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The map label for this gene is argS

Identifier: 74318800

GI number: 74318800

Start: 2863428

End: 2865101

Strand: Direct

Name: argS

Synonym: Tbd_2782

Alternate gene names: 74318800

Gene position: 2863428-2865101 (Clockwise)

Preceding gene: 74318799

Following gene: 74318801

Centisome position: 98.41

GC content: 67.44

Gene sequence:

>1674_bases
ATGTCCAGCACGCATCCCCTCAAAGACCAACTCGCCCTCCTGATCGAAGCCGCGCTCGAAGCGCTGGCGCCGGACGCGCC
GGTCAGTCTCGAGATCGAGCGGCCGAAAAATCCGACGCACGGCGACTTCTCGAGCAACGCGGCGATGCAGCTGGCGCGGC
CGCTGAAAAGAAACCCGCGCGAACTCGCGCAGTTGATCGTCACCGAACTGCCGGCGTCGACGCTCGTCGCCAAGGCCGAC
ATCGCCGGCGCCGGTTTCATCAACTTCCACCTCACGCCGGCCGCCTGGCACGGCATCGTGCGGCAGGTCCGCACCGCCGG
CGCGCAATTCGGGCGCGCGCAACGCGAGACCCCGCAGCGCGTGCTGATCGAGTTCGTGTCGGCCAACCCGACCGGCCCGC
TGCACGTCGGCCACGGCCGCCAGGCGGCGCTTGGCGACGCGCTGTGCAACCTCTACGCCGCGCAGGGCTGGGACGTGTAC
CGCGAGTTCTACTACAACGACGCAGGGGTGCAGATCGCCACGCTCGCGGCGAGCGTGCAGGCCCGCGCGAGGGGCCTGCA
GCCCGGTGACGCGACGTGGCCCGAAGCGGCGTACAACGGCGACTACATCGCAGACATCGCGCGCGACTTCCTCGCCGGCA
AGACTGTGAAATCCGACGATCGCGAATTCACGGCGTCGGGCGACGTCGACGACCTCGATTCGATCCGCCAGTTCGCGGTC
GCCTATCTGCGCCACGAGCAGGATCTCGACCTGCGCGCCTTCGCGGTTCACTTCGACAACTACTATCTCGAATCGAGCCT
CTATACCGACGGACGCGTCGACGCCACGGTGCAGCGCCTCGTCGCCGCCGGCAAGACCTACGAGCAGGACGGCGCGCTGT
GGCTGCGCACGACCGAGTACGGCGACGACAAGGACCGCGTGATGAAGAAGTCCGACGGCACCTACACCTACTTCGTGCCC
GACGTCGCCTACCACATCGCCAAGTGGGAGCGCGGCTTCGCGCGCGCGATCAACATCCAGGGCACCGACCACCACGGCAC
GATCGCGCGCGTGCGTGCCGGCCTGCAGGCCGCGAGCGTCGGCATTCCCGAGGGCTATCCCGACTACCTGCTGCACACGA
TGGTGCGCGTCATGCGCGGCGGCGAAGAGGTCAAGATTTCCAAGCGCGCGGGCAGCTATGTCACGCTGCGCGATCTCATC
GAGTGGACGAGCAAGGACGCGGTGCGCTTCTTCCTGCTCTCGCGCAAGGCCGACACCGAATACGTTTTCGACATCGACCT
CGCGCTCGCGCGCAATAACGACAACCCGGTGTACTACGTGCAGTACGCGCATGCACGCATCTGCCGGGTCTTCGAGGAGT
GGAGCGGCGACGTGGCGACGCTCGCCGACGCCGACCTCGCGCCGCTCGAAGCTGCGCACGAGCTCGCGCTGATGCAGCGC
CTCGCCGAGTATCCCGAAACGGTGGCGAGCGCGGCACGCGACCTCGCGCCACATCTGCTGGTGCACTACCTGCAGATGCT
CGCCGGCGACTTCCACGCCTGGTACAACGCCGAGAAATTCCTCGTCGCCGACGAAGCGACCAAGCGGGCGCGGCTCGCGC
TCGCCGACGCAACGCGCATCGTGATCGTCAACGGCCTCGCCTTGCTCGGCGTGGACGCACCGGAGAAAATGTAA

Upstream 100 bases:

>100_bases
GCGCGCGGTTTTGAGGCCTCGCGGGCGGCCCTTATAATCGCCGGCTTGCCATCCGAACGCCGAATTCGACGAGTTCAGGG
CCCACACGCCGCCCCCCACC

Downstream 100 bases:

>100_bases
GCATGGCAAAACCTGCGAGCCGTTCCGCAAAGCGCGGCGGCAGTTCGATCTTCACCGGCGTGCTGATCGGCTTGATCGTC
GGCGCCGTGCTCGCCGTCGC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MSSTHPLKDQLALLIEAALEALAPDAPVSLEIERPKNPTHGDFSSNAAMQLARPLKRNPRELAQLIVTELPASTLVAKAD
IAGAGFINFHLTPAAWHGIVRQVRTAGAQFGRAQRETPQRVLIEFVSANPTGPLHVGHGRQAALGDALCNLYAAQGWDVY
REFYYNDAGVQIATLAASVQARARGLQPGDATWPEAAYNGDYIADIARDFLAGKTVKSDDREFTASGDVDDLDSIRQFAV
AYLRHEQDLDLRAFAVHFDNYYLESSLYTDGRVDATVQRLVAAGKTYEQDGALWLRTTEYGDDKDRVMKKSDGTYTYFVP
DVAYHIAKWERGFARAINIQGTDHHGTIARVRAGLQAASVGIPEGYPDYLLHTMVRVMRGGEEVKISKRAGSYVTLRDLI
EWTSKDAVRFFLLSRKADTEYVFDIDLALARNNDNPVYYVQYAHARICRVFEEWSGDVATLADADLAPLEAAHELALMQR
LAEYPETVASAARDLAPHLLVHYLQMLAGDFHAWYNAEKFLVADEATKRARLALADATRIVIVNGLALLGVDAPEKM

Sequences:

>Translated_557_residues
MSSTHPLKDQLALLIEAALEALAPDAPVSLEIERPKNPTHGDFSSNAAMQLARPLKRNPRELAQLIVTELPASTLVAKAD
IAGAGFINFHLTPAAWHGIVRQVRTAGAQFGRAQRETPQRVLIEFVSANPTGPLHVGHGRQAALGDALCNLYAAQGWDVY
REFYYNDAGVQIATLAASVQARARGLQPGDATWPEAAYNGDYIADIARDFLAGKTVKSDDREFTASGDVDDLDSIRQFAV
AYLRHEQDLDLRAFAVHFDNYYLESSLYTDGRVDATVQRLVAAGKTYEQDGALWLRTTEYGDDKDRVMKKSDGTYTYFVP
DVAYHIAKWERGFARAINIQGTDHHGTIARVRAGLQAASVGIPEGYPDYLLHTMVRVMRGGEEVKISKRAGSYVTLRDLI
EWTSKDAVRFFLLSRKADTEYVFDIDLALARNNDNPVYYVQYAHARICRVFEEWSGDVATLADADLAPLEAAHELALMQR
LAEYPETVASAARDLAPHLLVHYLQMLAGDFHAWYNAEKFLVADEATKRARLALADATRIVIVNGLALLGVDAPEKM
>Mature_556_residues
SSTHPLKDQLALLIEAALEALAPDAPVSLEIERPKNPTHGDFSSNAAMQLARPLKRNPRELAQLIVTELPASTLVAKADI
AGAGFINFHLTPAAWHGIVRQVRTAGAQFGRAQRETPQRVLIEFVSANPTGPLHVGHGRQAALGDALCNLYAAQGWDVYR
EFYYNDAGVQIATLAASVQARARGLQPGDATWPEAAYNGDYIADIARDFLAGKTVKSDDREFTASGDVDDLDSIRQFAVA
YLRHEQDLDLRAFAVHFDNYYLESSLYTDGRVDATVQRLVAAGKTYEQDGALWLRTTEYGDDKDRVMKKSDGTYTYFVPD
VAYHIAKWERGFARAINIQGTDHHGTIARVRAGLQAASVGIPEGYPDYLLHTMVRVMRGGEEVKISKRAGSYVTLRDLIE
WTSKDAVRFFLLSRKADTEYVFDIDLALARNNDNPVYYVQYAHARICRVFEEWSGDVATLADADLAPLEAAHELALMQRL
AEYPETVASAARDLAPHLLVHYLQMLAGDFHAWYNAEKFLVADEATKRARLALADATRIVIVNGLALLGVDAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI15149476, Length=581, Percent_Identity=23.7521514629948, Blast_Score=107, Evalue=4e-23,
Organism=Escherichia coli, GI1788184, Length=592, Percent_Identity=28.0405405405405, Blast_Score=156, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71985061, Length=614, Percent_Identity=24.7557003257329, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI71985068, Length=568, Percent_Identity=24.4718309859155, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320548, Length=555, Percent_Identity=24.5045045045045, Blast_Score=114, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6321883, Length=545, Percent_Identity=24.0366972477064, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI18859963, Length=599, Percent_Identity=22.0367278797997, Blast_Score=102, Evalue=1e-21,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYR_THIDA (Q3SF80)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316540.1
- ProteinModelPortal:   Q3SF80
- STRING:   Q3SF80
- GeneID:   3672848
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2782
- NMPDR:   fig|292415.3.peg.2400
- eggNOG:   COG0018
- HOGENOM:   HBG695395
- OMA:   FDVYFHE
- PhylomeDB:   Q3SF80
- ProtClustDB:   PRK01611
- BioCyc:   TDEN292415:TBD_2782-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00123
- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080
- Gene3D:   G3DSA:3.30.1360.70
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11956
- PRINTS:   PR01038
- SMART:   SM00836
- TIGRFAMs:   TIGR00456

