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The map label for this gene is regA [H]

Identifier: 74318708

GI number: 74318708

Start: 2770448

End: 2770987

Strand: Direct

Name: regA [H]

Synonym: Tbd_2690

Alternate gene names: 74318708

Gene position: 2770448-2770987 (Clockwise)

Preceding gene: 74318707

Following gene: 74318709

Centisome position: 95.21

GC content: 68.15

Gene sequence:

>540_bases
ATGAACTCTGTGATGCGCTTGTTGATCGTCGAGGACGATGTCGATTTCGCGACGGCCCTCGCACGGGCGATGAAGAAACG
CGGCTTCGAGGTCGCGCTCGCCCACGACGCCGTCGAGGCCGCCCGCATCGCCGCGCAATTCGTGCCGAGCCACGCCGTGG
TCGACCTCAAGTTGCCGGGCAAGTCGGGACTCGATGTCGTCGCTACGCTGGCCGCGCGCGTGCCGGCGCCGGCGATCGTC
GTGCTGACAGGCTACGCGAGCATCGCGACCGCGGTCGCCGCCGTGCGCCTCGGCGCGCGTCACTACCTCGCCAAGCCTGC
TGACGCCGACGAGATCGTCGCCGCGCTGCTGCGCGACGAGCCCGACACGACGGTCGATGTCAGCCCGCAGCCGCTGTCCG
TCGCACGGCTCGAATGGGAACATATCCAGAAGGTGCTGAACGAGCACGACGGCAACATCTCGGCGACCGCGCGCGCGCTG
AAAATGCACCGCCGGACGCTGCAGCGAAAGCTCGAAAAGAACCCGCCCCGAACGGGCTGA

Upstream 100 bases:

>100_bases
CCCATGCCACGCTCGAACGGCTCGGCGGCAGCCTCACGCTGACCGAACGCAAGGGCGGCGGCTCGCGCGTGAGTATCCGT
CTACCCTGGAGACCGCTCCC

Downstream 100 bases:

>100_bases
GGACCCGGCGCACGTCGCGTCATCCTGCTGACAGATTCCGGGAATACGGTGGCAGCGTCGGCCCCGCCGACCCCTTCCCG
CCCATCTTCACAGGAGCCCG

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNSVMRLLIVEDDVDFATALARAMKKRGFEVALAHDAVEAARIAAQFVPSHAVVDLKLPGKSGLDVVATLAARVPAPAIV
VLTGYASIATAVAAVRLGARHYLAKPADADEIVAALLRDEPDTTVDVSPQPLSVARLEWEHIQKVLNEHDGNISATARAL
KMHRRTLQRKLEKNPPRTG

Sequences:

>Translated_179_residues
MNSVMRLLIVEDDVDFATALARAMKKRGFEVALAHDAVEAARIAAQFVPSHAVVDLKLPGKSGLDVVATLAARVPAPAIV
VLTGYASIATAVAAVRLGARHYLAKPADADEIVAALLRDEPDTTVDVSPQPLSVARLEWEHIQKVLNEHDGNISATARAL
KMHRRTLQRKLEKNPPRTG
>Mature_179_residues
MNSVMRLLIVEDDVDFATALARAMKKRGFEVALAHDAVEAARIAAQFVPSHAVVDLKLPGKSGLDVVATLAARVPAPAIV
VLTGYASIATAVAAVRLGARHYLAKPADADEIVAALLRDEPDTTVDVSPQPLSVARLEWEHIQKVLNEHDGNISATARAL
KMHRRTLQRKLEKNPPRTG

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=112, Percent_Identity=30.3571428571429, Blast_Score=68, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=31.8181818181818, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR002197
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19262; Mature: 19262

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVMRLLIVEDDVDFATALARAMKKRGFEVALAHDAVEAARIAAQFVPSHAVVDLKLPG
CCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCC
KSGLDVVATLAARVPAPAIVVLTGYASIATAVAAVRLGARHYLAKPADADEIVAALLRDE
CCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PDTTVDVSPQPLSVARLEWEHIQKVLNEHDGNISATARALKMHRRTLQRKLEKNPPRTG
CCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNSVMRLLIVEDDVDFATALARAMKKRGFEVALAHDAVEAARIAAQFVPSHAVVDLKLPG
CCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCEEEEEECCC
KSGLDVVATLAARVPAPAIVVLTGYASIATAVAAVRLGARHYLAKPADADEIVAALLRDE
CCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
PDTTVDVSPQPLSVARLEWEHIQKVLNEHDGNISATARALKMHRRTLQRKLEKNPPRTG
CCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA