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The map label for this gene is regB [H]

Identifier: 74318707

GI number: 74318707

Start: 2769192

End: 2770451

Strand: Direct

Name: regB [H]

Synonym: Tbd_2689

Alternate gene names: 74318707

Gene position: 2769192-2770451 (Clockwise)

Preceding gene: 74318703

Following gene: 74318708

Centisome position: 95.17

GC content: 69.92

Gene sequence:

>1260_bases
ATGACGTCTGCGGACGATTCGACCCTGCTCTCCACGCTGCCGGCGCGTGCCCTGCTCGGGCGCCTGCTCGTCATGCGGGT
CGCGCTGCTCGCGGGCGCCGGGGCAGGAATCGGCTGGCTGCACTGGGGCCTCGGCATCCGCATGCCGCTTGCACCCATGG
CCGCGGTGCTCGTGCTGATGGCGCTGTTCGCGCTGACCACAGCGTGGCGGCTGCGCCAGGACGTGCCCGCCACGCAGATC
GAATTTCTTGCGCATCTGCTCGTCGACCTGACCGCGTTCGCCGTGCTCGTGTACTTCAGCGGCGGCGCGACCAACCCCTT
CGTATCGCTGATGCTGGTTCCGGTCGTGATCGCTGCGATCAGCCTGCGCGCGCCCTGGGTGTGGCTGCTTGCAGCGGTTG
CAGGCGGCTATTACGCGCTGCTGCTGTTCGCTTACCAGCCGCTCGCCGTGTCCGACCCGGTGGCCGCGTACGGCATGCAC
CTCGGCGGCATGTGGTTCAACTTCCTCATCAGCGCGGGGCTGATAGCGAGCTTCGTCACGCGCATGCACGGCGCCTTGCG
CAGGCGCGACCAGGAACTCGCATCGCTGCGCGAGAAGCAACTGCGCGACGAACGCATCGTCGCACTCGGCACGCAGGCGG
CACTCGCCGCGCACGAACTCGCCACCCCGCTCGCGACGATCCAGACGACAGCGCACGAGCTCGCTTCGGAGTTCGCGAAC
GATCCCGAGATCGGCGCCGACTGCCGATTGCTCGAACGCCAGGCGCGCGCGTGCAAGGACATTCTGACCCGGCTCGCGGC
GCGCGCGAATGACGGCACTACGCCCCCGGCGCAGCCGCTGGCCGAATGGCTGGCCGGGCTCGTCGAACGTTGGCAGATGC
TGCGCCCCGACGCCGAGGTGGCGACGACTTTGCCCACGTCCGCGGCGGCTTTCGTGCCGCCCGACGGACTCGAGCAGGCC
GTCATGAACGTGCTGAACAACGCCGCGGACGCCGCGCCGGCAGCGGTCGAGTTCCGCGCTTCCGTCGACGCCGACGCGCT
CGTCATCGAAGTCGGCGACCGCGGTCCCGGCTTCACGCCCGAACAGAAGGCCCAAGCCGGCCGCGTGCTGTTCAGCGGCA
AGGCGGGACGCGGCTGGGGCGTCGGCCTCGCACTGACCCATGCCACGCTCGAACGGCTCGGCGGCAGCCTCACGCTGACC
GAACGCAAGGGCGGCGGCTCGCGCGTGAGTATCCGTCTACCCTGGAGACCGCTCCCATGA

Upstream 100 bases:

>100_bases
AGTCAGAACTGCCCGATCACTCTAGGGCAGGCGCGGACGCCGCGCAATTGGACAAATTGTCGCAGCGGAGCACGCCGTCG
AAGACGCATACAATTCGGCC

Downstream 100 bases:

>100_bases
ACTCTGTGATGCGCTTGTTGATCGTCGAGGACGATGTCGATTTCGCGACGGCCCTCGCACGGGCGATGAAGAAACGCGGC
TTCGAGGTCGCGCTCGCCCA

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MTSADDSTLLSTLPARALLGRLLVMRVALLAGAGAGIGWLHWGLGIRMPLAPMAAVLVLMALFALTTAWRLRQDVPATQI
EFLAHLLVDLTAFAVLVYFSGGATNPFVSLMLVPVVIAAISLRAPWVWLLAAVAGGYYALLLFAYQPLAVSDPVAAYGMH
LGGMWFNFLISAGLIASFVTRMHGALRRRDQELASLREKQLRDERIVALGTQAALAAHELATPLATIQTTAHELASEFAN
DPEIGADCRLLERQARACKDILTRLAARANDGTTPPAQPLAEWLAGLVERWQMLRPDAEVATTLPTSAAAFVPPDGLEQA
VMNVLNNAADAAPAAVEFRASVDADALVIEVGDRGPGFTPEQKAQAGRVLFSGKAGRGWGVGLALTHATLERLGGSLTLT
ERKGGGSRVSIRLPWRPLP