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d; SSF55190 Arg-tRNA-synth_Ic_N; SSF47323 tRNAsyn_1a_bind

EC number: =6.1.1.19

Molecular weight: Translated: 61607; Mature: 61476

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTHPLKDQLALLIEAALEALAPDAPVSLEIERPKNPTHGDFSSNAAMQLARPLKRNPR
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHH
ELAQLIVTELPASTLVAKADIAGAGFINFHLTPAAWHGIVRQVRTAGAQFGRAQRETPQR
HHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCHHHCCHHH
VLIEFVSANPTGPLHVGHGRQAALGDALCNLYAAQGWDVYREFYYNDAGVQIATLAASVQ
HHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHH
ARARGLQPGDATWPEAAYNGDYIADIARDFLAGKTVKSDDREFTASGDVDDLDSIRQFAV
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCHHHHHHHHHH
AYLRHEQDLDLRAFAVHFDNYYLESSLYTDGRVDATVQRLVAAGKTYEQDGALWLRTTEY
HHHHCCCCCCEEEEEEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCC
GDDKDRVMKKSDGTYTYFVPDVAYHIAKWERGFARAINIQGTDHHGTIARVRAGLQAASV
CCCHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCHHHHHC
GIPEGYPDYLLHTMVRVMRGGEEVKISKRAGSYVTLRDLIEWTSKDAVRFFLLSRKADTE
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCHHHHHHEEECCCCCC
YVFDIDLALARNNDNPVYYVQYAHARICRVFEEWSGDVATLADADLAPLEAAHELALMQR
EEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHH
LAEYPETVASAARDLAPHLLVHYLQMLAGDFHAWYNAEKFLVADEATKRARLALADATRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEECCHHHHHHEEECCCCEE
VIVNGLALLGVDAPEKM
EEEECEEEEECCCCCCC
>Mature Secondary Structure 
SSTHPLKDQLALLIEAALEALAPDAPVSLEIERPKNPTHGDFSSNAAMQLARPLKRNPR
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHH
ELAQLIVTELPASTLVAKADIAGAGFINFHLTPAAWHGIVRQVRTAGAQFGRAQRETPQR
HHHHHHHHHCCHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCHHHCCHHH
VLIEFVSANPTGPLHVGHGRQAALGDALCNLYAAQGWDVYREFYYNDAGVQIATLAASVQ
HHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHH
ARARGLQPGDATWPEAAYNGDYIADIARDFLAGKTVKSDDREFTASGDVDDLDSIRQFAV
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCHHHHHHHHHH
AYLRHEQDLDLRAFAVHFDNYYLESSLYTDGRVDATVQRLVAAGKTYEQDGALWLRTTEY
HHHHCCCCCCEEEEEEEECCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEECCC
GDDKDRVMKKSDGTYTYFVPDVAYHIAKWERGFARAINIQGTDHHGTIARVRAGLQAASV
CCCHHHHHHCCCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCHHHHHC
GIPEGYPDYLLHTMVRVMRGGEEVKISKRAGSYVTLRDLIEWTSKDAVRFFLLSRKADTE
CCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHCCCHHHHHHEEECCCCCC
YVFDIDLALARNNDNPVYYVQYAHARICRVFEEWSGDVATLADADLAPLEAAHELALMQR
EEEEEEEEEEECCCCCEEEEEEHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHH
LAEYPETVASAARDLAPHLLVHYLQMLAGDFHAWYNAEKFLVADEATKRARLALADATRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEECCHHHHHHEEECCCCEE
VIVNGLALLGVDAPEKM
EEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA