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The map label for this gene is cbbI

Identifier: 74318382

GI number: 74318382

Start: 2439662

End: 2440318

Strand: Direct

Name: cbbI

Synonym: Tbd_2364

Alternate gene names: 74318382

Gene position: 2439662-2440318 (Clockwise)

Preceding gene: 74318375

Following gene: 74318391

Centisome position: 83.84

GC content: 64.69

Gene sequence:

>657_bases
ATGACCCAAGACGAAATGAAGCGAGCCGTAGCGCGTGCTGCGGTGGATTATGCCAAGGGCGGCATCATCGGCGTAGGAAC
CGGCTCGACCGCGAACCATTTCATCGACGCCCTGGCCGAAGTCAAGGGGCGCATCGAGGGCACGGTGGCGAGTTCCGAGG
CGACGGCGGCGCGGCTGAAAAGCCACGGCATACAGGTGCTCGACCTCAACAGCGTCGGAGAGCTCGAGGTCTACGTCGAT
GGGGCTGACGAGATCACGCAGCATTTCGCGATGATCAAGGGCGGCGGCGGCGCGCTGACGCGGGAAAAGATCGTTGCGGC
GTGCAGCAAGCAATTCGTCTGTATCGCCGACGACAGCAAGCTCGTCGACGTTCTCGGCAAATTCCCGCTGCCGGTCGAGG
TGATCCCGATGGCCCGCTCGCACGTCGCGCGGGAGCTCGTGAAGCTCGGCGGCCAGCCCCGCCTGCGCGAGGGCTTCACG
ACCGACAACGGCAACGTGATCCTCGACGTGCACAACCTTTCGATCATCGACCCGGTATCGCTCGAGACCGCGATCAACCA
GATCGTCGGCGTGGTCACCAACGGCCTCTTCGCCCGGCGCGGCGCCGACGTGCTGTTGCTCGGCACGTCGACCGGGGTCA
AGACCTTCACGAGATAG

Upstream 100 bases:

>100_bases
TAGTCGTCTGGGTGGCTCATGGCGGGCGGCTGAGGTGCGTTTGTAAAAAGGGTGCGATGCCGCTATCTTAGTGGGCTGGA
CTCAAATCGACGAAAACATC

Downstream 100 bases:

>100_bases
TCACTGCGGACGCTCGGCCTGGTCGGGCGTCTCGCCCTCATCCGGCTTCGGTTCCACCGGCACGCGATATTTCTCGGTCG
CCCACTGACCAAGATCGATG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTQDEMKRAVARAAVDYAKGGIIGVGTGSTANHFIDALAEVKGRIEGTVASSEATAARLKSHGIQVLDLNSVGELEVYVD
GADEITQHFAMIKGGGGALTREKIVAACSKQFVCIADDSKLVDVLGKFPLPVEVIPMARSHVARELVKLGGQPRLREGFT
TDNGNVILDVHNLSIIDPVSLETAINQIVGVVTNGLFARRGADVLLLGTSTGVKTFTR

Sequences:

>Translated_218_residues
MTQDEMKRAVARAAVDYAKGGIIGVGTGSTANHFIDALAEVKGRIEGTVASSEATAARLKSHGIQVLDLNSVGELEVYVD
GADEITQHFAMIKGGGGALTREKIVAACSKQFVCIADDSKLVDVLGKFPLPVEVIPMARSHVARELVKLGGQPRLREGFT
TDNGNVILDVHNLSIIDPVSLETAINQIVGVVTNGLFARRGADVLLLGTSTGVKTFTR
>Mature_217_residues
TQDEMKRAVARAAVDYAKGGIIGVGTGSTANHFIDALAEVKGRIEGTVASSEATAARLKSHGIQVLDLNSVGELEVYVDG
ADEITQHFAMIKGGGGALTREKIVAACSKQFVCIADDSKLVDVLGKFPLPVEVIPMARSHVARELVKLGGQPRLREGFTT
DNGNVILDVHNLSIIDPVSLETAINQIVGVVTNGLFARRGADVLLLGTSTGVKTFTR

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=214, Percent_Identity=38.785046728972, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1789280, Length=219, Percent_Identity=66.6666666666667, Blast_Score=296, Evalue=5e-82,
Organism=Caenorhabditis elegans, GI17551758, Length=208, Percent_Identity=36.5384615384615, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6324669, Length=234, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI281364072, Length=193, Percent_Identity=34.1968911917098, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_THIDA (Q3SGD3)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_316122.1
- ProteinModelPortal:   Q3SGD3
- SMR:   Q3SGD3
- STRING:   Q3SGD3
- GeneID:   3671857
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_2364
- NMPDR:   fig|292415.3.peg.2437
- eggNOG:   COG0120
- HOGENOM:   HBG515603
- OMA:   DKSIVGV
- PhylomeDB:   Q3SGD3
- ProtClustDB:   PRK00702
- BioCyc:   TDEN292415:TBD_2364-MONOMER
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 22979; Mature: 22848

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKRAVARAAVDYAKGGIIGVGTGSTANHFIDALAEVKGRIEGTVASSEATAARLK
CCHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCEEEECCHHHHHHHH
SHGIQVLDLNSVGELEVYVDGADEITQHFAMIKGGGGALTREKIVAACSKQFVCIADDSK
HCCEEEEEECCCCEEEEEECCHHHHHHHHHHEECCCCCHHHHHHHHHHCCCEEEEECCCH
LVDVLGKFPLPVEVIPMARSHVARELVKLGGQPRLREGFTTDNGNVILDVHNLSIIDPVS
HHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEECCCH
LETAINQIVGVVTNGLFARRGADVLLLGTSTGVKTFTR
HHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQDEMKRAVARAAVDYAKGGIIGVGTGSTANHFIDALAEVKGRIEGTVASSEATAARLK
CHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHCEEEECCHHHHHHHH
SHGIQVLDLNSVGELEVYVDGADEITQHFAMIKGGGGALTREKIVAACSKQFVCIADDSK
HCCEEEEEECCCCEEEEEECCHHHHHHHHHHEECCCCCHHHHHHHHHHCCCEEEEECCCH
LVDVLGKFPLPVEVIPMARSHVARELVKLGGQPRLREGFTTDNGNVILDVHNLSIIDPVS
HHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCEEECCCH
LETAINQIVGVVTNGLFARRGADVLLLGTSTGVKTFTR
HHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA