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The map label for this gene is ybaL [H]

Identifier: 74318487

GI number: 74318487

Start: 2544158

End: 2545867

Strand: Direct

Name: ybaL [H]

Synonym: Tbd_2469

Alternate gene names: 74318487

Gene position: 2544158-2545867 (Clockwise)

Preceding gene: 74318484

Following gene: 74318504

Centisome position: 87.43

GC content: 68.89

Gene sequence:

>1710_bases
ATGCACGGCACGGATCTGATCACCACCATCGCCGCGGCTCTCGGGATGGCGCTCGTATTCGGCTTCCTCGCGGTACGCGT
CAAGCTGCCGGCCTTGGCCGGCTATCTGCTCGCGGGCATCGTCATCGGCCCCTTCACCCCCGGTTTCGTCGCCGACACGG
CGCTCGCGAGCGAACTCGCCGAAATCGGCGTGATCCTGCTGATGTTCGGCGTGGGGCTGCATTTCTCGCTCGATGACCTG
CTGTCGGTGAAGAAGATCGCGCTCCCCGGGGCGATCGTGCAGATCGCCGCGGCCACCGCCATGGGCGCGGCGCTGGCGGC
CTGGTGGGGCTGGAATCTGACGGCGGGGATCGTGTTCGGGCTCTCGCTCTCGACCGCGAGCACCGTCGTCCTGCTCAAGG
CGCTCGAAAGCCGCGGCATACTCGCGACGCCAAACGGGCGCATCGCGGTCGGCTGGCTCGTGGTCGAAGACCTGGCCATG
GTGCTCGTCCTGGTGCTGTTGCCGCCCGTGGCCGAAATCGCCAGCGGAAACAGCGCCGCGAGCCCCGGCTCGCTGGCAGG
GACACTCGCGCTCACCGTGGGCAAGGTGGCCATGTTCATCGCGCTGATGCTCGTCGTCGGCCGACGTTTCTTCCCCTGGC
TGCTGTGGCAGGTCGCGCGCACCGGCTCACGCGAATTGTTCACGCTCTGCGTCGTCGGCGCCGCGCTCGGCATCGCCTAC
GGCTCCTCCGCGCTGTTCGGGGTCTCGTTCGCGCTCGGTGCCTTTTTTGCCGGGATGGTGCTGCGCGAGTCGGCACTGAG
CTACCGCGCCGCGGAGGAGTCGCTGCCCTTGCGCGACGCCTTCGCCGTCCTGTTCTTCGTTTCGGTCGGCATGCTCTTCG
ATCCACGCGTGCTGGTCGAACAGCCGCTGCAGGTCCTGGCAGTCGTCGCAATCATCGTGTTCGGCAAATCGCTCGCCGCG
TTCCTGCTCGTGCTCGCCTTCCGCTATCCGCTCAATACCGCGTTGACCGTTTCGGCGAGCCTCGCGCAGATCGGCGAATT
CGCCTTCATCCTGGTCGGCCTCGGCGTCGCGCTCGGCATGTTGCCGGTGCAGGGCCAGAGCCTGATTCTCGCCGGTGCAT
TGATCTCGATCGCGCTCAATCCGCTCGTCTTCCGCGCCGTCGAGCCGGTGCAGGCGTGGCTGCGCCGTCACTCTGCGCGG
GCGCGCCGACTCGAGTCACCCGATGACCCTTTGGCCGAGCTTCCCGCAGACGTCGCCGCGGATACGCTGACCGATCACAT
CGTGCTGGCGGGATACGGGCGCGTCGGCCGGCGCATCGCCGACGCGCTCGACGCCGAGGGGCTGCCCTACATCGTCGCCG
AACAGCAGCGCGAGGCGGTCGAGAAGCTGCGCGGCCGTGGGCACAAGGCCGTCGTGGGCGACGCCTCGGACCCCGGCGTG
TTGATCCAGGCGCACGTCGCCCGGGCCCGGCTGCTCGTCATCGCCACGCCGGACAGCTTTCGCGCGCGCAAGATGATCGA
GATCGCGCGCACCCTCAATCCTGCCATCCGCGTCGTGGTCCGCAGCCACAGCGTCGACGAAGCGGCGTTGCTGCGCCGCG
AGCACGCGGCCGACGTGCTCGTCGGCGAAGAGGAGCTTGCGCAGAGCATGGTCCTCCGCGTGCGCGCGCATGCGCGGCAG
GCGGGGGCCGACGTGTTCGCACAGCCATGA

Upstream 100 bases:

>100_bases
GTAGACCTGCCGCGGAAATGAACCACCCTTGCCGGCGCGGGGGCGGCGGCGCCCGCGTTGCATCCGGTACACTCGGACGA
CCTCGACGAAAGGGTCTGGA

Downstream 100 bases:

>100_bases
GCGCCAGCTCCGTGCGCGCCGCGCGGAGCAATGCCTGAGCTCTGCCGCGGGCTTGCGCCCCGCACACCCAGGAACGGATG
AGGCCAGCGGGGAACGGAAG

Product: putative efflux pump/antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MHGTDLITTIAAALGMALVFGFLAVRVKLPALAGYLLAGIVIGPFTPGFVADTALASELAEIGVILLMFGVGLHFSLDDL
LSVKKIALPGAIVQIAAATAMGAALAAWWGWNLTAGIVFGLSLSTASTVVLLKALESRGILATPNGRIAVGWLVVEDLAM
VLVLVLLPPVAEIASGNSAASPGSLAGTLALTVGKVAMFIALMLVVGRRFFPWLLWQVARTGSRELFTLCVVGAALGIAY
GSSALFGVSFALGAFFAGMVLRESALSYRAAEESLPLRDAFAVLFFVSVGMLFDPRVLVEQPLQVLAVVAIIVFGKSLAA
FLLVLAFRYPLNTALTVSASLAQIGEFAFILVGLGVALGMLPVQGQSLILAGALISIALNPLVFRAVEPVQAWLRRHSAR
ARRLESPDDPLAELPADVAADTLTDHIVLAGYGRVGRRIADALDAEGLPYIVAEQQREAVEKLRGRGHKAVVGDASDPGV
LIQAHVARARLLVIATPDSFRARKMIEIARTLNPAIRVVVRSHSVDEAALLRREHAADVLVGEEELAQSMVLRVRAHARQ
AGADVFAQP

Sequences:

>Translated_569_residues
MHGTDLITTIAAALGMALVFGFLAVRVKLPALAGYLLAGIVIGPFTPGFVADTALASELAEIGVILLMFGVGLHFSLDDL
LSVKKIALPGAIVQIAAATAMGAALAAWWGWNLTAGIVFGLSLSTASTVVLLKALESRGILATPNGRIAVGWLVVEDLAM
VLVLVLLPPVAEIASGNSAASPGSLAGTLALTVGKVAMFIALMLVVGRRFFPWLLWQVARTGSRELFTLCVVGAALGIAY
GSSALFGVSFALGAFFAGMVLRESALSYRAAEESLPLRDAFAVLFFVSVGMLFDPRVLVEQPLQVLAVVAIIVFGKSLAA
FLLVLAFRYPLNTALTVSASLAQIGEFAFILVGLGVALGMLPVQGQSLILAGALISIALNPLVFRAVEPVQAWLRRHSAR
ARRLESPDDPLAELPADVAADTLTDHIVLAGYGRVGRRIADALDAEGLPYIVAEQQREAVEKLRGRGHKAVVGDASDPGV
LIQAHVARARLLVIATPDSFRARKMIEIARTLNPAIRVVVRSHSVDEAALLRREHAADVLVGEEELAQSMVLRVRAHARQ
AGADVFAQP
>Mature_569_residues
MHGTDLITTIAAALGMALVFGFLAVRVKLPALAGYLLAGIVIGPFTPGFVADTALASELAEIGVILLMFGVGLHFSLDDL
LSVKKIALPGAIVQIAAATAMGAALAAWWGWNLTAGIVFGLSLSTASTVVLLKALESRGILATPNGRIAVGWLVVEDLAM
VLVLVLLPPVAEIASGNSAASPGSLAGTLALTVGKVAMFIALMLVVGRRFFPWLLWQVARTGSRELFTLCVVGAALGIAY
GSSALFGVSFALGAFFAGMVLRESALSYRAAEESLPLRDAFAVLFFVSVGMLFDPRVLVEQPLQVLAVVAIIVFGKSLAA
FLLVLAFRYPLNTALTVSASLAQIGEFAFILVGLGVALGMLPVQGQSLILAGALISIALNPLVFRAVEPVQAWLRRHSAR
ARRLESPDDPLAELPADVAADTLTDHIVLAGYGRVGRRIADALDAEGLPYIVAEQQREAVEKLRGRGHKAVVGDASDPGV
LIQAHVARARLLVIATPDSFRARKMIEIARTLNPAIRVVVRSHSVDEAALLRREHAADVLVGEEELAQSMVLRVRAHARQ
AGADVFAQP

