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The map label for this gene is slyD [H]

Identifier: 74318298

GI number: 74318298

Start: 2353694

End: 2354203

Strand: Reverse

Name: slyD [H]

Synonym: Tbd_2280

Alternate gene names: 74318298

Gene position: 2354203-2353694 (Counterclockwise)

Preceding gene: 74318299

Following gene: 74318296

Centisome position: 80.91

GC content: 59.61

Gene sequence:

>510_bases
ATGAAAGCCATCATCGAAGCCAACAAATACGTCGAACTGACCTACAAGGTCATCGACCAGAAAACCTGCCAGGTGCTGAC
GCAGGTCGAGTTTCCGCTGGGCTACGTCCACGGCGTCAACGAGATATTGTCGCCGCGCGTCATGGACGCGCTGGAAGGCA
AATCCGAGGGCGACGTCATCGAGGTCCCCATCGACTGCAACGACATCTATGGCCCGCGCGATGAATCCCTCGTGATCATC
GAAGCGATCGCGAACGTCCCCGAGGCCTACCGCGAAGTCGGCACCGCCATCCTGATGGAAAACGACGCCGGGCAAACCAA
AAGCTTTCTGGTGACGCGGGTCGACCACAGAACAGTGACGATAGACGGCAACAACCCGCTGTGCGGCCGGCAGGTCGTTT
TCAAGCTCGAGATCCTGATGGTGCGTGACGCCACCGACGCGGAAATCCGCTACGGTGGCAAGGTGGAAGCGCCGCCAGAC
CTCAACAACTGTCGCGCCGTTCCCGTTTGA

Upstream 100 bases:

>100_bases
CAAGCGGGAAGGTGAATGGCTCGGGCGGCTGGTGCTGGGCTATGAACAAGGCGAGGTGCGCATCTTTGCCGCCTCCATAT
TCTGAACGGCCGGACACCTC

Downstream 100 bases:

>100_bases
CTGGCGTTGAAGCCGCCTGTTTCCGAGTCCCATTTTTTCGAGAGGTCATCATGAGCGAACCCACCAAAACCAGGCGTCCG
GTTCCCGAAGGCAAATCGCG

Product: putative peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MKAIIEANKYVELTYKVIDQKTCQVLTQVEFPLGYVHGVNEILSPRVMDALEGKSEGDVIEVPIDCNDIYGPRDESLVII
EAIANVPEAYREVGTAILMENDAGQTKSFLVTRVDHRTVTIDGNNPLCGRQVVFKLEILMVRDATDAEIRYGGKVEAPPD
LNNCRAVPV

Sequences:

>Translated_169_residues
MKAIIEANKYVELTYKVIDQKTCQVLTQVEFPLGYVHGVNEILSPRVMDALEGKSEGDVIEVPIDCNDIYGPRDESLVII
EAIANVPEAYREVGTAILMENDAGQTKSFLVTRVDHRTVTIDGNNPLCGRQVVFKLEILMVRDATDAEIRYGGKVEAPPD
LNNCRAVPV
>Mature_169_residues
MKAIIEANKYVELTYKVIDQKTCQVLTQVEFPLGYVHGVNEILSPRVMDALEGKSEGDVIEVPIDCNDIYGPRDESLVII
EAIANVPEAYREVGTAILMENDAGQTKSFLVTRVDHRTVTIDGNNPLCGRQVVFKLEILMVRDATDAEIRYGGKVEAPPD
LNNCRAVPV

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=143, Percent_Identity=34.2657342657343, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18704; Mature: 18704

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIIEANKYVELTYKVIDQKTCQVLTQVEFPLGYVHGVNEILSPRVMDALEGKSEGDVI
CCCEECCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHCCCCCCCEE
EVPIDCNDIYGPRDESLVIIEAIANVPEAYREVGTAILMENDAGQTKSFLVTRVDHRTVT
EEECCCCCCCCCCCCCEEEEHHHHCCHHHHHHHCEEEEEECCCCCCCEEEEEEECCEEEE
IDGNNPLCGRQVVFKLEILMVRDATDAEIRYGGKVEAPPDLNNCRAVPV
ECCCCCCCCCEEEEEEEEEEEECCCCCEEEECCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MKAIIEANKYVELTYKVIDQKTCQVLTQVEFPLGYVHGVNEILSPRVMDALEGKSEGDVI
CCCEECCCCEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHCCCCCCCEE
EVPIDCNDIYGPRDESLVIIEAIANVPEAYREVGTAILMENDAGQTKSFLVTRVDHRTVT
EEECCCCCCCCCCCCCEEEEHHHHCCHHHHHHHCEEEEEECCCCCCCEEEEEEECCEEEE
IDGNNPLCGRQVVFKLEILMVRDATDAEIRYGGKVEAPPDLNNCRAVPV
ECCCCCCCCCEEEEEEEEEEEECCCCCEEEECCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]