Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 74318338

GI number: 74318338

Start: 2394864

End: 2396009

Strand: Reverse

Name: mdtA [H]

Synonym: Tbd_2320

Alternate gene names: 74318338

Gene position: 2396009-2394864 (Counterclockwise)

Preceding gene: 74318339

Following gene: 74318337

Centisome position: 82.34

GC content: 74.17

Gene sequence:

>1146_bases
ATGAAACTGCGCATTCTTGTGTCGATCGTCGTGCTGGCGCTGCTCGCTGCGGTCGTTTATCGCGTCCAGCAGCAAGGCGC
GGGCGAGCGCCGCGGCAGCGGCGACCGCGCGCTCGCCGTGCGCGCGGTCCCGGTCGAAGAGCGCGATTTCCCGCGTGTCC
TCGATCTTCCCGGCACGCTCGAAGCCGCGCAACAGGTCGCGATCGTCGCTCAGGTCGGCGGCACCGTGCTGCGGCAACAC
GTCGAGGAGGGCGACGCGGTCGCCGCGGGCAAGATCCTCTTTACGCTCGACGCACGCCCGGCGCGCGCGCGCATCGCGCA
GAGCCAGGCCACCCTCGCCGGTGCGCTCGCCGAGGCCGAGGAGGCCGAACGCCAGCTCCGTCGCCTCGACCCGCTGATGG
CCTCCGGCTACATCAGCCGCCAGGAATACGAGACCGCACGCGTCGCGCTCGAGGCGGCACGGGCGCGCGCGGGCGCGGCC
CGCGGCGAGCTCGAGGCCGCCCGGCTCGACGTCGCATACGCCGCGATACGCGCACCGATCGCCGGCCGCGTCGGACGGAT
ATCCGTGCGGCCGGGCAGCCTCGTGCAGGCGGGCGGCGAACCGTTGACGACGCTAATCGCGCCCGGGACGCTCGACGTGC
GGGCGAGCGTCGCCCAGCAGGACTGGCCCGAACTCGCGGCCGCCCGGGAGCAGGGGCGCGTCACCGCCGAAGTCTTCCTC
GACACCCATCCGGGCGCGCGCGCCCGTGGCGAGCTCGTCTTCGTCGACACGCAGATCGACGCGCCGACCGGCGCCGTGCC
GATCAAGGTCAGGCTCGCCGACCCGCCGCTCGGCCTGCTGTCGGGCCAGAGCGTGCGCGTGCGCCTGCTTCTCGGCAGCG
ATCCCGGTGCCCGGGTCGTTCCCGAGGCCGCGCTGCAGCACGGGCAGGCGGGCAGCTACGTCTACGTCGTGCGCGGGGGC
AAGGCCGTCGTCCAGCCGGTGACCTCGGTGCGCAGCCTCGACGGCGAACACATGGTCGAGGGCGAGCTGCGTGCCGGCGA
ATCCGTGCTCACCGAAATCCCCCAGCGGCTCAAGGCCGGCGACGCGGTCAGGCTCGAGCCCGCGGCGGGCGCCGGTGCCC
GGACCGGAACGGCGCGTCCGCGGTGA

Upstream 100 bases:

>100_bases
GCCAGGTGCGCGCCCAGTCCGACAGCGACTGGCTCGCCGCGTTTTCGGCCCTCAATCACGCGCTCGGACGTTTGCCGGGC
GCCTCACCGGGAACGCCGCC

Downstream 100 bases:

>100_bases
ACCTGTCGCGGCGCTTCATCGAGCGGCCGGTCGCCACGCTCATGCTGGCGCTGGCGATGGCCTTGTTCGGCGCGCTCGCC
TACACCCAGCTGCCGATTAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKLRILVSIVVLALLAAVVYRVQQQGAGERRGSGDRALAVRAVPVEERDFPRVLDLPGTLEAAQQVAIVAQVGGTVLRQH
VEEGDAVAAGKILFTLDARPARARIAQSQATLAGALAEAEEAERQLRRLDPLMASGYISRQEYETARVALEAARARAGAA
RGELEAARLDVAYAAIRAPIAGRVGRISVRPGSLVQAGGEPLTTLIAPGTLDVRASVAQQDWPELAAAREQGRVTAEVFL
DTHPGARARGELVFVDTQIDAPTGAVPIKVRLADPPLGLLSGQSVRVRLLLGSDPGARVVPEAALQHGQAGSYVYVVRGG
KAVVQPVTSVRSLDGEHMVEGELRAGESVLTEIPQRLKAGDAVRLEPAAGAGARTGTARPR

Sequences:

>Translated_381_residues
MKLRILVSIVVLALLAAVVYRVQQQGAGERRGSGDRALAVRAVPVEERDFPRVLDLPGTLEAAQQVAIVAQVGGTVLRQH
VEEGDAVAAGKILFTLDARPARARIAQSQATLAGALAEAEEAERQLRRLDPLMASGYISRQEYETARVALEAARARAGAA
RGELEAARLDVAYAAIRAPIAGRVGRISVRPGSLVQAGGEPLTTLIAPGTLDVRASVAQQDWPELAAAREQGRVTAEVFL
DTHPGARARGELVFVDTQIDAPTGAVPIKVRLADPPLGLLSGQSVRVRLLLGSDPGARVVPEAALQHGQAGSYVYVVRGG
KAVVQPVTSVRSLDGEHMVEGELRAGESVLTEIPQRLKAGDAVRLEPAAGAGARTGTARPR
>Mature_381_residues
MKLRILVSIVVLALLAAVVYRVQQQGAGERRGSGDRALAVRAVPVEERDFPRVLDLPGTLEAAQQVAIVAQVGGTVLRQH
VEEGDAVAAGKILFTLDARPARARIAQSQATLAGALAEAEEAERQLRRLDPLMASGYISRQEYETARVALEAARARAGAA
RGELEAARLDVAYAAIRAPIAGRVGRISVRPGSLVQAGGEPLTTLIAPGTLDVRASVAQQDWPELAAAREQGRVTAEVFL
DTHPGARARGELVFVDTQIDAPTGAVPIKVRLADPPLGLLSGQSVRVRLLLGSDPGARVVPEAALQHGQAGSYVYVVRGG
KAVVQPVTSVRSLDGEHMVEGELRAGESVLTEIPQRLKAGDAVRLEPAAGAGARTGTARPR

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=353, Percent_Identity=29.4617563739377, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789929, Length=333, Percent_Identity=29.1291291291291, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789665, Length=335, Percent_Identity=27.7611940298507, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786668, Length=343, Percent_Identity=29.7376093294461, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87081951, Length=151, Percent_Identity=31.1258278145695, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40016; Mature: 40016

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRILVSIVVLALLAAVVYRVQQQGAGERRGSGDRALAVRAVPVEERDFPRVLDLPGTL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCHH
EAAQQVAIVAQVGGTVLRQHVEEGDAVAAGKILFTLDARPARARIAQSQATLAGALAEAE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
EAERQLRRLDPLMASGYISRQEYETARVALEAARARAGAARGELEAARLDVAYAAIRAPI
HHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
AGRVGRISVRPGSLVQAGGEPLTTLIAPGTLDVRASVAQQDWPELAAAREQGRVTAEVFL
CCCCCEEEECCCHHHHCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEEE
DTHPGARARGELVFVDTQIDAPTGAVPIKVRLADPPLGLLSGQSVRVRLLLGSDPGARVV
ECCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCC
PEAALQHGQAGSYVYVVRGGKAVVQPVTSVRSLDGEHMVEGELRAGESVLTEIPQRLKAG
CHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEECCHHHCCHHHHHHHHHHHCCC
DAVRLEPAAGAGARTGTARPR
CCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLRILVSIVVLALLAAVVYRVQQQGAGERRGSGDRALAVRAVPVEERDFPRVLDLPGTL
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCHH
EAAQQVAIVAQVGGTVLRQHVEEGDAVAAGKILFTLDARPARARIAQSQATLAGALAEAE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
EAERQLRRLDPLMASGYISRQEYETARVALEAARARAGAARGELEAARLDVAYAAIRAPI
HHHHHHHHHCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
AGRVGRISVRPGSLVQAGGEPLTTLIAPGTLDVRASVAQQDWPELAAAREQGRVTAEVFL
CCCCCEEEECCCHHHHCCCCCEEEEECCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEEE
DTHPGARARGELVFVDTQIDAPTGAVPIKVRLADPPLGLLSGQSVRVRLLLGSDPGARVV
ECCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCC
PEAALQHGQAGSYVYVVRGGKAVVQPVTSVRSLDGEHMVEGELRAGESVLTEIPQRLKAG
CHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCEECCHHHCCHHHHHHHHHHHCCC
DAVRLEPAAGAGARTGTARPR
CCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA