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The map label for this gene is intA [H]

Identifier: 74318693

GI number: 74318693

Start: 2750091

End: 2751422

Strand: Direct

Name: intA [H]

Synonym: Tbd_2675

Alternate gene names: 74318693

Gene position: 2750091-2751422 (Clockwise)

Preceding gene: 74318689

Following gene: 74318694

Centisome position: 94.51

GC content: 59.01

Gene sequence:

>1332_bases
ATGGGAAGACTTGCCGCCGTGACATGCGACACCGTGAAGCCCGACCCGAAGCGTGACCGCTTGCTCGGCGATGGTGACGG
TCTGTTTTTGCGGATTCGACCGCACGGTACGAAAACATGGGTAATTGAGTATGAGTTTCAGGGCCGTCGCACCAAATACA
CCATCGGTAGTTACTCGCGCAACGGCGCTCCAGGCGAGAGTATTCCAGACTGGCTGGGGCACGGCCAGCAGTCCCTTACC
CAGGCCCGGTCAATAGCCGGAAGTTGGAAAGCGGCGCGCAGAGGTGGCCACGACCCGGCGGCAGAGTGGGAAGCGCTGCA
GGCCAAAGAAAAGCAAGCCGCGGCCGAACTGCAGGCGGCCCAGAAAGCCGAGCAACAGCAACCTACGGTCACGAACGCCA
TAGATTCCTTCATGCAGAAGATTATGGCCGGCAAAAAGAGCGCACCGGCGATCCGCTATCGCCTTGACCGGCTGGCTGCC
CTGCTCGGCGACAAGAAAATTCGGGATGTGACCCGGCAGGACGTGATCGCTGCCCTCGACACTATCGCCGAGGGGCTGCG
GGAGGGGCAGACGGCCAAACAACTGGCAGGTGAGGTGTTGACCCAAGCCAAACGCGTCTGGCGTTTCGCAAGAGCGCGGG
AATGGGTGTTGGTTTCCTGTGTGGAAGAACTAACCCGGCGGGACTTCGACGCCAAACCCCGTAAGCGCGATGTGACACTG
CGGTTCGACGAACTGGTCGTGGTCTGGCGAACGCTCGATGATCCCAGGAAATGCAAGGCCGACCCGGTGACGGTTGCGGC
AATGAAATTGCTGATTTTGACCGGACAGCGGGAGAGCGAAGTTTGCGAGGCCCCCTGGAAGGAGTTCGACCTAGCCCAAG
GGCTGTGGCGCATCCCCCCGGACCGCACCAAGGCGGGTCGCGCCCATCTCGTTCACCTCGCCCCCCAGGCGGTCAAGATC
CTTGAAGATGTAAAGAAGATCACAGGAAAGGAACGCTTTGTTTTCGCTTCCCCCTTGAGGGACAAACAACCGGTCTATGG
GCGATCCGTCAACAACGCCCTGAAGTCCCTATTTAGGAGAGGTATGTTGTCGAACGTAACTCCCTGCACCATCCATGATT
TCCGCAGGACGCTGGTAACCCGCCTCCCCGATCTCGGATTCGAACATTTTTTGGGTCACAAGATTGCCAACCATATGTTG
TCAGGCGTGTCCGCCCACTACAACCACAACGCCTATGAAACAGATCGGGAGGCGGCACTGAAGGCATGGGCCGCACGCCT
CGAAGTGCTGGCAACGGAAAACAACGTAACCCAATTGCATCAAGCAGCATGA

Upstream 100 bases:

>100_bases
ATTACTGGCAACCCAAGCGGGCGTTGTGCTTGTTTGTTCCTGGTAGCGCCTATAGAATCCCACCCAAATCCCCACCCACA
TTCCCACCCTAGGAGCAGCC

Downstream 100 bases:

>100_bases
TCGTTTTCGCCGCGCCTAGCCCGACAGGGCGAATACTGGGAACCCTTGCCCGACTGGCGCGGCAACCAACTCAAGGGGCG
TGTAAGGGACGCCATGTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MGRLAAVTCDTVKPDPKRDRLLGDGDGLFLRIRPHGTKTWVIEYEFQGRRTKYTIGSYSRNGAPGESIPDWLGHGQQSLT
QARSIAGSWKAARRGGHDPAAEWEALQAKEKQAAAELQAAQKAEQQQPTVTNAIDSFMQKIMAGKKSAPAIRYRLDRLAA
LLGDKKIRDVTRQDVIAALDTIAEGLREGQTAKQLAGEVLTQAKRVWRFARAREWVLVSCVEELTRRDFDAKPRKRDVTL
RFDELVVVWRTLDDPRKCKADPVTVAAMKLLILTGQRESEVCEAPWKEFDLAQGLWRIPPDRTKAGRAHLVHLAPQAVKI
LEDVKKITGKERFVFASPLRDKQPVYGRSVNNALKSLFRRGMLSNVTPCTIHDFRRTLVTRLPDLGFEHFLGHKIANHML
SGVSAHYNHNAYETDREAALKAWAARLEVLATENNVTQLHQAA

Sequences:

>Translated_443_residues
MGRLAAVTCDTVKPDPKRDRLLGDGDGLFLRIRPHGTKTWVIEYEFQGRRTKYTIGSYSRNGAPGESIPDWLGHGQQSLT
QARSIAGSWKAARRGGHDPAAEWEALQAKEKQAAAELQAAQKAEQQQPTVTNAIDSFMQKIMAGKKSAPAIRYRLDRLAA
LLGDKKIRDVTRQDVIAALDTIAEGLREGQTAKQLAGEVLTQAKRVWRFARAREWVLVSCVEELTRRDFDAKPRKRDVTL
RFDELVVVWRTLDDPRKCKADPVTVAAMKLLILTGQRESEVCEAPWKEFDLAQGLWRIPPDRTKAGRAHLVHLAPQAVKI
LEDVKKITGKERFVFASPLRDKQPVYGRSVNNALKSLFRRGMLSNVTPCTIHDFRRTLVTRLPDLGFEHFLGHKIANHML
SGVSAHYNHNAYETDREAALKAWAARLEVLATENNVTQLHQAA
>Mature_442_residues
GRLAAVTCDTVKPDPKRDRLLGDGDGLFLRIRPHGTKTWVIEYEFQGRRTKYTIGSYSRNGAPGESIPDWLGHGQQSLTQ
ARSIAGSWKAARRGGHDPAAEWEALQAKEKQAAAELQAAQKAEQQQPTVTNAIDSFMQKIMAGKKSAPAIRYRLDRLAAL
LGDKKIRDVTRQDVIAALDTIAEGLREGQTAKQLAGEVLTQAKRVWRFARAREWVLVSCVEELTRRDFDAKPRKRDVTLR
FDELVVVWRTLDDPRKCKADPVTVAAMKLLILTGQRESEVCEAPWKEFDLAQGLWRIPPDRTKAGRAHLVHLAPQAVKIL
EDVKKITGKERFVFASPLRDKQPVYGRSVNNALKSLFRRGMLSNVTPCTIHDFRRTLVTRLPDLGFEHFLGHKIANHMLS
GVSAHYNHNAYETDREAALKAWAARLEVLATENNVTQLHQAA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=425, Percent_Identity=26.5882352941176, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI145693166, Length=441, Percent_Identity=26.7573696145125, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 49783; Mature: 49651

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRLAAVTCDTVKPDPKRDRLLGDGDGLFLRIRPHGTKTWVIEYEFQGRRTKYTIGSYSR
CCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCEEEEEECCCCC
NGAPGESIPDWLGHGQQSLTQARSIAGSWKAARRGGHDPAAEWEALQAKEKQAAAELQAA
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKAEQQQPTVTNAIDSFMQKIMAGKKSAPAIRYRLDRLAALLGDKKIRDVTRQDVIAALD
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TIAEGLREGQTAKQLAGEVLTQAKRVWRFARAREWVLVSCVEELTRRDFDAKPRKRDVTL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
RFDELVVVWRTLDDPRKCKADPVTVAAMKLLILTGQRESEVCEAPWKEFDLAQGLWRIPP
EHHHHEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCC
DRTKAGRAHLVHLAPQAVKILEDVKKITGKERFVFASPLRDKQPVYGRSVNNALKSLFRR
CCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
GMLSNVTPCTIHDFRRTLVTRLPDLGFEHFLGHKIANHMLSGVSAHYNHNAYETDREAAL
HHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
KAWAARLEVLATENNVTQLHQAA
HHHHHHHHHHCCCCCHHHHHHCC
>Mature Secondary Structure 
GRLAAVTCDTVKPDPKRDRLLGDGDGLFLRIRPHGTKTWVIEYEFQGRRTKYTIGSYSR
CCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCEEEEEEEEECCCEEEEEECCCCC
NGAPGESIPDWLGHGQQSLTQARSIAGSWKAARRGGHDPAAEWEALQAKEKQAAAELQAA
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKAEQQQPTVTNAIDSFMQKIMAGKKSAPAIRYRLDRLAALLGDKKIRDVTRQDVIAALD
HHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
TIAEGLREGQTAKQLAGEVLTQAKRVWRFARAREWVLVSCVEELTRRDFDAKPRKRDVTL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
RFDELVVVWRTLDDPRKCKADPVTVAAMKLLILTGQRESEVCEAPWKEFDLAQGLWRIPP
EHHHHEEEECCCCCHHHCCCCCHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHCCCCCCCC
DRTKAGRAHLVHLAPQAVKILEDVKKITGKERFVFASPLRDKQPVYGRSVNNALKSLFRR
CCCCCCCCEEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHH
GMLSNVTPCTIHDFRRTLVTRLPDLGFEHFLGHKIANHMLSGVSAHYNHNAYETDREAAL
HHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
KAWAARLEVLATENNVTQLHQAA
HHHHHHHHHHCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]