Click here to switch to the map view.

The map label for this gene is ydfG [C]

Identifier: 74318803

GI number: 74318803

Start: 2866289

End: 2867053

Strand: Direct

Name: ydfG [C]

Synonym: Tbd_2785

Alternate gene names: 74318803

Gene position: 2866289-2867053 (Clockwise)

Preceding gene: 74318802

Following gene: 74318804

Centisome position: 98.5

GC content: 70.33

Gene sequence:

>765_bases
TTGCCCGCCGCGCCGCTCAAGGTTTTCATCACCGGCGCGAGCTCCGGTCTCGGCGCGGCGCTCGCCCGCCATTACGGCGC
ACGCGGTGCGCAACTCGGCCTCGTCGGCCGCCGCATCGAGGGCTTGCACGCCACGGCTGCGGGCCTCGACGCCCGCGTCT
ACTGCGCCGACGTCCGCGACGCCGCCGCGCTGCAGAAGGCTGCCGCCGCGTTTCTCGAGGCGGTCGGCGCCCCGGACGTC
GTCATCGCCGCGGCCGGCATCAGCGTCGGAACCCTGACCGAGACCGCCGCCGACGCTCCGGTGTTTCGCGCCGTCATGGA
CGCCAACGTGCTCGGCCTCGTGCACACCTTCCAGCCCTTCATCGCATCGATGCAAAAAGGCGGCGTGCTGTGTGGCATTT
CGAGCGTCGCCGGCGTGCGCGGGCTCCCCGGGGGCGGCGCGTATTCGGCTTCGAAGGCCGCGGCGACGGTCTATCTCGAG
GCGCTGCGCCTCGAACTGAAGGCACGCGGCATCGCCGTCGTCACGGTCGCGCCGGGCTATATCGACACGCCGATGACACG
CGTGAACCCCTACGCGATGCCGTTCAGGATGAGCGCCGAAACCGCGGGCGCACGCGTCGCCCGATGCATCGCCCGGCGCC
GCGCCTATGCGGTCATTCCGTGGCAGATGGCGTGGGTCGCTGCGGCGCTCAAATGGCTGCCGAACCCGCTCTATGATTTA
TTATTCGAGAAAGCCCCCCGCAAGCCGCGTGGCTTGCCGACGTGA

Upstream 100 bases:

>100_bases
GGCATGACCGGCAGCGAGGCGCGGCTGTTCGAAGTACTCGACGAACTGATCGCCAAGGCACGGGCCGAGCGGGCCGGTAA
GAAAGCCGCGCCCTAAGCCC

Downstream 100 bases:

>100_bases
CATCCCGCGGGTCGGCCGCGACGTGACCCCCTCCGGAGCAGCGATGACAGCGCCCTTGAACATCATTCTTATCGACGATC
ATCCCTTGCTGCGCATGGGC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 253

Protein sequence:

>254_residues
MPAAPLKVFITGASSGLGAALARHYGARGAQLGLVGRRIEGLHATAAGLDARVYCADVRDAAALQKAAAAFLEAVGAPDV
VIAAAGISVGTLTETAADAPVFRAVMDANVLGLVHTFQPFIASMQKGGVLCGISSVAGVRGLPGGGAYSASKAAATVYLE
ALRLELKARGIAVVTVAPGYIDTPMTRVNPYAMPFRMSAETAGARVARCIARRRAYAVIPWQMAWVAAALKWLPNPLYDL
LFEKAPRKPRGLPT

Sequences:

>Translated_254_residues
MPAAPLKVFITGASSGLGAALARHYGARGAQLGLVGRRIEGLHATAAGLDARVYCADVRDAAALQKAAAAFLEAVGAPDV
VIAAAGISVGTLTETAADAPVFRAVMDANVLGLVHTFQPFIASMQKGGVLCGISSVAGVRGLPGGGAYSASKAAATVYLE
ALRLELKARGIAVVTVAPGYIDTPMTRVNPYAMPFRMSAETAGARVARCIARRRAYAVIPWQMAWVAAALKWLPNPLYDL
LFEKAPRKPRGLPT
>Mature_253_residues
PAAPLKVFITGASSGLGAALARHYGARGAQLGLVGRRIEGLHATAAGLDARVYCADVRDAAALQKAAAAFLEAVGAPDVV
IAAAGISVGTLTETAADAPVFRAVMDANVLGLVHTFQPFIASMQKGGVLCGISSVAGVRGLPGGGAYSASKAAATVYLEA
LRLELKARGIAVVTVAPGYIDTPMTRVNPYAMPFRMSAETAGARVARCIARRRAYAVIPWQMAWVAAALKWLPNPLYDLL
FEKAPRKPRGLPT

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=193, Percent_Identity=35.7512953367876, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI40254992, Length=183, Percent_Identity=30.6010928961749, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI7706318, Length=185, Percent_Identity=30.2702702702703, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31543615, Length=217, Percent_Identity=28.110599078341, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI40807363, Length=244, Percent_Identity=28.2786885245902, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI157739938, Length=187, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI150247226, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI4503817, Length=225, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=28.0898876404494, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082100, Length=185, Percent_Identity=32.4324324324324, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17567345, Length=230, Percent_Identity=29.5652173913043, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508895, Length=245, Percent_Identity=26.530612244898, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71997402, Length=186, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17570069, Length=189, Percent_Identity=33.3333333333333, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564282, Length=244, Percent_Identity=29.0983606557377, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=248, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=248, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=192, Percent_Identity=28.6458333333333, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=192, Percent_Identity=28.6458333333333, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=29.5336787564767, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI21357041, Length=198, Percent_Identity=34.8484848484849, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI23397609, Length=187, Percent_Identity=36.3636363636364, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21358495, Length=255, Percent_Identity=30.5882352941176, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=186, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640442, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=235, Percent_Identity=31.9148936170213, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI116007236, Length=214, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355631, Length=183, Percent_Identity=28.4153005464481, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26295; Mature: 26164

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00061 ADH_SHORT ; PS00664 VINCULIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAPLKVFITGASSGLGAALARHYGARGAQLGLVGRRIEGLHATAAGLDARVYCADVRD
CCCCCEEEEEEECCCCHHHHHHHHHCCCCCEECHHHHHHCCCCHHHCCCCEEEEEECHHH
AAALQKAAAAFLEAVGAPDVVIAAAGISVGTLTETAADAPVFRAVMDANVLGLVHTFQPF
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IASMQKGGVLCGISSVAGVRGLPGGGAYSASKAAATVYLEALRLELKARGIAVVTVAPGY
HHHHHCCCEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
IDTPMTRVNPYAMPFRMSAETAGARVARCIARRRAYAVIPWQMAWVAAALKWLPNPLYDL
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHH
LFEKAPRKPRGLPT
HHHHCCCCCCCCCC
>Mature Secondary Structure 
PAAPLKVFITGASSGLGAALARHYGARGAQLGLVGRRIEGLHATAAGLDARVYCADVRD
CCCCEEEEEEECCCCHHHHHHHHHCCCCCEECHHHHHHCCCCHHHCCCCEEEEEECHHH
AAALQKAAAAFLEAVGAPDVVIAAAGISVGTLTETAADAPVFRAVMDANVLGLVHTFQPF
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
IASMQKGGVLCGISSVAGVRGLPGGGAYSASKAAATVYLEALRLELKARGIAVVTVAPGY
HHHHHCCCEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCC
IDTPMTRVNPYAMPFRMSAETAGARVARCIARRRAYAVIPWQMAWVAAALKWLPNPLYDL
CCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCCHHHHH
LFEKAPRKPRGLPT
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]