Specific function: Unknown

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=394, Percent_Identity=26.6497461928934, Blast_Score=92, Evalue=2e-18,
Organism=Escherichia coli, GI1786685, Length=550, Percent_Identity=54, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI1786232, Length=517, Percent_Identity=28.2398452611219, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1789749, Length=544, Percent_Identity=28.3088235294118, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 59856; Mature: 59856

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGTDLITTIAAALGMALVFGFLAVRVKLPALAGYLLAGIVIGPFTPGFVADTALASELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EIGVILLMFGVGLHFSLDDLLSVKKIALPGAIVQIAAATAMGAALAAWWGWNLTAGIVFG
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LSLSTASTVVLLKALESRGILATPNGRIAVGWLVVEDLAMVLVLVLLPPVAEIASGNSAA
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
SPGSLAGTLALTVGKVAMFIALMLVVGRRFFPWLLWQVARTGSRELFTLCVVGAALGIAY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GSSALFGVSFALGAFFAGMVLRESALSYRAAEESLPLRDAFAVLFFVSVGMLFDPRVLVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHH
QPLQVLAVVAIIVFGKSLAAFLLVLAFRYPLNTALTVSASLAQIGEFAFILVGLGVALGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPVQGQSLILAGALISIALNPLVFRAVEPVQAWLRRHSARARRLESPDDPLAELPADVAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHH
DTLTDHIVLAGYGRVGRRIADALDAEGLPYIVAEQQREAVEKLRGRGHKAVVGDASDPGV
HHHHCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCE
LIQAHVARARLLVIATPDSFRARKMIEIARTLNPAIRVVVRSHSVDEAALLRREHAADVL
EEEEECCEEEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHE
VGEEELAQSMVLRVRAHARQAGADVFAQP
ECHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MHGTDLITTIAAALGMALVFGFLAVRVKLPALAGYLLAGIVIGPFTPGFVADTALASELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EIGVILLMFGVGLHFSLDDLLSVKKIALPGAIVQIAAATAMGAALAAWWGWNLTAGIVFG
HHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LSLSTASTVVLLKALESRGILATPNGRIAVGWLVVEDLAMVLVLVLLPPVAEIASGNSAA
HHHHHHHHHHHHHHHHCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
SPGSLAGTLALTVGKVAMFIALMLVVGRRFFPWLLWQVARTGSRELFTLCVVGAALGIAY
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
GSSALFGVSFALGAFFAGMVLRESALSYRAAEESLPLRDAFAVLFFVSVGMLFDPRVLVE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHH
QPLQVLAVVAIIVFGKSLAAFLLVLAFRYPLNTALTVSASLAQIGEFAFILVGLGVALGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LPVQGQSLILAGALISIALNPLVFRAVEPVQAWLRRHSARARRLESPDDPLAELPADVAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHH
DTLTDHIVLAGYGRVGRRIADALDAEGLPYIVAEQQREAVEKLRGRGHKAVVGDASDPGV
HHHHCCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCE
LIQAHVARARLLVIATPDSFRARKMIEIARTLNPAIRVVVRSHSVDEAALLRREHAADVL
EEEEECCEEEEEEEECCCCHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHHHHE
VGEEELAQSMVLRVRAHARQAGADVFAQP
ECHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]