Sequences:

>Translated_419_residues
MTSADDSTLLSTLPARALLGRLLVMRVALLAGAGAGIGWLHWGLGIRMPLAPMAAVLVLMALFALTTAWRLRQDVPATQI
EFLAHLLVDLTAFAVLVYFSGGATNPFVSLMLVPVVIAAISLRAPWVWLLAAVAGGYYALLLFAYQPLAVSDPVAAYGMH
LGGMWFNFLISAGLIASFVTRMHGALRRRDQELASLREKQLRDERIVALGTQAALAAHELATPLATIQTTAHELASEFAN
DPEIGADCRLLERQARACKDILTRLAARANDGTTPPAQPLAEWLAGLVERWQMLRPDAEVATTLPTSAAAFVPPDGLEQA
VMNVLNNAADAAPAAVEFRASVDADALVIEVGDRGPGFTPEQKAQAGRVLFSGKAGRGWGVGLALTHATLERLGGSLTLT
ERKGGGSRVSIRLPWRPLP
>Mature_418_residues
TSADDSTLLSTLPARALLGRLLVMRVALLAGAGAGIGWLHWGLGIRMPLAPMAAVLVLMALFALTTAWRLRQDVPATQIE
FLAHLLVDLTAFAVLVYFSGGATNPFVSLMLVPVVIAAISLRAPWVWLLAAVAGGYYALLLFAYQPLAVSDPVAAYGMHL
GGMWFNFLISAGLIASFVTRMHGALRRRDQELASLREKQLRDERIVALGTQAALAAHELATPLATIQTTAHELASEFAND
PEIGADCRLLERQARACKDILTRLAARANDGTTPPAQPLAEWLAGLVERWQMLRPDAEVATTLPTSAAAFVPPDGLEQAV
MNVLNNAADAAPAAVEFRASVDADALVIEVGDRGPGFTPEQKAQAGRVLFSGKAGRGWGVGLALTHATLERLGGSLTLTE
RKGGGSRVSIRLPWRPLP

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44578; Mature: 44447

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSADDSTLLSTLPARALLGRLLVMRVALLAGAGAGIGWLHWGLGIRMPLAPMAAVLVLM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
ALFALTTAWRLRQDVPATQIEFLAHLLVDLTAFAVLVYFSGGATNPFVSLMLVPVVIAAI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SLRAPWVWLLAAVAGGYYALLLFAYQPLAVSDPVAAYGMHLGGMWFNFLISAGLIASFVT
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMHGALRRRDQELASLREKQLRDERIVALGTQAALAAHELATPLATIQTTAHELASEFAN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPEIGADCRLLERQARACKDILTRLAARANDGTTPPAQPLAEWLAGLVERWQMLRPDAEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
ATTLPTSAAAFVPPDGLEQAVMNVLNNAADAAPAAVEFRASVDADALVIEVGDRGPGFTP
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCCCEEEEEECCCCCCCCC
EQKAQAGRVLFSGKAGRGWGVGLALTHATLERLGGSLTLTERKGGGSRVSIRLPWRPLP
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure 
TSADDSTLLSTLPARALLGRLLVMRVALLAGAGAGIGWLHWGLGIRMPLAPMAAVLVLM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCHHHHHHHHHHH
ALFALTTAWRLRQDVPATQIEFLAHLLVDLTAFAVLVYFSGGATNPFVSLMLVPVVIAAI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SLRAPWVWLLAAVAGGYYALLLFAYQPLAVSDPVAAYGMHLGGMWFNFLISAGLIASFVT
HHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMHGALRRRDQELASLREKQLRDERIVALGTQAALAAHELATPLATIQTTAHELASEFAN
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DPEIGADCRLLERQARACKDILTRLAARANDGTTPPAQPLAEWLAGLVERWQMLRPDAEV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHH
ATTLPTSAAAFVPPDGLEQAVMNVLNNAADAAPAAVEFRASVDADALVIEVGDRGPGFTP
HHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCCCEEEEEECCCCCCCCC
EQKAQAGRVLFSGKAGRGWGVGLALTHATLERLGGSLTLTERKGGGSRVSIRLPWRPLP
HHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]