTGCCGGCCGGGTTCGCCGCGCCGGATCGGGGTT
GGTGCGAACCAATGGCGTTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDRIRIVGGNRLNGTIPISGAKNAALPLMIAALLTEETLILDNVPRLADVAQLQRILGNHGVDIMSAGKRPGDHEYQGQT
LHISAASVIDTTAPYELVSKMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLILALEKLGARIAIDGGYVIASAPA
GLRGAEVAFPKVTVSGTHVALMAATLASGTTVITNAACEPEIVDVADCLNKMGARVSGAGTPRIVIEGVGRLGGARHTVL
PDRIETGTYAMAVAMTGGEVLLRGARPELLQAALDVLTEAGAEITPNNEGIRVARNGAGINPVTVSTAPFPGFPTDLQAQ
LMALMTRARGTSHITETIFENRFMHVQELARLGARIHLDGETATIEGIETLRGAPVMATDLRASVSLVIAGLAGEGETMV
NRVYHLDRGFEQLEKKLSACGASIERIRA

Sequences:

>Translated_429_residues
MDRIRIVGGNRLNGTIPISGAKNAALPLMIAALLTEETLILDNVPRLADVAQLQRILGNHGVDIMSAGKRPGDHEYQGQT
LHISAASVIDTTAPYELVSKMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLILALEKLGARIAIDGGYVIASAPA
GLRGAEVAFPKVTVSGTHVALMAATLASGTTVITNAACEPEIVDVADCLNKMGARVSGAGTPRIVIEGVGRLGGARHTVL
PDRIETGTYAMAVAMTGGEVLLRGARPELLQAALDVLTEAGAEITPNNEGIRVARNGAGINPVTVSTAPFPGFPTDLQAQ
LMALMTRARGTSHITETIFENRFMHVQELARLGARIHLDGETATIEGIETLRGAPVMATDLRASVSLVIAGLAGEGETMV
NRVYHLDRGFEQLEKKLSACGASIERIRA
>Mature_429_residues
MDRIRIVGGNRLNGTIPISGAKNAALPLMIAALLTEETLILDNVPRLADVAQLQRILGNHGVDIMSAGKRPGDHEYQGQT
LHISAASVIDTTAPYELVSKMRASFWVIAPLLARMHEARVSLPGGCAIGTRPVDLLILALEKLGARIAIDGGYVIASAPA
GLRGAEVAFPKVTVSGTHVALMAATLASGTTVITNAACEPEIVDVADCLNKMGARVSGAGTPRIVIEGVGRLGGARHTVL
PDRIETGTYAMAVAMTGGEVLLRGARPELLQAALDVLTEAGAEITPNNEGIRVARNGAGINPVTVSTAPFPGFPTDLQAQ
LMALMTRARGTSHITETIFENRFMHVQELARLGARIHLDGETATIEGIETLRGAPVMATDLRASVSLVIAGLAGEGETMV
NRVYHLDRGFEQLEKKLSACGASIERIRA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=428, Percent_Identity=51.1682242990654, Blast_Score=415, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45063; Mature: 45063

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGNRLNGTIPISGAKNAALPLMIAALLTEETLILDNVPRLADVAQLQRILGNH
CCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCC
GVDIMSAGKRPGDHEYQGQTLHISAASVIDTTAPYELVSKMRASFWVIAPLLARMHEARV
CCEEEECCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLPGGCAIGTRPVDLLILALEKLGARIAIDGGYVIASAPAGLRGAEVAFPKVTVSGTHVA
CCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCCEEECCEEEECCCHHH
LMAATLASGTTVITNAACEPEIVDVADCLNKMGARVSGAGTPRIVIEGVGRLGGARHTVL
HHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCEECCCCCCEEEEEECHHCCCCCCCCC
PDRIETGTYAMAVAMTGGEVLLRGARPELLQAALDVLTEAGAEITPNNEGIRVARNGAGI
CCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCC
NPVTVSTAPFPGFPTDLQAQLMALMTRARGTSHITETIFENRFMHVQELARLGARIHLDG
CCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCEEEECC
ETATIEGIETLRGAPVMATDLRASVSLVIAGLAGEGETMVNRVYHLDRGFEQLEKKLSAC
CCEEEHHHHHHCCCCEEEHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHH
GASIERIRA
CCHHHHHCC
>Mature Secondary Structure
MDRIRIVGGNRLNGTIPISGAKNAALPLMIAALLTEETLILDNVPRLADVAQLQRILGNH
CCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCC
GVDIMSAGKRPGDHEYQGQTLHISAASVIDTTAPYELVSKMRASFWVIAPLLARMHEARV
CCEEEECCCCCCCCCCCCCEEEEEHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
SLPGGCAIGTRPVDLLILALEKLGARIAIDGGYVIASAPAGLRGAEVAFPKVTVSGTHVA
CCCCCCCCCCCHHHHHHHHHHHHCCEEEEECCEEEEECCCCCCCCEEECCEEEECCCHHH
LMAATLASGTTVITNAACEPEIVDVADCLNKMGARVSGAGTPRIVIEGVGRLGGARHTVL
HHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCEECCCCCCEEEEEECHHCCCCCCCCC
PDRIETGTYAMAVAMTGGEVLLRGARPELLQAALDVLTEAGAEITPNNEGIRVARNGAGI
CCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCC
NPVTVSTAPFPGFPTDLQAQLMALMTRARGTSHITETIFENRFMHVQELARLGARIHLDG
CCEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCEEEECC
ETATIEGIETLRGAPVMATDLRASVSLVIAGLAGEGETMVNRVYHLDRGFEQLEKKLSAC
CCEEEHHHHHHCCCCEEEHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHH
GASIERIRA
CCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA